公开(公告)号：US09115395B2

公开(公告)日：2015-08-25

申请号：US14471346

申请日：2014-08-28

Applicant: Roche Molecular Systems, Inc.

Inventor： Joachim Wietzorrek

IPC: G01N15/06 ,  G01N33/00 ,  G01N33/48 ,  C12Q1/68 ,  G01N21/25 ,  G01N21/64 ,  G02B3/00

CPC classification number: C12Q1/686 ,  G01N21/253 ,  G01N21/6452 ,  G01N21/6486 ,  G01N2201/06146 ,  G01N2201/0806 ,  G02B3/00

Abstract: An apparatus for photometric measurement of biological liquids and a method of simultaneously measuring the presence or quantity of an analyte in a sample region are disclosed. The apparatus includes a plurality of spaced apart sample regions; a light source adapted to emit light including at least one frequency; a lens system including a light coupling system, wherein the light coupling system is disposed between the light source and the plurality of sample regions. A method is also disclosed including illuminating the sample region with a light beam emitted from a light source, wherein said light beam passes a light coupling system, the light coupling system including a telecentric element and a plurality of light mixing rods, wherein the light coupling system is disposed between the light source and the sample region such that the light beam is directed into the sample region.

Abstract translation: 公开了一种生物液体光度测量装置和同时测量样品区域中分析物的存在或量的方法。 该装置包括多个间隔开的样品区域; 适于发射包括至少一个频率的光的光源; 包括光耦合系统的透镜系统，其中所述光耦合系统设置在所述光源和所述多个样本区域之间。 还公开了一种方法，其包括用从光源发射的光束照射样品区域，其中所述光束通过光耦合系统，所述光耦合系统包括远心元件和多个光混合棒，其中所述光耦合 系统设置在光源和样品区域之间，使得光束被引导到样品区域中。

公开(公告)号：US20150064699A1

公开(公告)日：2015-03-05

申请号：US14471346

申请日：2014-08-28

Applicant: Roche Molecular Systems, Inc.

Inventor： Joachim Wietzorrek

IPC: C12Q1/68 ,  G01N21/64 ,  G02B3/00

CPC classification number: C12Q1/686 ,  G01N21/253 ,  G01N21/6452 ,  G01N21/6486 ,  G01N2201/06146 ,  G01N2201/0806 ,  G02B3/00

Abstract: An apparatus for photometric measurement of biological liquids and a method of simultaneously measuring the presence or quantity of an analyte in a sample region are disclosed. The apparatus includes a plurality of spaced apart sample regions; a light source adapted to emit light including at least one frequency; a lens system including a light coupling system, wherein the light coupling system is disposed between the light source and the plurality of sample regions. A method is also disclosed including illuminating the sample region with a light beam emitted from a light source, wherein said light beam passes a light coupling system, the light coupling system including a telecentric element and a plurality of light mixing rods, wherein the light coupling system is disposed between the light source and the sample region such that the light beam is directed into the sample region.

Abstract translation: 公开了一种生物液体光度测量装置和同时测量样品区域中分析物的存在或量的方法。 该装置包括多个间隔开的样品区域; 适于发射包括至少一个频率的光的光源; 包括光耦合系统的透镜系统，其中所述光耦合系统设置在所述光源和所述多个样本区域之间。 还公开了一种方法，其包括用从光源发射的光束照射样品区域，其中所述光束通过光耦合系统，所述光耦合系统包括远心元件和多个光混合棒，其中所述光耦合 系统设置在光源和样品区域之间，使得光束被引导到样品区域中。

公开(公告)号：US07999232B2

公开(公告)日：2011-08-16

申请号：US12520687

申请日：2007-12-21

Applicant: Andrew Colin Wilson ,  Sri Kumar Sandeep ,  Reece Wim Geursen

Inventor： Andrew Colin Wilson ,  Sri Kumar Sandeep ,  Reece Wim Geursen

IPC: G01N21/35

CPC classification number: G01N21/3504 ,  G01J3/4338 ,  G01N21/031 ,  G01N21/39 ,  G01N2021/3148 ,  G01N2021/399 ,  G01N2201/0221 ,  G01N2201/0612 ,  G01N2201/06146 ,  G01N2201/0694 ,  G01N2201/1211 ,  G01N2201/1247

Abstract: A gas detector (10) that is arranged to sense the concentration levels of target gases oxygen, methane, carbon monoxide, and hydrogen sulphide, within a gas sample from an environment surrounding the detector. The gas detector (10) comprises laser sources (12a-12d) that are arranged to transmit radiation through the gas sample at four target wavelengths that correspond approximately to the optimum absorption wavelengths of each of the target gases and an optical detector (16) that is arranged to sense the intensity of the radiation transmitted through the gas sample at each of the target wavelengths. A control system (22) generates representative concentration level information for the target gases based on the level of absorption of the radiation transmitted.

Abstract translation: 一种气体检测器（10），其被布置成感测来自环境周围环境的气体样品中的目标气体氧气，甲烷，一氧化碳和硫化氢的浓度水平。 气体检测器（10）包括激光源（12a-12d），其被布置成以四个目标波长透射通过气体样品的辐射，其大致对应于每个目标气体的最佳吸收波长;以及光学检测器（16）， 布置成感测在每个目标波长处透射通过气体样品的辐射的强度。 控制系统（22）基于所发射的辐射的吸收水平产生目标气体的代表性浓度水平信息。

公开(公告)号：US06377346B1

公开(公告)日：2002-04-23

申请号：US09398996

申请日：1999-09-17

Applicant: Mikko Väisälä ,  Jarmo Nurmi ,  Jarmo Korpi ,  Raimo Harju

Inventor： Mikko Väisälä ,  Jarmo Nurmi ,  Jarmo Korpi ,  Raimo Harju

IPC: G01N2127

CPC classification number: G01J3/08 ,  G01J3/021 ,  G01J3/0232 ,  G01J3/10 ,  G01N21/253 ,  G01N2201/06146 ,  G01N2201/0625

Abstract: An imaging device for biochemical or medical samples, the pulse mode light source of which incorporates flash lamps and a rotating mirror in an inclined position, the said mirror reflecting the light emitted by each flash lamp in turn along the same optical path to the sample. The flash lamps are switched on alternately in phases and synchronised with the rotating mirror and the emission light chopper, which comprises two rotating discs. The turning mirror directs the light at the sample from above and/or below, in which case a double-acting transparent scattering plate can be used.

Abstract translation: 用于生物化学或医学样品的成像装置，其脉冲模式光源包含闪光灯和倾斜位置的旋转镜，所述反射镜依次沿着与样品相同的光路反射每个闪光灯发射的光。 闪光灯交替地相互切换并与旋转镜和发射光斩波器同步，发射光斩波器包括两个旋转盘。 转向镜从上方和/或下方引导样品上的光，在这种情况下可以使用双作用透明散射板。

公开(公告)号：EP3040708A4

公开(公告)日：2016-08-31

申请号：EP14840555

申请日：2014-08-13

Applicant: FUJIFILM CORP

Inventor： ONO SHUJI

IPC: G01N21/47 ,  G01N21/55 ,  G01N21/59

CPC classification number: G01N21/4738 ,  G01N21/41 ,  G01N21/474 ,  G01N21/55 ,  G01N21/59 ,  G01N2021/4783 ,  G01N2201/06146 ,  G01N2201/08

公开(公告)号：EP2102633A4

公开(公告)日：2013-07-31

申请号：EP07866898

申请日：2007-12-21

Applicant: PHOTONIC INNOVATIONS LTD

Inventor： WILSON ANDREW COLIN ,  GEURSEN REECE WIM ,  SANDEEP SRI KUMAR

IPC: G01J3/433 ,  G01N21/03 ,  G01N21/31 ,  G01N21/35 ,  G01N21/39

CPC classification number: G01N21/3504 ,  G01J3/4338 ,  G01N21/031 ,  G01N21/39 ,  G01N2021/3148 ,  G01N2021/399 ,  G01N2201/0221 ,  G01N2201/0612 ,  G01N2201/06146 ,  G01N2201/0694 ,  G01N2201/1211 ,  G01N2201/1247

Abstract: A gas detector (10) that is arranged to sense the concentration levels of target gases oxygen, methane, carbon monoxide, and hydrogen sulphide, within a gas sample from an environment surrounding the detector. The gas detector (10) comprises laser sources (12a-12d) that are arranged to transmit radiation through the gas sample at four target wavelengths that correspond approximately to the optimum absorption wavelengths of each of the target gases and an optical detector (16) that is arranged to sense the intensity of the radiation transmitted through the gas sample at each of the target wavelengths. A control system (22) generates representative concentration level information for the target gases based on the level of absorption of the radiation transmitted.

Abstract translation: 气体检测器（10），其布置成感测来自环境周围环境的气体样品中的目标气体氧气，甲烷，一氧化碳和硫化氢的浓度水平。 气体检测器（10）包括激光源（12a-12d），其被设置为以四个目标波长透射通过气体样品的辐射，其大致对应于每个目标气体的最佳吸收波长;以及光学检测器（16）， 布置成感测在每个目标波长处透射通过气体样品的辐射的强度。 控制系统（22）基于所发射的辐射的吸收水平，生成目标气体的代表性浓度水平信息。

公开(公告)号：EP2220485A1

公开(公告)日：2010-08-25

申请号：EP08854001.8

申请日：2008-11-20

Applicant: EADS Deutschland GmbH

Inventor： GÖBEL, Johann ,  PEUSER, Peter

IPC: G01N33/00 ,  G01N21/64 ,  G01N21/35 ,  G01N27/62

CPC classification number: G01N21/64 ,  G01N21/031 ,  G01N21/35 ,  G01N21/3563 ,  G01N2201/06146 ,  G01N2201/0697

Abstract: The invention relates to a multi-sensor laser system (1) for the selective trace analysis of organic material, the multi-sensor system having at least one laser ion mobility spectrometer (2), an absorption spectrometer (3) and a fluorescent measuring device (4). The system is characterised in that it is equipped with a device (8) for the simultaneous generation of a common laser beam (14) with different wavelengths and pulses for the simultaneous operation of the laser ion mobility spectrometer (2), the absorption spectrometer (3) and the fluorescent measuring device (4). This avoids the disadvantages of the known solutions in prior art and provides an improved solution for the highly sensitive and highly selective trace analysis of organic material, in particular hazardous substances such as explosives and warfare agents in the air.

公开(公告)号：EP0987540B1

公开(公告)日：2008-08-20

申请号：EP99660148.0

申请日：1999-09-17

Applicant: WALLAC OY

Inventor： Väisälä, Mikko ,  Korpi, Jarmo ,  Nurmi, Jarmo ,  Harju, Raimo

IPC: G01N21/64 ,  G01N21/47 ,  G01N21/66 ,  G01N21/76

CPC classification number: G01J3/08 ,  G01J3/021 ,  G01J3/0232 ,  G01J3/10 ,  G01N21/253 ,  G01N2201/06146 ,  G01N2201/0625

公开(公告)号：EP2220485B1

公开(公告)日：2018-08-01

申请号：EP08854001.8

申请日：2008-11-20

Applicant: Spherea GmbH

Inventor： GÖBEL, Johann ,  PEUSER, Peter

IPC: G01N33/00 ,  G01N21/64 ,  G01N21/35 ,  G01N27/62

CPC classification number: G01N21/64 ,  G01N21/031 ,  G01N21/35 ,  G01N21/3563 ,  G01N2201/06146 ,  G01N2201/0697

公开(公告)号：EP2823287A1

公开(公告)日：2015-01-14

申请号：EP13707633.7

申请日：2013-03-05

Applicant: Biosurfit, S.A.

Inventor： DE OLIVEIRA GARCIA DA FONSECA, Joao Manuel

IPC: G01N21/55

CPC classification number: G01N33/54373 ,  G01N21/41 ,  G01N21/553 ,  G01N33/54346 ,  G01N33/553 ,  G01N2201/0612 ,  G01N2201/06146 ,  G01N2201/0621 ,  G01N2201/0635 ,  G01N2201/12723

Abstract: The disclosure relates to processing SPR signals, in particular signals obtained by illuminating a conductive surface with light at two wavelengths. Embodiments involve processing a first and second signal indicative of an intensity of light, received from a conductive layer at which SPR has occurred, as a function of angle of incidence, reflection or diffraction at the layer (depending on whether the incident light beam is received by a detector recording it in reflection or transmission from the conductive layer). The first and second signals each have two dips corresponding to a respective wavelength of the light at a respective angle at which surface plasmon resonance occurs for the respective wavelength and a peak between the two dips. The processing includes deriving a first and second value of a quantity indicative of signal magnitudes in the region of the peak. The method then provides for comparing the first and second values to detect a change in refractive index at the layer after the first signal and before the second signal was captured.

Abstract translation: 本公开涉及处理SPR信号，特别是通过用两个波长的光照射导电表面而获得的信号。 处理SPR信号可以涉及处理表示从已经发生SPR的导电层接收的光的强度的第一和第二信号作为该层上的入射角，反射或衍射的函数。 第一和第二信号各自具有对应于在相应波长的光的相应波长处的两个倾斜，在该角度处，对于相应波长发生表面等离子体共振并且在两个下降之间产生峰值。 该处理包括导出指示峰值区域中的信号幅度的量的第一值和第二值。 可以比较第一和第二值以检测第一信号之后的层和第二信号被捕获之前的折射率的变化。