Abstract:
The disclosed spray deposition systems and methods use spray charging and discharging techniques to assist with digital deposition of spray droplets on a substrate. For example, the disclosed systems and methods have a charging system that generates spray droplets from a spray generator and charges the droplets. Focusing electrodes help to collimate the droplets into a tight droplet stream and, optionally, steering electrodes help direct the tight droplet stream. A charge removal system neutralizes or removes the charge from the droplets, either during the deposition of the droplets on a substrate or after the droplets have been deposited on a substrate.
Abstract:
The invention is directed to devices and methods for electrohydrodynamic (EHD) aerosolization of liquids utilizing a dissociated discharge electrode and an electric field shield disposed between the nozzle and the discharge electrode. Preferred embodiments are designed as inhalers suitable for administration of therapeutic compounds to the respiratory tract of a patient, preferably the lungs.
Abstract:
The invention is directed to devices and methods for electrohydrodynamic (EHD) aerosolization of liquids utilizing a dissociated discharge electrode and an electric field shield disposed between the nozzle and the discharge electrode. Preferred embodiments are designed as inhalers suitable for administration of therapeutic compounds to the respiratory tract of a patient, preferably the lungs.
Abstract:
A method of fabricating deposits of non-volatile substances, including biomacromolecules, in the form of spots and filing on a substrate surface by electrospray, where the deposits are used to determine the interaction of the deposited non-volatile substances to other substances. Also included in this method is the mass fabrication on a single chip of an array of single and multicomponent microsamples.
Abstract:
A system for blowing loose-fill insulation includes a loose-fill blowing machine including a discharge hose. An ionizer is disposed in the flow path of the insulation through the discharge hose, wherein the ionizer reduces the static charge developed on the insulation prior to discharge thereof. A method of reducing static charge developed on loose-fill insulation during blowing is also provided and includes the step of ionizing the insulation in the flow path of the insulation while the insulation is being discharged to reduce the static charge.
Abstract:
A substrate placed on a movable table movable in the X-direction and a spreading nozzle swingable in the Y-direction are relatively moved such that an extended line of the center axis of the spreading nozzle draws a zigzag trace on the substrate. During this relative movement, spacers are spread from the spreading nozzle while the substrate is sequentially discharged by a discharging bar in the moving direction of the substrate by a discharging bar. When the spreading nozzle passes each of folded portions where the trace is folded, the spread amount of the spacers from the spreading nozzle is reduced.
Abstract:
A device for dispensing a liquid for inhalation, which comprises an unshielded electrohydrodynamic comminution means (1), a means for supplying a liquid to the comminution means, a sharp discharge electrode (12) and, optionally, a means for charging the discharge electrode to a polarity opposite to that of the comminution means, wherein the discharge electrode is located so as to direct gaseous ions into the body of the comminuted liquid and thereby to fully or partially discharge the comminuted liquid.
Abstract:
An electrostatic pump in an electrostatic sprayer is disclosed which comprises an ion injection electrode means disposed in a liquid conduit for conveying liquid to a sprayhead, downstream of the ion injection electrode is an ion discharge electrode means comprising an earthed ring, a potential difference is provided between the electrodes to provide hydrostatic pressure for conveying liquid in a conduit to the sprayhead.
Abstract:
Methods of electrospraying particles are disclosed that include electrospraying a liquid spray composition from the nozzle, the liquid spray composition including a liquid and a compound that exhibits a melting point and a crystallization temperature, and at least one of exposing particles formed from the liquid spray composition to a temperature modified environment, exposing particles formed from the liquid spray composition to an organic solvent, and collecting particles formed from the liquid spray composition on at least one of a temperature modified collector, a liquid collector, a variable topography collector, and a dry ice collector.
Abstract:
A device and method for delivering an aerosolized liquid having therapeutic properties to a user's lungs. The compact and convenient device includes a housing of such size that it can be held in a user's one hand with an exit opening in the housing for directing the aerosol to the user's mouth. The housing encloses a dispensing system for containing the liquid to be aerosolized and delivering it to an electrohydrodynamic apparatus and an electrohydrodynamic apparatus for aerosolizing the liquid and delivering the aerosol to the exit opening. The electrohydrodynamic apparatus produces a cloud of aerosolized liquid droplets having a monodispersed reparable droplet size and near zero velocity. The aerosolizing apparatus includes a plurality of spray sites each having a tip end, the spray sites cooperating with a charge source to result in an aerosolized spray from at least one tip end, a plurality of discharge electrodes downstream of the tip ends, and a plurality of reference electrodes downstream of the plurality of discharge electrodes.