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    AUTOMATIC EVOLUTION OF MIXED ANALOG AND DIGITAL ELECTRONIC CIRCUITS
    293.
    发明申请
    AUTOMATIC EVOLUTION OF MIXED ANALOG AND DIGITAL ELECTRONIC CIRCUITS 审中-公开
    混合模拟和数字电子电路的自动演进

    公开(公告)号：WO0019369A8

    公开(公告)日：2000-07-13

    申请号：PCT/US9922917

    申请日：1999-10-01

    Applicant: BIOS GROUP LP ,  HERRIOT JAMES W ,  KAUFFMAN STUART A

    Inventor： HERRIOT JAMES W ,  KAUFFMAN STUART A

    IPC: G06N3/00 ,  G06F15/00 ,  G06F15/18

    CPC classification number: G06N3/004

    Abstract: A method and system for evolving electronic circuits based on defined rules. A first approach uses a network (50) of nodes (60) having established topological and behavioral relationships amongst themselves. A second approach employs software agents to create signal filters. The software agents are allowed to evolve in signal parameter space so as to match a reference signal (200), subject to established evolutionary rules and parameter space constraints. Narrowband and a low-pass filter can be formed using such agents.

    Abstract translation: 基于定义规则演进电子电路的方法和系统。 第一种方法使用其间具有已建立的拓扑和行为关系的节点（60）的网络（50）。 第二种方法使用软件代理来创建信号过滤器。 允许软件代理在信号参数空间中进化，以便匹配参考信号（200），受制于进化规则和参数空间限制。 可以使用这样的试剂形成窄带和低通滤波器。

    A METHOD FOR OPTIMAL SEARCH ON A TECHNOLOGY LANDSCAPE
    294.
    发明申请
    A METHOD FOR OPTIMAL SEARCH ON A TECHNOLOGY LANDSCAPE 审中-公开
    一种对技术景观进行最佳搜索的方法

    公开(公告)号：WO0013072A3

    公开(公告)日：2000-06-29

    申请号：PCT/US9919916

    申请日：1999-08-31

    Applicant: BIOS GROUP LP ,  KAUFFMAN STUART A ,  LOBO JOSE ,  MACREADY WILLIAM G

    Inventor： KAUFFMAN STUART A ,  LOBO JOSE ,  MACREADY WILLIAM G

    IPC: G06F17/10 ,  G06Q10/00 ,  G06F9/455 ,  G06F17/11 ,  G06F17/50

    CPC classification number: G06Q10/04 ,  G06Q30/0283

    Abstract: Technological change at the film-level has commonly been modeled as random sampling from a fixed distribution of possibilities. Such models, however, typically ignore empirically important aspects of the firm's search process, notably the observation that the present state of the firm guides future innovation. We explicitly treat this aspect of the firm's search for technological improvements by introducing a "technology landscape" (Fig. 6) into an otherwise standard dynamic programming setting where the optimal strategy is to assign a reservation price to each possible technology. Search is modeled as movement, constrained by the cost of innovation, over the technology landscape. Simulations (Fig. 6) are presented on a stylized technology landscape while analytic results are derived using landscapes that are similar to Markov random fields.

    Abstract translation: 电影级别的技术变革通常被模拟为从固定分配可能性的随机抽样。 然而，这种模式通常忽略了企业搜索过程的实证重要方面，特别是对企业目前状况指导未来创新的观察。 我们通过将“技术环境”（图6）引入到其他标准的动态规划设置中，明确地对待公司寻求技术改进的方面，其中最佳策略是为每个可能的技术分配预留价格。 搜索被建模为运动，受创新成本的限制，超过了技术格局。 模拟（图6）呈现在风格化的技术景观上，而分析结果是使用与马尔可夫随机场相似的景观得出的。

    IceA GENE AND RELATED METHODS
    295.
    发明申请
    IceA GENE AND RELATED METHODS 审中-公开
    IceA基因及相关方法

    公开(公告)号：WO1997043901A1

    公开(公告)日：1997-11-27

    申请号：PCT/US1997008558

    申请日：1997-05-20

    Applicant: VANDERBILT UNIVERSITY ,  MILLER, Geraldine, G. ,  PEEK, Richard, M., Jr. ,  THOMPSON, Stuart, A. ,  BLASER, Martin, J.

    Inventor： VANDERBILT UNIVERSITY

    IPC: A01N43/04

    CPC classification number: C07K14/205 ,  A61K38/00 ,  A61K39/00

    Abstract: A purified IceA protein of Helicobacter pylori is provided. The protein is expressed as either an IceA 1 or an IceA 2 variant. A purified polypeptide fragment of the IceA protein is also provided. An antigenic fragment of IceA is provided. An isolated nucleic acid that encodes an IceA protein of H. pylori is provided. A nucleic acid that encodes an IceA 1 variant and a nucleic acid that encodes an IceA 2 variant is also provided. Fragments of the IceA gene are provided. A method of detecting the presence of an antibody against H. pylori in a sample is provided. The method comprises the following steps: a) contacting the sample with a purified IceA protein of H. pylori or a H. pylori-specific fragment thereof; and b) detecting the binding of the antibody in the sample to the protein or fragment, the detection of biding indicating the presence in the sample of antibodies against H. pylori. A method of detecting the presence of an antibody against an ulcerative Helicobacter pylori strain in a sample is also provided.

    Abstract translation: 提供幽门螺杆菌纯化的IceA蛋白。 蛋白质表达为IceA 1或IceA 2变体。 还提供了IceA蛋白的纯化多肽片段。 提供了IceA的抗原片段。 提供编码幽门螺杆菌的IceA蛋白的分离的核酸。 还提供了编码IceA 1变体的核酸和编码IceA 2变体的核酸。 提供了IceA基因的片段。 提供了检测样品中幽门螺杆菌抗体的存在的方法。 该方法包括以下步骤：a）将样品与幽门螺杆菌的纯化IceA蛋白或幽门螺杆菌特异性片段接触; 和b）检测样品中的抗体与蛋白质或片段的结合，检测指示在幽门螺杆菌抗体样品中的存在。 还提供了检测样品中针对溃疡性幽门螺杆菌菌株的抗体存在的方法。

    POLYDEXTROSE AND FOOD ADDITIVE MIXTURE
    296.
    发明申请
    POLYDEXTROSE AND FOOD ADDITIVE MIXTURE 审中-公开
    多糖和食品添加剂混合物

    公开(公告)号：WO1996000509A1

    公开(公告)日：1996-01-11

    申请号：PCT/IB1995000376

    申请日：1995-05-18

    Applicant: PFIZER INC. ,  ANDERSON, James, M. ,  CRAIG, Stuart, A., S. ,  MACRI, Christopher, A.

    Inventor： PFIZER INC.

    IPC: A23L01/308

    CPC classification number: A23J3/16 ,  A23J3/04 ,  A23J3/06 ,  A23J3/08 ,  A23J3/10 ,  A23L29/238 ,  A23L29/25 ,  A23L29/256 ,  A23L29/27 ,  A23L29/272 ,  A23L29/284 ,  A23L33/26

    Abstract: A mixture of polydextrose and a food additive is claimed, the said mixture comprising: a solid, highly homogeneous, micro dispersed mixture comprising 70 to 99.99 % polydextrose and 0.01 to 30 % of a food additive capable of significantly improving the moisture absorption and mouthfeel characteristics of polydextrose, wherein said food additive is a polysaccharide, protein, hydrolyzed protein, alkali metal bicarbonate, water-soluble emulsifier, water-disbursable emulsifier or shellac. A method to produce such a mixture is to co-evaporate from water or alcohol the composition described.

    Abstract translation: 要求保护的是聚右旋糖和食品添加剂的混合物，所述混合物包括：固体，高度均匀的微分散混合物，其包含70至99.99％的聚右旋糖和0.01至30％的能够显着改善吸湿性和口感特性的食品添加剂 的聚右旋糖，其中所述食品添加剂是多糖，蛋白质，水解蛋白质，碱金属碳酸氢盐，水溶性乳化剂，水可分散的乳化剂或虫胶。 制备这种混合物的方法是从所述组合物的水或醇共蒸发。

    cDNA CLONING OF POTENTIALLY TRANSFORMING HUMAN ras-RELATED ONCOGENES
    297.
    发明申请
    cDNA CLONING OF POTENTIALLY TRANSFORMING HUMAN ras-RELATED ONCOGENES 审中-公开
    可能转化人类ras相关肿瘤的cDNA克隆

    公开(公告)号：WO1995032223A1

    公开(公告)日：1995-11-30

    申请号：PCT/US1995006420

    申请日：1995-05-24

    Applicant: THE GOVERNMENT OF THE UNITED STATES OF AMERICA, represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES ,  AARONSON, Stuart, A.

    Inventor： THE GOVERNMENT OF THE UNITED STATES OF AMERICA, represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES ,  CHAN, Andrew ,  MIKI, Toru

    IPC: C07K14/82

    CPC classification number: C07K14/82 ,  C12Q1/6886 ,  C12Q2600/156

    Abstract: The oncogene of the present invention, isolated by expression cloning from a human ovarian cancer is a mutant of TC21. The present invention teaches that ras-related genes not thought to have transforming potential can contribute importantly to cancers which have been refractory to oncogene detection. The present invention teaches that another ras relative gene, R-ras, which was previously reported to lack transforming potential, has transforming capacity as well. Thus, these and other genes similarly related to prototype and activated by analogous mechanisms may be important in the diagnosis and prognosis of certain cancers, as well as be critical in the design of rational approaches to therapy of cancers in which they play a role.

    Abstract translation: 通过从人卵巢癌的表达克隆分离的本发明的致癌基因是TC21的突变体。 本发明教导了未被认为具有转化潜力的ras相关基因可以重要地对致癌基因检测难治的癌症起重要作用。 本发明教导了另一种ras相对基因R-ras，其先前报道为缺乏转化潜力，也具有转化能力。 因此，与原型相似的这些和其他基因和通过类似机制激活的基因在某些癌症的诊断和预后中可能是重要的，并且对于其中起作用的癌症的治疗的理性方法的设计至关重要。

    VISION APPARATUS
    298.
    发明申请
    VISION APPARATUS 审中-公开
    视觉设备

    公开(公告)号：WO1993019429A1

    公开(公告)日：1993-09-30

    申请号：PCT/AU1993000111

    申请日：1993-03-18

    Applicant: ICONIX PTY. LTD. ,  CIOLLI, Robert ,  McCORMACK, Stuart, A. ,  HITCHENS, Denis, C.

    Inventor： ICONIX PTY. LTD.

    IPC: G06F15/70

    CPC classification number: G08G1/04 ,  G01P3/68 ,  G06T7/20 ,  G08G1/015

    Abstract: Vision apparatus is disclosed which comprises at least one single-line scan type line scan camera (30, 40) mounted for viewing a passing object (60, 150). The cameras (30, 40) are connected with electronic means (50) which includes store means (53) which stores signals indicative of the image of the object throughout line scans. The electronic means (50) includes processing means (52) whhich processes the signals indicative of the image of the object together with a signal representative of at least one of the speed or length of the object to determine a length of the object between line scans. That determined length between line scans is provided to image recognition means (100) and utilized with signals in the store means (53) and compared against expected image signature or image attribute signals for recognition. If there is recognition an output is provided representative of a recognised image signature or image attribute. Preferably two cameras (30, 40) are utilized so that one views the object (60, 150) at a different position along its path of travel and where a signal representative of the speed of the object is obtained by comparing particular time instants when a part of the object is detected by each camera.

    Abstract translation: 公开了一种视觉设备，其包括安装用于观看通过物体（60,150）的至少一个单行扫描型行扫描照相机（30,40）。 相机（30,40）与电子装置（50）相连，电子装置（50）包括存储装置（53），存储装置（53）在线扫描中存储指示对象图像的信号。 电子装置（50）包括处理装置（52），其处理指示对象的图像的信号以及表示对象的速度或长度中的至少一个的信号，以确定在线扫描之间的物体的长度 。 将行扫描之间的确定长度提供给图像识别装置（100），并与存储装置（53）中的信号一起使用，并与预期图像签名或图像属性信号进行比较以进行识别。 如果存在识别，则提供表示识别的图像签名或图像属性的输出。 优选地，使用两个照相机（30,40），使得其在沿其行进路径的不同位置处观察物体（60,150），并且其中通过比较特定时刻来获得表示物体的速度的信号 物体的一部分被每个摄像机检测到。

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