Abstract:
PURPOSE: A composition for preventing or curing the metabolic syndrome related-diseases is provided to prevent or cure metabolic syndrome-related diseases including the obesity the hyperlipidemia, the hypertension, the arteriosclerosis, or the hyperinsulinemia etc. by using a 4-hydroxytamoxifen analog (GSK5182) which suppresses a fat synthesis, lowering glucose levels in blood, reducing the total cholesterol in blood, and reducing body fat. CONSTITUTION: A pharmaceutical composition for preventing or curing metabolic syndrome related-diseases comprises the chemical formula 1 of 4-hydroxy tamoxifen analog or its pharmaceutically acceptable salt as an active ingredient. The composition additionally comprises a pharmaceutically acceptable carrier. The metabolic syndrome related-diseases are more than one selected from a group comprising the obesity, the hyperlipidemia, the hypertension, the arteriosclerosis, and the hyperinsulinemia. The composition suppresses accumulation of fat, and reduces size of fat cell and body fat. [Reference numerals] (AA) Weight; (BB) Fat weight; (CC) Before injection; (DD) After injection; (EE,GG,KK,JJ) Control group; (FF,HH,LL) GSK5182 injected group; (II) Fat ratio
Abstract:
PURPOSE: An electric component and a manufacturing method thereof are provided to improve performance of a transistor by separating a functional element part from a substrate and transferring it to other substrate. CONSTITUTION: A carbon layer(20) comprises graphene. A thin film layer(30) is formed on the carbon layer. A channel layer is formed on the thin film layer. A current blocking layer(40) cuts off current flow between the channel layer and the thin film layer. A source electrode and a drain electrode are formed on the channel layer.
Abstract:
PURPOSE: A composition containing a 4-hydroxy tamoxifen analog for preventing or treating liver diseases is provided to reduce GOT(glutamyl oxaloacetic transaminase) and GPT(glutamyl pyruvate transaminase) level and to prevent and treat liver diseases. CONSTITUTION: A pharmaceutical composition for preventing or treating liver diseases contains a 4-hydroxy tamoxifen analog of chemical formula 1 or a pharmaceutically acceptable salt thereof as an active ingredient. The pharmaceutical composition additionally contains a pharmaceutically acceptable carrier. The liver diseases are non-alcoholic or alcoholic fatty liver. The pharmaceutical composition reduces fat accumulation in the liver. The non-alcoholic fatty liver is non-alcoholic steatohepatitis or late phase fibrosis liver diseases. A food composition for preventing or treating liver diseases contains 4-hydroxy tamoxifen analog of chemical formula 1 or sitologically acceptable salt thereof as an active ingredient.
Abstract:
PURPOSE: A composition containing GSK5182 for preventing or treating diabetes is provided to suppress glucose generation gene expression and to lower glucose levels in blood. CONSTITUTION: A pharmaceutical composition for preventing or treating diabetes contains a 4-hydroxy tamoxifen derivative of chemical formula 1 or a pharmaceutically acceptable salt thereof as an active ingredient. The pharmaceutical composition additionally contains a pharmaceutically acceptable carrier. The pharmaceutical composition reduces glucose levels in blood. A food composition for preventing or treating diabetes contains the derivative thereof or a sitologically acceptable salt thereof as an active ingredient.
Abstract:
발광 디바이스와 이의 제조 방법을 제공한다. 발광 디바이스는, ⅰ) 기판, ⅱ) 기판 위에 위치하며, 하나 이상의 개구부를 가지는 마스크층, ⅲ) 개구부를 둘러싸며 마스크층 위에 형성되고, 기판의 판면에 실질적으로 수직인 방향으로 뻗은 발광 구조체, ⅳ) 발광 구조체의 외면과 면접촉을 하며 마스크층 위에 형성된 제1 전극, 및 ⅴ) 발광 구조체의 내부에 위치하여 발광 구조체의 내면과 면접촉을 하는 제2 전극을 포함한다. 기판, 마스크층, 발광, 나노, 튜브, 전극, 씨드층, 절연층
Abstract:
본 발명의 일 실시예에 따른 반도체 발광소자는, 두께와 인듐(In)의 함량이 다른 결정면들을 갖는 활성층 및 박막 형태의 도전형 반도체층으로 인해 인가되는 전압에 따라 상기 결정면들에서 발생되는 발광 파장이 연속적으로 변하며, 형광체 없이 백색광을 제공할 수 있다. 또한, 본 발명의 일 측에 따른 반도체 발광소자는, 마이크로 또는 나노 구조물인 코어부 상에 활성층을 형성함으로써 발광 면적을 확대할 수 있다.