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公开(公告)号：US09927355B2
公开(公告)日：2018-03-27
申请号：US15356722
申请日：2016-11-21
Applicant: University of Massachusetts
Inventor： Robert H. Giles , Gargi Sharma , Cecil S. Joseph
CPC classification number: G01N21/3581 , A61B5/0066 , G01B9/0203 , G01B9/02044 , G01B9/02091 , G01J3/2823 , G01J3/42 , G01J3/45 , G01J3/4535 , G01N21/4795
Abstract: A single-shot terahertz imaging system including an interferometer and a terahertz spectrometer. The interferometer includes a beam splitter configured to receive input terahertz radiation and output first terahertz radiation and second terahertz radiation, a sample configured to reflect the first terahertz radiation, and a mirror configured to reflect the second terahertz radiation. The beam splitter is further configured to receive the reflected first terahertz radiation and the reflected second terahertz radiation, and output interfered terahertz radiation. The terahertz spectrometer is configured to measure the interfered terahertz radiation and includes a frequency dispersive element configured to receive the interfered terahertz radiation and output spatially dispersed terahertz radiation, and a terahertz radiation detector configured to determine the intensity of the spatially dispersed terahertz radiation.
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公开(公告)号：US09921107B2
公开(公告)日：2018-03-20
申请号：US15363186
申请日：2016-11-29
Inventor： Michael Derek Hargreaves , Timothy M. Pastore , Gregory H. Vander Rhodes , Brendon D. Tower
CPC classification number: G01J3/4412 , G01J3/0264 , G01J3/0272 , G01J3/0283 , G01J3/0286 , G01J3/0291 , G01J3/28 , G01J3/44 , G01J3/45 , G01J3/453 , G01J2003/2833 , G01N21/35 , G01N21/65 , G01N2021/3595 , G01N2201/0221
Abstract: A spectrometer system comprising a housing configured as a handheld device with a screen; a source of narrow band illumination; a sensor that detects Raman scattering signals; a source of wide band illumination; an optical element that detect Fourier transform infrared (FTIR) signals; a memory device comprising a library of information with Raman scattering reference information and FTIR reference information; and a processor configured to execute software instructions, wherein the software instructions are configured to: direct the narrow band illumination to the sample; detect the Raman scattering signals; direct the wide band illumination to the sample; detect the FTIR signals; determine a composition of the sample from a similarity between the Raman scattering spectral information and the Raman scattering reference information, and from a similarity between the FTIR spectral information and the FTIR reference information; and display the composition of the sample on the screen.
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公开(公告)号：US20180066990A1
公开(公告)日：2018-03-08
申请号：US15808898
申请日：2017-11-10
Applicant: Technische Universität München
Inventor： Michael Schardt
CPC classification number: G01J3/45 , G01J3/021 , G01J3/453 , G01J3/4531
Abstract: A static Fourier transform spectrometer is disclosed that includes a beam splitter, a mirror device, and a collection optic. The beam splitter divides an input light beam into a first arm and a second arm, wherein the first arm is reflected by the beam splitter and the second arm passes through the beam splitter, wherein the first arm extends to the converging optical unit without deflection after reflection at the mirror device, wherein the second arm extends to the converging optical unit without deflection after passing through the beam splitter, and wherein the collection optic merges the first arm and the second arm for interference.
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公开(公告)号：US20180008147A1
公开(公告)日：2018-01-11
申请号：US15634456
申请日：2017-06-27
Applicant: Duke University
Inventor： Adam Wax , John W. Pyhtila
CPC classification number: A61B5/0084 , A61B1/00165 , A61B1/00172 , A61B5/0066 , A61B5/0075 , G01B9/02043 , G01B9/02044 , G01B9/02084 , G01B9/02087 , G01B9/0209 , G01B9/02091 , G01J3/45 , G01N21/31 , G01N21/4795 , G01N2021/4704 , G01N2021/4709 , G01N2021/4735 , G01N2201/08
Abstract: A method of assessing tissue health comprises the steps of obtaining depth-resolved spectra of a selected area of in vivo tissue, and assessing the health of the selected area based on the depth-resolved structural information of the scatterers. Obtaining depth-resolved spectra of the selected area comprises directing a sample beam towards the selected area at an angle, and receiving an angle-resolved scattered sample beam. The angle-resolved scattered sample beam is cross-correlated with the reference beam to produce an angle-resolved cross-correlated signal about the selected area, which is spectrally dispersed to yield an angle-resolved, spectrally-resolved cross-correlation profile having depth-resolved information about the selected area. The angle-resolved, spectrally-resolved cross-correlation profile is processed to obtain depth-resolved information about scatterers in the selected area.
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公开(公告)号：US20170363473A1
公开(公告)日：2017-12-21
申请号：US15540441
申请日：2016-02-03
Applicant: VITO NV
Inventor： Stefan LIVENS
CPC classification number: G01J3/45 , G01J3/26 , G01J3/28 , G01J3/2803 , G01J3/2823 , G01J2003/2826 , G01J2003/2879
Abstract: A method for estimating an input spectrum from sensor data acquired by an optical sensor assembly, having an aperture, a Fabry-Perot interferometer, and an optical sensor element, the method including: obtaining first calibration data representative of a spectral response function of the optical sensor assembly for a first setting of the aperture; computing second calibration data from the first calibration data, the second calibration data being representative of a spectral response function of the optical sensor assembly for a second setting of the aperture, where the second setting corresponds to a setting applied during the acquiring of the sensor data; and estimating the input spectrum as a function of the second calibration data and the sensor data. Additionally, a corresponding system for estimating an input spectrum
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Patent Agency Ranking
公开(公告)号：US20170314992A1
公开(公告)日：2017-11-02
申请号：US15363186
申请日：2016-11-29
Inventor： Michael Derek HARGREAVES , Timothy M. PASTORE , Gregory H. VANDER RHODES , Brendon D. TOWER
CPC classification number: G01J3/4412 , G01J3/0264 , G01J3/0272 , G01J3/0283 , G01J3/0286 , G01J3/0291 , G01J3/28 , G01J3/44 , G01J3/45 , G01J3/453 , G01J2003/2833 , G01N21/35 , G01N21/65 , G01N2021/3595 , G01N2201/0221
Abstract: A spectrometer system comprising a housing configured as a handheld device with a screen; a source of narrow band illumination; a sensor that detects Raman scattering signals; a source of wide band illumination; an optical element that detect Fourier transform infrared (FTIR) signals; a memory device comprising a library of information with Raman scattering reference information and FTIR reference information; and a processor configured to execute software instructions, wherein the software instructions are configured to: direct the narrow band illumination to the sample; detect the Raman scattering signals; direct the wide band illumination to the sample; detect the FTIR signals; determine a composition of the sample from a similarity between the Raman scattering spectral information and the Raman scattering reference information, and from a similarity between the FTIR spectral information and the FTIR reference information; and display the composition of the sample on the screen.
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367.发明申请公开(公告)号：US20170280992A1
公开(公告)日：2017-10-05
申请号：US15627077
申请日：2017-06-19
Applicant: ABBOTT MEDICAL OPTICS INC.
Inventor： Stanley W. Huth , Denise Tran
CPC classification number: A61B3/101 , A61B3/0025 , A61B3/1005 , G01B11/06 , G01J3/45
Abstract: A method for determining reflectivity of a tear film lipid layer of a patient and recommending a course of treatment based on the same. The method includes the steps of: measuring a tear film aqueous plus lipid layer relative reflectance spectrum using a wavelength-dependent optical interferometer; converting the measured tear film aqueous plus lipid layer relative reflectance spectrum to a calculated absolute reflectance spectrum; comparing the calculated absolute reflectance spectrum to a theoretical absolute lipid reflectance spectrum to determine a tear film lipid layer thickness; and determining a reflectivity value for the tear film lipid layer thickness at a first wavelength of light corresponding to ultraviolet, violet, or blue light.
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公开(公告)号：US09778113B2
公开(公告)日：2017-10-03
申请号：US14253250
申请日：2014-04-15
Inventor： Dirk R. Englund , Chaitanya Rastogi
CPC classification number: G01J3/45 , G01J3/0259 , G01J3/26 , G01J3/2823 , G01J3/32 , G01J2003/2826 , G01J2003/452
Abstract: Techniques for hyperspectral imaging, including a device for hyperspectral imaging including at least one tunable interferometer including a thin layer of material disposed between two or more broadband mirrors. Electrodes placed on either side of the tunable interferometer can be coupled to a voltage control circuit, and upon application of a voltage across the tunable interferometer, the distance between the mirrors can be modulated by physically altering the dimensions of the thin layer of material, which can uniformly load the broadband mirrors. Physically altering the dimensions of the thin layer of material can include one or more of deformation of a soft material, piezostrictrive actuation of a piezostrictrive material, or electrostrictive actuation of an electrostrictive material.
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公开(公告)号：US09687157B2
公开(公告)日：2017-06-27
申请号：US14494080
申请日：2014-09-23
Applicant: Duke University
Inventor： Adam Wax , John W. Pyhtila
CPC classification number: A61B5/0084 , A61B1/00165 , A61B1/00172 , A61B5/0066 , A61B5/0075 , G01B9/02043 , G01B9/02044 , G01B9/02084 , G01B9/02087 , G01B9/0209 , G01B9/02091 , G01J3/45 , G01N21/31 , G01N21/4795 , G01N2021/4704 , G01N2021/4709 , G01N2021/4735 , G01N2201/08
Abstract: A method of assessing tissue health comprises the steps of obtaining depth-resolved spectra of a selected area of in vivo tissue, and assessing the health of the selected area based on the depth-resolved structural information of the scatterers. Obtaining depth-resolved spectra of the selected area comprises directing a sample beam towards the selected area at an angle, and receiving an angle-resolved scattered sample beam. The angle-resolved scattered sample beam is cross-correlated with the reference beam to produce an angle-resolved cross-correlated signal about the selected area, which is spectrally dispersed to yield an angle-resolved, spectrally-resolved cross-correlation profile having depth-resolved information about the selected area. The angle-resolved, spectrally-resolved cross-correlation profile is processed to obtain depth-resolved information about scatterers in the selected area.
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370.发明授权公开(公告)号：US09681802B2
公开(公告)日：2017-06-20
申请号：US14831678
申请日：2015-08-20
Applicant: ABBOTT MEDICAL OPTICS INC.
Inventor： Stanley W. Huth , Denise Tran
CPC classification number: A61B3/101 , A61B3/0025 , A61B3/1005 , G01B11/06 , G01J3/45
Abstract: A method for determining reflectivity of a tear film lipid layer of a patient and recommending a course of treatment based on the same. The method includes the steps of: measuring a tear film aqueous plus lipid layer relative reflectance spectrum using a wavelength-dependent optical interferometer; converting the measured tear film aqueous plus lipid layer relative reflectance spectrum to a calculated absolute reflectance spectrum; comparing the calculated absolute reflectance spectrum to a theoretical absolute lipid reflectance spectrum to determine a tear film lipid layer thickness; and determining a reflectivity value for the tear film lipid layer thickness at a first wavelength of light corresponding to ultraviolet, violet, or blue light.
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