公开(公告)号：US20120019819A1

公开(公告)日：2012-01-26

申请号：US13145711

申请日：2010-01-20

Applicant: Robert G. Messerchmidt

Inventor： Robert G. Messerchmidt

IPC: G01J3/44 ,  G01J3/45 ,  G01J3/28 ,  G06F15/16

CPC classification number: G01J3/44 ,  G01J3/433 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/106

Abstract: Raman spectroscopy apparatuses are described that detect the spectral characteristics of a sample wherein the apparatus consists of a multiplicity of modulated discrete light sources adapted to excite a sample with electromagnetic radiation, a filter adapted to isolate a predetermined wavelength emitted by the sample wherein the wavelength is further modulated at different frequencies, and a detector for detecting the isolated wavelength. The apparatus may further consist of an interferometer, such as a Michelson interferometer, adapted to modulate the excitation energy. Also provided herein are methods, systems, and kits incorporating the Raman spectroscopy apparatus.

Abstract translation: 描述了拉曼光谱装置，其检测样品的光谱特性，其中该装置由适于用电磁辐射激发样品的多个调制离散光源组成，适用于隔离由样品发射的预定波长的滤波器，其中波长为 在不同频率进一步调制，以及用于检测孤立波长的检测器。 该装置还可以包括适于调制激发能的干涉仪，例如迈克尔逊干涉仪。 本文还提供了结合拉曼光谱仪的方法，系统和试剂盒。

公开(公告)号：US07760342B2

公开(公告)日：2010-07-20

申请号：US11963123

申请日：2007-12-21

Applicant: Martin Thomas Zanni ,  Niels H. Damrauer

Inventor： Martin Thomas Zanni ,  Niels H. Damrauer

IPC: G01J3/00

CPC classification number: G01J3/10 ,  G01J3/433

Abstract: A multidimensional spectrometer for the infrared, visible, and ultraviolet regions of the electromagnetic spectrum, and a method for making multidimensional spectroscopic measurements in the infrared, visible, and ultraviolet regions of the electromagnetic spectrum. The multidimensional spectrometer facilitates measurements of inter- and intra-molecular interactions.

Abstract translation: 用于电磁光谱的红外，可见和紫外区域的多维光谱仪，以及用于在电磁光谱的红外线，可见光和紫外区域进行多维光谱测量的方法。 多维光谱仪有助于测量分子间和分子间的相互作用。

公开(公告)号：US07692789B1

公开(公告)日：2010-04-06

申请号：US11734948

申请日：2007-04-13

Applicant: Michael H. Ebinger ,  Ronny D. Harris

Inventor： Michael H. Ebinger ,  Ronny D. Harris

IPC: G01J3/30

CPC classification number: G01J3/433 ,  G01J3/02 ,  G01J3/0218 ,  G01N21/718 ,  G01N2201/08

Abstract: The invention is a system and method of detecting a concentration of an element in a soil sample wherein an opening or slot is formed in a container that supports a soil sample that was extracted from the ground whereupon at least a length of the soil sample is exposed via the opening. At each of a plurality of points along the exposed length thereof, the soil sample is ablated whereupon a plasma is formed that emits light characteristic of the elemental composition of the ablated soil sample. Each instance of emitted light is separated according to its wavelength and for at least one of the wavelengths a corresponding data value related to the intensity of the light is determined. As a function of each data value a concentration of an element at the corresponding point along the length of the soil core sample is determined.

Abstract translation: 本发明是一种检测土壤样品中元素浓度的系统和方法，其中在容器中形成开口或槽，所述容器支撑从地面提取的土壤样品，因此土壤样品的至少一段长度暴露 通过开口。 在沿其暴露长度的多个点中的每一个点处，土壤样品被烧蚀，由此形成等离子体，其发射消融的土壤样品的元素组成的特征。 发射光的每个实例根据其波长被分离，并且对于至少一个波长，确定与光的强度相关的相应数据值。 作为每个数据值的函数，确定沿着土壤样品长度的对应点处元素的浓度。

公开(公告)号：US20100041969A1

公开(公告)日：2010-02-18

申请号：US12450189

申请日：2008-03-16

Applicant: Reinhard D. Beise

Inventor： Reinhard D. Beise

IPC: A61B5/1455 ,  G01N21/35

CPC classification number: G01N21/314 ,  A61B5/14532 ,  A61B5/1455 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0256 ,  G01J3/42 ,  G01J3/433 ,  G01N21/35 ,  G01N21/39 ,  G01N2021/399 ,  G01N2201/0612 ,  G01N2201/0691

Abstract: The invention relates to a measuring device for optically determining the concentration of blood sugar and/or lactate in biological systems, comprising at least one IR radiation source, that radiates IR light on a volume that is to examined, and at least one measuring detector that detects light coming from the volume that is to be examined in order to determine the concentration of blood sugar and/or lactate, also by laymen in a simple manner and anywhere. According to the invention, the IR light radiated on the volume that is to be examined is supplied, prior to entry into the volume, to a reference detector.

Abstract translation: 本发明涉及一种用于光学确定生物系统中血糖和/或乳酸浓度的测量装置，其包括在要检查的体积上辐射IR光的至少一个IR辐射源和至少一个测量检测器 检测来自待检查体积的光，以便通过简单的方式和任何地方的外行来确定血糖和/或乳酸盐的浓度。 根据本发明，辐射在待检查体积上的IR光在进入体积之前被提供给参考检测器。

公开(公告)号：US07662634B2

公开(公告)日：2010-02-16

申请号：US10845727

申请日：2004-05-14

Applicant: Jochen Mahrenholtz ,  Andrea Wimschneider ,  Hans-Georg Pirkl ,  Heinz-Herbert Müller ,  Stefan Dresely ,  Jeffrey Bolton ,  Martin Schiffhauer ,  Udo Wolf ,  Johannes Schweer ,  Martin Gerlach

Inventor： Jochen Mahrenholtz ,  Andrea Wimschneider ,  Hans-Georg Pirkl ,  Heinz-Herbert Müller ,  Stefan Dresely ,  Jeffrey Bolton ,  Martin Schiffhauer ,  Udo Wolf ,  Johannes Schweer ,  Martin Gerlach

IPC: G01N33/00

CPC classification number: G01N21/359 ,  G01J3/433 ,  G01N21/3577 ,  G01N21/65 ,  G01N2021/8416 ,  G01N2201/1293 ,  Y10T436/12 ,  Y10T436/17 ,  Y10T436/172307

Abstract: The invention relates to a method for determining the isomer composition in an isocyanate isomer mixture, wherein a spectrum of the isomer mixture is recorded and the spectrum is entered into a chemometric calibration model.

Abstract translation: 本发明涉及一种用于测定异氰酸酯异构体混合物中的异构体组合物的方法，其中记录异构体混合物的光谱，并将光谱输入到化学计量校准模型中。

公开(公告)号：US07582882B2

公开(公告)日：2009-09-01

申请号：US11184407

申请日：2005-07-19

Applicant: David McLoskey ,  Glenn Baker ,  Jim Mattheis ,  Sal Atzeni

Inventor： David McLoskey ,  Glenn Baker ,  Jim Mattheis ,  Sal Atzeni

IPC: G01N21/62 ,  G01N21/64

CPC classification number: G01N21/6408 ,  G01J3/10 ,  G01J3/433 ,  G01J3/4406 ,  G01N21/6458

Abstract: A method of spectrographic measurement is disclosed. The method generates light energy using a solid state low capacitance excitation source, the light energy being caused to fall on a sample to be assayed, causing the sample to output an output optical signal. The method generates a plurality of modulation frequencies, and a plurality of heterodyne frequencies to form a set of heterodyne signals at the heterodyne frequencies. Each of the heterodyne frequencies is associated with one of the modulation frequencies. Coupling the modulation frequencies to the excitation source, causes the excitation source to generate excitation energy modulated in intensity in proportion to the modulation frequencies. A sampling a portion of the substantially incoherent excitation energy forms a reference substantially incoherent excitation signal.Focusing the output optical signal as an image modulated with the plurality of modulation frequencies on an image intensifier enables the formation of an intensified image modulated with the plurality of modulation frequencies, receiving the intensified image modulated with the plurality of modulation frequencies on a multielement optical detector.

Abstract translation: 公开了一种光谱测量方法。 该方法使用固态低电容激励源产生光能，导致光能落在要测定的样品上，导致样品输出输出光信号。 该方法产生多个调制频率和多个外差频率，以在外差频率上形成一组外差信号。 每个外差频率与调制频率之一相关联。 将调制频率耦合到激励源，使得激发源产生与调制频率成比例的强度调制的激发能。 对基本上非相干激发能量的一部分进行取样，形成参考基本非相干激发信号。 将输出光信号聚焦成图像增强器上用多个调制频率调制的图像，能够形成用多个调制频率调制的增强图像，在多元素光学检测器上接收由多个调制频率调制的增强图像 。

公开(公告)号：US20090116009A1

公开(公告)日：2009-05-07

申请号：US12147842

申请日：2008-06-27

Applicant: Keith A. Nelson ,  Kenan Gundogdu ,  Katherine W. Stone ,  Daniel B. Turner

Inventor： Keith A. Nelson ,  Kenan Gundogdu ,  Katherine W. Stone ,  Daniel B. Turner

IPC: G01J3/12 ,  G02F1/01

CPC classification number: G01J3/433 ,  G01J3/02 ,  G01J3/0224 ,  G01J2003/1286 ,  G02F2203/18 ,  G02F2203/26

Abstract: Methods and apparatusare disclosed, and include: (a) separating an input electromagnetic waveform into a plurality of intermediate waveforms, each of the intermediate waveforms being spatially separated from one another; (b) dispersing frequency components of each intermediate waveform onto different regions of a spatial light modulator and modulating at least some of the dispersed frequency components with the spatial light modulator; and (c) recombining the dispersed frequency components for each of the intermediate waveforms to produce a plurality of temporally shaped output waveforms.

Abstract translation: 公开的方法和装置，包括：（a）将输入电磁波分离为多个中间波形，每个中间波形在空间上彼此分离; （b）将每个中间波形的频率分量分散到空间光调制器的不同区域，并用空间光调制器调制至少一些分散的频率分量; 和（c）将每个中间波形的分散频率分量重新组合以产生多个时间成形的输出波形。

公开(公告)号：US20090062632A1

公开(公告)日：2009-03-05

申请号：US11918537

申请日：2006-04-13

Applicant: Mihailo V. Rebec

Inventor： Mihailo V. Rebec

IPC: A61B5/1455

CPC classification number: G01J3/1256 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/1495 ,  A61B5/726 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0262 ,  G01J3/0272 ,  G01J3/10 ,  G01J3/28 ,  G01J3/433 ,  G01J2003/2866 ,  G01N21/35 ,  G01N2021/3144 ,  G01N2021/3185

Abstract: A system for determining an analyte concentration in a fluid sample (e.g., glucose) comprises a light source, a detector, and a central processing unit. The detector is adapted to receive spectral information corresponding to light returned from the fluid sample being analyzed and to convert the received spectral information into an electrical signal indicative of the received spectral information. The central processing unit is adapted to compare the electrical signal to an algorithm built upon correlation with the analyte in body fluid. The algorithm is adapted to convert the received spectral information into the analyte concentration in body fluid. Spectral information is delivered from the central processing unit to the light source and used to vary the intensity and timing of the light to improve the accuracy of conversion into analyte concentration.

Abstract translation: 用于确定流体样品（例如葡萄糖）中的分析物浓度的系统包括光源，检测器和中央处理单元。 检测器适于接收对应于正在分析的流体样品返回的光的光谱信息，并将接收到的光谱信息转换为指示所接收的光谱信息的电信号。 中央处理单元适于将电信号与建立在体液中分析物相关的算法进行比较。 该算法适用于将接收到的光谱信息转换成体液中的分析物浓度。 光谱信息从中央处理单元传送到光源，并用于改变光的强度和时间，以提高转换成分析物浓度的准确度。

公开(公告)号：US07483598B2

公开(公告)日：2009-01-27

申请号：US11079478

申请日：2005-03-15

Applicant: Hans-Peter Loock ,  Zhaoguo Tong

Inventor： Hans-Peter Loock ,  Zhaoguo Tong

IPC: G02B6/00

CPC classification number: G01J3/433 ,  G01J3/0218 ,  G01J9/00 ,  G01N21/7703 ,  G01N2021/7779

Abstract: The invention provides a method and apparatus for measuring one or more optical properties, such as absorbance and refractive index, of a test medium such as a gas, a liquid, or solid material. The method comprises providing a passive optical waveguide loop comprising the test medium, launching in the optical loop an intensity-modulated light at a reference phase, detecting a phase of said light along the optical waveguide loop, and comparing the detected phase of said light along the loop with the reference phase, wherein the comparison provides information about one or more optical properties of the test medium.

Abstract translation: 本发明提供了一种用于测量诸如气体，液体或固体材料的测试介质的一种或多种光学性质（例如吸光度和折射率）的方法和装置。 该方法包括提供包括测试介质的无源光波导环路，在光环路中发射参考相位的强度调制光，检测沿着光波导环路的所述光的相位，并将所检测到的相位沿着 具有参考相位的循环，其中比较提供关于测试介质的一个或多个光学特性的信息。

公开(公告)号：US07480055B2

公开(公告)日：2009-01-20

申请号：US11652778

申请日：2007-01-12

Applicant: Henry L. Buijs ,  Jacques McKinnon

Inventor： Henry L. Buijs ,  Jacques McKinnon

IPC: G01B9/02 ,  G01J3/45

CPC classification number: G01J3/433 ,  G01J3/02 ,  G01J3/0202 ,  G01J3/021 ,  G01J3/4535

Abstract: A two-beam interferometer for Fourier Transform spectroscopy has a double pivot scanning mechanism. The interferometer has two rigid pendulums that are each rotatable to swing around an associated one of distinct axes of rotation. A linkage links the two rigid pendulums to each other and constrains their rotation relative to each other. The interferometer has bearings, which may be flexure bearings, for rotatably mounting the two pendulums to swing around an associated one of the distinct axes of rotation and a first and a second bearing linking the linkage to an associated one of the pendulums. The two rigid pendulums, the linkage and the bearings can be a monolithic structure.

Abstract translation: 用于傅立叶变换光谱的双光束干涉仪具有双重枢转扫描机制。 干涉仪具有两个刚性摆，它们可旋转以围绕不同的旋转轴线相关联地摆动。 连杆将两个刚性摆与彼此连接并约束其相对于彼此的旋转。 干涉仪具有可以是挠性轴承的轴承，用于可旋转地安装两个摆动以围绕相关联的一个不同旋转轴线摆动;以及第一和第二轴承，其将连杆与相关联的一个摆锤连接。 两个刚性摆，连杆和轴承可以是单片结构。