公开(公告)号：US09057825B2

公开(公告)日：2015-06-16

申请号：US13520033

申请日：2011-10-07

Applicant: David Erickson ,  Yih-Fan Chen

Inventor： David Erickson ,  Yih-Fan Chen

IPC: G02B6/00 ,  G02B6/12 ,  B82Y20/00 ,  G02B6/122 ,  G02F1/025 ,  B01L3/00 ,  G01N15/10 ,  G01N15/00

CPC classification number: G02B6/12 ,  B01L3/502761 ,  B01L2200/0668 ,  B01L2300/0654 ,  B01L2400/0454 ,  B82Y20/00 ,  G01N15/10 ,  G01N2015/0038 ,  G01N2015/0053 ,  G02B6/1225 ,  G02B2006/12061 ,  G02B2006/12147 ,  G02F1/025

Abstract: A plurality of photonic crystal resonator optical trapping apparatuses and a plurality optical trapping methods using the plurality of photonic crystal resonator optical trapping apparatuses include located and formed over a substrate a photonic waveguide that is coupled (i.e., either separately coupled or integrally coupled) with a photonic crystal resonator. In a particular embodiment, the photonic waveguide and the photonic crystal resonator comprise a monocrystalline silicon (or other) photonic material absent any chemical functionalization. In another particular embodiment, the photonic waveguide and the photonic crystal resonator comprise a silicon nitride material which when actuating the photonic crystal resonator optical trapping apparatus with a 1064 nanometer resonant photonic radiation wavelength (or other resonant photonic radiation wavelength in a range from about 700 to about 1200 nanometers) provides no appreciable heating of an aqueous sample fluid that is analyzed by the photonic crystal resonator optical trapping apparatus.

Abstract translation: 使用多个光子晶体振荡器光学捕获装置的多个光子晶体谐振器光学捕获装置和多个光学俘获方法包括在衬底上定位并形成光子波导，该光子波导耦合（即，单独耦合或整体耦合）与 光子晶体谐振器。 在特定实施例中，光子波导和光子晶体谐振器包括不存在任何化学官能化的单晶硅（或其它）光子材料。 在另一特定实施例中，光子波导和光子晶体谐振器包括氮化硅材料，当氮化硅材料致动具有1064纳米共振光子辐射波长（或其他谐振光子辐射波长在约700至 约1200纳米）对由光子晶体谐振器光学捕获装置分析的水样品流体没有明显的加热。

公开(公告)号：US09057099B2

公开(公告)日：2015-06-16

申请号：US13124296

申请日：2009-10-14

Applicant: David Erickson ,  Yun Suk Huh ,  Carl A. Batt ,  Adam Joseph Lowe

Inventor： David Erickson ,  Yun Suk Huh ,  Carl A. Batt ,  Adam Joseph Lowe

IPC: C12Q1/68 ,  C12P19/34 ,  C07H21/00 ,  C07H21/02 ,  C07H21/04 ,  B01F13/00 ,  B01L3/00 ,  G01N21/65

CPC classification number: C12Q1/6827 ,  B01F13/0076 ,  B01L3/50273 ,  B01L3/502761 ,  B01L2300/0636 ,  B01L2300/0654 ,  B01L2300/0809 ,  B01L2300/0829 ,  B01L2300/0887 ,  B01L2400/0415 ,  B01L2400/0424 ,  C12Q1/6862 ,  C12Q2565/632 ,  G01N21/658 ,  C12Q2563/137 ,  C12Q2531/137

Abstract: A method for detecting target nucleic acids such as SNPs is provided. The method comprises performing a ligase detection reaction (LDR), performing surface enhanced Raman scattering (SERS) on the LDR, and analyzing the outcome of the LDR using analysis and/or quantification of the SERS by detecting an emitted Raman signature. The LDR-SERS method can be used for sensitive and specific detection of any nucleic acid sequence of interest. A microfluidic SERS detection device is also provided. The device comprises electrokinetically active microwells for mixing and concentrating analytes and in which analytes can be quantified. The device can be used for performing the LDR-SERS method in optofluidic chip format.

Abstract translation: 提供了检测目标核酸如SNP的方法。 该方法包括在LDR上进行连接酶检测反应（LDR），进行表面增强拉曼散射（SERS），并通过检测发射的拉曼特征来分析和/或定量SERS来分析LDR的结果。 LDR-SERS方法可用于感兴趣的任何核酸序列的敏感和特异性检测。 还提供了微流体SERS检测装置。 该装置包括用于混合和浓缩分析物的电动活性微孔，并且其中可分析物被量化。 该器件可用于以光流体芯片格式执行LDR-SERS方法。

公开(公告)号：US08954538B2

公开(公告)日：2015-02-10

申请号：US12650171

申请日：2009-12-30

Applicant: David Erickson ,  Marcus Kellerman ,  Xuemin Chen ,  Vladimir Silyaev

Inventor： David Erickson ,  Marcus Kellerman ,  Xuemin Chen ,  Vladimir Silyaev

IPC: G06F15/16 ,  H04N21/61 ,  H04N21/236 ,  G06F17/30 ,  H04N21/435 ,  H04N21/4782 ,  H04N21/658 ,  H04L12/28 ,  H04N7/173 ,  H04N21/6377 ,  H04N21/235

CPC classification number: H04N21/4782 ,  G06F17/30899 ,  G06F17/30902 ,  H04L12/2834 ,  H04L67/02 ,  H04L67/04 ,  H04L67/28 ,  H04N7/17318 ,  H04N21/2335 ,  H04N21/2343 ,  H04N21/235 ,  H04N21/236 ,  H04N21/23614 ,  H04N21/2393 ,  H04N21/2402 ,  H04N21/25825 ,  H04N21/435 ,  H04N21/4622 ,  H04N21/6125 ,  H04N21/6175 ,  H04N21/6377 ,  H04N21/6405 ,  H04N21/658 ,  H04N21/8456

Abstract: A method and/or system are described in which a server communicatively coupled with a set-top-box (STB) may predict a location of a pointer on a web browser running on the STB. The server may render the pointer based on the predicted pointer location. The server may send the rendered pointer to the STB, wherein the STB may composite a web page on the web browser based on the rendered pointer. The server may be synchronized with the STB based on event information received by the server from the STB such as, for example, keystroke events, click event, or other like event. The prediction of the pointer location may be based on actual pointer location information provided by the STB. A predetermined number of pointer locations may be predicted based on an actual pointer location and/or on a latency of a connection between the server and the STB.

Abstract translation: 描述了与机顶盒（STB）通信耦合的服务器可以预测在STB上运行的web浏览器上的指针的位置的方法和/或系统。 服务器可以基于预测的指针位置来渲染指针。 服务器可以将所渲染的指针发送到STB，其中STB可以基于所渲染的指针来组合web浏览器上的网页。 服务器可以基于STB从服务器接收的事件信息与STB同步，例如按键事件，点击事件或其他类似事件。 指针位置的预测可以基于由STB提供的实际指针位置信息。 可以基于实际的指针位置和/或服务器和STB之间的连接的延迟来预测预定数量的指针位置。

公开(公告)号：US08861904B2

公开(公告)日：2014-10-14

申请号：US13504297

申请日：2010-10-27

Applicant: David Erickson ,  Aram J. Chung ,  Erica E. Jung

Inventor： David Erickson ,  Aram J. Chung ,  Erica E. Jung

IPC: G02B6/26 ,  G01N21/77 ,  G02B6/35 ,  G02B6/032

CPC classification number: G01N21/7746 ,  G02B6/354 ,  G02B2006/0325

Abstract: A reconfigurable optofluidic apparatus includes a microfluidic chip including a microfluidic channel further including an inlet for a liquid core waveguide fluid; a channel pathway for the liquid core waveguide fluid; a plurality of non-core waveguide fluid inlets; a switching chamber having a larger cross sectional area than the channel pathway; and an outlet for the liquid core waveguide fluid and non-core waveguide fluid, further including a plurality of non-liquid core waveguides disposed in the switching chamber. Light input to the apparatus propagates in the liquid core/liquid cladding (liquid) waveguide. The path of the liquid waveguide can be steered in a region of the apparatus over one of the non-liquid core waveguides such that the light is end-fire- or evanescently-coupled into the non-liquid core waveguide and output therefrom or between two of the non-liquid core waveguides and not coupled or output. Associated optofluidic switching methods are disclosed.

Abstract translation: 可重构光流体装置包括微流体芯片，其包括微流体通道，其还包括用于液芯波导流体的入口; 用于液芯波导流体的通道路径; 多个非芯波导流体入口; 开关室具有比通道路径更大的横截面面积; 以及用于液芯波导流体和非芯波导流体的出口，还包括设置在开关室中的多个非液体芯波导。 输入到设备的光在液芯/液体包层（液体）波导中传播。 液体波导的路径可以在非液体核心波导之一上的设备的区域中被引导，使得光被端火或ev逝耦合到非液体芯波导中并从其输出或两者之间输出 的非液体芯波导，并且不耦合或输出。 公开了相关的光流控开关方法。

公开(公告)号：US20120216232A1

公开(公告)日：2012-08-23

申请号：US13115035

申请日：2011-05-24

Applicant: Sherman (Xuemin) Chen ,  David Erickson ,  Vladimir Silyaev ,  Alan Trerise ,  Marcus C. Kellerman

Inventor： Sherman (Xuemin) Chen ,  David Erickson ,  Vladimir Silyaev ,  Alan Trerise ,  Marcus C. Kellerman

IPC: H04N7/173

CPC classification number: H04N21/234336 ,  H04N21/2368 ,  H04N21/4782 ,  H04N21/6581

Abstract: A gateway includes a communications interface and processing circuitry and establishes communications with at least one service provider device and with a serviced client device. The gateway receives serviced client device display structure instructions from a cloud server. The gateway then receives first streamed content from the cloud server, the first streamed content comprising images of an Internet session hosted by the cloud server and having a video program hole formed therein. The gateway receives second streamed content from the cloud server, the second streamed content comprising a video program corresponding to the video program hole of the first streamed content. Based upon the serviced client device display structure instructions, the gateway combines the first streamed content with the second streamed content to form merged streamed content and transmits the merged streamed content to the serviced client device. The client device may alternately receive and merge the video streams.

Abstract translation: 网关包括通信接口和处理电路，并建立与至少一个服务提供商设备和服务的客户端设备的通信。 网关从云服务器接收服务的客户端设备显示结构指令。 然后，网关从云服务器接收第一流传输的内容，第一流传输的内容包括由云服务器主持并在其中形成视频节目孔的因特网会话的图像。 网关从云服务器接收第二流内容，第二流内容包括对应于第一流内容的视频节目孔的视频节目。 基于服务的客户端设备显示结构指令，网关将第一流传输的内容与第二流内容相结合，以形成合并的流内容，并将合并的流式内容传输到服务客户端设备。 客户端设备可以交替地接收和合并视频流。

公开(公告)号：US20120196376A1

公开(公告)日：2012-08-02

申请号：US13391508

申请日：2010-08-20

Applicant: Seung-min Park ,  Yun Suk Huh ,  David Erickson ,  Harold G. Craighead

Inventor： Seung-min Park ,  Yun Suk Huh ,  David Erickson ,  Harold G. Craighead

IPC: G01N33/48 ,  G01N27/447 ,  B29C43/44 ,  H01L27/146 ,  G01J3/44 ,  B01L3/00 ,  B29C59/02 ,  B82Y5/00 ,  B82Y40/00

CPC classification number: G01N21/658 ,  B01D67/0088 ,  B01D71/70 ,  B01D2323/283 ,  B01L3/502707 ,  B01L3/502761 ,  B01L2200/0663 ,  B01L2300/0816 ,  B01L2300/0896 ,  B01L2300/123 ,  B01L2400/0421 ,  B81B2201/058 ,  B81C1/00071 ,  B82Y30/00 ,  G01N33/48721

Abstract: A method is provided for fabricating a nanochannel. The method comprises providing a microchannel and controlling collapse of the microchannel so that it collapses to form a nanochannel of desired dimensions. The method employs a collapsible, flexible material such as the elastomer polydimethylsiloxane (PDMS) to form the nanochannel. A master is provided that is configured to have geometric conditions that promote a desired frequency of microchannel collapse. A collapsible material having a stiffness that also promotes a desired frequency of microchannel collapse is molded on the master. The molded collapsible material is removed from the master and bonded to a base, thereby forming the microchannel, which then collapses (or is collapsed) to form the nanochannel of desired dimensions. Nanofluidic and microfluidic devices comprising complex nanochannel structures and micro to nanochannel transitions are also provided.

Abstract translation: 提供了制造纳米通道的方法。 该方法包括提供微通道并控制微通道的塌陷，使得其塌缩以形成具有期望尺寸的纳米通道。 该方法采用可折叠的柔性材料，例如弹性体聚二甲基硅氧烷（PDMS）以形成纳米通道。 提供了一个主设备，其配置为具有促进微通道倒塌的期望频率的几何条件。 在主体上模制具有也促进所需频率的微通道塌陷的刚度的可折叠材料。 模制的可折叠材料从主体中取出并结合到基底上，从而形成微通道，然后将其收缩（或折叠）以形成所需尺寸的纳米通道。 还提供了包括复杂纳米通道结构和微到纳通道转换的纳流体和微流体装置。

公开(公告)号：US08077309B2

公开(公告)日：2011-12-13

申请号：US11668083

申请日：2007-01-29

Applicant: Gordon C. Brown ,  Michael Burka ,  Brian Cranton ,  David Erickson ,  James Grassi ,  Matthew Patrick Hammond ,  Maximillan Ben Shaffer ,  Pierre Villeneuve

Inventor： Gordon C. Brown ,  Michael Burka ,  Brian Cranton ,  David Erickson ,  James Grassi ,  Matthew Patrick Hammond ,  Maximillan Ben Shaffer ,  Pierre Villeneuve

IPC: G01J3/44

CPC classification number: G01N21/65 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0262 ,  G01J3/0286 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/26 ,  G01J3/36 ,  G01J3/44 ,  G01J2003/1269 ,  G01N2021/1793 ,  G01N2021/8416 ,  G01N2201/0245 ,  G01N2201/067

Abstract: An optical apparatus for measurement of industrial chemical processes. The analyzer uses Raman scattering and performs measurement of chemical concentrations in continuous or batch processes. The analyzer operates at a standoff distance from the analyte (or analytes) and can measure concentrations through an optical port, facilitating continuous, non-destructive, and non-invasive analysis without extracting the analyte or analytes from the process. The analyzer can measure one or several solid, liquid, or gaseous analytes, or a mixture thereof.

Abstract translation: 一种用于测量工业化学工艺的光学装置。 分析仪使用拉曼散射，并在连续或间歇过程中进行化学浓度的测量。 分析仪与分析物（或分析物）隔开距离，并且可以通过光学端口测量浓度，有助于连续，非破坏性和非侵入性分析，而无需从该过程中提取分析物或分析物。 分析仪可以测量一种或多种固体，液体或气体分析物或其混合物。

公开(公告)号：US20110162023A1

公开(公告)日：2011-06-30

申请号：US12649998

申请日：2009-12-30

Applicant: Marcus Kellerman ,  Xuemin Chen ,  Vladimir Silyaev ,  David Erickson

Inventor： Marcus Kellerman ,  Xuemin Chen ,  Vladimir Silyaev ,  David Erickson

IPC: H04N7/173

CPC classification number: H04N21/6581 ,  H04N21/23424 ,  H04N21/25841 ,  H04N21/2668 ,  H04N21/4622 ,  H04N21/4782 ,  H04N21/812

Abstract: A device (e.g., a server) retrieves a web page based on a request from another device, for example, a set-top-box (STB). The server determines advertising content and/or web page content to deliver to the STB. The server renders and/or encodes the advertising content and the web page content and communicates the content to the STB. The content is decoded and/or displayed by the STB. The advertising content may be determined based on television viewing, recording and/or web browsing via the STB. The advertising content may be determined based on location information and/or user information from a service provider the STB and/or from user input. Advertising may be inserted within a splash screen, a plug-in window, and/or an area within the web page. Web page advertising may be replaced, blocked and/or modified based on user information. The determined advertising may be communicated to the STB prior to communicating a plug-in.

Abstract translation: 设备（例如，服务器）基于来自另一设备（例如机顶盒（STB））的请求来检索网页。 服务器确定要发送给STB的广告内容和/或网页内容。 服务器呈现和/或编码广告内容和网页内容，并将内容传达给STB。 内容由STB解码和/或显示。 可以基于经由STB的电视观看，记录和/或网页浏览来确定广告内容。 可以基于来自服务提供商STB和/或来自用户输入的位置信息和/或用户信息来确定广告内容。 广告可以插入到启动屏幕，插件窗口和/或网页内的区域中。 可以根据用户信息替换，阻止和/或修改网页广告。 所确定的广告可以在通信插件之前传送到STB。

公开(公告)号：US07641226B2

公开(公告)日：2010-01-05

申请号：US11591104

申请日：2006-11-01

Applicant: H{dot over (a)}kan Sundmark ,  Jamison Pexton ,  David Erickson

Inventor： H{dot over (a)}kan Sundmark ,  Jamison Pexton ,  David Erickson

IPC: B60R21/16

CPC classification number: B60R21/207 ,  B60R21/201 ,  B60R21/2342 ,  B60R21/26 ,  B60R21/261 ,  B60R2021/162

Abstract: A side airbag module for use in a motor vehicle. The module includes a gas generator attached to a folded airbag. The folded airbag unfolds into an interior of the motor vehicle when the gas generator is activated. A large guide fin is disposed within an interior of the airbag such that the airbag is disposed around the guide fin. The guide fin is connected to a component attached to the motor vehicle.

Abstract translation: 用于机动车辆的侧面安全气囊模块。 模块包括附接到折叠的气囊的气体发生器。 当气体发生器被激活时，折叠的气囊展开到机动车辆的内部。 在气囊的内部设置有大的引导翅片，使得气囊被布置在引导翅片周围。 引导翅片连接到附接到机动车辆的部件。

公开(公告)号：US20090032730A1

公开(公告)日：2009-02-05

申请号：US12143952

申请日：2008-06-23

Applicant: David Erickson ,  Sudeep Mandal

Inventor： David Erickson ,  Sudeep Mandal

IPC: G01N21/01

CPC classification number: G01N30/58 ,  B01L3/50273 ,  B01L3/502761 ,  B01L2300/0838 ,  B01L2400/0454 ,  G01N2030/285 ,  G01N2030/582 ,  G02B6/02328 ,  G02B6/02347 ,  G02B6/02385

Abstract: An optical chromatography system employs fluid filled hollow core fibers, such as photonic crystal fibers (PCFs), which confine an incident optical beam from a laser, for example, in the core and cause separation of particles in the fluid along the length of the PCF. The incident optical beam is confined in the fluid filled core of the PCF by a periodic lattice of air capillaries surrounding the core. The lattice either creates a lower refractive index in the cladding than in the fluid filled core or creates a ID photonic bandgap structure where the guiding is accomplished by surrounding the fluid filled core with a periodically changing array of dielectric constant which prohibits radial dilution of the optical energy over a range of wavelengths through photonic bandgap effects.

Abstract translation: 光学色谱系统采用流体填充的中空芯纤维，例如光子晶体纤维（PCF），其将来自激光器的入射光束例如限制在芯中，并且沿着PCF的长度导致流体中的颗粒分离 。 入射光束通过围绕芯的空气毛细管的周期性晶格限制在PCF的流体填充芯中。 晶格或者在流体填充芯中产生较低的折射率，或者产生ID光子带隙结构，其中引导是通过周期性地改变介电常数阵列来实现的，该阵列阻止了光学器件的径向稀释 通过光子带隙效应在一定范围的波长上的能量。