公开(公告)号：US09085792B2

公开(公告)日：2015-07-21

申请号：US14238673

申请日：2012-08-30

Applicant: Bruno Colin ,  Marie-Pierre Montet

Inventor： Bruno Colin ,  Marie-Pierre Montet

IPC: C12Q1/24 ,  C12M1/22 ,  C12M1/00 ,  C12M1/26

CPC classification number: C12Q1/24 ,  C12M23/10 ,  C12M23/38 ,  C12M33/08

Abstract: The present invention relates to a method for inoculating at least one agar culture medium, contained in a Petri dish, with at least one sample likely to contain microorganisms. The method includes the steps of: providing at least one agar culture medium contained in a Petri dish; providing the sample likely to contain microorganisms in liquid form; performing at least one deposition of the liquid sample onto the lid of the Petri dish such that the liquid sample can be transferred from the lid to the agar culture medium; and spraying the liquid sample, initially deposited onto the cover, onto the agar culture medium by vibrating the Petri dish.

Abstract translation: 本发明涉及用至少一种可能含有微生物的样品接种培养皿中含有的至少一种琼脂培养基的方法。 该方法包括以下步骤：提供培养皿中所含的至少一种琼脂培养基; 提供样品可能含有液体形式的微生物; 将液体样品的至少一次沉积物执行到培养皿的盖上，使得液体样品可以从盖子转移到琼脂培养基中; 并通过振动培养皿将初始沉积到盖上的液体样品喷洒到琼脂培养基上。

公开(公告)号：US20140093428A1

公开(公告)日：2014-04-03

申请号：US14123145

申请日：2012-06-04

Applicant: Hélène Briand ,  Bruno Colin ,  Cécile Paris

Inventor： Hélène Briand ,  Bruno Colin ,  Cécile Paris

IPC: G01N33/53 ,  B29C43/46

CPC classification number: G01N33/5302 ,  B29C43/46 ,  G01N33/54386 ,  G01N33/558 ,  G01N33/56988

Abstract: The present invention relates to a device for performing an immunoassay, the device including a) a support, b) a porous matrix, fixed on the support, the matrix including (i) a liquid sample application area, (ii) a labeling area and (iii) at least one reaction area which includes a test results display area and a verification area, said liquid sample application area labeling area and reaction area being in fluid communication; the device including, at the verification area, at least a part of the porous matrix has pores with dimensions smaller than those of the labeled particles, such that at least a proportion of the labeled particles from the labeling area is stopped at said verification area forming a symbol which is visible or displayable for a user; and a method for manufacturing the device.

Abstract translation: 本发明涉及一种用于进行免疫测定的装置，该装置包括a）支撑体，b）固定在载体上的多孔基质，所述基质包括（i）液体样品施用区域，（ii）标记区域和 （iii）至少一个包括测试结果显示区域和验证区域的反应区域，所述液体样品应用区域标记区域和反应区域处于流体连通状态; 所述装置包括在验证区域处的多孔基质的至少一部分具有尺寸小于被标记颗粒尺寸的孔，使得至少一部分来自标记区域的标记颗粒在所述验证区域形成 对用户可见或可显示的符号; 以及该装置的制造方法。

公开(公告)号：US20130011566A1

公开(公告)日：2013-01-10

申请号：US13636196

申请日：2011-03-24

Applicant: Bruno Colin ,  Nathalie Simon

Inventor： Bruno Colin ,  Nathalie Simon

IPC: C12M1/22 ,  B05D3/00

CPC classification number: C12M23/10 ,  B01L3/508 ,  B01L2300/0851

Abstract: The present invention relates to a Petri dish, intended for receiving an agar culture medium for microorganisms, including a base receiving said culture medium and a lid capable of being positioned on the base, said base and said lid being substantially circular, said Petri dish being characterised in that the base includes at least one means intended to avoid the retraction of the culture medium, said means projecting and being positioned on the periphery of the base.

Abstract translation: 本发明涉及一种用于接收微生物的琼脂培养基的培养皿，包括接收所述培养基的基底和能够定位在基底上的盖，所述基部和所述盖基本上是圆形的，所述培养皿是 其特征在于，所述底座包括用于避免所述培养基回缩的至少一个装置，所述装置突出并定位在所述基部的周边上。

公开(公告)号：US20130004287A1

公开(公告)日：2013-01-03

申请号：US13609382

申请日：2012-09-11

Applicant: Bruno Colin ,  Yaneli lakimova ,  Kevin G. Ketsenberg ,  David M. Robbins ,  Stéphane Bellet

Inventor： Bruno Colin ,  Yaneli lakimova ,  Kevin G. Ketsenberg ,  David M. Robbins ,  Stéphane Bellet

IPC: B65G59/06 ,  B65G61/00

CPC classification number: C12M23/48 ,  C12M23/10 ,  G01N35/04 ,  G01N2035/042 ,  G01N2035/0425

Abstract: A holding structure for holding a plurality of culture plates in a stacked arrangement includes a feature for de-nesting the bottom culture plate from the plate above it. The de-nesting feature is preferably a structure which urges a plate to move laterally relative to the plate above it. The de-nesting of the bottom culture plate from the adjacent culture plate facilitates withdrawal of the bottom culture plate from the base via a robotic plate transfer mechanism. The de-nesting feature can be entirely passive, such as ramps formed in the base of the holding structure.

Abstract translation: 用于保持多个培养板的堆叠布置的保持结构包括用于将底部培养板从其上方的板上嵌套的特征。 去嵌套特征优选地是一种促使板相对于其上方的板横向移动的结构。 来自相邻培养板的底部培养板的解嵌有助于通过机器人板转移机构将底部培养板从基底中取出。 去嵌套特征可以是完全无源的，例如形成在保持结构的基部中的斜面。

公开(公告)号：US07537730B2

公开(公告)日：2009-05-26

申请号：US10362873

申请日：2001-08-27

Applicant: Bruno Colin ,  Cécile Paris ,  Bernard Limon ,  Patrick Broyer ,  Charles Rogers

Inventor： Bruno Colin ,  Cécile Paris ,  Bernard Limon ,  Patrick Broyer ,  Charles Rogers

IPC: F16K35/00 ,  B01L11/00 ,  G01N21/00 ,  F17D1/16

CPC classification number: B01L3/502738 ,  B01L2200/10 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2400/0638 ,  B01L2400/0655 ,  G01N2035/00247 ,  G01N2035/00257 ,  Y10T137/0396

Abstract: A reaction card (1) having a body, a front surface (62) and a rear surface (63) defined by an edge (68), at least one inlet (2, 3, 4 and/or 5) and at least one outlet (7and/or 8), connected by a network of channels (64) constituting at least one reaction path for at least one fluid which is directed via valves (11to 36 and/or 61); each valve includes a flexible film (67) which can be deformed to allow fluid passage, the film being fixed on the card's rear surface at a peripheral indentation of an assembly of channels associated with the valve; the card includes channels flush with at least one of its surfaces, the channels being of two different cross-sections, a small cross-section serving as a reaction compartment; each front or rear surface is delimited by at least one film (48, 49, 65, 66 and/or 67).

Abstract translation: 具有主体的反应卡（1），由边缘（68）限定的前表面（62）和后表面（63），至少一个入口（2,3,4和/或5）和至少一个 出口（7和/或8）通过构成用于至少一个通过阀（11至36和/或61）的流体的至少一个反应路径的通道网络（64）连接; 每个阀包括柔性膜（67），其可以变形以允许流体通过，所述膜被固定在卡的后表面上与阀相关联的通道组件的周边凹陷处; 卡包括与其表面中的至少一个平齐的通道，通道具有两个不同的横截面，小的横截面用作反应室; 每个前表面或后表面由至少一个膜（48,49,65,66和/或67）限定。

公开(公告)号：US20080041259A1

公开(公告)日：2008-02-21

申请号：US10585356

申请日：2005-01-20

Applicant: Patrick Broyer ,  Bruno Colin ,  Denis Roller

Inventor： Patrick Broyer ,  Bruno Colin ,  Denis Roller

IPC: F42C19/12 ,  B05D1/02 ,  B05D1/18 ,  B05D1/36 ,  B32B27/00

CPC classification number: F16K99/0001 ,  F15B15/19 ,  F15C5/00 ,  F16K99/0015 ,  F16K99/0067 ,  F16K2099/008 ,  F42B3/04 ,  F42C19/06 ,  F42C19/12 ,  Y10T428/261 ,  Y10T428/31

Abstract: The invention relates to a microsystem and a method for fabricating a microsystem. The pyrotechnic microsystem (7, 1′) comprises a substrate having at least two separate electrical initiation zones, each of which provides separate electrical initiation of a pyrotechnic material deposited on the substrate. This microsystem (7, 1′) is characterized in that the same pyrotechnic material deposit (721, 721′, 13) covers both initiation zones, said deposit (721, 721′, 13) produced on the substrate having a thickness sufficiently small for the initiation of the pyrotechnic material in the initiation zone to remain localized and not propagate to the other initiation zone, but sufficient to generate a specific gas quantity.

Abstract translation: 本发明涉及微系统和微系统的制造方法。 烟火微系统（7,1'）包括具有至少两个分开的电引发区的衬底，每个电引发区提供沉积在衬底上的烟火材料的单独的电引发。 该微系统（7,1'）的特征在于，相同的烟火材料沉积物（721,721'，13）覆盖两个起始区域，所述沉积物（721,721'，13）在基板上产生的厚度足够小， 起始区域中的烟火材料的起始保持局部化并且不会传播到另一个起始区，但足以产生特定的气体量。

公开(公告)号：US20050257829A1

公开(公告)日：2005-11-24

申请号：US10531947

申请日：2003-11-18

Applicant: Patrick Broyer ,  Bruno Colin ,  Denis Roller

Inventor： Patrick Broyer ,  Bruno Colin ,  Denis Roller

IPC: B81B1/00 ,  B81B3/00 ,  F15C5/00 ,  F16K99/00 ,  H01H1/00 ,  H01H39/00 ,  F16K17/40

CPC classification number: F16K99/0001 ,  F15C5/00 ,  F16K99/0015 ,  F16K99/0067 ,  F16K2099/008 ,  H01H1/0036 ,  H01H39/00 ,  Y10T137/1647

Abstract: The invention concerns the technical field of micro-actuators used for mechanical, chemical, electrical or thermal functions in microsystems, for microelectronic applications such as chips, or biomedical functions such as microfluidics integrating cards. the invention concerns a micro-actuator comprising a so-called main chamber, made in a solid support and containing a so-called main pyrotechnic charge, said main chamber being sealed and delimited by solid support walls and by a deformable membrane, such that the gases emitted by the combustion of the main pyrotechnic charge, enable the volume of said chamber to be increased by deforming said membrane while maintaining intact the solid walls of the main chamber. The invention is characterized in that it comprises means for evacuating the gases from the main chamber.

Abstract translation: 本发明涉及用于微系统中的机械，化学，电或热功能的微致动器的技术领域，用于微电子应用如芯片或生物医学功能，例如集成卡的微流体。 本发明涉及一种微致动器，其包括所谓的主室，其形成为固体支撑并且包含所谓的主要烟火充电，所述主室由实心支撑壁和可变形膜密封并界定，使得 通过主烟火装置的燃烧发出的气体使得通过使所述膜变形而使所述室的体积增加，同时保持主室的固体壁完好无损。 本发明的特征在于其包括用于从主室排出气体的装置。

公开(公告)号：US06632287B1

公开(公告)日：2003-10-14

申请号：US09529662

申请日：2000-04-18

Applicant: Bruno Colin ,  Marie Privat

Inventor： Bruno Colin ,  Marie Privat

IPC: B08B702

CPC classification number: A61L2/04

Abstract: The invention provides a method and device for decontaminating a contaminated hollow metal needle having electrical wires attached to the needle which heat cleaning fluid dispensed into the needle.

Abstract translation: 本发明提供了一种用于净化污染的中空金属针的方法和装置，其具有附接到针上的电线，其中分配到针中的热清洁流体。

公开(公告)号：US06589790B1

公开(公告)日：2003-07-08

申请号：US09194726

申请日：1998-12-02

Applicant: Bruno Colin ,  Cécile Jaravel

Inventor： Bruno Colin ,  Cécile Jaravel

IPC: C12M116

CPC classification number: B01L3/5025 ,  B01L3/50273 ,  B01L2200/027 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2400/049 ,  G01N1/14 ,  G01N2001/2078 ,  G01N2035/00148 ,  Y10T436/111666 ,  Y10T436/119163 ,  Y10T436/25 ,  Y10T436/2575

Abstract: Device for filling, with a liquid medium (1), an analysis card (2) comprising a body (3) in which at least one reading cavity (3a) is formed, and an orifice (4) communicating with the cavity via at least one internal channel (7), with an external conduit (9) communicating with the orifice, this device comprising an evacuation device (50). It comprises: a connecting device (11) including on one side a joining piece (12) for leaktight and removable coupling to the free end (9a) of the open external conduit, and communicating directly on the other side with the evacuation device (50); a device (34) for closing and re-opening the external conduit.

Abstract translation: 用于用液体介质（1）填充分析卡（2）的装置，包括形成有至少一个读腔（3a）的主体（3），以及至少与空腔连通的孔口（4） 一个内部通道（7），具有与孔口连通的外部导管（9），该装置包括排气装置（50）。 它包括：一个连接装置（11），其一端包括接合件（12），用于密封和可拆卸地连接到开放的外部导管的自由端（9a），并且在另一侧与排气装置（50 ）; 用于关闭和重新打开外部导管的装置（34）。

公开(公告)号：US06263743B1

公开(公告)日：2001-07-24

申请号：US09202618

申请日：1998-12-18

Applicant: Bruno Colin ,  Cécile Jaravel

Inventor： Bruno Colin ,  Cécile Jaravel

IPC: G01N100

CPC classification number: B01L3/0275 ,  G01N35/1095

Abstract: A device for transferring a liquid sample drawn by suction, through a wall having an orifice, the device including a conduit, a plunger sealingly sliding in the conduit, and a rod controlling the plunger. The device includes a joining piece extending the conduit, with an outer cross-section adapted to fit in the aperture, for example sealing it, with close working clearance required for inserting the joining piece in the orifice, the joining piece being arranged to be separated from the conduit once it is engaged in the orifice, and to seal the orifice, when or once the joining piece engaged in the orifice is separated from the conduit.

Abstract translation: 一种用于传送通过抽吸抽吸的液体样品的装置，通过具有孔口的壁，所述装置包括导管，在所述导管中密封地滑​​动的柱塞以及控制所述柱塞的杆。 该装置包括延伸导管的接合件，其外部横截面适于安装在孔中，例如密封，具有将接合件插入孔中所需的紧密工作间隙，接合件被布置成分离 从导管一旦接合在孔中并且密封孔口，何时或一旦接合在孔中的接合件与导管分离。