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公开(公告)号：CA2638780C
公开(公告)日：2017-11-21
申请号：CA2638780
申请日：2007-02-16
Applicant: TORAY INDUSTRIES
Inventor： SAWAI HIDEKI , YAMADA KATSUSHIGE , MIMITSUKA TAKASHI , SAWAI KENJI , YONEHARA TETSU , ITO YOHITO , HENMI MASAHIRO
IPC: C12P7/56 , C12M1/12 , C12N15/09 , C12P7/06 , C12P7/18 , C12P7/46 , C12P7/50 , C12P13/00 , C12P13/08 , C12P19/30
Abstract: The invention provides a method of producing a chemical product through continuous fermentation which includes filtering a culture of a microorganism or cultured cells with a separation membrane to recover a product from a filtrate and simultaneously retaining a nonfiltered fluid in, or refluxing it to, the culture, and adding fermentation materials to the culture, wherein a porous membrane having an average pore size of 0.01 µm or more to less than 1 µm is used as the separation membrane and the filtration is conducted with a transmembrane pressure difference in the range of 0.1 to 20 kPa. According to this method, the fermentation productivity of the chemical product can be largely elevated at high stability and a low cost.
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公开(公告)号：BR112012021070A2
公开(公告)日：2015-10-06
申请号：BR112012021070
申请日：2011-02-22
Applicant: TORAY INDUSTRIES
Inventor： SAWAI HIDEKI , SUDA KAZUMI , MIMITSUKA TAKASHI
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公开(公告)号：ES2527980T3
公开(公告)日：2015-02-02
申请号：ES09013960
申请日：2006-09-04
Applicant: TORAY INDUSTRIES
Inventor： SAWAI HIDEKI , SAWAI KENJI , SONOKI TOMONORI , HATAHIRA SATOKO
Abstract: Levadura que comprende un gen introducido que codifica una L-lactato deshidrogenasa de Xenopus laevis, en la que el gen que codifica la L-lactato deshidrogenasa es un gen que codifica una L-lactato deshidrogenasa de Xenopus laevis IdhA, IdhB o IdhC.
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公开(公告)号：CA2735505A1
公开(公告)日：2012-09-30
申请号：CA2735505
申请日：2011-03-30
Applicant: TORAY INDUSTRIES
Inventor： MORITA IZUMI , ITO MASATERU , SAWAI HIDEKI , MINEGISHI SHINICHI , YAMADA KATSUSHIGE , KAWAMURA KENJI
Abstract: A method of producing butanol, which has a step of removing impurities contained in a butanol-containing solution, is provided. In the method, a butanol--containing solution is filtered through a nanofiltration membrane. Then the butanol-containing solution is collected from the permeate flow of the nanofiltration membrane.
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公开(公告)号：CA2735637A1
公开(公告)日：2012-09-29
申请号：CA2735637
申请日：2011-03-29
Applicant: TORAY INDUSTRIES
Inventor： MORITA IZUMI , ITO MASATERU , SAWAI HIDEKI , MINEGISHI SHINICHI , YAMADA KATSUSHIGE , KAWAMURA KENJI , YAMANE SHINICHI
Abstract: A method for producing a diol or triol, which has a step of removing impurities contained in a diol- or triol-containing solution, is provided. In the method, a diol-or triol-containing solution is filtered through a nanofiltration membrane having a polyamide-containing functional layer. The diol-or triol--containing solution is then collected from the permeate flow of the nanofiltration membrane.
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Patent Agency Ranking
公开(公告)号：AU2006300688B2
公开(公告)日：2012-07-19
申请号：AU2006300688
申请日：2006-09-04
Applicant: TORAY INDUSTRIES
Inventor： SONOKI TOMONORI , SAWAI HIDEKI , HATAHIRA SATOKO , SAWAI KENJI
Abstract: A yeast having a human- or frog-origin gene encoding L-lactate dehydrogenase transferred thereinto. By producing lactic acid by using the above-described gene and a method of producing lactic acid with the use of the enzyme, it is possible to efficiently produce lactic acid which is widely usable. As a result, lactic acid can be provided at a lower cost.
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公开(公告)号：AU2010319104A1
公开(公告)日：2012-05-17
申请号：AU2010319104
申请日：2010-11-10
Applicant: TORAY INDUSTRIES
Inventor： TAKEUCHI NORIHIRO , MINEGISHI SHIN-ICHI , CHEON JIHOON , NISHIDA MAKOTO , MIMITSUKA TAKASHI , SUZUKI HIRONOBU , YAMADA KATSUSHIGE , SAWAI HIDEKI , KUMO ICHIRO
Abstract: Disclosed is a hollow fiber membrane module (1) for use in the production of a chemical substance, which can be used in the continuous fermentation that comprises filtrating a fermentation culture of a microorganism or a cultured cell through a hollow fiber membrane, collecting a chemical substance from a filtrate, retaining a concentrated solution in the fermentation culture or refluxing the concentrated solution, and further adding a fermentation raw material to the fermentation culture. In the hollow fiber membrane module (1), multiple hollow fiber membrane bundles are accommodated in a tubular case, at least one end part of each of the hollow fiber membrane bundles is fixed onto the tubular case in such a manner that the end surface of each of the hollow fiber membranes is opened by means of a hollow-fiber-membrane-bundling material, and the hollow-fiber-membrane-bundling material comprises a synthetic resin that exhibits a hardness retention rate of 95% or more after the material is brought into contact with a saturated water vapor at 121°C for 24 hours. The hollow fiber membrane module (1) can keep substance productivity at a high level and can be used in the production of a chemical substance by a sterilizable continuous fermentation method.
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公开(公告)号：SG172400A1
公开(公告)日：2011-08-29
申请号：SG2011046992
申请日：2009-12-25
Applicant: TORAY INDUSTRIES
Inventor： SAWAI KENJI , SAWAI HIDEKI , MIMITSUKA TAKASHI , ITO MASATERU , YAMADA KATSUSHIGE , KAWAMURA KENJI , MINEGISHI SHIN-ICHI , NAKAGAWA IZUMI , NAGANO TATSUYA
Abstract: Lactic acid obtained by a method for producing lactic acid, the method comprising: (A) a step of continuous fermentation wherein a fermentation culture medium of a microorganism having an ability of lactic acid fermentation is filtered 5 through a porous membrane having an average pore size of not less than 0.01 ttm and less than 1 pm with a transmembrane pressure difference within the range of 0.1 to 20 kPa, and the permeate is collected, while retaining the non-permeated liquid in orreturning the non-permeated liquid to the culture, and adding a fermentation feedstock to the culture: (B) a step of filtering the permeate obtained in Step (A) 10 through a nanofdtration membrane; and (C) a step of distilling the permeate obtained in Step (B) under a pressure of not less than 1 Pa and not more than atmospheric pressure, at 25°C to 200°C to recover lactic acid; comprises only small amounts of impurities, and a polylactic acid obtained using the lactic acid as a raw material has excellent thermal stability, mechanical strength and hue.
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公开(公告)号：AU2009299152A1
公开(公告)日：2010-04-08
申请号：AU2009299152
申请日：2009-09-16
Applicant: TORAY INDUSTRIES
Inventor： MIMITSUKA TAKASHI , ISHII KENTARO , MORITA KEN , HIGASA MASASHI , SAWAI KENJI , SAWAI HIDEKI , YAMADA KATSUSHIGE , MINEGISHI SHINICHI
Abstract: To control flow velocity of a culture liquid inside a membrane separation tank without giving influences to culture conditions in the fermentation tank, and also suppress precipitation of microorganisms or culture cells so that the production efficiency of the chemical product can be improved, in a method for producing a chemical product including the steps of: cultivating microorganisms or culture cells in a fermentation tank; transferring a culture liquid from the fermentation tank to a membrane separation tank so as to filter the culture liquid through a separation membrane; and collecting a fermentation product from a filtration liquid as the chemical product while refluxing an unfiltered culture liquid that has not been filtered so as to be joined to the culture liquid on an upstream side of the membrane separation tank, one portion of the culture liquid to be transferred from the fermentation tank is allowed to bypass the membrane separation tank depending on a pressure at the culture liquid flow-in side of the membrane separation tank.
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公开(公告)号：CA2690492A1
公开(公告)日：2009-01-08
申请号：CA2690492
申请日：2008-06-18
Applicant: TORAY INDUSTRIES
Inventor： ITO MASATERU , MINEGISHI SHIN-ICHI , SHIMIZU ERI , SAWAI KENJI , ITO YOHITO , SAWAI HIDEKI , YAMADA KATSUSHIGE
Abstract: Disclosed is a lactic acid production method by separating lactic acid produced in a culture solution by means of the fermentation culture of a microorganism. Specifically disclosed is a lactic acid production method, which comprises: a step (A) of filtering the culture solution through a nano-filtration membrane; and a step (B) of distilling a lactic-acid-containing solution produced in the step (A) under a pressure ranging from 1 Pa to the atmospheric pressure (inclusive) at a temperature ranging from 25 to 200°C (inclusive) to collect lactic acid. The method can effectively remove an inorganic salt dissolved in a fermentation culture solution or contained in the fermentation culture solution in the form of a poorly soluble solid material by a simple manipulation, enables to prevent the racemization or oligomerization of lactic acid during the process of producing lactic acid, and therefore can produce lactic acid in a high yield.
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