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公开(公告)号：AU4053600A
公开(公告)日：2000-10-16
申请号：AU4053600
申请日：2000-03-30
Applicant: IDEXX LAB INC
Inventor： LAWTON ROBERT , MERMER BRION , FRANCOEUR GREG , KRAH REGIS
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公开(公告)号：CA2329152A1
公开(公告)日：2000-10-05
申请号：CA2329152
申请日：2000-03-30
Applicant: IDEXX LAB INC
Inventor： LAWTON ROBERT , KRAH REGIS , FRANCOEUR GREG , MERMER BRION
IPC: C12P21/08 , A61K38/00 , A61K39/00 , A61P37/08 , C07K7/06 , C07K7/08 , C07K16/06 , C07K16/28 , C07K16/44 , C12N7/00 , A61K39/395
Abstract: Disclosed is an isolated and purified peptide comprising a leucine positione d two peptide bonds away from a tyrosine-arginine pair, such as having the configuration: leucine-blank-blank-tyrosine-arginine, tyrosine-arginine-blan k- blank-leucine, or, leucine-blank-blank-tyrosine-arginine-blank-blank-leucine , where blank is any amino acid. Other peptides of the invention include those with the sequence cysteine-blank-blank-proline-histidine-blank-blank-blank- cysteine; cysteine-blank-proline-histidine-blank-proline-blank-blank-cystein e. The peptides can be linked to a carrier such as a multiply antigen protein o r a plant virus particle. Isolated and purified peptides of the invention can be used to induce canine autoantibodies directed to the canine igE molecule.
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公开(公告)号：CA2329148A1
公开(公告)日：2000-10-05
申请号：CA2329148
申请日：2000-03-30
Applicant: IDEXX LAB INC
Inventor： MERMER BRION , FRANCOEUR GREG , LAWTON ROBERT
Abstract: Disclosed are binding proteins that specifically bind to an isolated and purified peptide comprising a leucine positioned two peptide bonds away from a tyrosine-arginine pair. Other binding proteins of the invention include those that specifically bind to an isolated and purified peptide with the sequence cysteine-blank-blank-proline-histidine-blank-blank-blank-cysteine (SEQ ID NO:6) or cysteine-blank-proline-histidine-blank-proline-blank-blank-cysteine (SEQ ID NO:9).
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