公开(公告)号：KR1020110093279A

公开(公告)日：2011-08-18

申请号：KR1020100013217

申请日：2010-02-12

Applicant: 조선대학교산학협력단

Inventor： 오원근 ,  누엔피헝 ,  누엔티녹안 ,  강후원

IPC: A61K31/343 ,  A61K31/34 ,  A61K36/25 ,  A61P3/04

Abstract: PURPOSE: A compound which activates Erythrina abyssinica-derived AMPK is provided to prevent and treat diabetes, obesity, or metabolic syndrome with less cytotoxicity. CONSTITUTION: An Erythrina abyssinica extract for preventing or treating obesity or metabolic syndrome contains erythribyssin F, erythribyssin N, erythribyssin O, sigmoidin K, isosojagol, eryvarin, or erypoegin F. A health food or pharmaceutical composition for preventing or treating obesity or metabolic syndrome contains the Erythrina abyssinica extract as an active ingredient. The pharmaceutical composition also contains pharmaceutically acceptable carrier or excipient.

Abstract translation: 目的：提供一种激活源自艾氏黑质素的AMPK的化合物，以预防和治疗糖尿病，肥胖或代谢综合征，细胞毒性较小。 构成：用于预防或治疗肥胖症或代谢综合征的黑曜石提取物含有赤藓红F，红细菌素N，赤藓糖苷O，乙状结肠素K，异山梨醇，赤藓红或紫杉醇F.用于预防或治疗肥胖或代谢综合症的保健食品或药物组合物含有 白芷提取物作为活性成分。 药物组合物还含有药学上可接受的载体或赋形剂。

公开(公告)号：KR100962334B1

公开(公告)日：2010-06-10

申请号：KR1020090099238

申请日：2009-10-19

Applicant: 주식회사 중앙백신연구소 ,  조선대학교산학협력단

Inventor： 김은희 ,  유성식 ,  원호근 ,  오원근 ,  박준수 ,  강후원 ,  누엔티녹안

IPC: A61K36/9066 ,  A61P31/16 ,  A23L1/30 ,  A61K31/12

CPC classification number: A61K31/12 ,  A23L33/105 ,  A23V2002/00 ,  A61K36/9066 ,  A23V2250/21

Abstract: PURPOSE: A composition containing diaryheptanoid compounds for preventing and treating avian and swine influenza and novel swine-origin influenza A is provided to non-selectively suppress neuraminidase. CONSTITUTION: A pharmaceutical composition for preventing or treating oseltamivir phosphate-resistant novel swine-origin influenza A contains Curcuma longa extract as an active ingredient. The Curcuma longa extract contains bisdemethoxycurcumin, demethoxycurcumin, or curcumine. The Curcuma longa extract is obtained using ethanol, methanol, acetone, ethyl acetate, or chloroform. A health food for preventing or treating Tamiflu resistant novel swine-origin influenza A contains bisdemethoxycurcumin, demethoxycurcumin, or curcumine.

Abstract translation: 目的：提供一种含有用于预防和治疗禽流感和猪流感病毒的日化类固醇化合物和新型猪源甲型流感病毒的组合物，用于非选择性抑制神经氨酸酶。 构成：用于预防或治疗磷酸奥司他韦的新型猪源甲型流感A的药物组合物含有姜黄提取物作为活性成分。 姜黄提取物含有二去甲氧基姜黄素，去甲氧基姜黄素或姜黄素。 使用乙醇，甲醇，丙酮，乙酸乙酯或氯仿得到姜黄提取物。 用于预防或治疗Tamiflu抗性的猪源甲型流感A的保健食品含有双二甲氧基姜黄素，去甲氧基姜黄素或姜黄素。

公开(公告)号：KR1020100054638A

公开(公告)日：2010-05-25

申请号：KR1020080113632

申请日：2008-11-14

Applicant: 조선대학교산학협력단

Inventor： 오원근 ,  배기환 ,  텅풍티엔 ,  누엔두이투완

IPC: A23L1/30 ,  A23L33/00

CPC classification number: A23L33/105 ,  A23V2002/00 ,  A23V2200/02 ,  A23V2200/326 ,  A23V2250/2132 ,  A23V2250/214 ,  A61K31/216

Abstract: PURPOSE: Phenolic compounds having antioxidant activity from Ilex kudingcha extract and functional food containing the same are provided to prevent or treat diseases caused by active oxygen containing oxygen-resistant compounds as beneficial components. CONSTITUTION: The health food contains Ilex kudingcha methanol extract as active ingredients. The Ilex kudingcha methanol extract includes a compound 1[3-caffeoylquinic acid], a compound 2 [5-caffeoylquinicacid], a compound 3 [4-caffeoylquinic acid], a compound 4 [4-caffeoylquinic acid methyl ester, a compound 5[4,5-dicaffeoylquinic acid methyl ester], a compo0und 6 [3,5-dicaffeoylquinic acid methyl ester], a compound 7[caffeoic acid methyl ester], a compound 8 [3,4-dicaffeoylquinic acid methyl ester] and a compound 9 [3,5-di-O-caffeoyl-epi-quinic acid n-butyl ester].

Abstract translation: 目的：提供具有来自枸杞提取物和含有其的功能性食品的抗氧化活性的酚类化合物，以预防或治疗由含活性氧的耐氧化合物引起的疾病作为有益成分。 规定：保健食品含有枸杞子甲醇提取物作为活性成分。 枸杞醇甲醇提取物包括化合物1 [3-咖啡酰奎宁酸]，化合物2 [5-咖啡酰奎宁酸]，化合物3 [4-咖啡酰奎宁酸]，化合物4 [4-咖啡酰奎宁酸甲酯，化合物5 [ 4,5-二脱酰基奎尼酸甲酯]，化合物7 [椰子酸甲酯]，化合物8 [3,4-二脱酰奎尼酸甲酯]和化合物 9 [3,5-二-O-咖啡酰基 - 邻 - 奎尼酸正丁酯]。

公开(公告)号：KR100950445B1

公开(公告)日：2010-04-02

申请号：KR1020090101628

申请日：2009-10-26

Applicant: 주식회사 중앙백신연구소 ,  조선대학교산학협력단

Inventor： 윤인중 ,  이홍식 ,  김동원 ,  오원근 ,  박준수 ,  부이탄텅 ,  다오트롱투완

IPC: A61K36/484 ,  A61P31/16 ,  A23L1/30 ,  A61K31/12

CPC classification number: A61K31/12 ,  A23K20/111 ,  A23L2/52 ,  A23L29/035 ,  A61K36/484 ,  A61K2236/333 ,  Y10S514/888

Abstract: PURPOSE: A Glycyrrhiza uralensis extract and calcone based compounds suppressing neuraminidase are provided to treat novel swine-origin influenza. CONSTITUTION: A Glycyrrhiza uralensis extract for preventing or treating avian and swine ingluenza contains is extracted using ethanol or methanol and contains chalcone based compound. The chalcone based compound is Licochacone F, Echicnatin, Licochalcon D, Licochalcone A, Isoliquiritigenin, Licoagrochalcone A, 5-Prenylbutein and Kanzonol C. A functional health food for preventing or treating diseases relating to avian and swine influenza contains Glycyrrhiza uralensis extract. A pharmaceutical composition for preventing or treating diseases relating to avian and swine influenza contains Glycyrrhiza uralensis extract or chalcone compouns as active ingredient. The pharmaceutical composition also contains pharmaceutically acceptable carrier or excipient.

Abstract translation: 目的：提供甘草提取物和基于煅烧物的抑制神经氨酸酶的化合物，用于治疗新型猪源性流感。 构成：用乙醇或甲醇提取用于预防或治疗禽流感和猪流感病毒的甘草提取物，并含有查耳酮基化合物。 基于查耳酮的化合物是Licochacone F，Echicnatin，Licochalcon D，Licochalcone A，Isoliquiritigenin，Licoagrochalcone A，5-丙氨酸丁醇和Kanzonol C.用于预防或治疗与禽流感和猪流感有关的疾病的功能保健食品含有甘草提取物。 用于预防或治疗与禽流感和猪流感有关的疾病的药物组合物含有甘草提取物或查耳酮组合物作为活性成分。 药物组合物还含有药学上可接受的载体或赋形剂。