公开(公告)号：AU2010222693B2

公开(公告)日：2014-12-04

申请号：AU2010222693

申请日：2010-03-10

Applicant: UCB PHARMA SA

Inventor： GOZZARD NEIL ,  LAWSON ALASTAIR DAVID GRIFFITHS ,  LIGHTWOOD DANIEL JOHN ,  PALFRAMAN ROGER THOMAS ,  SMITH BRYAN JOHN ,  TYSON KERRY LOUISE

IPC: C07K16/24 ,  A61K39/395 ,  A61P11/06 ,  C07K16/46 ,  C12N15/13

Abstract: Antibody molecules having specificity for antigenic determinants of human IL-13, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.

公开(公告)号：CA2872326A1

公开(公告)日：2014-02-06

申请号：CA2872326

申请日：2013-05-13

Applicant: UCB PHARMA SA

Inventor： FINNEY HELENE MARGARET ,  LAWSON ALASTAIR DAVID GRIFFITHS ,  SHAW STEVAN GRAHAM ,  SMITH BRYAN JOHN ,  TYSON KERRY LOUISE ,  KEVORKIAN LARA ,  MEIER CHRISTOPH ,  SARKAR KAUSHIK ,  ATHERFOLD PAUL ALAN

IPC: C07K16/28 ,  G01N33/53

Abstract: The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.

公开(公告)号：CA2754539A1

公开(公告)日：2010-09-16

申请号：CA2754539

申请日：2010-03-10

Applicant: UCB PHARMA SA

Inventor： GOZZARD NEIL ,  LAWSON ALASTAIR DAVID GRIFFITHS ,  LIGHTWOOD DANIEL JOHN ,  PALFRAMAN ROGER THOMAS ,  SMITH BRYAN JOHN ,  TYSON KERRY LOUISE

IPC: C07K16/24 ,  A61K39/395 ,  A61P11/06 ,  C07K16/46 ,  C12N15/13

Abstract: Antibody molecules having specificity for antigenic determinants of human IL-13, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.

公开(公告)号：EA032222B1

公开(公告)日：2019-04-30

申请号：EA201101303

申请日：2010-03-10

Applicant: UCB PHARMA SA

Inventor： GOZZARD NEIL ,  LAWSON ALASTAIR DAVID GRIFFITHS ,  LIGHTWOOD DANIEL JOHN ,  PALFRAMAN ROGER THOMAS ,  SMITH BRYAN JOHN ,  TYSON KERRY LOUISE

IPC: C07K16/24 ,  A61K39/395 ,  A61P11/06 ,  C07K16/46 ,  C12N15/13

Abstract: Визобретенииописанымолекулыантител, обладающиеспецифичностьюв отношенииантигенныхдетерминант IL-13 человека, терапевтическиеприменениямолекулантители способыполученияуказанныхмолекулантител.

公开(公告)号：PE00022015A1

公开(公告)日：2015-01-28

申请号：PE0019872014

申请日：2013-05-13

Applicant: UCB PHARMA SA

Inventor： FINNEY HELENE MARGARET ,  LAWSON ALASTAIR DAVID GRIFFITHS ,  SHAW STEVAN GRAHAM ,  SMITH BRYAN JOHN ,  TYSON KERRY LOUISE ,  KEVORKIAN LARA ,  MEIER CHRISTOPH ,  SARKAR KAUSHIK ,  ATHERFOLD PAUL ALAN

IPC: C07K16/28 ,  G01N33/53

CPC classification number: C07K16/283 ,  A61K39/3955 ,  A61K47/60 ,  A61K47/643 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/24 ,  C07K2317/33 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/92 ,  G01N33/5047 ,  G01N33/564 ,  G01N33/6854 ,  G01N33/6857 ,  G01N33/6893 ,  G01N2333/70535 ,  G01N2500/02 ,  G01N2500/10 ,  G01N2800/104 ,  G01N2800/24 ,  G01N2800/28

Abstract: SE REFIERE A UN ANTICUERPO O FRAGMENTO DE UNION DEL MISMO ANTI-FCRN QUE COMPRENDE: UNA CADENA PESADA QUE TIENE UNA REGION VARIABLE QUE COMPRENDE TRES CDR SELECCIONADAS INDEPENDIENTEMENTE DE SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3 ; Y UNA CADENA LIGERA QUE TIENE UNA REGION VARIABLE QUE COMPRENDE TRES CDR SELECCIONADAS INDEPENDIENTEMENTE DE SEQ ID NO:4, SEQ ID NO:5, SEQ ID NO:6. SE REFIERE TAMBIEN A UNA COMPOSICION FARMACEUTICA QUE ES UTIL PARA EL TRATAMIENTO DE ENFERMEDADES AUTOINMUNES.

公开(公告)号：SG11201406625XA

公开(公告)日：2014-12-30

申请号：SG11201406625X

申请日：2013-05-13

Applicant: UCB PHARMA SA

Inventor： FINNEY HELENE MARGARET ,  LAWSON ALASTAIR DAVID GRIFFITHS ,  SHAW STEVAN GRAHAM ,  SMITH BRYAN JOHN ,  TYSON KERRY LOUISE ,  KEVORKIAN LARA ,  MEIER CHRISTOPH ,  SARKAR KAUSHIK ,  ATHERFOLD PAUL ALAN

IPC: G01N33/53 ,  C07K16/28

Abstract: The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.

公开(公告)号：AU2011284551A1

公开(公告)日：2013-01-31

申请号：AU2011284551

申请日：2011-07-28

Applicant: UCB PHARMA SA

Inventor： SMITH BRYAN JOHN ,  KIRKE HELEN MARIE

IPC: G01N33/68

Abstract: A method of measuring acidic species generated by degradation of a Fab or Fab' component of a Fab-PEG or a Fab '-PEG comprising the steps of: a) cleaving the PEG and linker from the Fab-PEG or Fab '-PEG with an enzyme, b) optionally separating the PEG and linker generated in step a) from the Fab or Fab', to provide a Fab or Fab' and c) quantitatively analyzing acidic species associated with the cleaved Fab or Fab' and/or the cleaved PEG.