公开(公告)号：WO1995020345A1

公开(公告)日：1995-08-03

申请号：PCT/US1995001112

申请日：1995-01-27

Applicant: EP TECHNOLOGIES, INC.

Inventor： EP TECHNOLOGIES, INC. ,  SWANSON, David, K. ,  PANESCU, Dorin

IPC: A61B05/04

CPC classification number: A61B5/6855 ,  A61B5/0422 ,  A61B5/0536 ,  A61B5/6858 ,  A61B18/00 ,  A61B18/1492 ,  A61B2562/0209 ,  A61B2562/043

Abstract: Systems (10) for examining heart tissue morphology deploy one or more electrodes (38) into the heart in contact with endocardial tissue. The systems transmit electrical current from the electrodes (38) in paths through the contacted endocardial tissue. Based upon these current transmissions, the systems derive the electrical characteristics of tissue lying in the path. This electrical characteristc can be directly correlated to tissue morphology. The systems maximize surface contact with endocardial tissue, while minimizing contact with the surrounding blood pool, to obtain accurate tissue electrical characteristic measurements.

Abstract translation: 用于检查心脏组织形态的系统（10）将一个或多个电极（38）部署到与心内膜组织接触的心脏中。 该系统在通过所接触的心内膜组织的路径中从电极（38）传输电流。 基于这些当前传输，系统导出位于路径中的组织的电特性。 这种电学特征可以直接与组织形态相关。 系统最大限度地与心内膜组织的表面接触，同时最小化与周围血液池的接触，以获得精确的组织电特征测量。

公开(公告)号：WO1995010978A1

公开(公告)日：1995-04-27

申请号：PCT/US1994011758

申请日：1994-10-14

Applicant: EP TECHNOLOGIES, INC.

Inventor： EP TECHNOLOGIES, INC. ,  FLEISCHMAN, Sidney, D. ,  SWANSON, David, K. ,  HOUSER, Russell, A. ,  AMIRANA, Omar

IPC: A61B05/04

CPC classification number: A61B18/1492 ,  A61B2017/00101 ,  A61B2017/00455 ,  A61B2018/1417 ,  A61B2018/1497 ,  A61B2090/065 ,  A61N1/0565 ,  A61N1/40

Abstract: This invention is a multiple electrode array for ablating tissue that carries at least two electrode segments (26, 27, 28, 29) that are circumferentially spaced form each other. Insulation (30) electrically isolates the separated electrode segments from each other. Signal wires (19) attached to the separated electrode segments convey ablating energy independently to the separated electrode segments. Because of its segmented structure, the array can place only one of the electrode segments in contact with tissue at one time. Because each segment is electrically isolated, and because each segment is independently served by its own signal wire, a physician can operate an ablation energy generator to selectively channel the ablation energy only to the segment actually contacting the tissue.

Abstract translation: 本发明是一种用于烧伤组织的多电极阵列，其携带彼此周向隔开的至少两个电极段（26,27,28,29）。 绝缘（30）将分离的电极段彼此电隔离。 附接到分离的电极段的信号线（19）独立地传送消融能量到分离的电极段。 由于其分段结构，阵列可以一次只能将一个电极段与组织接触。 因为每个段都是电隔离的，并且由于每个段由其自己的信号线独立地服务，所以医师可以操作消融能量发生器来选择性地将消融能量传送到实际接触组织的区段。

公开(公告)号：WO1995010321A1

公开(公告)日：1995-04-20

申请号：PCT/US1994011750

申请日：1994-10-14

Applicant: EP TECHNOLOGIES, INC.

Inventor： EP TECHNOLOGIES, INC. ,  FLEISCHMAN, Sidney, D. ,  SWANSON, David, K. ,  McGEE, David, L. ,  BOURNE, Thomas ,  HOUSER, Russell, A.

IPC: A61N01/05

CPC classification number: A61B18/1492 ,  A61B5/6858 ,  A61B18/1402 ,  A61B18/1815 ,  A61B2017/003 ,  A61B2018/00083 ,  A61B2018/00107 ,  A61B2018/00148 ,  A61B2018/0016 ,  A61B2018/00196 ,  A61B2018/00214 ,  A61B2018/00267 ,  A61B2018/00755 ,  A61B2018/00875 ,  A61B2018/124 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1435 ,  A61B2018/1497 ,  A61B2018/1861 ,  A61N1/06 ,  A61N1/403

Abstract: A device for creating the lesions in body tissue includes a support element having an electromagnetic energy emitting region. When caused to emit electromagnetic energy, the region creates a single continuous lesion that is long and thin, having a lengththat is substantially greater than its width.

Abstract translation: 用于在身体组织中产生损伤的装置包括具有电磁能发射区域的支撑元件。 当引起发射电磁能量时，该区域产生长且薄的单个连续病变，其长度远大于其宽度。

公开(公告)号：WO1994021170A1

公开(公告)日：1994-09-29

申请号：PCT/US1994002811

申请日：1994-03-15

Applicant: EP TECHNOLOGIES, INC.

Inventor： EP TECHNOLOGIES, INC. ,  KORDIS, Thomas, F. ,  SWANSON, David, K. ,  PANESCU, Dorin

IPC: A61B05/04

CPC classification number: A61B5/6858 ,  A61B5/0422 ,  A61B18/1492 ,  A61B2018/00267 ,  A61B2018/1407 ,  A61B2018/1435 ,  A61B2562/0209 ,  A61B2562/043

Abstract: An electrode circuit (34) has a distal region (32) for carrying at least one electrode, a proximal region (30) for connection to an external apparatus, and an intermediate region electrically coupling the distal region with the proximal region. At least one, and preferably all, of the regions comprises a flexible ribbon cable having two or more adjacent tracks (T1-T6) of electrical conduction material and adjoining electrical insulating material. Use of ribbon cable makes possible reliable connections without the need for complicated multiplexing schemes at the distal region.

Abstract translation: 电极电路（34）具有用于承载至少一个电极的远端区域（32），用于连接到外部设备的近端区域（30）以及将远侧区域与近端区域电耦合的中间区域。 至少一个，优选地，所有这些区域包括具有导电材料和邻接电绝缘材料的两个或多个相邻轨道（T1-T6）的柔性带状电缆。 使用带状电缆使得可靠的连接成为可能，而不需要在远端区域进行复杂的复杂方案。

公开(公告)号：WO1994021168A1

公开(公告)日：1994-09-29

申请号：PCT/US1994002797

申请日：1994-03-15

Applicant: EP TECHNOLOGIES, INC.

Inventor： EP TECHNOLOGIES, INC. ,  KORDIS, Thomas, F. ,  SWANSON, David, K. ,  EDWARDS, Stuart, D.

IPC: A61B05/04

CPC classification number: A61N1/06 ,  A61B5/6857 ,  A61B5/6858 ,  A61B18/1492 ,  A61B18/1815 ,  A61B2018/0016 ,  A61B2018/00214 ,  A61B2018/00267 ,  A61B2018/00357 ,  A61B2018/00577 ,  A61B2018/00839 ,  A61B2018/0091 ,  A61B2018/1253 ,  A61B2018/1407 ,  A61B2018/1435 ,  A61B2218/002 ,  A61B2562/02 ,  A61B2562/043

Abstract: A probe (18) or cardiac diagnosis and/or treatment has a catheter tube (16). The distal end of the catheter tube carries first and second electrode elements (26, 88). The probe includes a mechanism (92) for steering the first electrode element relative to the second electrode element in multiple directions.

Abstract translation: 探针（18）或心脏诊断和/或治疗具有导管（16）。 导管管的远端承载第一和第二电极元件（26,88）。 探针包括用于在多个方向上相对于第二电极元件转向第一电极元件的机构（92）。

公开(公告)号：WO1998028039A3

公开(公告)日：1998-07-02

申请号：PCT/US1997023983

申请日：1997-12-19

Applicant: EP TECHNOLOGIES, INC.

Inventor： EP TECHNOLOGIES, INC. ,  PANESCU, Dorin ,  REINING, William ,  BURNSIDE, Robert ,  NGUYEN, Tuan ,  SWANSON, David, K. ,  ARNETT, David, W.

IPC: A61N01/37

公开(公告)号：WO1997025929A1

公开(公告)日：1997-07-24

申请号：PCT/US1997001174

申请日：1997-01-17

Applicant: EP TECHNOLOGIES, INC.

Inventor： EP TECHNOLOGIES, INC. ,  PANESCU, Dorin ,  SWANSON, David, K. ,  WHAYNE, James, G. ,  KORDIS, Thomas, F. ,  OWENS, Patrick, M. ,  JACKSON, Jerome ,  THOMPSON, Russel, B. ,  FLEISCHMAN, Sidney, D. ,  MCGEE, David

IPC: A61B17/39

CPC classification number: A61N1/06 ,  A61B18/1492 ,  A61B2017/00053 ,  A61B2017/00243 ,  A61B2017/22051 ,  A61B2017/22061 ,  A61B2018/00065 ,  A61B2018/00083 ,  A61B2018/00095 ,  A61B2018/00107 ,  A61B2018/00113 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00839 ,  A61B2018/1253 ,  A61B2018/1472 ,  A61B2218/002 ,  A61L29/085 ,  A61L29/145 ,  A61L31/10 ,  A61L31/145 ,  A61N1/056 ,  C08L1/02

Abstract: Electrode assemblies and associated systems employ a nonporous wall (22) having an exterior for contacting tissue. The exterior peripherally surrounds an interior area. The wall is essentially free of electrically conductive material. The wall is adapted to assume an expanded geometry having a first maximum diameter and a collapsed geometry having a second maximum diameter less than the first maximum diameter. The assemblies and systems include a lumen (34) that conveys a medium containing ions into the interior area. An element free of physical contact with the wall couples the medium within the interior area to a source of electrical energy to enable ionic transport of electrical energy from the source through the medium to the wall for capacitive coupling to tissue contacting the exterior of the wall.

Abstract translation: 电极组件和相关联的系统使用具有用于接触组织的外部的无孔壁（22）。 外部外围围绕着内部区域。 该壁基本上不含导电材料。 壁适于呈现具有第一最大直径和具有小于第一最大直径的第二最大直径的折叠几何形状的膨胀几何形状。 组件和系统包括将含有离子的介质输送到内部区域中的内腔（34）。 与壁物理接触的元件将内部区域内的介质耦合到电能源，以使电能从源通过介质到壁的电能离子传输，用于电容耦合到与壁的外部接触的组织。

公开(公告)号：WO1997025919A1

公开(公告)日：1997-07-24

申请号：PCT/US1997000913

申请日：1997-01-17

Applicant: EP TECHNOLOGIES, INC.

Inventor： EP TECHNOLOGIES, INC. ,  SWANSON, David, K. ,  PANESCU, Dorin ,  WHAYNE, James, G. ,  OWENS, Patrick, M. ,  FLEISCHMAN, Sidney, D. ,  THOMPSON, Russel, B. ,  JACKSON, Jerome

IPC: A61B05/04

CPC classification number: A61N1/06 ,  A61B18/1492 ,  A61B2017/00053 ,  A61B2017/00243 ,  A61B2017/22051 ,  A61B2017/22061 ,  A61B2018/00065 ,  A61B2018/00083 ,  A61B2018/00095 ,  A61B2018/00107 ,  A61B2018/00113 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00351 ,  A61B2018/00839 ,  A61B2018/1253 ,  A61B2018/1472 ,  A61B2218/002 ,  A61L29/085 ,  A61L29/145 ,  A61L31/10 ,  A61L31/145 ,  A61N1/056 ,  C08L1/02

Abstract: Systems and methods for heating or ablating tissue use a multifunctional electrode assembly (20). The electrode assembly includes a wall (22) comprising an electrically conductive material peripherally surrounding an interior area. The wall has an interior surface facing the interior area and an oppositely facing exterior surface. A first element operatively associated with the exterior surface of the wall is adapted to carry out a first predetermined electrical transmitting or sensing function affecting body tissue. A second element operatively associated with the interior surface of the wall is adapted to carry out, independent of the first element, a second predetermined electrical transmitting or sensing function affecting body tissue different than the first predetermined electrical function.

Abstract translation: 用于加热或消融组织的系统和方法使用多功能电极组件（20）。 电极组件包括壁（22），该壁（22）包括围绕内部区域的导电材料。 壁具有面向内部区域的内表面和相对的外表面。 可操作地与壁的外表面相关联的第一元件适于执行影响身体组织的第一预定的电传递或感测功能。 与壁的内表面可操作地相关联的第二元件适于独立于第一元件执行影响不同于第一预定电功能的身体组织的第二预定电传输或感测功能。

公开(公告)号：WO1997025916A1

公开(公告)日：1997-07-24

申请号：PCT/US1997000698

申请日：1997-01-17

Applicant: EP TECHNOLOGIES, INC.

Inventor： EP TECHNOLOGIES, INC. ,  WHAYNE, James, G. ,  JACKSON, Jerome ,  PANESCU, Dorin ,  KORDIS, Thomas, F. ,  THOMPSON, Russell, B. ,  OWENS, Patrick, M. ,  SWANSON, David, K. ,  MCGEE, David ,  FLEISCHMAN, Sidney, D.

IPC: A61B05/04

CPC classification number: A61N1/06 ,  A61B18/1492 ,  A61B2018/00065 ,  A61B2018/00083 ,  A61B2018/00095 ,  A61B2018/00113 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00839 ,  A61B2018/1253 ,  A61B2018/1472 ,  A61B2218/002 ,  A61L29/085 ,  A61L29/145 ,  A61L31/10 ,  A61L31/145 ,  C08L1/02

Abstract: Systems for ablating body tissue comprise a family of electrode assemblies. Each electrode assembly (22) includes an extruded wall carrying an amount of electrically conductive material co-extruded within it. The extruded walls possess different electrical resistivity values by virtue of different amounts of electrically conductive material co-extruded within the walls. The systems also include means for specifying, among the family, use of the electrode assemblies according to a function that correlates desired tissue ablation effects with electrical resistivity values of the walls.

Abstract translation: 用于消融身体组织的系统包括一组电极组件。 每个电极组件（22）包括承载一定量的导电材料的挤出壁，该导电材料在其内共挤出。 由于在壁内共挤出的不同量的导电材料，挤出的壁具有不同的电阻率值。 该系统还包括用于根据将期望的组织消融效应与壁的电阻率值相关联的功能来指定在家庭中使用电极组件的装置。

公开(公告)号：WO1996025094A1

公开(公告)日：1996-08-22

申请号：PCT/US1996002034

申请日：1996-02-16

Applicant: EP TECHNOLOGIES, INC.

Inventor： EP TECHNOLOGIES, INC. ,  SWANSON, David, K. ,  PANESCU, Dorin ,  WHAYNE, James, G.

IPC: A61B05/0402

CPC classification number: A61N1/403 ,  A61B1/0051 ,  A61B5/0422 ,  A61B5/04525 ,  A61B5/6855 ,  A61B5/6858 ,  A61B2562/0209 ,  A61B2562/043 ,  A61N1/056

Abstract: Systems and methods analyze bio-potential morphologies in body tissue. The systems and methods use a template of a bio-potential event of known cause in body tissue. The systems and methods compare this template to a sample of a bio-potential event externally triggered in body tissue. The systems and methods generate an output based upon this comparison. The systems and methods can be used to compare an event specific to the template of a cardiac event (T(i)) of known diagnosis to a sample of a placed cardiac event (P(i)). The comparison yields a matching coefficient (MCOEFF(i)) indicating how alike the input sample is to the input template. The matching coefficient can be used by the physician, for example, to aid in the location of sites that are potentially appropriate for ablation.

Abstract translation: 系统和方法分析身体组织中的生物潜能形态。 系统和方法使用身体组织中已知原因的生物潜在事件的模板。 系统和方法将此模板与身体组织中外部触发的生物潜在事件的样本进行比较。 系统和方法基于此比较生成输出。 系统和方法可以用于将已知诊断的心脏事件（T（i））的模板特有的事件与放置的心脏事件（P（i））的样本进行比较。 比较产生一个匹配系数（MCOEFF（i）），表示输入样本与输入模板的相似度。 例如，医生可以使用匹配系数来帮助可能适合于消融的部位的位置。