公开(公告)号：NZ306281A

公开(公告)日：1999-07-29

申请号：NZ30628196

申请日：1996-04-11

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BORET LI ,  RIEBE MICHAEL T

IPC: B65D83/38 ,  A61K9/00 ,  A61K9/12 ,  A61K9/72 ,  A61K31/137 ,  A61K31/57 ,  A61K31/573 ,  A61M15/00 ,  A61P11/00 ,  B05D5/08 ,  B65D83/14

Abstract: A metered dose inhaler having part or all of its internal surfaces coated with one or more fluorocarbon polymers, optionally in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising beclomethasone dipropionate or a physiologically acceptable solvate thereof, and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents or one or more excipients.

公开(公告)号：HU9800641A2

公开(公告)日：1998-08-28

申请号：HU9800641

申请日：1996-04-11

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI LI ,  RIEBE MICHAEL T

IPC: B65D83/38 ,  A61K9/00 ,  A61K9/12 ,  A61K9/72 ,  A61K31/137 ,  A61K31/57 ,  A61K31/573 ,  A61M15/00 ,  A61P11/00 ,  B05D5/08 ,  B65D83/14

Abstract: A metered dose inhaler having part or all of its internal surfaces coated with one or more fluorocarbon polymers, optionally in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising beclomethasone dipropionate or a physiologically acceptable solvate thereof, and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents or one or more excipients.

公开(公告)号：BG102022A

公开(公告)日：1998-07-31

申请号：BG10202297

申请日：1997-11-05

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL T

IPC: A61M15/00 ,  B05D5/08 ,  B65D83/00 ,  B65D83/14

Abstract: The inhaler is used for metering of inhalation medicamentouscompositions including salmetrol or its physiologically acceptablesalt and hydrogen fluoride propellant, optionally in combinationwith one or more other phyrmacologically active substances and oneor more fillers. It has partially or completely covered innersurfaces with one or more hydrogen fluoride polymers, optionallyin combination with one or more non hydrogen fluoride polymers.22 claims

公开(公告)号：BR9604979A

公开(公告)日：1998-06-09

申请号：BR9604979

申请日：1996-04-11

Applicant: GLAXO WELLCOME INC

Inventor： LI-BOVET LI ,  ASHURST IAN C ,  RIEBE MICHAEL T ,  HERMAN CRAIG S

IPC: B65D83/38 ,  A61K9/00 ,  A61K9/12 ,  A61K9/72 ,  A61K31/137 ,  A61K31/57 ,  A61K31/573 ,  A61M15/00 ,  A61P11/00 ,  B05D5/08 ,  B65D83/14

Abstract: A metered dose inhaler having part or all of its internal surfaces coated with one or more fluorocarbon polymers, optionally in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising beclomethasone dipropionate or a physiologically acceptable solvate thereof, and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents or one or more excipients.

公开(公告)号：SK139197A3

公开(公告)日：1998-04-08

申请号：SK139197

申请日：1996-04-11

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL T

IPC: B65D83/38 ,  A61K9/00 ,  A61K9/12 ,  A61K9/72 ,  A61K31/137 ,  A61K31/57 ,  A61K31/573 ,  A61M15/00 ,  A61P11/00 ,  B05D5/08 ,  B65D83/14

Abstract: A metered dose inhaler having part or all of its internal surfaces coated with one or more fluorocarbon polymers, optionally in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising beclomethasone dipropionate or a physiologically acceptable solvate thereof, and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents or one or more excipients.

公开(公告)号：CZ9703259A3

公开(公告)日：1998-03-18

申请号：CZ325997

申请日：1996-04-10

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL T

IPC: A61K9/00 ,  A61K9/12 ,  A61K9/72 ,  A61K31/135 ,  A61K31/137 ,  A61K31/57 ,  A61K31/573 ,  A61M15/00 ,  A61P11/08 ,  B05D5/08 ,  B05D7/22 ,  B05D7/24 ,  B65D83/14

CPC classification number: A61K9/008 ,  A61K9/124 ,  A61K31/137 ,  A61K31/57 ,  A61K31/573 ,  A61M15/009 ,  A61M2205/0222 ,  B65D83/54 ,  A61K31/135 ,  A61K2300/00

公开(公告)号：NO974737A

公开(公告)日：1997-12-11

申请号：NO974737

申请日：1997-10-13

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL T

IPC: A61K9/00 ,  A61K9/12 ,  A61K9/72 ,  A61K31/135 ,  A61K31/137 ,  A61K31/57 ,  A61K31/573 ,  A61M15/00 ,  A61P11/08 ,  B05D5/08 ,  B05D7/22 ,  B05D7/24 ,  B65D83/14

CPC classification number: A61K9/008 ,  A61K9/124 ,  A61K31/137 ,  A61K31/57 ,  A61K31/573 ,  A61M15/009 ,  A61M2205/0222 ,  B65D83/54 ,  A61K31/135 ,  A61K2300/00

公开(公告)号：NO974735L

公开(公告)日：1997-12-11

申请号：NO974735

申请日：1997-10-13

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL T

IPC: A61K9/12 ,  A61M15/00 ,  A61K31/56 ,  A61K31/569 ,  A61M15/08 ,  A61M16/00 ,  A61P11/00 ,  B05D5/00 ,  B05D5/08 ,  B65D83/14

Abstract: A metered dose inhaler having part or all of its internal surfaces coated with one or more fluorocarbon polymers, optionally in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising fluticasone propionate, or a physiologically acceptable solvate thereof, and a fluorocarbon propellant optionally in combination with one or more other pharmacologically active agents or one or more excipients.

公开(公告)号：NO974738D0

公开(公告)日：1997-10-13

申请号：NO974738

申请日：1997-10-13

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL T

IPC: B65D83/38 ,  A61K9/00 ,  A61K9/12 ,  A61K9/72 ,  A61K31/137 ,  A61K31/57 ,  A61K31/573 ,  A61M15/00 ,  A61P11/00 ,  B05D5/08 ,  B65D83/14 ,  A61M

Abstract: A metered dose inhaler having part or all of its internal surfaces coated with one or more fluorocarbon polymers, optionally in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising beclomethasone dipropionate or a physiologically acceptable solvate thereof, and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents or one or more excipients.

公开(公告)号：CY2402B1

公开(公告)日：2004-09-10

申请号：CY0400002

申请日：2004-01-02

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL T ,  BRITTO IGNATIUS LOY

IPC: A61K9/00 ,  A61K9/12 ,  A61K9/72 ,  A61K31/135 ,  A61K31/137 ,  A61K31/57 ,  A61K31/573 ,  A61M15/00 ,  A61P11/08 ,  B05D5/08 ,  B05D7/22 ,  B05D7/24 ,  B65D83/14

Abstract: Metered dose inhaler having all or part of its internal surfaces coated with one or more fluorocarbon polymers, opt. in combination with one or more non-fluorocarbon polymers, is used for dispensing an inhalation drug formulation comprising albuterol (also known as salbutamol) or one of its salts, and a fluorocarbon propellant, opt. in combination with one or more other pharmacologically active agents or one or more excipients. Also claimed is a metered dose inhaler system comprising a metered dose inhaler fitted into a suitable channelling device for oral or nasal inhalation of the drug formulation.