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1.发明公开METHOD OF REDUCING NEURONAL INJURY OR APOPTOSIS 有权方法ZUR VERRINGERUNG EINES NEURONALEN SCHADENS ODER EINER APOPTOSE
公开(公告)号：EP1196167A4
公开(公告)日：2003-05-02
申请号：EP00948576
申请日：2000-06-30
Applicant: LIPTON STUART A
Inventor： LIPTON STUART A
IPC: C07D401/04 , A61K31/00 , A61K31/424 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/506 , A61K45/00 , A61P3/08 , A61P3/10 , A61P9/10 , A61P25/00 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/30 , A61P27/06 , A61P39/02 , A61P43/00 , C07D401/14 , C07D413/04 , C07D471/04 , C07D513/04 , A61K31/40 , A61K31/415
CPC classification number: A61K31/506 , A61K31/00 , A61K31/4439 , A61K31/444 , A61K31/4545
Abstract: The invention relates to a method of reducing neuronal injury or apoptosis including administering to a patient in need thereof an effective amount of a p38 mitogen-activated protein kinase (MAPK) inhibitor. Methods of treating an HIV-mediated dementia, glaucoma, or other neurodegenerative disorders are also disclosed.
Abstract translation: 本发明涉及一种减少神经元损伤或凋亡的方法，包括向有需要的患者施用有效量的p38丝裂原活化蛋白激酶（MAPK）抑制剂。 还公开了治疗HIV介导的痴呆，青光眼或其它神经变性疾病的方法。
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公开(公告)号：EP1196167A1
公开(公告)日：2002-04-17
申请号：EP00948576.4
申请日：2000-06-30
Applicant: Lipton, Stuart A.
Inventor： Lipton, Stuart A.
IPC: A61K31/40 , A61K31/44 , A61K31/415
CPC classification number: A61K31/506 , A61K31/00 , A61K31/4439 , A61K31/444 , A61K31/4545
Abstract: The invention relates to a method of reducing neuronal injury or apoptosis including administering to a patient in need thereof an effective amount of a p38 mitogen-activated protein kinase (MAPK) inhibitor. Methods of treating an HIV-mediated dementia, glaucoma, or other neurodegenerative disorders are also disclosed.
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3.发明授权
公开(公告)号：EP1196167B1
公开(公告)日：2006-04-19
申请号：EP00948576.4
申请日：2000-06-30
Applicant: Lipton, Stuart A.
Inventor： Lipton, Stuart A.
IPC: A61K31/40 , A61K31/4439 , A61K31/444 , A61K31/506 , A61K31/415 , A61K31/4545 , A61K31/00
CPC classification number: A61K31/506 , A61K31/00 , A61K31/4439 , A61K31/444 , A61K31/4545
Abstract: The invention relates to a method of reducing neuronal injury or apoptosis including administering to a patient in need thereof an effective amount of a p38 mitogen-activated protein kinase (MAPK) inhibitor. Methods of treating an HIV-mediated dementia, glaucoma, or other neurodegenerative disorders are also disclosed.
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公开(公告)号：CA2373883A1
公开(公告)日：2001-01-11
申请号：CA2373883
申请日：2000-06-30
Applicant: LIPTON STUART A
Inventor： LIPTON STUART A
IPC: C07D401/04 , A61K31/00 , A61K31/424 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/506 , A61K45/00 , A61P3/08 , A61P3/10 , A61P9/10 , A61P25/00 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/30 , A61P27/06 , A61P39/02 , A61P43/00 , C07D401/14 , C07D413/04 , C07D471/04 , C07D513/04 , A61K31/40 , A61K31/415 , A61K31/44
Abstract: The invention relates to a method of reducing neuronal injury or apoptosis including administering to a patient in need thereof an effective amount of a p38 mitogen-activated protein kinase (MAPK) inhibitor. Methods of treating a n HIV-mediated dementia, glaucoma, or other neurodegenerative disorders are al so disclosed.
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公开(公告)号：AU6205200A
公开(公告)日：2001-01-22
申请号：AU6205200
申请日：2000-06-30
Applicant: LIPTON STUART A
Inventor： LIPTON STUART A
IPC: C07D401/04 , A61K31/00 , A61K31/424 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/506 , A61K45/00 , A61P3/08 , A61P3/10 , A61P9/10 , A61P25/00 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/30 , A61P27/06 , A61P39/02 , A61P43/00 , C07D401/14 , C07D413/04 , C07D471/04 , C07D513/04 , A61K31/40 , A61K31/44 , A61K31/415
Abstract: The invention relates to a method of reducing neuronal injury or apoptosis including administering to a patient in need thereof an effective amount of a p38 mitogen-activated protein kinase (MAPK) inhibitor. Methods of treating an HIV-mediated dementia, glaucoma, or other neurodegenerative disorders are also disclosed.
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Patent Agency Ranking
公开(公告)号：ES3015758T3
公开(公告)日：2025-05-07
申请号：ES18841846
申请日：2018-07-31
Applicant: LIPTON STUART A
Inventor： LIPTON STUART A
IPC: A61K31/135 , A61K31/165 , A61K45/06 , A61P25/00 , G01N33/50 , G01N33/53 , H04R25/00
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公开(公告)号：AU2018309710A1
公开(公告)日：2020-02-27
申请号：AU2018309710
申请日：2018-07-31
Applicant: LIPTON STUART A
Inventor： LIPTON STUART A
IPC: A61K31/135 , A61K31/165 , A61K45/06 , G01N33/50 , G01N33/53 , H04R25/00
Abstract: Disclosed herein are methods for treating juvenile onset neurological conditions, such as autism (ASD), intellectual disability, or epilepsy, with an inhibitor of N-methyl-D-aspartate receptor (NMDAR). The inhibitor may be NitroSynapsin or a derivative thereof.
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公开(公告)号：DE60027431D1
公开(公告)日：2006-05-24
申请号：DE60027431
申请日：2000-06-30
Applicant: LIPTON STUART A
Inventor： LIPTON STUART A
IPC: A61K31/40 , C07D401/04 , A61K31/00 , A61K31/415 , A61K31/424 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/506 , A61K45/00 , A61P3/08 , A61P3/10 , A61P9/10 , A61P25/00 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/30 , A61P27/06 , A61P39/02 , A61P43/00 , C07D401/14 , C07D413/04 , C07D471/04 , C07D513/04
Abstract: The invention relates to a method of reducing neuronal injury or apoptosis including administering to a patient in need thereof an effective amount of a p38 mitogen-activated protein kinase (MAPK) inhibitor. Methods of treating an HIV-mediated dementia, glaucoma, or other neurodegenerative disorders are also disclosed.
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公开(公告)号：AT323482T
公开(公告)日：2006-05-15
申请号：AT00948576
申请日：2000-06-30
Applicant: LIPTON STUART A
Inventor： LIPTON STUART A
IPC: C07D401/04 , A61K31/00 , A61K31/424 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/506 , A61K45/00 , A61P3/08 , A61P3/10 , A61P9/10 , A61P25/00 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/30 , A61P27/06 , A61P39/02 , A61P43/00 , C07D401/14 , C07D413/04 , C07D471/04 , C07D513/04 , A61K31/40 , A61K31/415
Abstract: The invention relates to a method of reducing neuronal injury or apoptosis including administering to a patient in need thereof an effective amount of a p38 mitogen-activated protein kinase (MAPK) inhibitor. Methods of treating an HIV-mediated dementia, glaucoma, or other neurodegenerative disorders are also disclosed.
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公开(公告)号：AU777275B2
公开(公告)日：2004-10-07
申请号：AU6205200
申请日：2000-06-30
Applicant: LIPTON STUART A
Inventor： LIPTON STUART A
IPC: C07D401/04 , A61K31/00 , A61K31/424 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/506 , A61K45/00 , A61P3/08 , A61P3/10 , A61P9/10 , A61P25/00 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/30 , A61P27/06 , A61P39/02 , A61P43/00 , C07D401/14 , C07D413/04 , C07D471/04 , C07D513/04 , A61K31/40 , A61K31/415 , A61K31/44
Abstract: The invention relates to a method of reducing neuronal injury or apoptosis including administering to a patient in need thereof an effective amount of a p38 mitogen-activated protein kinase (MAPK) inhibitor. Methods of treating an HIV-mediated dementia, glaucoma, or other neurodegenerative disorders are also disclosed.
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