Abstract:
PURPOSE: A brushite substitute for a bone graft is provided to be developed as an ideal substitute for a bone graft by improving water-absorption properties. CONSTITUTION: A brushite substitute for a bone graft includes mussel adhesion protein. The mussel adhesion protein is fp-151 protein. The brushite is based on a beta-tricalcium phosphate/monocalcium phosphate monohydrate. A method for manufacturing the brushite substitute for a bone graft comprises the following steps. The mussel adhesion protein fp-151 is manufactured. A hardening solution is made using the mussel adhesion protein fp-151. The hardening solution and beta-tricalcium phosphate/monocalcium phosphate monohydrate are mixed. The mixture is molded.
Abstract:
A multi-biomolecule detection plate of pattern recognition type is provided to analyze the patteren of signal generated from biomolecule probe and easily detect pathogenic microorganism. A multi-biomolecule detection plate of pattern recognition comprises a specific biomolecule probe of 2-100 rows and identical standard biomolecule probe row on a substrate. The specific biomolecule probe rows are different each other and parallel. The standard biomolecule probe row is parallel with the specific biomolecule probe row and the probes are arranged in turn. A detection plate analyzes the pattern of signal generated from the biomolecule probe. The biomolecule probe is selected from oligonucleotide, cDNA, protein, carbonhydrate and metabolic product. The biomolecule is originated from pathogenic microorganism. The microorganism is Baillus, Camphylobacter, Clostridium, Escherichia, Legionella, Listeria, Salmonella, Shigella, Staphylococcus, Vibrio, and Yersinia.
Abstract:
A method for immobilizing saccharide on the surface of a substrate is provided to immobilize directly the saccharide on the surface of a solid substrate without changing the structure of the saccharide and is applied to various saccharides. A method for immobilizing saccharide on the surface of a substrate such as gold comprises the steps of: (a) reacting an aldehyde of the saccharide selected from the group consisting of reducing monosaccharide, oligosaccharide having a terminal reducing sugar, and polysaccharide with an amine group of an amine compound represented by NH2-R-SH(where R is CC30-50 alkylene, C6-30 aryl or C6-30 aryl including C10-30 alkylene) to prepare a thiol group bound saccharide; and coating the thiol group bound saccharide to the surface of the substrate to bind the thio to the substrate surface, where when the saccharide is a monosaccharide, the reaction is done at a temperature of 20-90 deg.C for 0.5-2 hours, and when the saccharide is a polysaccharide, the reaction is done at a temperature of 30-90 deg.C for 0.5-2 hours. The method further comprises a step of reducing the thiol bound saccharide.
Abstract:
Provided is a photosensitive sterilizer for microorganism comprising polyoxometalate showing strong microorganism sterilizing capacity due to excellent oxidizing property so as to be used for sterilizing the microorganism. The photosensitive sterilizer for microorganism comprises polyoxometalate which is at least one selected from the group consisting of H3PW12O40, H4SiW12O40 and H3Mo12O40P. The method for sterilizing microorganism comprises the steps of: (a) adding the photosensitive sterilizer for microorganism to the microorganism to prepare a mixture; and (b) applying light to the mixture.
Abstract:
본발명은홍합접착단백질기반의자기장감응성마이크로입자및 이의제조방법에관한것이다. 본발명에따른홍합접착단백질기반의마이크로입자는최소침습형세포/약물전달체로서, 자기장을이용하여원격조절방식으로치료용세포/약물을표적화및 국소전달하는데효율적으로적용할수 있다. 또한, 생체적합성과부착능을기반으로조직공학용지지체등에폭넓게응용될수 있다.