Abstract:
PROBLEM TO BE SOLVED: To provide a protein thin film and a protein fiber manufactured from S-sulfonated keratin derivatives, and to provide a method of manufacturing the protein thin film and the protein fiber. SOLUTION: The method of manufacturing the protein thin film by performing solvent casting of an solution of S-sulfonated keratin protein, and the method of manufacturing the protein fiber by extruding a solution of S-sulfonated keratin into an aqueous solution containing a reductant and salts that causes the protein in the solution to become insoluble are provided. Further, the protein thin film and protein fiber manufactured by the method of manufacturing the protein thin film and protein fiber are also provided. COPYRIGHT: (C)2009,JPO&INPIT
Abstract:
Soluble keratin derivatives are disclosed. The soluble keratin derivatives may include a soluble keratin protein having at least one substituted chemical group at a lysine group, terminal amine group and/or hydroxyl amino acid group of a soluble keratin protein. Soluble keratin derivatives may be formed by succinylation or quaternisation, or by reaction with fatty acid derivatives. The soluble keratin derivatives may be used in personal care formulations, and may also comprise mixtures of several different soluble keratin derivatives.
Abstract:
Film, fibre, foam and adhesive materials are produced from soluble S-sulfonated keratins. Once formed, the films, fibres, foams or adhesives are treated to modify the properties of the materials, in particular to improve the wet strength of the materials. Treatments used include removal of the S-sulfonate group by treatment with a reducing agent, treatment with an acid or treatment with a common protein crosslinking agent or treatment with a reduced form of keratin or keratin protein. The films are made by solvent casting a solution of S-sulfonated keratin proteins, the foam made by freeze-drying a solution of S-sulfonated keratin proteins and the fibres made by extruding a solution of a S-sulfonated keratin protein.
Abstract:
The invention provides a biocompatible materal derived from keratin that is useful for many aspects of medical treatment of bone. The keratin materal is preferably S-sulfonated and enriched in intermediate filament proteins of hi gh molecular weight. The keratin material may be porous for use as a bone replacment and augmentation product but also provided is the use of dense keratin materials in bone treatment for use as an internal fixation applianc e in the treatment of bone fractures and bone regeneration, and a method for preparing the keratin material for use in the preservation, restoration and development of form and function of bone.
Abstract:
A process for the preparation of soluble proteins of high molecular weight with little or no damage to the structural integrity of the proteins. The process is economically and environmentally acceptable by virtue of the cost of reagents that are used, and the recycling of some of those reagents, and is suitable for the production of soluble proteins on a large scale. The proces s includes a first stage using oxidative sulfitolysis followed by a second sta ge using mild conditions to extract the soluble protein. In the case of wool as the protein source the process leads to the production of soluble keratin proteins fractionated into the classes S-sulfonated keratin intermediate filament proteins and S-sulfontated keratin high sulfur proteins.