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公开(公告)号：MX2014005564A
公开(公告)日：2014-11-10
申请号：MX2014005564
申请日：2012-11-09
Applicant: UCB PHARMA SA
Inventor： HUMPHREYS DAVID PAUL , ADAMS RALPH , BHATTA PALLAVI , HEYWOOD SAM PHILLIP
Abstract: La invención se refiere a moléculas que son anticuerpos con especificidad por determinantes antigénicos de OX40 humano, a usos terapéuticos de las moléculas que son anticuerpos y a métodos para producir las moléculas que son anticuerpos.
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公开(公告)号：SG11201401649VA
公开(公告)日：2014-07-30
申请号：SG11201401649V
申请日：2012-11-09
Applicant: UCB PHARMA SA
Inventor： ADAMS RALPH , BHATTA PALLAVI , HEYWOOD SAM PHILLIP , HUMPHREYS DAVID PAUL
Abstract: A serum albumin binding antibody or fragment thereof comprising a heavy chain variable domain having the sequence given in SEQ ID NO: 1 or SEQ ID NO:2 and/or comprising a light chain variable domain having the sequence given in SEQ ID NO:3 or SEQ ID NO:4, in particular comprising a heavy chain variable domain and a light chain variable domain having the sequence given in SEQ ID NO: 1 and SEQ ID NO:3 or a heavy chain variable domain and a light chain variable domain having the sequence given in SEQ ID NO: 2 and SEQ ID NO:4. The disclosure also extends to polynucleotides encoding the antibodies or fragments, vectors comprising same and host cells capable of expressing the polynucleotides. The disclosure further includes pharmaceutical compositions comprising the antibodies or fragments and therapeutic used of any one of the same.
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公开(公告)号：SG11201402093RA
公开(公告)日：2014-06-27
申请号：SG11201402093R
申请日：2012-11-09
Applicant: UCB PHARMA SA
Inventor： ADAMS RALPH , BHATTA PALLAVI , HEYWOOD SAM PHILLIP , HUMPHREYS DAVID PAUL
Abstract: The invention relates to antibody molecules having specificity for antigenic determinants of human OX40, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.
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