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    31.
    发明专利
    未知

    公开(公告)号：DE4023576A1

    公开(公告)日：1992-01-30

    申请号：DE4023576

    申请日：1990-07-25

    Applicant: BASF AG

    Inventor： LADNER WOLFGANG ,  PRESSLER UWE ,  SIEGEL WOLFGANG

    IPC: C12N1/20 ,  C12N1/21 ,  C12N15/01 ,  C12P13/08 ,  C12R1/13 ,  C12R1/15

    Abstract: Described is a method for the preparation of microorganisms which have an elevated L-lysine production capability by mutation of microorganisms of the genuses Corynebacterium and Brevibacterium with known mutagens in a known manner, characterized in that strains of said genuses are mutated, selecting those wich are resistant to regenerative inhibition by 2-azido- epsilon -caprolactam.

    33.
    发明专利
    未知

    公开(公告)号：ES2141254T3

    公开(公告)日：2000-03-16

    申请号：ES94928365

    申请日：1994-09-16

    Applicant: BASF AG

    Inventor： BALKENHOHL FRIEDHELM ,  HAUER BERNHARD ,  LADNER WOLFGANG ,  PRESSLER UWE ,  NUBLING CHRISTOPH

    IPC: C12P13/02 ,  C12P41/00 ,  C12R1/38

    Abstract: PCT No. PCT/EP94/03102 Sec. 371 Date Mar. 11, 1996 Sec. 102(e) Date Mar. 11, 1996 PCT Filed Sep. 16, 1994 PCT Pub. No. WO95/08636 PCT Pub. Date Mar. 30, 1995A process for producing optically active primary and secondary amines from the corresponding racemates is characterised in that (a) a racemic amine is enantioselectively acylated in the presence of a hydrolase with an ester whose acid component bears a fluorine, nitrogen, oxygen or sulphur atom at the proximity of the carbonyl carbon atom; (b) the mixture of optically active amine and optically active acylated amine is separated so that an enantiomer of amine is produced; (c) if desired the other enantiomer of the amine is extracted from the acylated amine by amide cleavage.

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