公开(公告)号：CY2401B1

公开(公告)日：2004-09-10

申请号：CY0400001

申请日：2004-01-02

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL T

IPC: A61K9/12 ,  A61K31/56 ,  A61K31/569 ,  A61M15/00 ,  A61M15/08 ,  A61M16/00 ,  A61P11/00 ,  B05D5/00 ,  B05D5/08 ,  B65D83/14

Abstract: A metered dose inhaler having part or all of its internal surfaces coated with one or more fluorocarbon polymers, optionally in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising fluticasone propionate, or a physiologically acceptable solvate thereof, and a fluorocarbon propellant optionally in combination with one or more other pharmacologically active agents or one or more excipients.

公开(公告)号：BG64117B1

公开(公告)日：2004-01-30

申请号：BG10202297

申请日：1997-11-05

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL T

IPC: A61M15/00 ,  B05D5/08 ,  B65D83/00 ,  B65D83/14

Abstract: The inhaler is used for metering of inhalation medicamentous compositions including salmetrol or its physiologically acceptable salt and hydrogen fluoride propellant, optionally in combination with one or more other pharmacologically active substances and one or more fillers. It has partially or completely covered inner surfaces with one or more hydrogen fluoride polymers, optionally in combination with one or more non hydrogen fluoride polymers. 21 claims

公开(公告)号：BG64039B1

公开(公告)日：2003-11-28

申请号：BG10197297

申请日：1997-10-15

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL T

IPC: A61K9/12 ,  A61K31/56 ,  A61K31/569 ,  A61M15/00 ,  A61M15/08 ,  A61M16/00 ,  A61P11/00 ,  B05D5/00 ,  B05D5/08 ,  B65D83/14

Abstract: The dosage fixing inhaler has partial or fully covered internal surfaces coated by one or more fluorocarbon polymers, optionally in combination with one or more nonfluorocarbon polymers. It is applied for the dispersion of medicamentous forms for inhalations consisting of fluticazon propionate or its physiologically acceptable solution and optionallyin fluorcarbon propellent combination with one or more pharmacologically active agents and one or more additional substances. 22 claims

公开(公告)号：NZ306278A

公开(公告)日：1999-07-29

申请号：NZ30627896

申请日：1996-04-10

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL T

IPC: A61K9/00 ,  A61K9/12 ,  A61K9/72 ,  A61K31/135 ,  A61K31/137 ,  A61K31/57 ,  A61K31/573 ,  A61M15/00 ,  A61P11/08 ,  B05D5/08 ,  B05D7/22 ,  B05D7/24 ,  B65D83/14 ,  B65D83/38 ,  A61K31/165

Abstract: Metered dose inhaler having all or part of its internal surfaces coated with one or more fluorocarbon polymers, opt. in combination with one or more non-fluorocarbon polymers, is used for dispensing an inhalation drug formulation comprising albuterol (also known as salbutamol) or one of its salts, and a fluorocarbon propellant, opt. in combination with one or more other pharmacologically active agents or one or more excipients. Also claimed is a metered dose inhaler system comprising a metered dose inhaler fitted into a suitable channelling device for oral or nasal inhalation of the drug formulation.

公开(公告)号：CZ9703261A3

公开(公告)日：1999-06-16

申请号：CZ326197

申请日：1996-04-11

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL T

IPC: B65D83/38 ,  A61K9/00 ,  A61K9/12 ,  A61K9/72 ,  A61K31/137 ,  A61K31/57 ,  A61K31/573 ,  A61M15/00 ,  A61P11/00 ,  B05D5/08 ,  B65D83/14

CPC classification number: A61K9/008 ,  A61K31/573 ,  A61M15/009 ,  A61M2205/0222 ,  B65D83/54 ,  B65D83/752

公开(公告)号：HU9802278A2

公开(公告)日：1999-01-28

申请号：HU9802278

申请日：1996-04-10

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI LI ,  RIEBE MICHAEL THOMAS

IPC: A61K9/12 ,  A61K31/56 ,  A61K31/569 ,  A61M15/00 ,  A61M15/08 ,  A61M16/00 ,  A61P11/00 ,  B05D5/00 ,  B05D5/08 ,  B65D83/14

Abstract: A metered dose inhaler having part or all of its internal surfaces coated with one or more fluorocarbon polymers, optionally in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising fluticasone propionate, or a physiologically acceptable solvate thereof, and a fluorocarbon propellant optionally in combination with one or more other pharmacologically active agents or one or more excipients.

公开(公告)号：HU9801526A2

公开(公告)日：1998-10-28

申请号：HU9801526

申请日：1996-04-10

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI LI ,  RIEBE MICHAEL T

IPC: A61K9/00 ,  A61K9/12 ,  A61K9/72 ,  A61K31/135 ,  A61K31/137 ,  A61K31/57 ,  A61K31/573 ,  A61M15/00 ,  A61P11/08 ,  B05D5/08 ,  B05D7/22 ,  B05D7/24 ,  B65D83/14

Abstract: Metered dose inhaler having all or part of its internal surfaces coated with one or more fluorocarbon polymers, opt. in combination with one or more non-fluorocarbon polymers, is used for dispensing an inhalation drug formulation comprising albuterol (also known as salbutamol) or one of its salts, and a fluorocarbon propellant, opt. in combination with one or more other pharmacologically active agents or one or more excipients. Also claimed is a metered dose inhaler system comprising a metered dose inhaler fitted into a suitable channelling device for oral or nasal inhalation of the drug formulation.

公开(公告)号：BR9604977A

公开(公告)日：1998-06-09

申请号：BR9604977

申请日：1996-04-10

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  RIEBE MICHAEL T ,  LI-BOVET LI

IPC: A61M15/00 ,  B05D5/08 ,  B65D83/00 ,  B65D83/14

Abstract: A metered dose inhaler characterised in that part or all of its internal surfaces are coated with a polymer blend of one or more fluorocarbon polymers in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising salmeterol, or a physiologically acceptable salt thereof, and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents or one or more excipients, wherein a) the fluorocarbon polymer is selected from the group consisting of PTFE, PFA, FEP and mixtures thereof, b) the non-fluorocarbon polymer is selected from the group consisting of polyamideimides, polyimides, polyethersulfones, polyphenylene sulfides and amine-formaldehyde thermosetting resins, (c) the inhaler comprises a can made of metal whose interior surfaces are coated with the polymer blend.

公开(公告)号：TR9701169T1

公开(公告)日：1998-03-21

申请号：TR9701169

申请日：1996-04-10

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL THOMAS

IPC: A61M15/00 ,  B05D5/08 ,  B65D83/00 ,  B65D83/14

CPC classification number: B65D83/54 ,  A61M15/009 ,  A61M2205/0222 ,  A61M2205/0233

公开(公告)号：CZ9703258A3

公开(公告)日：1998-03-18

申请号：CZ325897

申请日：1996-04-10

Applicant: GLAXO WELLCOME INC

Inventor： ASHURST IAN C ,  HERMAN CRAIG S ,  LI-BOVET LI ,  RIEBE MICHAEL T

IPC: A61K9/12 ,  A61K31/56 ,  A61K31/569 ,  A61M15/00 ,  A61M15/08 ,  A61M16/00 ,  A61P11/00 ,  B05D5/00 ,  B05D5/08 ,  B65D83/14

CPC classification number: B65D83/54 ,  A61M15/009 ,  A61M2205/0222