公开(公告)号：GB0218677D0

公开(公告)日：2002-09-18

申请号：GB0218677

申请日：2002-08-12

Applicant: WILSON STUART A

公开(公告)号：GB0213945D0

公开(公告)日：2002-07-31

申请号：GB0213945

申请日：2002-06-18

Applicant: WILSON STUART A

公开(公告)号：ES2153816T3

公开(公告)日：2001-03-16

申请号：ES90903253

申请日：1990-01-30

Applicant: RUBIN JEFFREY S ,  FINCH PAUL W ,  AARONSON STUART A

Inventor： RUBIN JEFFREY S ,  FINCH PAUL W ,  AARONSON STUART A

IPC: A61K39/395 ,  A61K38/00 ,  A61K38/18 ,  A61K38/22 ,  A61P17/02 ,  A61P43/00 ,  C07H21/04 ,  C07K1/16 ,  C07K14/00 ,  C07K14/435 ,  C07K14/47 ,  C07K14/475 ,  C07K14/485 ,  C07K14/50 ,  C07K16/00 ,  C07K16/22 ,  C07K19/00 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/08 ,  C12N5/10 ,  C12N15/09 ,  C12N15/12 ,  C12N15/18 ,  C12N15/63 ,  C12N15/70 ,  C12N15/79 ,  C12P21/00 ,  C12P21/02 ,  C12Q1/68 ,  C12Q1/6876 ,  C12R1/91 ,  G01N33/48 ,  G01N33/50 ,  G01N33/53 ,  C07K1/22 ,  C07K7/06 ,  C07K7/08 ,  C12N5/00 ,  C12N15/00 ,  G01N33/536

Abstract: Discoveries are disclosed that show particular aspect or recombinant DNA technology can be used successfully to produce hitherto unknown human keratinocyte growth factor (KGF) protein free of other polypeptides. These proteins can be produced in various functional forms from spontaneously secreting cells or from DNA segments introduced into cells. These forms variously enable biochemical and functional studies of this novel protein as well as product of antibodies. Means are described fro determining the level of expression of genes for the KGF protein, for example by measuring mRNA levels in cells or by measuring antigen secreted in extracellular or body fluids.

公开(公告)号：CA2373883A1

公开(公告)日：2001-01-11

申请号：CA2373883

申请日：2000-06-30

Applicant: LIPTON STUART A

Inventor： LIPTON STUART A

IPC: C07D401/04 ,  A61K31/00 ,  A61K31/424 ,  A61K31/437 ,  A61K31/4439 ,  A61K31/444 ,  A61K31/4545 ,  A61K31/506 ,  A61K45/00 ,  A61P3/08 ,  A61P3/10 ,  A61P9/10 ,  A61P25/00 ,  A61P25/16 ,  A61P25/18 ,  A61P25/22 ,  A61P25/24 ,  A61P25/28 ,  A61P25/30 ,  A61P27/06 ,  A61P39/02 ,  A61P43/00 ,  C07D401/14 ,  C07D413/04 ,  C07D471/04 ,  C07D513/04 ,  A61K31/40 ,  A61K31/415 ,  A61K31/44

Abstract: The invention relates to a method of reducing neuronal injury or apoptosis including administering to a patient in need thereof an effective amount of a p38 mitogen-activated protein kinase (MAPK) inhibitor. Methods of treating a n HIV-mediated dementia, glaucoma, or other neurodegenerative disorders are al so disclosed.

公开(公告)号：GB0020146D0

公开(公告)日：2000-10-04

申请号：GB0020146

申请日：2000-08-17

Applicant: MOTH STUART A

公开(公告)号：CA2254297A1

公开(公告)日：2000-06-01

申请号：CA2254297

申请日：1998-12-01

Applicant: BEESTON STUART A

Inventor： BEESTON STUART A

IPC: A63B63/00 ,  A63B71/02 ,  A63B63/04

Abstract: A portable, collapsible goal structure with attached net that can be used in the game of hockey is disclosed. The goal structure consists of two U-shaped members, lying in perpendicular planes and forming an "L", each consisting of a series of tubes containing a slot or channel running along the side of each tube and extending into the tube, from one end of the tube to the other to form a continuous slot or channel along the inside of the L shape of the goal structure. Knots at the perimeter of a net are fed into the slots or channels of each tube when the tubes are disconnected from one another. The tubes and the U-shaped members are then connected to one another by elbows and tension release mechanisms. When the tubes are disconnected, the goal structure remains in one piece with each tube connected to the net.

公开(公告)号：SG46699A1

公开(公告)日：1998-02-20

申请号：SG1996008633

申请日：1990-01-30

Applicant: RUBIN JEFFREY S ,  FINCH PAUL W ,  AARONSON STUART A

Inventor： RUBIN JEFFREY S ,  FINCH PAUL W ,  AARONSON STUART A

IPC: A61K39/395 ,  A61K38/00 ,  A61K38/18 ,  A61K38/22 ,  A61P17/02 ,  A61P43/00 ,  C07H21/04 ,  C07K1/16 ,  C07K14/00 ,  C07K14/435 ,  C07K14/47 ,  C07K14/475 ,  C07K14/485 ,  C07K14/50 ,  C07K16/00 ,  C07K16/22 ,  C07K19/00 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/08 ,  C12N5/10 ,  C12N15/09 ,  C12N15/12 ,  C12N15/18 ,  C12N15/63 ,  C12N15/70 ,  C12N15/79 ,  C12P21/00 ,  C12P21/02 ,  C12Q1/68 ,  C12Q1/6876 ,  C12R1/91 ,  G01N33/48 ,  G01N33/50 ,  G01N33/53 ,  C07K1/00 ,  C07K7/06 ,  C07K7/08 ,  C12N5/00 ,  C12N15/00 ,  G01N33/536 ,  C12N ,  G01N

Abstract: Discoveries are disclosed that show particular aspect or recombinant DNA technology can be used successfully to produce hitherto unknown human keratinocyte growth factor (KGF) protein free of other polypeptides. These proteins can be produced in various functional forms from spontaneously secreting cells or from DNA segments introduced into cells. These forms variously enable biochemical and functional studies of this novel protein as well as product of antibodies. Means are described fro determining the level of expression of genes for the KGF protein, for example by measuring mRNA levels in cells or by measuring antigen secreted in extracellular or body fluids.

公开(公告)号：NO972259D0

公开(公告)日：1997-05-16

申请号：NO972259

申请日：1997-05-16

Applicant: RUBIN JEFFREY S ,  FINCH PAUL W ,  AARONSON STUART A

Inventor： RUBIN JEFFREY S ,  FINCH PAUL W ,  AARONSON STUART A

IPC: A61K39/395 ,  A61K38/00 ,  A61K38/18 ,  A61K38/22 ,  A61P17/02 ,  A61P43/00 ,  C07H21/04 ,  C07K1/16 ,  C07K14/00 ,  C07K14/435 ,  C07K14/47 ,  C07K14/475 ,  C07K14/485 ,  C07K14/50 ,  C07K16/00 ,  C07K16/22 ,  C07K19/00 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/08 ,  C12N5/10 ,  C12N15/09 ,  C12N15/12 ,  C12N15/18 ,  C12N15/63 ,  C12N15/70 ,  C12N15/79 ,  C12P21/00 ,  C12P21/02 ,  C12Q1/68 ,  C12Q1/6876 ,  C12R1/91 ,  G01N33/48 ,  G01N33/50 ,  G01N33/53 ,  C12N15/62

Abstract: Discoveries are disclosed that show particular aspect or recombinant DNA technology can be used successfully to produce hitherto unknown human keratinocyte growth factor (KGF) protein free of other polypeptides. These proteins can be produced in various functional forms from spontaneously secreting cells or from DNA segments introduced into cells. These forms variously enable biochemical and functional studies of this novel protein as well as product of antibodies. Means are described fro determining the level of expression of genes for the KGF protein, for example by measuring mRNA levels in cells or by measuring antigen secreted in extracellular or body fluids.

公开(公告)号：GB9622575D0

公开(公告)日：1997-01-08

申请号：GB9622575

申请日：1996-10-30

Applicant: KAY STUART A ,  KAY ALEXANDER T

IPC: G06F15/02

公开(公告)号：CA2108104A1

公开(公告)日：1994-04-09

申请号：CA2108104

申请日：1993-10-08

Applicant: EDWARDSON PETER A D ,  FAIRBROTHER JOHN E ,  GARDNER RONALD S ,  HOLLINGSBEE DEREK A ,  CEDERHOLM WILLIAMS STUART A

Inventor： EDWARDSON PETER A D ,  FAIRBROTHER JOHN E ,  GARDNER RONALD S ,  HOLLINGSBEE DEREK A ,  CEDERHOLM-WILLIAMS STUART A

IPC: A61K35/14 ,  A61K33/06 ,  A61K38/00 ,  A61K38/17 ,  A61K38/36 ,  A61K38/39 ,  A61K38/45 ,  A61K38/48 ,  A61L15/32 ,  A61L17/00 ,  A61L24/00 ,  A61L24/10 ,  A61L27/22 ,  A61L31/00 ,  A61P7/04 ,  C07K1/00 ,  C07K14/00 ,  C07K14/75 ,  C07K16/00 ,  C12N11/06 ,  C12N11/10 ,  G01N33/86 ,  A61L25/00 ,  A61L27/00 ,  A61L15/38

Abstract: The subject invention relates to fibrin sealants. More specifically, the subject invention relates to the use of a fibrin sealant wherein a composition comprising fibrin monomer or a composition comprising noncrosslinked fibrin is utilized as a component of the fibrin sealant.