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公开(公告)号:NZ563477A
公开(公告)日:2010-02-26
申请号:NZ56347703
申请日:2003-11-28
Applicant: KERATEC LTD
Inventor: KELLY ROBERT JAMES , RODDICK-LANZILOTTA ALISA DAWN
IPC: A61K8/65 , A61Q1/02 , A61Q1/06 , A61Q1/10 , A61Q3/02 , A61Q5/02 , A61Q5/04 , A61Q5/06 , A61Q5/12 , A61Q9/02 , A61Q19/00 , A61Q19/08 , A61Q19/10
Abstract: Disclosed is a personal care formulation including a S-sulfonated keratin protein fraction. The keratin protein fraction may be intact or hydrolysed. Preferably the keratin protein fraction is from the high sulfur protein family wherein the cysteine content of the keratin protein may be about 4%. (62) Divided Out of 540294
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公开(公告)号:AU2003238745B2
公开(公告)日:2008-12-11
申请号:AU2003238745
申请日:2003-06-10
Applicant: KERATEC LTD
Inventor: RODDICK-LANZILOTTA ALISA DAWN , DIAS SUBASINGHE NISANKE GEORGE , PEPLOW PHILIP VICTOR , KELLY ROBERT JAMES
Abstract: The invention provides a biocompatible material derived from keratin that is useful for many aspects of medical treatment of bone. The keratin material is preferably S-sulfonated and enriched in intermediate filament proteins of high molecular weight. The keratin material may be porous for use as a bone replacement and augmentation product but also provided is the use of dense keratin materials in bone treatment for use as an internal fixation appliance in the treatment of bone fractures and bone regeneration, and a method for preparing the keratin material for use in the preservation, restoration and development of form and function of bone.
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公开(公告)号:AU2007332757A1
公开(公告)日:2008-06-19
申请号:AU2007332757
申请日:2007-12-11
Applicant: KERATEC LTD , WEBER JEFFREY A
Inventor: ALI MOHAMMAD AZAM , MARSH CLIVE , KELLY ROBERT JAMES
Abstract: The invention relates to a porous keratin construct material comprising keratin protein for use in wound healing applications. The porous keratin construct is capable of bio-absorbing into a wound to promote wound healing. The rate at which the construct bio-absorbs into the wound may be controlled altered by controlling the degree of disulfide cross-linking between the keratin proteins in the porous keratin construct. The invention is also related to a method of making the porous keratin construct.
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公开(公告)号:ES2292795T3
公开(公告)日:2008-03-16
申请号:ES02758965
申请日:2002-07-17
Applicant: KERATEC LTD
Inventor: KELLY ROBERT JAMES , WORTH GILLIAN HELEN , RODDICK-LANZILOTTA AILSA DAWN , RANKIN DOUGLAS ALEXANDER , ELLIS GREGORY DAVID , MESMAN PAUL JOHANNES ROY
Abstract: Un procedimiento para la preparación de derivados de la queratina de alto peso molecular que son de tamaño similar, o de mayor tamaño, que la proteína queratina originalmente expresada en la fuente de queratina, incluyendo el procedimiento una primera etapa de fase de digestión de sulfonación de una fuente de queratina mediante sulfitólisis oxidativa seguida de una segunda etapa de extracción acuosa repetitiva mediante un lavado gradual controlado que implica la separación de la queratina soluble de la insoluble y la posterior retroextracción de la queratina insoluble, por lo que se produce un derivado de la queratina S-sulfonada de alto peso molecular.
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公开(公告)号:DE60222553D1
公开(公告)日:2007-10-31
申请号:DE60222553
申请日:2002-07-17
Applicant: KERATEC LTD
Inventor: KELLY ROBERT JAMES , WORTH GILLIAN HELEN , RODDICK-LANZILOTTA AILSA DAWN , RANKIN DOUGLAS ALEXANDER , ELLIS GREGORY DAVID , MESMAN PAUL JOHANNES , SUMMERS CONAL GARTH , SINGLETON DIANE JOYCE
Abstract: A process for the preparation of soluble proteins of high molecular weight with little or no damage to the structural integrity of the proteins. The process is economically and environmentally acceptable by virtue of the cost of reagents that are used, and the recycling of some of those reagents, and is suitable for the production of soluble proteins on a large scale. The process includes a first stage using oxidative sulfitolysis followed by a second stage using mild conditions to extract the soluble protein. In the case of wool as the protein source the process leads to the production of soluble keratin proteins fractionated into the classes S-sulfonated keratin intermediate filament proteins and S-sulfonated keratin high sulfur proteins.
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公开(公告)号:AU2002330798B2
公开(公告)日:2007-06-21
申请号:AU2002330798
申请日:2002-08-30
Applicant: KERATEC LTD
Inventor: RODDICK-LANZILOTTA ALISA DAWN , BRYSON WARREN GLEN , RANKIN DOUGLAS ALEXANDER , KELLY ROBERT JAMES
Abstract: Film, fibre, foam and adhesive materials are produced from soluble S-sulfonated keratins. Once formed, the films, fibres, foams or adhesives are treated to modify the properties of the materials, in particular to improve the wet strength of the materials. Treatments used include removal of the S-sulfonate group by treatment with a reducing agent, treatment with an acid or treatment with a common protein crosslinking agent or treatment with a reduced form of keratin or keratin protein. The films are made by solvent casting a solution of S-sulfonated keratin proteins, the foam made by freeze-drying a solution of S-sulfonated keratin proteins and the fibres made by extruding a solution of a S-sulfonated keratin protein.
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公开(公告)号:BR0316793A
公开(公告)日:2005-11-01
申请号:BR0316793
申请日:2003-11-28
Applicant: KERATEC LTD
Inventor: KELLY ROBERT JAMES , RODDICK-LANZILOTTA ALISA DAWN
IPC: A61K8/65 , A61Q1/02 , A61Q1/06 , A61Q1/10 , A61Q3/02 , A61Q5/02 , A61Q5/04 , A61Q5/06 , A61Q5/12 , A61Q9/02 , A61Q19/00 , A61Q19/08 , A61Q19/10 , A61K7/00
Abstract: A range of personal care products that include a keratin protein fraction. The fraction may be intact or hydrolysed. It is preferably S-sulfonated. The content of the fraction may range from 0.001% to 50%. In most formulations its content will be less than 1% although in certain products such as nail care products the content will be higher. A wide range of personal care products are described including shampoos, body gels and lotions, conditioners, creams and cosmetics generally.
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公开(公告)号:BR0311723A
公开(公告)日:2005-03-01
申请号:BR0311723
申请日:2003-06-10
Applicant: KERATEC LTD , UNIV OTAGO , SUBASINGHE NISANKE GEORGE PREM
Abstract: The invention provides a biocompatible material derived from keratin that is useful for many aspects of medical treatment of bone. The keratin material is preferably S-sulfonated and enriched in intermediate filament proteins of high molecular weight. The keratin material may be porous for use as a bone replacement and augmentation product but also provided is the use of dense keratin materials in bone treatment for use as an internal fixation appliance in the treatment of bone fractures and bone regeneration, and a method for preparing the keratin material for use in the preservation, restoration and development of form and function of bone.
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公开(公告)号:BR0212389A
公开(公告)日:2004-08-17
申请号:BR0212389
申请日:2002-08-30
Applicant: KERATEC LTD
Inventor: KELLY ROBERT JAMES , RANKIN DOUGLAS ALEXANDER , RODDICK-LANZILOTTA ALISA DAWN , BRYSON WARREN GLEN
IPC: B29C41/12 , C08H1/06 , C08J5/18 , C08J9/28 , C09J189/00 , D01F4/00 , C08J9/26 , C08J3/24 , C09J189/04 , D01C3/00 , D01F8/02
Abstract: Film, fibre, foam and adhesive materials are produced from soluble S-sulfonated keratins. Once formed, the films, fibres, foams or adhesives are treated to modify the properties of the materials, in particular to improve the wet strength of the materials. Treatments used include removal of the S-sulfonate group by treatment with a reducing agent, treatment with an acid or treatment with a common protein crosslinking agent or treatment with a reduced form of keratin or keratin protein. The films are made by solvent casting a solution of S-sulfonated keratin proteins, the foam made by freeze-drying a solution of S-sulfonated keratin proteins and the fibres made by extruding a solution of a S-sulfonated keratin protein.
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公开(公告)号:CA2451408A1
公开(公告)日:2003-02-13
申请号:CA2451408
申请日:2002-07-17
Applicant: KERATEC LTD
Inventor: RANKIN DOUGLAS ALEXANDER , RODDICK-LANZILOTTA AILSA DAWN , KELLY ROBERT JAMES , WORTH GILLIAN HELEN , ELLIS GREGORY DAVID , MESMAN PAUL JOHANNES ROY , SINGLETON DIANE JOYCE , SUMMERS CONAL GARTH
IPC: B01D11/02 , C07K1/02 , C07K1/12 , C07K1/14 , C07K1/30 , C07K1/34 , C07K14/435 , C07K14/47 , C07K1/107 , C07K2/00
Abstract: A process for the preparation of soluble proteins of high molecular weight with little or no damage to the structural integrity of the proteins. The process is economically and environmentally acceptable by virtue of the cost of reagents that are used, and the recycling of some of those reagents, and is suitable for the production of soluble proteins on a large scale. The proces s includes a first stage using oxidative sulfitolysis followed by a second sta ge using mild conditions to extract the soluble protein. In the case of wool as the protein source the process leads to the production of soluble keratin proteins fractionated into the classes S-sulfonated keratin intermediate filament proteins and S-sulfontated keratin high sulfur proteins.
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