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公开(公告)号：KR1020090056313A
公开(公告)日：2009-06-03
申请号：KR1020070123410
申请日：2007-11-30
Applicant: (주)아모레퍼시픽
Abstract: A fermented green tea and a preparation method thereof are provided to reduce astringent and bitter taste of fermented green tea and to remove smells of various bacteria by aging and fermenting green tea using a food microorganism under the optimal condition. A method for preparing fermented green tea comprises the following steps of: adding water to green tea leaves until the moisture content becomes 30-60% on a total weight basis and inoculating bacteria to the green tea leaves; fermenting the inoculated green tea leaves under the condition of 7~35°C and 4.0~8.0 of pH for 1-10 days; and aging the fermented green tea leaves for 7-15 days. The aging step is performed at 5~20°C with basalt laying on the fermented green tea leaves. The bacteria are selected among Saccharomyces cerevisiae, Lactobacillus casei, Bacillus subtilis, Lactobacillus bulgaricus, Lactobacillus plantarum and Leuconostoc mesenteroides.
Abstract translation: 提供发酵绿茶及其制备方法，以减少发酵绿茶的涩味和苦味，并且在最佳条件下使用食品微生物老化和发酵绿茶来除去各种细菌的气味。 制备发酵绿茶的方法包括以下步骤：向绿茶叶中加入水，直到水分含量以总重量计为30-60％，并将细菌接种到绿茶叶上; 在7〜35℃，4.0〜8.0的pH值条件下将接种的绿茶叶发酵1-10天; 并将发酵的绿茶叶老化7-15天。 老化步骤在5〜20℃下进行，玄武岩放在发酵绿茶叶上。 细菌选自酿酒酵母，干酪乳杆菌，枯草芽孢杆菌，保加利亚乳杆菌，植物乳杆菌和肠系膜细菌肠炎肠杆菌。
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32.发明授权
公开(公告)号：KR100897908B1
公开(公告)日：2009-05-18
申请号：KR1020020028646
申请日：2002-05-23
Applicant: (주)아모레퍼시픽
Abstract: 본 발명은 프럭토스 1,6-디포스페이트(D-fructose 1,6-diphosphate) 또는 그 유도체를 유효성분으로 함유하여 피부의 건조증상을 개선함을 특징으로 하는 피부외용제 조성물에 관한 것으로, 보다 상세하게는 피부세포의 분화를 촉진하여 새로운 각질의 재생산을 돕고, 피부에 보습기능을 담당하고 있는 천연보습인자(natural moisturizing factor, NMF)를 생산하고, 피부 내부로부터 수분유지에 필요한 지질의 합성을 증가시킴으로써, 피부의 수분함유능력 증강, 피부 건조의 방지, 그리고 아토피(atopy) 및 접촉성 피부염 증상의 예방, 개선 또는 치료에 효과가 있는 프럭토스 1,6-디포스페이트 또는 그 유도체를 함유하는 피부 외용제 조성물에 관한 것이다.
프럭토스 1,6-디포스페이트(D-fructose 1,6-diphosphate) * 보습 * 각질형성세포 분화 * 필라그린 * 지질생합성 * 세라마이드 * 천연보습인자 * 피부건조 * 아토피 * 접촉성 피부염-
公开(公告)号：KR1020080006895A
公开(公告)日：2008-01-17
申请号：KR1020060066207
申请日：2006-07-14
Applicant: (주)아모레퍼시픽
Abstract: A method of manufacturing green tea with a high content of Gallocatechin-3-gallate(GCG) by subjecting green tea leaf to steam treatment at high temperature and pressure to epimerize epigallocatechin-3-gallate(EGCG) after steaming or roasting treatment of the green tea leaf is provided to increase the content of GCG by a thermal conversion method. To make green tea with a high content of Gallocatechin-3-gallate, green tea leaf is treated with steam or roasted. In the process, the steam treatment is performed more than 2 times or roasting time is increased by more than 20%. The steam treatment or roasting is performed within 30min. After the steam treatment or roasting, steam sterilization treatment is additionally performed for 1 to 240min.
Abstract translation: 一种通过在高温高压下对绿茶叶进行蒸汽处理来制造具有高含量的Gallocatechin-3-没食子酸酯（GCG）的绿茶的方法，以在对绿色的蒸汽或焙烧处理后对表没食子儿茶素-3-没食子酸酯（EGCG）进行差向异构化 提供茶叶以通过热转化方法增加GCG的含量。 为了制备高含量的Gallocatechin-3-没食子酸酯的绿茶，用蒸汽或焙烤处理绿茶叶。 在此过程中，蒸汽处理时间超过2次，焙烧时间提高20％以上。 蒸汽处理或焙烧在30分钟内进行。 蒸汽处理或焙烧后，进行1〜240分钟的蒸汽灭菌处理。
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公开(公告)号：KR1020080004906A
公开(公告)日：2008-01-10
申请号：KR1020060063824
申请日：2006-07-07
Applicant: (주)아모레퍼시픽
IPC: C07D311/04 , A61K31/353
CPC classification number: C07D311/58
Abstract: A method for preparing gallocatechin gallate is provided to increase the solubility of epigallocatechin gallate into a reaction solvent by using an organic solvent and increase the conversion rate into the gallocatechin gallate through epimerization by adjusting the pH, thereby capable of increasing the production amount of the gallocatechin gallate. A method for preparing gallocatechin gallate comprises a step of converting epigallocatechin gallate into the gallocatechin gallate by dissolving the epigallocatechin gallate in an alcohol-based solvent such as ethanol and methanol or a polyol based solvent such as butylene glycol, propylene glycol and polyethylene glycol and then heating the solution at a temperature of about 120 deg.C for 30-60 minutes.
Abstract translation: 提供了没食子儿茶素没食子酸酯的制备方法，以通过使用有机溶剂提高表没食子儿茶素没食子酸酯在反应溶剂中的溶解度，并通过调节pH提高通过差向异构化得到的儿茶素没食子酸酯的转化率，从而能够增加喜树碱的产生量 没食子酸酯。 没食子酸儿茶素没食子酸酯的制备方法包括将表没食子儿茶素没食子酸酯溶解在醇类溶剂如乙醇和甲醇或多元醇类溶剂如丁二醇，丙二醇和聚乙二醇中，将表没食子儿茶素没食子酸酯转化为喜树碱没食子酸酯，然后 在约120℃的温度下加热溶液30-60分钟。
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公开(公告)号：KR1020070106822A
公开(公告)日：2007-11-06
申请号：KR1020060039138
申请日：2006-05-01
Applicant: (주)아모레퍼시픽
IPC: A61K31/353 , A61P3/10
CPC classification number: A61K31/353
Abstract: A composition containing (-)catechin is provided to increase expression of adiponectin by inhibiting expression of a transition factor KLF7(Kruppel-like factor 7) and promotes sugar absorption in adipocytes of mammals, so that the composition is useful for preventing and treating diabetes mellitus, arteriosclerosis and obesity. A composition for preventing and treating diabetes mellitus, arteriosclerosis and obesity contains 0.01-30 wt.%, preferably 1-15 wt.% of (-)catechin represented by the formula(1), wherein the (-)catechin is isolated from green tea. The daily dosage of (-)catechin is 0.1-50 mg/kg, preferably 1-20 mg/kg and the expression of adiponectin in a mammal adipocyte is increased by treating an adipocyte with (-)catechin for 24 hours.
Abstract translation: 提供含有（ - ）儿茶素的组合物，通过抑制转录因子KLF7（Kruppel样因子7）的表达来增加脂联素的表达，并促进哺乳动物脂肪细胞中的糖吸收，使得该组合物可用于预防和治疗糖尿病 ，动脉硬化和肥胖。 用于预防和治疗糖尿病，动脉硬化和肥胖症的组合物含有0.01-30重量％，优选1-15重量％的由式（1）表示的（ - ）儿茶素，其中（ - ）儿茶素与绿色分离 茶。 （ - ）儿茶素的日剂量为0.1-50mg / kg，优选为1-20mg / kg，通过用（ - ）儿茶素处理脂肪细胞24小时，哺乳动物脂肪细胞中脂联素的表达增加。
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Patent Agency Ranking
公开(公告)号：KR1020070094340A
公开(公告)日：2007-09-20
申请号：KR1020060024905
申请日：2006-03-17
Applicant: (주)아모레퍼시픽
Abstract: 본발명은녹차성분및 백자인추출물을함유하여피지분비억제효과를나타내는화장료조성물에관한것으로, 더욱상세하게는녹차추출물또는녹차구성성분인카테킨(catechins)류, 플라보놀 (flavonols)류및 그유도체로이루어진군에서선택된 1종이상과백자인추출물을일정한성분비로함유함으로써과잉피지억제효과및 여드름완화효과를갖는화장료조성물에관한것이다.
Abstract translation: 提供化妆品组合物，以一定比例包含绿茶或绿茶提取物中含有的成分和东方蓟马提取物，以一定比例控制皮脂的代谢，从而有效减轻或改善痤疮并抑制过多的皮脂。 化妆品组合物包含0.001-30.0重量％的绿茶成分，例如绿茶，儿茶素，黄酮醇或其衍生物作为有效成分的提取物，以及Thujae orientalis Semen的提取物，其中儿茶素是表没食子儿茶素（EGCG） ，并且没食子儿茶素没食子酸gallocatechin（GCG）和黄酮醇是槲皮素，山奈酚和杨梅素。
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公开(公告)号：KR1020070014672A
公开(公告)日：2007-02-01
申请号：KR1020050069506
申请日：2005-07-29
Applicant: (주)아모레퍼시픽
Abstract: A skin external composition for inhibiting phagocytosis of keratinocytes comprising genistein or daidzein is provided to reduce mobility of melanosomes transferred from melanocytes in keratinocytes by inhibiting phagocytosis of keratinocytes activated by exposure to ultra violet ray without cytotoxicity, so that chloasma, freckles and speckles are treated and prevented. The skin external composition for inhibiting phagocytosis of keratinocytes comprises at least one selected from genistein and daidzein, wherein the amount of genistein or daidzein is 0.0001-10 wt.%; the genistein or daidzein is an isoflavone produced from Leguminosae plants and shows estrogen effects; and the composition is formulated as cream, lotion, ointment, aqueous solution, suspension, dispersion or emulsion.
Abstract translation: 提供了一种用于抑制包含染料木黄酮或黄豆苷原的角质形成细胞吞噬作用的皮肤外用组合物，以通过抑制通过暴露于紫外线而没有细胞毒性活化的角质形成细胞的吞噬作用来降低角质形成细胞中从黑素细胞转移的黑素体的移动性，从而处理黄褐斑，雀斑和斑点 预防。 用于抑制角化细胞吞噬的皮肤外用组合物包含选自染料木黄酮和黄豆苷原中的至少一种，其中染料木黄酮或黄豆苷原的量为0.0001-10重量％; 染料木素或黄豆苷原是由豆科植物产生的异黄酮，显示雌激素作用; 并将组合物配制成霜剂，洗剂，软膏，水溶液，悬浮液，分散体或乳液。
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公开(公告)号：KR1020070002409A
公开(公告)日：2007-01-05
申请号：KR1020050057934
申请日：2005-06-30
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/97 , A61K8/0212 , A61Q19/08
Abstract: A cosmetic composition comprising the extract of Equisetum arvense L. as an effective ingredient is provided to promote growth of keratinocytes, remove reactive oxygen species, increase biosynthesis of procollagen type 1 by reducing biosynthesis of MMP-1(matrix metaloproteinase-1), and inhibit aging. The cosmetic composition for promoting growth of keratinocytes, removing reactive oxygen species, increasing biosynthesis of procollagen type 1 by reducing biosynthesis of MMP-1, or inhibiting aging comprises the extract of Equisetum arvense L. and at least one extract selected from Lonicera japonica Thunberg extract, Prunus armeniaca extract, Plantago asiatica extract and Coix lacryma-jobi extract, wherein the amount of the medicinal herb extract is 0.0001 to 25 wt.% based on the total weight of the composition; the medicinal herb extracts are prepared with water; and the composition further comprises 1,3-butyleneglycol.
Abstract translation: 提供了含有作为有效成分的马齿苋提取物的化妆品组合物，用于促进角质形成细胞的生长，去除活性氧，通过降低MMP-1（基质金属蛋白酶-1）的生物合成来增加1型前胶原的生物合成，抑制 老化。 用于促进角质形成细胞生长，去除活性氧的化妆品组合物，通过减少MMP-1的生物合成增加生物合成1型前胶原或抑制老化的化妆品组合物包括马齿苋提取物和至少一种选自金银花提取物（Lonicera japonica Thunberg extract）的提取物 ，山茱萸提取物，车前草提取物和枸杞提取物，其中药草提取物的量为组合物总重量的0.0001〜25重量％ 药草提取物用水制备; 并且组合物还包含1,3-丁二醇。
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公开(公告)号：KR1020030077271A
公开(公告)日：2003-10-01
申请号：KR1020020016298
申请日：2002-03-26
Applicant: (주)아모레퍼시픽
IPC: C07K5/10
CPC classification number: C07K5/1016 , A61K8/64 , A61K38/07 , A61Q19/00 , A61Q19/02
Abstract: PURPOSE: Provided is a melanogenesis-suppressing peptide which effectively suppresses the activation of tyrosinase in the melanogenesis cells. A topical skin-whitening composition containing the melanogenesis-suppressing peptide involves excellent skin whitening effect, and effective improvement and prevention of chloasma, freckles, and other melanin pigmentation. CONSTITUTION: The melanogenesis-suppressing peptide is selected from the group consisting of peptides with the amino acid sequences of SEQ ID NO 1-4. A method of manufacturing the melanogenesis-suppressing peptide comprises the steps of preparing chemical peptide random-sequenced mixtures with 76 cases of 4(locations)x19(amino acids); selecting two or three amino acids per the respective peptide locations with enzyme activity inhibitory effect from the peptide mixtures using tyrosinase extracted from mushrooms; synthesizing secondary peptides based on the selected peptide sequences; and testing the whitening effect and the cell stability of the secondary peptides, and finally selecting the peptide with the amino acid sequences of SEQ ID NO 1-4.
Abstract translation: 目的：提供有效抑制黑素生成细胞中酪氨酸酶活化的黑素生成抑制肽。 含有黑素生成抑制肽的局部皮肤美白组合物具有优异的皮肤美白效果，有效改善和防止黄褐斑，雀斑和其他黑色素色素沉着。 构成：黑素生成抑制肽选自具有SEQ ID NO 1-4的氨基酸序列的肽。 制备黑素生成抑制肽的方法包括以下步骤：制备具有76个4（位置）x19（氨基酸）的76个化学肽随机排序的混合物; 使用从蘑菇提取的酪氨酸酶从肽混合物中选择两个或三个氨基酸，每个肽位置具有酶活性抑制作用; 基于所选择的肽序列合成二级肽; 并测试第二肽的美白效果和细胞稳定性，最后选择具有SEQ ID NO 1-4的氨基酸序列的肽。
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公开(公告)号：KR101189989B1
公开(公告)日：2012-10-12
申请号：KR1020050057934
申请日：2005-06-30
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/97 , A61K8/0212 , A61Q19/08
Abstract: 본 발명은 유효성분으로 문형 추출물에 인동 추출물, 행인 추출물, 감국 추출물 및 의이인 추출물로 이루어진 군으로부터 선택된 하나 이상을 더 함유하는 조성물에 관한 것으로, 더 구체적으로는 각질형성세포 성장촉진 효과, 활성산소 소거효과, MMP-1의 생합성 감소를 통한 타입 1 프로콜라겐의 생합성촉진 효과 및 노화방지 효과를 가지는 조성물에 관한 것이다.
문형*인동*행인*감국*의이인*각질형성세포*활성산소*타입1 프로콜라겐
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