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    석곡을 포함하는 신장 질환의 예방 또는 치료용 조성물
    31.
    发明公开
    석곡을 포함하는 신장 질환의 예방 또는 치료용 조성물 有权
    用于预防或治疗肾病的组合物

    公开(公告)号：KR1020130109495A

    公开(公告)日：2013-10-08

    申请号：KR1020120031250

    申请日：2012-03-27

    Applicant: 한국과학기술연구원

    Inventor： 김수남 ,  강기성 ,  이우정 ,  정유정 ,  전영식 ,  이지환 ,  황예란 ,  함정엽

    IPC: A61K36/8984 ,  A61P13/12

    CPC classification number: A61K36/8984 ,  A23L33/105 ,  A23V2002/00 ,  A23V2200/30

    Abstract: PURPOSE: A composition containing Dendrobium moniliforme for preventing or treating renal diseases is provided to lessen side effects when the composition is applied to human body and to show less resistance even after long-term use. CONSTITUTION: A composition for preventing or treating renal diseases contains 0.001-10 wt% of a Dendrobium moniliforme extract as an active ingredient. The extract is a C1-C6 alcohol extract of Dendrobium moniliforme. C1-C6 alcohol is methanol or ethanol. The composition is used for reducing serum creatinine. [Reference numerals] (AA) Sell survival rate (%); (BB) Dendrobium monile

    Abstract translation: 目的：提供一种用于预防或治疗肾脏疾病的含有石斛石斛的组合物，用于减轻组合物施用于人体时的副作用，即使长期使用后也显示出较低的抗性。 构成：用于预防或治疗肾脏疾病的组合物含有0.001-10重量％的石斛提取物作为活性成分。 提取物是石斛石斛的C1-C6醇提取物。 C1-C6醇是甲醇或乙醇。 该组合物用于降低血清肌酐。 （附图标记）（AA）销售存活率（％）; （BB）石斛石斛

    진세노사이드 ２０(Ｓ)-알지3 또는 진세노사이드 ２０(Ｒ)-알지3의 함량비율이 증가된 가공 파낙스속 식물 추출물, 그 제조방법, 및 그 가공 파낙스속 식물 추출물을 포함하는 조성물
    32.
    发明公开
    진세노사이드 ２０(Ｓ)-알지3 또는 진세노사이드 ２０(Ｒ)-알지3의 함량비율이 증가된 가공 파낙스속 식물 추출물, 그 제조방법, 및 그 가공 파낙스속 식물 추출물을 포함하는 조성물 有权
    加工PANAX SPP 植物提取物，其具有增加的茚三酮20（S）-RG 3或茚三酮20（R）-RG 3的含量比例，其制备方法和包含其的组合物

    公开(公告)号：KR1020130093331A

    公开(公告)日：2013-08-22

    申请号：KR1020120014831

    申请日：2012-02-14

    Applicant: 한국과학기술연구원

    Inventor： 강기성 ,  함정엽 ,  김수남 ,  권학철 ,  정봉철 ,  이우정 ,  박순혜

    IPC: A61K36/258 ,  A61K31/704 ,  A61P35/00

    CPC classification number: A61K36/258 ,  A23L33/105 ,  A23L33/175 ,  A61K31/198 ,  A61K31/704 ,  A61K2236/333

    Abstract: PURPOSE: A processed ginseng extract is provided to contain a large amount of ginsenoside Rg3, Rg5, Rk1, and to selectively contain ginsenoside of 20 (S)-Rg3 or ginsenoside of 20 (R)-Rg3 depending on the desired effect. CONSTITUTION: A processed panax species plant extract is obtained by Maillard-browning a panax species plant extract with more than one amino acid selected from a group comprising arginine, alanine, and valine at 100-130 deg. C for 0.5-12 hours. The processed panax species plant extract is obtained by Maillard-browing the panax species plant extract with more than one amino acid selected from a group comprising leucine and glutamine at 100-130 deg. C for 0.5-12 hours. A pharmaceutical composition for anti-cancer, neuroprotection, inhibition of platelet aggregating, anti-oxidation, anti-inflammation, kidney protection, and anti-fatigue comprises the panax species plant extract.

    Abstract translation: 目的：提供加工的人参提取物以含有大量人参皂苷Rg3，Rg5，Rk1，并根据所需效果选择性地含有20（S）-Rg3或人参皂苷20（R）-Rg3的人参皂甙。 构成：在100-130度下，通过美拉德褐化具有多于一种氨基酸的选自精氨酸，丙氨酸和缬氨酸的氨基酸，获得经处理的藜属植物提取物。 C为0.5-12小时。 经加工的ax属植物提取物通过美拉德在100-130度下从含有亮氨酸和谷氨酰胺的组中选出的多于一种氨基酸的堇菜属植物提取物获得。 C为0.5-12小时。 用于抗癌，神经保护，抑制血小板聚集，抗氧化，抗炎，肾脏保护和抗疲劳的药物组合物包括豌豆种植物提取物。

    ＰＰＡＲ 작용 조절 질환의 예방, 개선 또는 치료용 조성물
    33.
    发明公开
    ＰＰＡＲ 작용 조절 질환의 예방, 개선 또는 치료용 조성물 无效
    用于预防，改善或治疗由PPAR治疗控制的疾病的组合物

    公开(公告)号：KR1020130047458A

    公开(公告)日：2013-05-08

    申请号：KR1020110112506

    申请日：2011-10-31

    Applicant: 한국과학기술연구원

    Inventor： 김수남 ,  이우정 ,  함정엽 ,  정유정 ,  황예란 ,  전영식 ,  윤구

    IPC: A61K36/8984 ,  A61K31/045 ,  A61K31/047 ,  A61P3/04

    CPC classification number: A61K36/8984 ,  A61K31/047 ,  A61K31/09 ,  A61K2236/333 ,  Y10S514/866 ,  Y10S514/909

    Abstract: PURPOSE: A composition containing Dendrobium moniliforme is provided to prevent, relieve, or treat PPAR activation regulation-related diseases including obesity, metabolic diseases, and cardiovascular diseases. CONSTITUTION: A composition for preventing or treating PPAR activation regulation-related diseases contains Dendrobium moniliforme as an active ingredient. A composition for health functional food for preventing or treating PPAR activation regulation-related diseases contains Dendrobium moniliforme as an active ingredient. Dendrobium moniliforme is used as pulverized Dendrobium moniliforme, a dried material thereof, or a crude extract prepared by using a solvent which is selected from water, C1-C4 alcohol, and a combination thereof. The C1-C4 alcohol is methanol or ethanol. Dendrobium moniliforme is also used as a fraction which is prepared from the crude extract using n-hexane, methylene chloride, or ethyl acetate. [Reference numerals] (AA) Relative value(%); (BB) No treatment group, Troglitazone; (CC) Example ; (DD) Example ; (EE) Example n-Hx; (FF) Example MC; (GG) Example EA; (HH) Example fr2; (II) Example fr3; (JJ) Example fr2-2; (KK) Example fr2-5; (LL) Example compound 1; (MM) Example compound 2; (NN) Example compound 3; (OO) Example compound 4

    Abstract translation: 目的：提供含有石斛仁的组合物，以预防，缓解或治疗PPAR活化调节相关疾病，包括肥胖，代谢疾病和心血管疾病。 构成：用于预防或治疗PPAR活化调节相关疾病的组合物含有石斛石斛作为活性成分。 用于预防或治疗PPAR活化调节相关疾病的健康功能性食品的组合物含有石斛兰作为活性成分。 石斛石斛被用作粉状石斛，其干燥物，或使用选自水，C1-C4醇及其组合的溶剂制备的粗提取物。 C1-C4醇是甲醇或乙醇。 石斛也用作由粗提取物使用正己烷，二氯甲烷或乙酸乙酯制备的级分。 （附图标记）（AA）相对值（％）; （BB）无治疗组，曲格列酮; （CC）实施例<1-1>; （DD）实施例<1-2>; （EE）实施例<2> n-Hx; （FF）实施例<2> MC; （GG）实施例 EA; （HH）实施例<3> fr2; （II）实施例<3> fr3; （JJ）实施例<3> fr2-2; （KK）实施例<3> fr2-5; （LL）实施例<3>化合物1; （MM）实施例3化合物2; （NN）实施例3化合物3; （OO）实例<3>化合物4

    신규한 니트치아 푸실라 균주 및 그 용도
    34.
    发明公开
    신규한 니트치아 푸실라 균주 및 그 용도 有权
    NITZSCHIA新闻 PUSILLA及其使用

    公开(公告)号：KR1020120031755A

    公开(公告)日：2012-04-04

    申请号：KR1020100093325

    申请日：2010-09-27

    Applicant: 한국과학기술연구원

    Inventor： 김수남 ,  최재영 ,  전병훈 ,  황재훈 ,  지민규 ,  이브라힘압드엘마키모하메드마터 ,  레다에이.아이.아부샤납

    IPC: C12N1/12 ,  C12P7/64 ,  C02F3/32 ,  C12R1/89

    CPC classification number: Y02E50/13 ,  C12N1/12 ,  C02F3/34 ,  C12P7/649 ,  C12R1/89

    Abstract: PURPOSE: Nitzschia cf. pusilla is provided to effectively produce bio diesel and to remove nitrogen and phosphorus from waste water. CONSTITUTION: A 28s rDNA of Nitzschia cf. pusilla contains a base sequence of sequence number 1. The lipid content is 48-60 wt%. The content of palmitic acid in the total fatty acid is 30-40 wt%. A composition for producing biodiesel contains the Nitzschia cf. pusilla strain, a culture thereof, or a dried product of the strain or culture. A microorganism formulation for treating waste water contains the strain, culture, or a mixture thereof.

    Abstract translation: 目的：Nitzschia参考 提供脓液以有效生产生物柴油并从废水中除去氮和磷。 构成：Nitzschia的28s rDNA参考 脓疮含有序列号1的碱基序列。脂质含量为48-60重量％。 总脂肪酸中棕榈酸的含量为30-40重量％。 用于生产生物柴油的组合物包含Nitzschia参考文献。 镰刀菌菌株，其培养物，或菌株或培养物的干燥产物。 用于处理废水的微生物制剂含有菌株，培养物或其混合物。

    퍼록시솜 증식자 활성화 수용체 알파/감마 이중 효능제인스틸벤 유도체 및 그 제조방법
    35.
    发明授权
    퍼록시솜 증식자 활성화 수용체 알파/감마 이중 효능제인스틸벤 유도체 및 그 제조방법 有权
    苯丙氨酸衍生物作为PPAR ALPHA / GAMMA双倍激动剂及其制备方法

    公开(公告)号：KR100894832B1

    公开(公告)日：2009-04-24

    申请号：KR1020070107775

    申请日：2007-10-25

    Applicant: 한국과학기술연구원

    Inventor： 함정엽 ,  안홍열 ,  박영희 ,  김수남 ,  이우정 ,  양현옥 ,  권학철

    IPC: C07C39/17 ,  C07C39/18 ,  C07C39/205

    Abstract: A stilbene derivatives as PPAR(peroxisome proliferator activation acceptor) alpha/gamma dual agonists is provided for treatment and prevention of obesity, diabetes, skin aging, skin wrinkle and skin hydration. A stilbene derivatives represented by the formula 1 is obtained by reacting a compound represented by the formula 2 and a compound represented by the formula 3. In the formula 1, 2 and 3, R^1 indicates an isoflavonoid group represented by the formula 1-a; R^2 is hydrogen, methyl, ethyl, tert-butyl, benzyl, methoxymethyl, trimethylsilyl, tert-butyldiphenylsilyl, tert-butyldimethylsilyl or triisopropylsilyl; R^3 shows -F, -CF3, -CH3 or -OCH3; A represents cis-, trans- isomers; m is an integer of 0~2; n is an integer of 1~5; p is integer of 0~2; and X shows a halogen atom.

    Abstract translation: 提供作为PPAR（过氧化物酶体增殖物激活受体）α/γ双重激动剂的二苯乙烯衍生物用于治疗和预防肥胖症，糖尿病，皮肤老化，皮肤皱纹和皮肤水合。 由式1表示的芪衍生物通过使式2表示的化合物与由式3表示的化合物反应而获得。在式1,2和3中，R 1表示由式1表示的异黄酮基， 一个; R 2是氢，甲基，乙基，叔丁基，苄基，甲氧基甲基，三甲基甲硅烷基，叔丁基二苯基甲硅烷基，叔丁基二甲基甲硅烷基或三异丙基甲硅烷基; R 3表示-F，-CF 3，-CH 3或-OCH 3; A代表顺式，反式异构体; m为0〜2的整数; n为1〜5的整数; p为0〜2的整数; X表示卤素原子。

    지피식물을 위한 옥상녹화장치
    39.
    发明授权
    지피식물을 위한 옥상녹화장치 有权
    屋顶录音机为巨型植物

    公开(公告)号：KR101858661B1

    公开(公告)日：2018-05-17

    申请号：KR1020150153903

    申请日：2015-11-03

    Applicant: 한국과학기술연구원

    Inventor： 이주영 ,  권학철 ,  김수남 ,  엄병헌 ,  이재욱 ,  박진수 ,  차진욱 ,  이민정

    IPC: A01G9/02 ,  A01G1/00 ,  A01G17/00

    Abstract: 본명세서에는도시옥상에지피식물및 약초생육을위한녹화장치가개시된다. 상기녹화장치는옥상바닥면에방수층을형성하고그 상부에배근층, 보수용저장배수층, 방근필터층및 지피식물용토양을순차적으로배치함으로써, 빗물흡수량을최대로증가시켜강우유출을지체시키고가뭄시 천천히지속적으로수분을공급하여도시가뭄현상을극복함으로써지피식물을장기간안정적으로생육할수 있는효과가있다.

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