公开(公告)号：US11754496B2

公开(公告)日：2023-09-12

申请号：US17449715

申请日：2021-10-01

Applicant: MLS ACQ, Inc.

Inventor： Martin L. Spartz ,  Anthony S. Bonanno ,  Kelly Renee McPartland

IPC: G01B9/02 ,  G01N21/3518 ,  G01N33/00 ,  G01N21/35

CPC classification number: G01N21/3518 ,  G01N33/0044 ,  G01N2021/3595 ,  G01N2201/1247

Abstract: A gas analysis system with an FTIR spectrometer preferably utilizes a long path gas cell, a narrow band detector, and an optical filter that narrows the detection region to measure hydrogen sulfide.

公开(公告)号：US20170062288A1

公开(公告)日：2017-03-02

申请号：US15205069

申请日：2016-07-08

Applicant: Renesas Electronics Corporation

Inventor： Toshikazu HANAWA ,  Kazuhide FUKAYA ,  Kentaro YAMADA

IPC: H01L21/66 ,  H01L21/768 ,  G01N21/84 ,  H01L23/532 ,  G01N21/73 ,  H01L21/311 ,  H01L23/522

CPC classification number: H01L22/26 ,  G01N21/68 ,  G01N21/73 ,  G01N21/84 ,  G01N2021/8411 ,  G01N2021/8427 ,  G01N2201/1247 ,  H01J37/32963 ,  H01J2237/334 ,  H01L21/31116 ,  H01L21/76802 ,  H01L21/76846 ,  H01L21/76877 ,  H01L23/5226 ,  H01L23/53223 ,  H01L23/53266 ,  H01L23/5329

Abstract: A via hole is accurately formed in an interlayer insulating film over a metal wiring. Of emission spectra of plasma to be used for dry etching of the interlayer insulating film, the emission intensities of at least CO, CN, and AlF are monitored such that an end point of the dry etching of the interlayer insulating film is detected based on the emission intensities thereof.

Abstract translation: 在金属布线上的层间绝缘膜中精确地形成通孔。 对于用于层间绝缘膜的干式蚀刻的等离子体的发射光谱，至少监测CO，CN和AlF的发射强度，使得基于层间绝缘膜的干蚀刻的终点被检测 发射强度。

公开(公告)号：US09562851B2

公开(公告)日：2017-02-07

申请号：US14648874

申请日：2013-12-04

Applicant: SP3H

Inventor： Sylvain Oberti ,  Johan Fournel

IPC: G01N21/3577 ,  G01N21/3504 ,  G01N21/27 ,  G01N21/31

CPC classification number: G01N21/3577 ,  G01N21/274 ,  G01N21/3504 ,  G01N2021/3181 ,  G01N2201/062 ,  G01N2201/0624 ,  G01N2201/121 ,  G01N2201/1211 ,  G01N2201/124 ,  G01N2201/1242 ,  G01N2201/1247 ,  G01N2201/127 ,  G01N2201/12723

Abstract: The present invention relates to a method for controlling a spectrometer for analyzing a product, the spectrometer including a light source including several light-emitting diodes having respective emission spectra covering in combination an analysis wavelength band, the method including steps of: supplying at least one of the light-emitting diodes with a supply current to switch it on, measuring a light intensity emitted by the light source by measuring a current at a terminal of at least another of the light-emitting diodes maintained off, determining, according to each light intensity measurement, a setpoint value of the supply current of each diode that is on, and regulating the supply current of each diode that is on so that it corresponds to the setpoint value.

Abstract translation: 本发明涉及一种用于分析产品的光谱仪的控制方法，该光谱仪包括具有多个发光二极管的光源，该发光二极管具有组合分析波长带的各发射光谱，该方法包括以下步骤：将至少一个 的发光二极管与供电电流接通，通过测量至少另一个发光二极管的端子上的电流来测量由光源发射的光强度，根据每个光 强度测量，导通的每个二极管的电源电流的设定值，以及调节导通的每个二极管的电源电流，使其对应于设定值。

公开(公告)号：US20140140607A1

公开(公告)日：2014-05-22

申请号：US14233002

申请日：2012-07-27

Applicant: Jonas Erjefält

Inventor： Jonas Erjefält

IPC: G06K9/00 ,  G06T7/00

CPC classification number: G06K9/00147 ,  G01N1/30 ,  G01N21/4795 ,  G01N21/77 ,  G01N21/78 ,  G01N33/5005 ,  G01N2021/7786 ,  G01N2201/1247 ,  G06K9/0014 ,  G06T7/0012

Abstract: A method for differentiating areas in a series of digital images, the method comprising the steps of: providing a series of images comprising undetermined marker areas; evaluating every image 1n for 1≦n≦N according to predetermined selection criteria and defining image marker areas as undetermined marker areas fulfilling the predetermined selection criteria; providing a new image 1new; and inserting new image marker areas in the new image 1new, said new image marker areas having the same shape and location as image marker areas present in image 1n but not in image 1n−1, and said new image marker areas being identifiable in 1new by a unique feature. Further, the application discloses a method for visualizing cell populations in tissue sections of a histological sample. Further, the application discloses a method for visualizing three-dimensional distribution of multiple cell populations in a histological sample.

Abstract translation: 一种用于区分一系列数字图像中的区域的方法，所述方法包括以下步骤：提供包括未确定标记区域的一系列图像; 根据预定的选择标准评估每个图像1n为1＆nlE; n＆nlE; N，并将图像标记区域定义为满足预定选择标准的未确定标记区域; 提供新的图像1新; 并在新图像1中插入新的图像标记区域，所述新图像标记区域具有与图像1n中但不在图像1n-1中存在的图像标记区域相同的形状和位置，并且所述新图像标记区域可以通过 一个独特的功能。 此外，该申请公开了一种在组织学样品的组织切片中可视化细胞群的方法。 此外，本申请公开了一种用于在组织学样本中可视化多个细胞群体的三维分布的方法。

公开(公告)号：US08248586B2

公开(公告)日：2012-08-21

申请号：US12427280

申请日：2009-04-21

Applicant: Mamoru Tomita

Inventor： Mamoru Tomita

IPC: G01N33/48 ,  G01N21/00 ,  G01B11/00 ,  G01B11/14

CPC classification number: G01N21/07 ,  G01N21/59 ,  G01N35/00584 ,  G01N35/025 ,  G01N2035/00148 ,  G01N2201/0415 ,  G01N2201/0446 ,  G01N2201/1247

Abstract: A blood analysis apparatus is provided. The blood analysis apparatus includes: a chip holding portion having an aperture which allows light to pass therethrough and holding a μ-TAS chip for holding a measurement liquid; a rotary body on which the chip holding portion is mounted; a light source; and a light-receiving unit. A measurement position of the rotary body at which the measurement liquid is to be measured with the light from the light source is set by: rotating the rotary body to obtain a light value of light which is emitted from the light source and received by the light-receiving unit through the aperture; and setting a rotational position of the rotary body where the light value is a threshold value or more, as the measurement position.

Abstract translation: 提供血液分析装置。 血液分析装置包括：芯片保持部，具有允许光通过的孔，并保持用于保持测量液体的μ-TAS芯片; 旋转体，其上安装有芯片保持部; 光源; 和光接收单元。 利用来自光源的光来测量测量液体的旋转体的测量位置是通过旋转旋转体来获得从光源发射并被光接收的光的光值 - 接收单元通过孔径; 并且将光值为阈值以上的旋转体的旋转位置设定为测量位置。

公开(公告)号：JP2016501372A

公开(公告)日：2016-01-18

申请号：JP2015546080

申请日：2013-12-04

Applicant: エスピースリーエイチ

Inventor： オベルティ，シルヴァイン ,  フォーネル，ヨハン

IPC: G01N21/27 ,  G01N21/3504 ,  G01N21/359

CPC classification number: G01N21/3577 ,  G01N21/274 ,  G01N21/3504 ,  G01N2021/3181 ,  G01N2201/062 ,  G01N2201/0624 ,  G01N2201/121 ,  G01N2201/1211 ,  G01N2201/124 ,  G01N2201/1242 ,  G01N2201/1247 ,  G01N2201/127 ,  G01N2201/12723

Abstract: 本発明は、製品を分析するための分光計の制御方法に関し、方法は、光源(LS)の動作を表す測定値(LFL、TPL)を取得するステップと、測定値に応じて、光源の供給電流(LCx)の値、および/または光源によって放出され、分析対象製品と相互作用した光線(LB)の経路上に配置されるセンサ(OPS)の感光セル(y)の積分時間(ITy)の値を決定するステップとを含み、さらに積分時間および/または供給電流値が閾値の間にある場合、光源に決定された供給電流値に対応する供給電流を供給するステップと、感光セルの積分時間を決定された積分時間の値に調整するステップと、スペクトルが形成され得るように、センサによって供給される光強度測定値(MSy)を取得するステップとを含む。【選択図】図1

Abstract translation: 本发明涉及一种光谱仪的控制方法，用于分析表示（LS）（LFL，TPL）获取，在根据所测量的值的操作的产品，方法，来源测量，光源的供给 电流通过的（LCX）的值和/或所述光源发射的，所述分析物的产品与传感器（OPS），其设置的积分时间（LB）（y）的路径上的光敏感的细胞相互作用（）Ity的 和确定的值时，如果进一步的积分时间和/或供给电流值是阈值，并提供对应于所述光源，感光细胞的积分时间决定的供给电流值的电源电流之间 和调节的积分时间的值被确定为使得能够形成的光谱，获得由传感器（MSY）提供的光强度测量的步骤。 点域1

公开(公告)号：JP2009536727A

公开(公告)日：2009-10-15

申请号：JP2009504277

申请日：2007-04-04

Applicant: シングレックス,インコーポレイテッド

Inventor： ゴイックス，フィリッペ ,  トッド，ジョン ,  プスカシュ，ロバート ,  ヘルド，ダグラス ,  リビングストン，リチャード

IPC: G01N21/78 ,  G01N21/64 ,  G01N33/483 ,  G01N33/53 ,  G01N33/68

CPC classification number: G01N33/6887 ,  G01N15/06 ,  G01N15/1459 ,  G01N21/6428 ,  G01N33/577 ,  G01N33/582 ,  G01N2015/0693 ,  G01N2015/1006 ,  G01N2015/1486 ,  G01N2201/1247 ,  G01N2201/12761 ,  G01N2800/32 ,  G01N2800/324 ,  G01N2800/52 ,  Y10T436/105831

Abstract: 分子の高感度検出のための方法、キット、および組成物を開示する。 これらの方法、キット、および組成物は、試料中の分子の濃度を１フェムトモル、１アトモル、またはそれ以下のレベルまで決定する際に有用である。 これらの方法、キット、および組成物は、試料の希釈を必要としないで、広範囲、例えば７ｌｏｇの範囲にわたる濃度の決定も可能にする。

公开(公告)号：US09977031B2

公开(公告)日：2018-05-22

申请号：US15348120

申请日：2016-11-10

Applicant: Singulex, Inc. ,  The Regents of the University of California

Inventor： Philippe Goix ,  Robert Puskas ,  John Todd ,  Richard Livingston ,  Douglas Held ,  Allan H. B. Wu

IPC: G01N33/58 ,  G01N33/68 ,  G01N33/577

CPC classification number: G01N33/6887 ,  G01N15/06 ,  G01N15/1459 ,  G01N21/6428 ,  G01N33/577 ,  G01N33/582 ,  G01N2015/0693 ,  G01N2015/1006 ,  G01N2015/1486 ,  G01N2201/1247 ,  G01N2201/12761 ,  G01N2800/32 ,  G01N2800/324 ,  G01N2800/52 ,  Y10T436/105831

Abstract: The invention provides methods, compositions, kits, and systems for the sensitive detection of cardiac troponin, Such methods, compositions, kits, and systems are useful in diagnosis, prognosis, and determination of methods of treatment in conditions that involve release of cardiac troponin.

公开(公告)号：US20180106717A1

公开(公告)日：2018-04-19

申请号：US15715761

申请日：2017-09-26

Applicant: Government of the United States of America, as represented by the Secretary of Commerce

Inventor： SAMUEL MARTIN STAVIS ,  CRAIG ROBERT COPELAND

IPC: G01N21/31 ,  C12N15/10 ,  G02B21/36 ,  G01N1/30 ,  G01N21/64 ,  G01N21/89 ,  C12Q1/6825

CPC classification number: G01N21/314 ,  C12N15/1006 ,  C12Q1/68 ,  C12Q1/6825 ,  G01N1/30 ,  G01N21/6428 ,  G01N21/6458 ,  G01N21/8903 ,  G01N2021/174 ,  G01N2021/3129 ,  G01N2021/3196 ,  G01N2021/556 ,  G01N2021/558 ,  G01N2021/6419 ,  G01N2021/6441 ,  G01N2021/6491 ,  G01N2021/7756 ,  G01N2021/8883 ,  G01N2201/1247 ,  G02B21/361 ,  G02B21/367 ,  C12Q2525/204 ,  C12Q2563/107 ,  C12Q2565/601

Abstract: A process for measuring a size distribution of a plurality of nucleic acid molecules, the process comprising: labeling the nucleic acid molecules with a fluorescent dye comprising a plurality of fluorescent dye molecules to form labeled nucleic acid molecules, such that a number of fluorescent dyes molecules attached to each nucleic acid molecule is reliably proportional to the number of base pairs in the nucleic acid molecule, the fluorescent dye molecules having a first florescence spectrum; producing, by the labeled nucleic acid molecules, the first florescence spectrum in response to irradiating the labeled nucleic acid molecules at the first wavelength; and detecting the first florescence spectrum to measure the size distribution of the plurality of nucleic acid molecules.

公开(公告)号：US20170153248A1

公开(公告)日：2017-06-01

申请号：US15348120

申请日：2016-11-10

Applicant: Singulex, Inc. ,  The Regents of the University of California

Inventor： Philippe Goix ,  Robert Puskas ,  John Todd ,  Richard Livingston ,  Douglas Held ,  Allan H.B. Wu

IPC: G01N33/68 ,  G01N33/577 ,  G01N33/58

CPC classification number: G01N33/6887 ,  G01N15/06 ,  G01N15/1459 ,  G01N21/6428 ,  G01N33/577 ,  G01N33/582 ,  G01N2015/0693 ,  G01N2015/1006 ,  G01N2015/1486 ,  G01N2201/1247 ,  G01N2201/12761 ,  G01N2800/32 ,  G01N2800/324 ,  G01N2800/52 ,  Y10T436/105831

Abstract: The invention provides methods, compositions, kits, and systems for the sensitive detection of cardiac troponin, Such methods, compositions, kits, and systems are useful in diagnosis, prognosis, and determination of methods of treatment in conditions that involve release of cardiac troponin.