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公开(公告)号:CA2738981A1
公开(公告)日:2010-04-08
申请号:CA2738981
申请日:2009-09-16
Applicant: TORAY INDUSTRIES
Inventor: MIMITSUKA TAKASHI , ISHII KENTARO , MORITA KEN , HIGASA MASASHI , SAWAI KENJI , SAWAI HIDEKI , YAMADA KATSUSHIGE , MINEGISHI SHINICHI
Abstract: To control the flow rate of a liquid culture medium in a membrane separation tank without affecting the culture conditions in a culture tank and to increase the production efficiency of a chemical by inhibiting the precipitation of a microorganism or culture cells, provided is a method for producing a chemical which comprises culturing a microorganism or culture cells in a culture tank, feeding the liquid culture medium from the culture tank to a membrane separation tank and filtering the same through a separation membrane, collecting a fermentation product as the chemical from the permeate and, at the same time, returning the unfiltered liquid culture medium not having been filtered in such a manner as combining the same with the liquid culture medium in the upstream side of the membrane separation tank, wherein a portion of the liquid culture medium fed from the culture tank is passed outside the membrane separation tank depending on the inflow side pressure of the membrane separation tank.
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公开(公告)号:AU2009211772A1
公开(公告)日:2009-08-13
申请号:AU2009211772
申请日:2009-02-03
Applicant: TORAY INDUSTRIES
Inventor: MIMITSUKA TAKASHI , YAMADA KATSUSHIGE , MORITA KEN , SASAKI NANAMI , SAWAI HIDEKI
Abstract: By a method for producing lactic acid wherein culture of polyploid yeast having a capacity to produce lactic acid is filtered through a porous membrane having an average pore size of not less than 0.01 µm and less than 1 µm and the product is recovered from the filtrate, while the unfiltered liquid is retained in or returned to the culture and a fermentation feedstock is added to the culture, it is possible to remarkably and stably enhance the efficiency of production of lactic acid by fermentation for a long time at a low cost.
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公开(公告)号:ES2765889T3
公开(公告)日:2020-06-11
申请号:ES16196147
申请日:2009-12-25
Applicant: TORAY INDUSTRIES
Inventor: SAWAI KENJI , SAWAI HIDEKI , MIMITSUKA TAKASHI , ITO MASATERU , YAMADA KATSUSHIGE , KAWAMURA KENJI , MINEGISHI SHIN-ICHI , NAKAGAWA IZUMI , NAGANO TATSUYA
Abstract: Solución acuosa de ácido láctico al 90 % que contiene metanol a una concentración no superior a 50 ppm, ácido pirúvico a una concentración no superior a 500 ppm, furfural a una concentración no superior a 15 ppm, 5-hidroximetilfurfural a una concentración no superior a 15 ppm, lactato de metilo a una concentración no superior a 600 ppm, ácido acético a una concentración no superior a 500 ppm y ácido 2-hidroxibutírico a una concentración no superior a 500 ppm, en la que la pureza óptica de dicho ácido láctico no es inferior al 99,9 %.
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公开(公告)号:CA2738981C
公开(公告)日:2018-07-31
申请号:CA2738981
申请日:2009-09-16
Applicant: TORAY INDUSTRIES
Inventor: MIMITSUKA TAKASHI , ISHII KENTARO , MORITA KEN , HIGASA MASASHI , SAWAI KENJI , SAWAI HIDEKI , YAMADA KATSUSHIGE , MINEGISHI SHINICHI
Abstract: To control flow velocity of a culture liquid inside a membrane separation tank without giving influences to culture conditions in the fermentation tank, and also suppress precipitation of microorganisms or culture cells so that the production efficiency of the chemical product can be improved, in a method for producing a chemical product including the steps of : cultivating microorganisms or culture cells in a fermentation tank; transferring a culture liquid from the fermentation tank to a membrane separation tank so as to filter the culture liquid through a separation membrane; and collecting a fermentation product from a filtration liquid as the chemical product while refluxing an unfiltered culture liquid that has not been filtered so as to be joined to the culture liquid on an upstream side of the membrane separation tank, one portion of the culture liquid to be transferred from the fermentation tank is allowed to bypass the membrane separation tank depending on a pressure at the culture liquid flow-in side of the membrane separation tank.
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公开(公告)号:MY160554A
公开(公告)日:2017-03-15
申请号:MYPI2012003760
申请日:2011-02-22
Applicant: TORAY INDUSTRIES
Inventor: MIMITSUKA TAKASHI , SUDA KAZUMI , SAWAI HIDEKI
Abstract: BY A METHOD FOR PRODUCING CADAVERINE BY CULTURING A MICROORGANISM THAT EXTRACELLULARLY SECRETES LYSINE DECARBOXYLASE, BY-PRODUCTION OF LYSINE IS SUPPRESSED, THE YIELD OF CADAVERINE RELATIVE TO GLUCOSE CONSUMPTION IS IMPROVED COMPARED TO CONVENTIONAL PRODUCTION METHODS, AND FURTHER, THE LOAD ON THE PURIFICATION STEP IN PURIFICATION OF CADAVERINE AS A RAW MATERIAL FOR POLYAMIDE CAN BE REDUCED.
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公开(公告)号:AU2014299919A1
公开(公告)日:2016-01-21
申请号:AU2014299919
申请日:2014-06-23
Applicant: TORAY INDUSTRIES
Inventor: MIMITSUKA TAKASHI , HAYAKAWA HIROSHI , MORITA KEN , YAMAMOTO YUKI , OTSUKA KENICHI
Abstract: This continuous sterilization device sterilizes a member constituting a flow path by causing a sterilization medium for sterilizing the member to flow through the member, causes a sterile liquid subjected to sterilization treatment to flow through a pipe, while performing a series of treatments including heat treatment, holding treatment, and cooling treatment on the sterile liquid, controls the flow rate, temperature, and pressure thereof to preset conditions, and switches a liquid to flow through the flow path from the sterile liquid to a liquid to be sterilized.
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公开(公告)号:SG2013095930A
公开(公告)日:2015-07-30
申请号:SG2013095930
申请日:2009-12-25
Applicant: TORAY INDUSTRIES
Inventor: SAWAI KENJI , SAWAI HIDEKI , MIMITSUKA TAKASHI , ITO MASATERU , YAMADA KATSUSHIGE , KAWAMURA KENJI , MINEGISHI SHIN-ICHI , NAKAGAWA IZUMI , NAGANO TATSUYA
Abstract: Lactic acid obtained by a method for producing lactic acid, the method comprising: (A) a step of continuous fermentation wherein a fermentation culture medium of a microorganism having an ability of lactic acid fermentation is filtered through a porous membrane having an average pore size of not less than 0.01 µm and less than 1 µm with a transmembrane pressure difference within the range of 0.1 to 20 kPa, and the permeate is collected, while retaining the non-permeated liquid in or returning the non-permeated liquid to the culture, and adding a fermentation feedstock to the culture; (B) a step of filtering the permeate obtained in Step (A) through a nanofiltration membrane; and (C) a step of distilling the permeate obtained in Step (B) under a pressure of not less than 1 Pa and not more than atmospheric pressure, at 25°C to 200°C to recover lactic acid; comprises only small amounts of impurities, and a polylactic acid obtained using the lactic acid as a raw material has excellent thermal stability, mechanical strength and hue.
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公开(公告)号:AU2009299152B2
公开(公告)日:2015-07-16
申请号:AU2009299152
申请日:2009-09-16
Applicant: TORAY INDUSTRIES
Inventor: MIMITSUKA TAKASHI , ISHII KENTARO , MORITA KEN , HIGASA MASASHI , SAWAI KENJI , SAWAI HIDEKI , YAMADA KATSUSHIGE , MINEGISHI SHINICHI
Abstract: To control the flow rate of a liquid culture medium in a membrane separation tank without affecting the culture conditions in a culture tank and to increase the production efficiency of a chemical by inhibiting the precipitation of a microorganism or culture cells, provided is a method for producing a chemical which comprises culturing a microorganism or culture cells in a culture tank, feeding the liquid culture medium from the culture tank to a membrane separation tank and filtering the same through a separation membrane, collecting a fermentation product as the chemical from the permeate and, at the same time, returning the unfiltered liquid culture medium not having been filtered in such a manner as combining the same with the liquid culture medium in the upstream side of the membrane separation tank, wherein a portion of the liquid culture medium fed from the culture tank is passed outside the membrane separation tank depending on the inflow side pressure of the membrane separation tank.
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公开(公告)号:CA2790919A1
公开(公告)日:2011-09-01
申请号:CA2790919
申请日:2011-02-22
Applicant: TORAY INDUSTRIES
Inventor: MIMITSUKA TAKASHI , SUDA KAZUMI , SAWAI HIDEKI
Abstract: Disclosed is a process for producing cadaverine, characterized by culturing a microorganism capable of secreting lysine decarboxylase outside cells thereof. According to the process, the by-production of lysine can be prevented, the yield of cadaverine on glucose consumption is improved compared with those in conventional processes, and the load in a purification step for purifying cadaverine as a polyamide raw material can be reduced.
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公开(公告)号:BRPI0707027A2
公开(公告)日:2011-04-19
申请号:BRPI0707027
申请日:2007-02-16
Applicant: TORAY INDUSTRIES
Inventor: SAWAI HIDEKI , YAMADA KATSUSHIGE , MIMITSUKA TAKASHI , SAWAI KENJI , YONEHARA TETSU , ITO YOHITO , HENMI MASAHIRO
IPC: C12P7/56 , C12M1/12 , C12N15/09 , C12P7/06 , C12P7/46 , C12P7/50 , C12P13/00 , C12P13/08 , C12P19/30
Abstract: The invention provides a method of producing a chemical product through continuous fermentation which includes filtering a culture of a microorganism or cultured cells with a separation membrane to recover a product from a filtrate and simultaneously retaining a nonfiltered fluid in, or refluxing it to, the culture, and adding fermentation materials to the culture, wherein a porous membrane having an average pore size of 0.01 µm or more to less than 1 µm is used as the separation membrane and the filtration is conducted with a transmembrane pressure difference in the range of 0.1 to 20 kPa. According to this method, the fermentation productivity of the chemical product can be largely elevated at high stability and a low cost.
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