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公开(公告)号：CA2108025C
公开(公告)日：1998-08-04
申请号：CA2108025
申请日：1992-04-07
Applicant: INDIANA UNIVERSITY FOUNDATION
Inventor： HATHAWAY DAVID R , MARCH KEITH L , PATTON BRIAN L , WILENSKY ROBERT L
IPC: A61K31/35 , A61K31/365 , A61K31/37 , A61N5/06 , C07D493/04
Abstract: Restenosis following vascular recanalization is prevented by administering a pho toactivatable psoralen and, in conjunction With recanalization, delivering ultraviolet radiation to the region of said reca nalization.
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公开(公告)号：AU5214198A
公开(公告)日：1998-03-19
申请号：AU5214198
申请日：1998-01-19
Applicant: INDIANA UNIVERSITY FOUNDATION
Inventor： FIELD LOREN J
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公开(公告)号：ZA9701600B
公开(公告)日：1997-09-22
申请号：ZA9701600
申请日：1997-02-25
Applicant: MERCK & CO INC , INDIANA UNIVERSITY FOUNDATION
Inventor： AMON FELIX W , HARRIS ALON
IPC: A61K31/38 , A61K31/381 , A61K31/382 , A61K31/41 , A61K31/433 , A61K31/54 , A61K31/542 , A61P27/02 , C07D20060101 , C07D
CPC classification number: A61K31/382 , A61K31/433 , Y10S514/912
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公开(公告)号：NZ273838A
公开(公告)日：1997-09-22
申请号：NZ27383894
申请日：1994-09-15
Applicant: INDIANA UNIVERSITY FOUNDATION
Inventor： KWON BYOUNG S
IPC: G01N33/53 , A61K38/00 , C07K14/705 , C07K14/715 , C07K14/725 , C07K16/28 , C12N5/10 , C12N5/12 , C12N15/09 , C12N15/12 , C12P21/02 , C12P21/08 , G01N33/566 , G01N33/577 , C07K14/71 , C07K16/22 , C07K19/00 , C12N15/62 , G01N33/68
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公开(公告)号：CA2247063A1
公开(公告)日：1997-08-28
申请号：CA2247063
申请日：1997-02-25
Applicant: INDIANA UNIVERSITY FOUNDATION , ADVANCED RES & TECH INST
Inventor： HARRIS ALON , SPONSEL WILLIAM ERIC
IPC: C07D495/04 , A61K31/00 , A61K31/38 , A61K31/381 , A61K31/382 , A61K31/41 , A61K31/433 , A61K31/54 , A61K31/541 , A61K31/542 , A61K45/00 , A61P27/00 , A61P27/02 , A61P43/00 , C07D513/04 , A61K31/34 , A61K31/40 , A61K31/44 , A61K31/445 , A61K31/495 , A61K31/535
Abstract: There is disclosed a method for treating and/or preventing macular edema and age-related macular degeneration which comprises topical administration of carbonic anhydrase inhibitors to the eye.
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Patent Agency Ranking
公开(公告)号：IL118310D0
公开(公告)日：1996-09-12
申请号：IL11831096
申请日：1996-05-17
Applicant: INDIANA UNIVERSITY FOUNDATION
IPC: A23K1/175 , A23K1/18 , A23L1/304 , A61K20060101 , A61K
Abstract: A chew product useful against the build-up of dental calculus on the teeth of animals contains an amount of sodium hexametaphosphate effective to reduce the development of dental calculus. The chew product in one embodiment is prepared by soaking the product in an aqueous solution containing from about 0.5% to about 3.0% by weight sodium hexametaphosphate. Also disclosed are methods for preparing the novel chew product and for using the chew product containing sodium hexametaphosphate to reduce and/or prevent the build-up of dental calculus on the teeth of animals.
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公开(公告)号：AU4706496A
公开(公告)日：1996-08-14
申请号：AU4706496
申请日：1996-01-26
Applicant: INDIANA UNIVERSITY FOUNDATION
Inventor： FIFE WILMER K , ZELDIN MARTEL , RUBINSZTAJN SLAWOMIR
IPC: A61K6/083 , C07C233/38 , C08F220/60 , C07C69/62 , C07C211/20 , C07C221/00 , C07C225/14 , C08F26/00 , C08F226/00 , C08L39/00
Abstract: Described are novel fluoride ion-releasing acrylic or methacrylic acid-based monomers, fluoride ion-releasing dental resin materials prepared from the monomers, and processes for preparing the monomers and dental resin materials. The monomers of the invention are prepared in good yield from readily available starting materials. Dental resin materials of the invention exhibit excellent sustained fluoride ion release.
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公开(公告)号：NZ253927A
公开(公告)日：1996-06-25
申请号：NZ25392793
申请日：1993-06-15
Applicant: INDIANA UNIVERSITY FOUNDATION
Inventor： STOOKEY GEORGE K
Abstract: The novel agents for preventing dental calculus in domestic animals of the present invention are sequestering agents that are applied as coatings to commercially-prepared diets for domestic animals and that are significantly superior in terms of their anticalculus efficacy to the soluble pyrophosphate crystal growth inhibitors of the prior art. The sequestering agents of the present invention form soluble calcium complexes in saliva and dental plaque fluids thereby preventing the calcification of dental plaque. Sodium hexametaphosphate has been utilized as the preferred sequestering agents of the invention to date.
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公开(公告)号：AU667293B2
公开(公告)日：1996-03-21
申请号：AU8903691
申请日：1991-10-11
Applicant: INDIANA UNIVERSITY FOUNDATION
Inventor： SURZYCKI STEFAN J , KITYAMA MASAHIKO , TOGASAKI ROBERT K
IPC: B02C19/00 , A61M11/06 , B05B7/00 , C12M1/00 , C12M1/33 , C12M3/08 , C12Q1/68 , G01N1/00 , G01N1/28 , G01N1/40 , C07K3/02
Abstract: PCT No. PCT/US91/07530 Sec. 371 Date Mar. 7, 1994 Sec. 102(e) Date Mar. 7, 1994 PCT Filed Oct. 11, 1991 PCT Pub. No. WO92/07091 PCT Pub. Date Apr. 30, 1992Described is an improved process for fragmenting a biomaterial and isolating and recovering a component thereof. The preferred improved process includes the step of performing the fragmentation by nebulizing a liquid medium containing the biomaterial. A preferred process for fragmenting isolated DNA includes the step of nebulizing a fluid containing the DNA. This preferred process provides randomness superior to prior known DNA fragmentation methods, as well as other important advantages. An improved nebulization device is also described.
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公开(公告)号：CA2181787A1
公开(公告)日：1995-09-08
申请号：CA2181787
申请日：1995-03-01
Applicant: GENENTECH INC , INDIANA UNIVERSITY FOUNDATION
Inventor： DOERSCHUK CLAIRE M , FONG SHERMAN , HEBERT CAROLINE ALICE , KIM KYUNG JIN , LEONG STEVEN R
IPC: C12N15/02 , A61K38/00 , A61K39/395 , A61P29/00 , C07H21/04 , C07K16/24 , C12N15/09 , C12P21/08 , C12N15/13 , C07K16/46
Abstract: Anti-IL-8 monoclonal antibodies are described for use in diagnostic applications and in the treatment of inflammatory disorders such as inflammatory bowel disease and bacterial pneumonias.
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