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    6-0-METHYL ERYTHROMYCIN D AND PROCESS FOR MAKING
    32.
    发明申请
    6-0-METHYL ERYTHROMYCIN D AND PROCESS FOR MAKING 审中-公开
    6-0-甲基红霉素D及其制备方法

    公开(公告)号：WO1997019095A1

    公开(公告)日：1997-05-29

    申请号：PCT/US1996015772

    申请日：1996-10-01

    Applicant: ABBOTT LABORATORIES

    Inventor： ABBOTT LABORATORIES ,  LIU, Jih-Hua ,  CELEBUSKI, Joseph, E.

    IPC: C07H17/08

    CPC classification number: C07H17/08

    Abstract: An antibacterial compound is disclosed having formula (II), wherein R1 is loweralkyl or a pharmaceutically acceptable salt, ester or prodrug thereof, processes and intermediates useful in the preparation of the above compounds, as well as compositions containing the same and methods for their use.

    Abstract translation: 公开了具有式（II）的抗菌化合物，其中R 1是低级烷基或其药学上可接受的盐，酯或前药，可用于制备上述化合物的方法和中间体，以及含有它们的组合物及其使用方法 。

    TENSION RESPONSIVE PINCH VALVE
    33.
    发明申请
    TENSION RESPONSIVE PINCH VALVE 审中-公开
    张力响应的密封阀

    公开(公告)号：WO1997011296A1

    公开(公告)日：1997-03-27

    申请号：PCT/US1996014602

    申请日：1996-09-11

    Applicant: ABBOTT LABORATORIES

    Inventor： ABBOTT LABORATORIES ,  OSBORNE, Robert, S. ,  PIONTEK, Carl, J. ,  BUCK, Bradford, L. ,  FLEMING, Matthew, S. ,  WILSON, Grant, R. ,  PATTON, William, E. ,  ALEXANDER, Kathryn, E. ,  HARRIS, Jeremy, M. ,  LYON, William, F.

    IPC: F16K07/02

    CPC classification number: A61M39/288

    Abstract: A tension responsive pinch valve is made up of a combination of an elastically flexible pinch valve element and a length of flexible tubing having a section that is to be closed automatically by being distorted to the point of pinching or kinking and thus closing the lumen when the distorted section is not under longitudinal tension. The pinch valve element is associated longitudinally with the tubing section and preferably has two end portions connected by a shank portion. The end portions are attached to the tubing section at spaced-apart points longitudinally of the flexible tubing such that the length of the encompassed section is much longer than the shank portion of the pinch valve element. If the elastic yield strength of the shank portion is greater than the bend resistance of the flexible tubing, the encompassed section of the flexible tubing will be bent over to the point of occlusion when the section is not under tension but will allow the passage of fluid when longitudinal unkinking tension is applied.

    Abstract translation: 张力响应夹紧阀由弹性柔性夹管阀元件和一定长度的柔性管道的组合构成，该管状部件具有通过扭曲到捏合或扭结点并因此在管腔闭合时自动关闭的部分 扭曲部分不在纵向张力之下。 夹管阀元件与管道部分纵向连接，并且优选地具有通过柄部分连接的两个端部部分。 端部在柔性管的纵向上以间隔开的点附接到管部分，使得包围部分的长度比夹紧阀元件的柄部分长得多。 如果柄部分的弹性屈服强度大于柔性管的弯曲阻力，当该部分不处于张力下时，柔性管的包围部分将被弯曲到咬合点，但允许流体通过 当施加纵向不打滑张力时。

    VALVE CONSTRUCTION AND METHOD OF USE
    35.
    发明申请
    VALVE CONSTRUCTION AND METHOD OF USE 审中-公开
    阀门结构和使用方法

    公开(公告)号：WO1997004372A2

    公开(公告)日：1997-02-06

    申请号：PCT/US1996011862

    申请日：1996-07-18

    Applicant: ABBOTT LABORATORIES

    Inventor： ABBOTT LABORATORIES ,  ALCOCK, Alan, J. ,  PAN, Jeffrey, Y. ,  EGAN, Karen, A. ,  HUANG, Tung-Ming

    IPC: G05D07/00

    CPC classification number: F16K11/22 ,  Y10T137/7871

    Abstract: Embodiments described herein provide a valve construction. One embodiment comprises a first valve (12) and a second valve (14). A first fluid conveying conduit (16) fluidly conveying a first fluid is fluidly connected with the first valve (12). A second fluid conveying conduit (18) fluidly conveying a second fluid is fluidly connected with the second valve. A third fluid conveying conduit (22) is fluidly connected with the first valve (12) and the second valve (14). The first valve (12) is movable between a first position where first fluid flows between the first fluid conveying conduit and the third fluid conveying conduit, and a second position where first fluid does not flow between the first fluid conveying conduit and the third fluid conveying conduit. The second valve (14) is movable between a first position where the second fluid flows between the second fluid conveying conduit and the third fluid conveying conduit, and a second position where the second fluid does not flow between the second fluid conveying conduit and the third fluid conveying conduit.

    Abstract translation: 本文所述的实施例提供阀结构。 一个实施例包括第一阀（12）和第二阀（14）。 流体输送第一流体的第一流体输送导管（16）与第一阀（12）流体连接。 流体输送第二流体的第二流体输送管道（18）与第二阀流体连接。 第三流体输送管道（22）与第一阀（12）和第二阀（14）流体连接。 第一阀（12）可在第一流体在第一流体输送管道和第三流体输送管道之间流动的第一位置与第一流体不在第一流体输送管道和第三流体输送管道之间流动的第二位置之间移动 导管。 第二阀（14）可在第二流体在第二流体输送管道和第三流体输送管道之间流动的第一位置和第二流体不在第二流体输送管道和第三流体输送管道之间流动的第二位置之间移动 流体输送管道。

    ADENOSINE KINASE POLYNUCLEOTIDES
    38.
    发明申请
    ADENOSINE KINASE POLYNUCLEOTIDES 审中-公开
    腺嘌呤激酶多核苷酸

    公开(公告)号：WO1996040937A2

    公开(公告)日：1996-12-19

    申请号：PCT/US1996008097

    申请日：1996-05-31

    Applicant: ABBOTT LABORATORIES

    Inventor： ABBOTT LABORATORIES ,  COWART, Marlon, D. ,  HALBERT, Donald, N. ,  KERWIN, James, F., Jr. ,  MCNALLY, Teresa

    IPC: C12N15/54

    CPC classification number: C12N9/1205 ,  A61K38/00

    Abstract: The present invention provides an isolated and purified polynucleotide that encodes mammalian adenosine kinase, and to an isolated and purified adenosine kinase polypeptide. Human recombinant adenosine kinase and methods of using adenosine kinase polypeptides are also provided. Methods of making recombinant adenosine kinase using those polynucleotides and host cells transformed with those polynucleotides are also provided.

    Abstract translation: 本发明提供了分离和纯化的多核苷酸，其编码哺乳动物腺苷激酶，以及分离和纯化的腺苷激酶多肽。 还提供了人重组腺苷激酶和使用腺苷激酶多肽的方法。 还提供了使用那些多核苷酸和用这些多核苷酸转化的宿主细胞制备重组腺苷激酶的方法。

    MINERAL POWDERS WITH ENHANCED CHROMIUM SOLUBILITY AND PREPARATION METHODS THEREFOR
    40.
    发明申请
    MINERAL POWDERS WITH ENHANCED CHROMIUM SOLUBILITY AND PREPARATION METHODS THEREFOR 审中-公开
    具有提高铬溶解性的矿粉及其制备方法

    公开(公告)号：WO1996039871A1

    公开(公告)日：1996-12-19

    申请号：PCT/US1996008214

    申请日：1996-05-31

    Applicant: ABBOTT LABORATORIES

    Inventor： ABBOTT LABORATORIES ,  GOLIGHTLY, Danold, Wayne ,  SGONTZ, Donald, Lee, Jr. ,  KEDZIERSKI, Bogdan, Kazimierz ,  ABEL, Frank, Stanley ,  YAO, Benita, Co

    IPC: A23L01/304

    CPC classification number: A23L33/165

    Abstract: Process methods are described for combining compounds of mineral nutrients into chemically stable powder mixtures that notably preserve chromium in a soluble form conducive to both absorption and bioavailability. The methods include the compounds of minerals in preferred chemical forms, procedures for treatment of certain compounds to maintain solubility, appropriate sequences for combination of the compounds and other premix ingredients, and blending to provide an adequately homogeneous mixture. The methods provide premixes of minerals that support bioavailable chromium and that exhibit good stability, solubility, odor and color for addition to nutritional products. The stable chronium -III- complexes are prepared by complexing a Cr-III powder with a carboxylic acid. The nutritional powdered mixture comprises water to substantially resist formation of insoluble chronium compounds.

    Abstract translation: 描述了将矿物营养物的化合物组合成化学稳定的粉末混合物的方法，其特别是以可吸收的形式保存铬，这有助于吸收和生物利用度。 这些方法包括优选化学形式的矿物化合物，用于处理某些化合物以保持溶解性的方法，用于组合化合物和其它预混物成分的合适顺序，以及混合以提供足够均匀的混合物。 该方法提供了支持生物可利用铬的矿物质的预混物，并且对营养产品的添加表现出良好的稳定性，溶解性，气味和颜色。 通过使Cr-III粉末与羧酸络合来制备稳定的时间-III-络合物。 营养粉末混合物包含水以基本上抵抗不溶性时代化合物的形成。

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