公开(公告)号：WO2008073376A3

公开(公告)日：2008-10-09

申请号：PCT/US2007025240

申请日：2007-12-11

Applicant: KERATEC LTD ,  WEBER JEFFREY A ,  KELLY ROBERT JAMES ,  MARSH CLIVE ,  ALI MOHAMMAD AZAM ,  SIGURJONSSON GUDMUNDER FERTRAM

Inventor： KELLY ROBERT JAMES ,  MARSH CLIVE ,  ALI MOHAMMAD AZAM ,  SIGURJONSSON GUDMUNDER FERTRAM

IPC: A61K9/70 ,  A61K38/00

CPC classification number: A61L15/425 ,  A61L15/32 ,  A61L15/64 ,  C08H1/00 ,  C08L89/00

Abstract: The invention relates to a porous keratin construct material comprising keratin protein for use in wound healing applications. The porous keratin construct is capable of bio-absorbing into a wound to promote wound healing. The rate at which the construct bio-absorbs into the wound may be controlled altered by controlling the degree of disulfide cross-linking between the keratin proteins in the porous keratin construct. The invention is also related to a method of making the porous keratin construct.

Abstract translation: 本发明涉及包含用于伤口愈合应用的角蛋白蛋白的多孔角蛋白构建体材料。 多孔角蛋白构建体能够生物吸收到伤口中以促进伤口愈合。 可以通过控制多孔角蛋白构建体中的角蛋白质之间的二硫键交联程度来改变构建物生物吸收到伤口中的速率。 本发明还涉及制造多孔角蛋白构建体的方法。

公开(公告)号：JP2009001015A

公开(公告)日：2009-01-08

申请号：JP2008153644

申请日：2008-06-12

Applicant: Keratec Ltd ,  ケラテク リミテッド

Inventor： KELLY ROBERT JAMES ,  RANKIN DOUGLAS ALEXANDER ,  RODDICK-LANZILOTTA ALISA DAWN ,  BRYSON WARREN GLEN

IPC: B29C41/12 ,  B29K81/00 ,  B29L7/00 ,  C08H1/06 ,  C08J5/18 ,  C08J7/00 ,  C08J9/28 ,  C09J189/00 ,  D01F4/00

CPC classification number: C08J5/18 ,  C08H1/06 ,  C08J9/28 ,  C08J2201/048 ,  C08J2389/00 ,  D01F4/00 ,  Y10T428/14 ,  Y10T428/28 ,  Y10T428/2852

Abstract: PROBLEM TO BE SOLVED: To provide a protein thin film and a protein fiber manufactured from S-sulfonated keratin derivatives, and to provide a method of manufacturing the protein thin film and the protein fiber. SOLUTION: The method of manufacturing the protein thin film by performing solvent casting of an solution of S-sulfonated keratin protein, and the method of manufacturing the protein fiber by extruding a solution of S-sulfonated keratin into an aqueous solution containing a reductant and salts that causes the protein in the solution to become insoluble are provided. Further, the protein thin film and protein fiber manufactured by the method of manufacturing the protein thin film and protein fiber are also provided. COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 待解决的问题：提供由S-磺化角蛋白衍生物制造的蛋白质薄膜和蛋白质纤维，并提供制造蛋白质薄膜和蛋白质纤维的方法。 解决方案：通过溶剂浇铸S-磺化角蛋白溶液的方法制造蛋白质薄膜的方法，以及通过将S-磺化角蛋白溶液挤出到含有 提供使溶液中的蛋白质变得不溶的还原剂和盐。 此外，还提供了通过制造蛋白质薄膜和蛋白质纤维的方法制造的蛋白质薄膜和蛋白质纤维。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：CA2704774A1

公开(公告)日：2009-05-07

申请号：CA2704774

申请日：2008-10-31

Applicant: KERATEC LTD ,  WEBER JEFFREY A

Inventor： KELLY ROBERT JAMES ,  SCOTT SONYA MARY ,  RODDICK-LANZILOTTA ALISA DAWN ,  AITKEN STEVEN GEOFFREY

IPC: C07K14/435 ,  A61K8/65 ,  A61K38/17 ,  A61Q5/00 ,  A61Q19/00 ,  C07K1/107

Abstract: Soluble keratin derivatives are disclosed. The soluble keratin derivatives may include a soluble keratin protein having at least one substituted chemical group at a lysine group, terminal amine group and/or hydroxyl amino acid group of a soluble keratin protein. Soluble keratin derivatives may be formed by succinylation or quaternisation, or by reaction with fatty acid derivatives. The soluble keratin derivatives may be used in personal care formulations, and may also comprise mixtures of several different soluble keratin derivatives.

公开(公告)号：EP2099437A4

公开(公告)日：2013-06-19

申请号：EP07862718

申请日：2007-12-11

Applicant: KERATEC LTD ,  WEBER JEFFREY A

Inventor： KELLY ROBERT JAMES ,  MARSH CLIVE ,  ALI MOHAMMAD AZAM ,  SIGURJONSSON GUDMUNDER FERTRAM

IPC: A61K9/70 ,  A61K38/00 ,  C08H1/00

CPC classification number: A61L15/425 ,  A61L15/32 ,  A61L15/64 ,  C08H1/00 ,  C08L89/00

公开(公告)号：EP1534353A4

公开(公告)日：2010-10-13

申请号：EP03733659

申请日：2003-06-10

Applicant: KERATEC LTD

Inventor： PEPLOW PHILIP VICTOR ,  DIAS SUBASINGHE NISANKE GEORGE ,  RODDICK-LANZILOTTA ALISA DAWN ,  KELLY ROBERT JAMES

IPC: A61L27/00 ,  A61L27/22 ,  A61L27/46 ,  A61L27/56 ,  C08H1/06 ,  C08L89/04 ,  C08K3/32

CPC classification number: C08H1/06 ,  A61L27/227 ,  A61L27/46 ,  A61L27/56 ,  A61L2430/02 ,  C08L89/04

公开(公告)号：ZA201003290B

公开(公告)日：2011-02-23

申请号：ZA201003290

申请日：2010-05-10

Applicant: WEBER JEFFREY A ,  KERATEC LTD

Inventor： AITKEN STEVEN GEOFFREY ,  SCOTT SONYA MARY ,  RODDICK-LANZILOTTA ALISA DAWN ,  KELLY ROBERT JAMES

公开(公告)号：CA2451408C

公开(公告)日：2009-12-22

申请号：CA2451408

申请日：2002-07-17

Applicant: KERATEC LTD

Inventor： WORTH GILLIAN HELEN ,  RODDICK-LANZILOTTA ALISA DAWN ,  RANKIN DOUGLAS ALEXANDER ,  ELLIS GREGORY DAVID ,  SUMMERS CONAL GARTH ,  SINGLETON DIANE JOYCE ,  KELLY ROBERT JAMES ,  MESMAN PAUL JOHANNES ROY

IPC: B01D11/02 ,  C07K1/107 ,  C07K1/02 ,  C07K1/12 ,  C07K1/14 ,  C07K1/30 ,  C07K1/34 ,  C07K2/00 ,  C07K14/435 ,  C07K14/47

Abstract: A process for the preparation of soluble proteins of high molecular weight with little or no damage to the structural integrity of the proteins. The process is economically and environmentally acceptable by virtue of the cost of reagents that are used, and the recycling of some of those reagents, and is suitable for the production of soluble proteins on a large scale. The proces s includes a first stage using oxidative sulfitolysis followed by a second sta ge using mild conditions to extract the soluble protein. In the case of wool as the protein source the process leads to the production of soluble keratin proteins fractionated into the classes S-sulfonated keratin intermediate filament proteins and S-sulfontated keratin high sulfur proteins.

公开(公告)号：EA011388B1

公开(公告)日：2009-02-27

申请号：EA200601191

申请日：2004-12-16

Applicant: KERATEC LTD

Inventor： KELLY ROBERT JAMES ,  RODDICK-LANZILOTTA ALISA DOWN ,  ALI MOHAMMAD AZAM

IPC: A61L15/32 ,  A61K9/70 ,  A61K38/00 ,  A61K38/17 ,  A61K38/39 ,  A61L26/00 ,  A61P17/02

Abstract: Изобретениеотноситсяк способуполученияматериаладлялеченияран, включающемуполучение 10% растворабелкакератина, смешиваниебелкакератинас водорастворимымполимеромс образованиемоднороднойсмеси, отливкуводныйсмеси, полученнойтакимобразом, иследующиедругзадругомпроцессызамораживанияи оттаиванияс получениемгидрогеля. Визобретениитакжеописангидрогельдлялеченияран.

公开(公告)号：CA2672069A1

公开(公告)日：2008-06-12

申请号：CA2672069

申请日：2007-12-05

Applicant: KERATEC LTD ,  WEBER JEFFREY A

Inventor： KELLY ROBERT JAMES ,  MARSH CLIVE ,  ALI MOHAMMAD AZAM ,  VORWERK SIGRID EDITH

IPC: A61F13/00

Abstract: The invention relates to a material for use as bone void filler comprisin g soluble keratin protein. The material may be in the form of a putty, gel o r emulsion. Additional components may be added to the material to improve ha ndling characteristics and bone enhancement capabilities. The material may b e formulated to serve as a suitable carrier for demineralized bone matrix. T his invention also describes methods for making the material.

公开(公告)号：AU2007328181A1

公开(公告)日：2008-06-12

申请号：AU2007328181

申请日：2007-12-05

Applicant: KERATEC LTD ,  WEBER JEFFREY A

Inventor： VORWERK SIGRID EDITH ,  ALI MOHAMMAD AZAM ,  KELLY ROBERT JAMES ,  MARSH CLIVE

IPC: A61F13/00

Abstract: The invention relates to a material for use as bone void filler comprising soluble keratin protein. The material may be in the form of a putty, gel or emulsion. Additional components may be added to the material to improve handling characteristics and bone enhancement capabilities. The material may be formulated to serve as a suitable carrier for demineralized bone matrix. This invention also describes methods for making the material.