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公开(公告)号：JPS6347639A
公开(公告)日：1988-02-29
申请号：JP19034886
申请日：1986-08-13
Applicant: HAMAMATSU PHOTONICS KK
Inventor： ITO TOSHIAKI , FUJIWAKE HIDEJI , YAMASHITA YUTAKA , OOTA KAZUYOSHI
IPC: G01N21/80
Abstract: PURPOSE:To measure the concn. of a hydrogen ion photoelectrically at a high speed, by selecting light having a specific wavelength by a spectroscope to allow the same to transmit through or reflect from a polymer membrane through an optical fiber and measuring the transmitted or reflected light by a photometric apparatus. CONSTITUTION:In a polymer membrane 2, the intensity of transmitted light having a specific wavelength is most sensitive to pH change and the intensity of transmitted light having a separate specific wavelength is most insensitive thereto. Therefore, two lights having specific wavelengths are successively selected by a spectroscope 7 to be incident on the incident end 5a of an optical fiber 5. The light transmitted through the polymer membrane 2 receiving the effect of a solution 1 to be measured and reflected from a polymer membrane support 3 is incident on a light detector 8 from the end 5b of the optical fiber 5. The detector 8 calculates outputs at two wavelengths and the ratio of both outputs is operated by an operation device 9 to detect pH of the solution 1. By this method, the concn. of the hydrogen ion of the solution to be measured an be measured photoelectrically at a high speed.
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公开(公告)号：JPS62124443A
公开(公告)日：1987-06-05
申请号：JP26555285
申请日：1985-11-26
Applicant: HAMAMATSU PHOTONICS KK
Inventor： HIRUMA TERUO , HAYAKAWA TAKESHI , YAMASHITA YUTAKA , OOTA KAZUYOSHI , MORI SHINSUKE
Abstract: PURPOSE:To obtain information on the inside of a body by irradiating the inside of the body with light pulses from outside and detecting light which is affected by the body inside. CONSTITUTION:If there is a lump which hardly transmits light in the center of the body, light pulses which are passed through a fiber 3 for input and projected are cut off, straight traveling light does not reach the shadow of the lump, and light diffracted and refracted by the edge of the lump reaches a light receiving part 2. When there is not the lump, the light pulses are propagated uniformly to be made incident on the light receiving part 2. They are compared by a control and arithmetic unit 4 to estimate the size and position of foreign matter accurately.
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公开(公告)号：JPS6228645A
公开(公告)日：1987-02-06
申请号：JP16819885
申请日：1985-07-30
Applicant: HAMAMATSU PHOTONICS KK
Inventor： NAKAMURA TATSU , SUZUKI SHIYOUHACHI , HAYAKAWA TAKESHI , FUJIWAKE HIDEJI , YAMASHITA YUTAKA , OOTA KAZUYOSHI
Abstract: PURPOSE:To measure the thickness and transmittivity of vital tissue and to diagnose the tissue by providing an adjustable supporting device for supporting device for supporting a projecting part and photodetecting part in such a mannr that the space therebetween can be adjusted in the state of aligning the optical axes thereof and measuring the light transmitted at a specified distance in the vital tissue. CONSTITUTION:An optical fiber 1 for projection passes through the inside of a hollow projecting cylinder 4 and light is emitted from the top end thereof and is refleced by a mirror 2 for projection provided in the cylinder 4. The reflected light is rereleased through a projecting window 3 to the outside. The light is transmitted through the vital tissue 100 and is made incident on a photodetecting window 6 provided to a photodetection side cylinder 9. After the light is reflected by a photodetection side mirror 7, the light is made incident on a photodetection side fiber 8 in the cylinder 9. A guide rod 5 is provided to the body part of the cylinder 4 perpendicularly thereto and the cylinder 9 is guided by the rod 5 to move in a vertical direction in parallel with the cylinder 4. A screw 10 is provided to a sliding coupling block 9a provided to the cyliner 9 to maintain the specified thickness of the tissue 100.
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公开(公告)号：JP2014228430A
公开(公告)日：2014-12-08
申请号：JP2013108905
申请日：2013-05-23
Applicant: 国立大学法人浜松医科大学 , Hamamatsu Univ School Of Medicine , 浜松ホトニクス株式会社 , Hamamatsu Photonics Kk
Inventor： SETO MITSUTOSHI , SASABE JUN , TAKAHASHI HIRONORI , YAMASHITA YUTAKA , HAYASHI MASAHIRO
Abstract: 【課題】試料のイオン化効率を向上できると共にメモリー効果を低減できる試料分析装置を提供する。【解決手段】試料分析装置1では、プローブ2が中空光ファイバ11,12によって構成され、ポストイオン化用レーザ5からの出射光5aが中空光ファイバ11,12に導光されるようになっている。これにより、中空光ファイバ11,12内を吸引されていく試料Sの蒸気とポストイオン化用レーザ5の出射光5aとの相互作用領域及び相互作用時間を十分に確保できるので、試料Sのイオン化効率を向上できる。また、比較的高い光強度を有するポストイオン化用レーザ5からの出射光5aが中空光ファイバ11,12に導光するので、中空光ファイバ11,12に吸着した分子の脱離が促進され、メモリー効果の低減が図られる。【選択図】図1
Abstract translation: 要解决的问题：提供一种能够提高样品的离子化效率并且还降低记忆效应的样本分析装置。解决方案：样本分析器1被构造成使得探针2由中空光纤11和12构成，并且发射光 来自后电离激光器5的电荷5a被引导到中空光纤11和12.因此，由于吸入中空光纤11和12的样品S的蒸气与从中心光纤11吸收的发射光5a之间的相互作用面积和相互作用时间 可以充分确保电离后激光器5，可以获得样品S的电离效率的提高。 然后，由于来自后电离激光器5的光强度相对较高的发光5a被引导到中空光纤11和12，所以促进吸附在中空光纤11和12上的分子的解吸，从而获得 减少记忆效应。
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公开(公告)号：JP2011232301A
公开(公告)日：2011-11-17
申请号：JP2010105526
申请日：2010-04-30
Applicant: Hamamatsu Photonics Kk , Hamamatsu Univ School Of Medicine , 国立大学法人浜松医科大学 , 浜松ホトニクス株式会社
Inventor： YAMAKI ETSUKO , YAMASHITA YUTAKA , ODA MOTOKI , SUZUKI HIROAKI , SUZUKI TOSHIHIKO , WATANABE YUJI , KOGA SHUNSAKU
IPC: G01N21/17 , A61B5/1455 , G01N21/35 , G01N21/3577 , G01N21/359
CPC classification number: G01N21/17 , A61B5/14546 , A61B5/1455 , A61B2562/0242 , G01N21/359 , G01N21/49
Abstract: PROBLEM TO BE SOLVED: To provide a method of and an apparatus for measuring scattering absorber, in which a measurement result without the effect of mediation composition can be obtained in a simple manner.SOLUTION: A light P with a predetermined wavelength is entered from one light incident position I set on a surface Ba of a scattering absorber B. The light P having propagated inside the scattering absorber B is detected at one light detection position D set on the surface Ba of the scattering absorber B, thereby obtaining a light detection signal. Based on the light detection signal, a time waveform is acquired for a light intensity of the detected light, and based on the time waveform, an average optical path length L of the light P inside the scattering absorber B and information regarding the amount of a substance to be measured in a measuring area B1 are calculated. In the calculation, the information regarding the amount of measured substance is corrected based on the average optical path length L, so that the amount of measured substance becomes larger as the optical wave length L becomes longer.
Abstract translation: 要解决的问题：提供一种测量散射吸收体的方法和装置，其中可以简单地获得不具有调解组合物的作用的测量结果。 解决方案：从设置在散射吸收体B的表面Ba上的一个光入射位置I进入具有预定波长的光P.在散射吸收体B内传播的光P在一个光检测位置D设定 在散射吸收体B的表面Ba上，由此获得光检测信号。 基于光检测信号，针对检测光的光强度获取时间波形，并且基于时间波形，散射吸收体B内的光P的平均光路长度L和关于 计算在测量区域B1中要测量的物质。 在计算中，基于平均光程长度L校正测量物质量的信息，使得随着光波长L变长，被测物质的量变大。 版权所有（C）2012，JPO＆INPIT
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Patent Agency Ranking
公开(公告)号：JP2009148313A
公开(公告)日：2009-07-09
申请号：JP2007326378
申请日：2007-12-18
Applicant: Hamamatsu Photonics Kk , 浜松ホトニクス株式会社
Inventor： YOSHIMOTO KENJI , MIWA MITSUHARU , SUZUKI TOSHIHIKO , YAMASHITA DAISUKE , YAMASHITA YUTAKA
Abstract: PROBLEM TO BE SOLVED: To provide a biological measuring apparatus and a calibration tool reducing the quantity of the work for the measurement for calibration.
SOLUTION: The biological measuring apparatus comprises a plurality of optical fibers 11 (light emission ends) for emitting light to a measured region; a plurality of optical fibers 11 (light detection ends) for receiving diffused light from the measured region; a vessel 3 having a measurement space 3a for storing the measured region to support the light emission end and the light detection end toward the measurement space 3a; an internal information calculation part for calculating internal information based on the diffusion light coming into the light emission end; the detachable calibration tool 12 having a light diffusing target 13 facing the measurement space 3a, configured to cover an opening 3b of the vessel 3; and a calibration data calculation part for calculating calibration data for the plurality of light detection ends respectively based on the diffusion light coming to the light detection ends from the light diffusing target by the light irradiation from the light emission end. The internal information calculation part calculates the internal information based further on the calibration data.
COPYRIGHT: (C)2009,JPO&INPITAbstract translation: 要解决的问题：提供生物测量装置和校准工具，减少用于校准的测量的工作量。 解决方案：生物测量装置包括用于将光发射到测量区域的多个光纤11（发光端）; 用于从测量区域接收漫射光的多个光纤11（光检测端）; 具有测量空间3a的容器3，用于将测量区域存储以支持发光端，光检测端朝向测量空间3a; 内部信息计算部分，用于基于进入发光端的漫射光来计算内部信息; 具有面向测量空间3a的光扩散目标13的可拆卸校准工具12构造成覆盖容器3的开口3b; 以及校准数据计算部分，用于基于从光发射端的光照射到来自光漫射目标的光检测端的扩散光，分别计算多个光检测端的校准数据。 内部信息计算部分基于校准数据进一步计算内部信息。 版权所有（C）2009，JPO＆INPIT
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公开(公告)号：JP2008101992A
公开(公告)日：2008-05-01
申请号：JP2006283955
申请日：2006-10-18
Applicant: Hamamatsu Photonics Kk , 浜松ホトニクス株式会社
Inventor： YAMASHITA DAISUKE , SUZUKI TOSHIHIKO , YAMASHITA YUTAKA
Abstract: PROBLEM TO BE SOLVED: To provide mammography equipment enabling increasing of the ratios of the number of light irradiation positions and the number of light detection positions, over the number of optical fibers.
SOLUTION: A mammography equipment 1 is used to irradiate a breast of a tested person with light and detect diffused light to acquire the internal information of the breast. The mammography equipment 1 includes a container 3 surrounding a sagging breast, a plurality of optical fibers 11 fixed to the container 3 and extending toward the inside of the container 3 for irradiation and detection of the light, and a rotation mechanism 21 for rotating the container 3 around a predetermined axis C in the sagging direction of the breast.
COPYRIGHT: (C)2008,JPO&INPITAbstract translation: 要解决的问题：提供能够增加光照射位置的数量和光检测位置的数量的相对于光纤数量的乳房X射线摄影设备。
解决方案：使用乳房X线照相设备1，用光照射受检者的乳房，并检测扩散的光以获取乳房的内部信息。 乳房摄影设备1包括围绕下垂乳房的容器3，固定到容器3并朝向容器3内部延伸以照射和检测光的多个光纤11，以及用于使容器旋转的旋转机构21 3围绕乳房下垂方向的预定轴线C。 版权所有（C）2008，JPO＆INPIT
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公开(公告)号：JP2002139420A
公开(公告)日：2002-05-17
申请号：JP2000331247
申请日：2000-10-30
Applicant: HAMAMATSU PHOTONICS KK
Inventor： YAMASHITA YUTAKA , MIWA MITSUHARU , URAGAMI TSUNEYUKI
Abstract: PROBLEM TO BE SOLVED: To provide a calibration method of a scattered absorber measuring apparatus which enables easier execution of measurement for calibration and the calculation of an instrument function and the scattered absorber measuring apparatus using the same. SOLUTION: As scattered absorber SM to be measured by the scattered absorber measuring apparatus, a scattered absorber for calibration with a known optical parameter is set and pulse light from a light source 20 is made incident from a light incidence position A through a light guide 40a for light incidence and the pulse light propagated scattering through the scattered absorber SM is detected by a photo detector 30 through a light guide 40b for detecting light from a light detection position B to perform a measurement for calibration. A measuring waveform obtained by a signal processing part 50 undergoes a comparison operation with a theoretical waveform by an instrument function calculating part 61 of an arithmetic processing part 60 to calculate the instrument function with a measuring apparatus itself. This facilitates the measurement for calibration and the calculation of the instrument function.
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公开(公告)号：JPH1137851A
公开(公告)日：1999-02-12
申请号：JP19590797
申请日：1997-07-22
Applicant: HAMAMATSU PHOTONICS KK
Inventor： URAGAMI TSUNEYUKI , ANDO TARO , YAMASHITA YUTAKA
Abstract: PROBLEM TO BE SOLVED: To provide a light waveform measuring apparatus of a simple structure and a high counting rate capable of high-precision measurement. SOLUTION: Photons of a light to be measured having a specified cycle period T outputted from a light source 1 to be measured strike a photo detector 2 composed of an HPD(hybrid photo detector), etc., and is converted into an electric pulse. This electric pulse is sent to a multi-valuing circuit 4 via a preamplifier 3. The multi-valuing circuit 4 compares this signal with a threshold value or a plurality of threshold values, and outputs specified pulse signals from output terminals provided correspondingly while it exceeds respective threshold values. An arithmetic unit 5 synchronized with a cycle period T by a synchronous circuit 8 decides the number of photons on the basis of this pulse signal, and stores it in a corresponding time region of a storage unit 6 having time regions obtained by dividing the period T into n channels. A waveform outputting apparatus 7 reads information stored in the memory unit 6, and reconstitutes the waveform of light to be measured.
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40.发明专利
公开(公告)号：JPH04191642A
公开(公告)日：1992-07-09
申请号：JP32210590
申请日：1990-11-26
Applicant: HAMAMATSU PHOTONICS KK
Inventor： ODA MOTOKI , YAMASHITA YUTAKA , OTA KAZUYOSHI , TAMURA MAMORU , NISHIMURA GORO
IPC: G01N21/49 , A61B5/145 , A61B5/1455
Abstract: PURPOSE:To detect an absolute value of the concentration of hemoglobin in blood, for instance, in addition to the state of a change in an organism by applying a pulse light to a scattering medium containing a light-absorbing substance. CONSTITUTION:Five kinds of pulse lights selected from a wavelength band of 670nm to 1.33mum are applied to a scattering medium containing oxidation-type hemoglobin, reduction-type hemoglobin, cytochrome and myoglobin, for instance, and the intensity of light for each wavelength is measured. Utilizing that a scattering profile in the case when no light-absorbing substance exists in the scattering medium does not change according to the wavelength, the scattering profile is removed from simultaneous equations of a time-base profile of the intensity of light for each wavelength obtained herein and the scattering profile, and thereby concentration V is obtained. The concentration V is calculated by the equation on the right. In the equation, K denotes a constant of absorption of lights of wavelengths lambda1 and lambda2, C denotes the velocity of light in the scattering medium, f1 denotes the light intensity of the light of the wavelength lambda1 at times t1 and t2, and f2 denotes the light intensity of the light of the wavelength lambda2 at the times t1 and t2.
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