公开(公告)号：WO1991015997A1

公开(公告)日：1991-10-31

申请号：PCT/US1991002707

申请日：1991-04-19

Applicant: CLINICAL TECHNOLOGIES ASSOCIATES, INC.

Inventor： CLINICAL TECHNOLOGIES ASSOCIATES, INC. ,  STEINER, Solomon, S. ,  ALBALA, Bruce, J. ,  FELDSTEIN, Robert

IPC: A61B05/103

CPC classification number: A61B5/0017 ,  A61B5/11 ,  A61B5/1123 ,  A61B5/1128 ,  A61B5/6892

Abstract: A system using audio and visual information to count coughs or evaluate other discrete information, including respiration and heart rate, relating to a patient in a fixed location such as a bed (46) is disclosed. The system provides movement- and sound-based information derived from the patient's activities to a storage device (26) and subsequently to a signal processing apparatus. One embodiment of the invention includes a pressure transducer (14), a video camera (18), a directional microphone (22), and a videocassette recorder (VCR) having two audio channels. Signals obtained from the transducer (14) and microphone (22) are transmitted to the two audio channel inputs of the VCR, while movement of the patient is recorded using the video camera (18) connected to the video channel input of the VCR. Part or all of the information stored using the VCR may be transmitted to signal processing equipment and frequency filtered to determine the presence and number of coughs, and any remaining information (e.g. the video data) may be used to confirm the count. Because various conditions manifest themselves in movements having different frequency characteristics, the present system, as appropriately modified, also can be used to determine the presence of symptoms such as restlessness and thereby evaluate the effectiveness of medicines such as sedatives and hypnotics.

公开(公告)号：WO1991007133A1

公开(公告)日：1991-05-30

申请号：PCT/US1990006747

申请日：1990-11-16

Applicant: N.K. BIOTECHNICAL ENGINEERING COMPANY

Inventor： N.K. BIOTECHNICAL ENGINEERING COMPANY ,  KOVACEVIC, Nebojsa ,  DELLON, A., Lee

IPC: A61B05/103

CPC classification number: A61B5/4827

Abstract: A sensing device (10) has prongs (15 and 16) used for determining the sensory responses of the human skin to evaluate the fiber-receptor nervous system of the human body, primarily in connection with the measurement of the ability to discriminate separate points of touch of the hand. The sensing device includes flexure straps (24B, 25B) which support the prongs (15, 16) and strain gage sensors (54, 55) to determine the displacement, or force, acting on individually mounted prongs or pins (15, 16) which are positioned to engage and apply a load to a human body. The sensors (54, 55) provide not only the load individually of each of the prongs (15, 16), but also the average load applied to the surface of the human body by the two prongs (15, 16).

公开(公告)号：WO1997036543A1

公开(公告)日：1997-10-09

申请号：PCT/US1997005239

申请日：1997-03-31

Applicant: RUSH-PRESBYTERIAN-ST. LUKE'S MEDICAL CENTER

Inventor： RUSH-PRESBYTERIAN-ST. LUKE'S MEDICAL CENTER ,  SANDLER, Richard, H. ,  MANSY, Hussein, A.

IPC: A61B05/103

CPC classification number: A61B7/008

Abstract: A method and apparatus for characterizing gastrointestinal sounds include a microphone array (12) to be positioned on a body for producing gastrointestinal sound signals. The signals are digitized and their spectra and duration is determined by a processor (30). A characterization as to the state of the gastrointestinal tract is made on the basis of the spectra and duration of the sound or event.

Abstract translation: 用于表征胃肠道声音的方法和装置包括位于身体上用于产生胃肠道声音信号的麦克风阵列（12）。 信号被数字化，并且其光谱和持续时间由处理器（30）确定。 根据声音或事件的频谱和持续时间，对胃肠道状态进行表征。

公开(公告)号：WO1997017882A3

公开(公告)日：1997-05-22

申请号：PCT/IB1996001432

申请日：1996-11-14

Applicant: TAYLOR, Geoffrey, L. ,  DERKSEN, Grant, D.

IPC: A61B05/103

公开(公告)号：WO1997000643A1

公开(公告)日：1997-01-09

申请号：PCT/US1996010738

申请日：1996-06-20

Applicant: TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY ,  DONSKOY, Dimitri

Inventor： TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY

IPC: A61B05/103

CPC classification number: A61B5/4504

Abstract: The present invention provides an apparatus for non-invasive determination of bone mass, said apparatus having a platform for supporting a bone to be measured, a spring having a selected stiffness which connects the platform to a sensor capable of measuring vibration velocity and force, and a vibrating means connected to the sensor, wherein the vibrating means exposes the sensor, the spring and the platform to vibration so that vibration velocity and force can be measured by the sensor and the mass of the bone determined. A second apparatus for non-invasive determination of bone mass having a gripping means, a spring having a selected stiffness which connects the gripping means to a platform for positioning of a bone, a sensor capable of measuring vibration velocity and force which connects the platform to a vibrating means, and a vibrating means which vibrates the sensor, the platform, the spring, and the gripping means so the vibration velocity and force can be measured by the sensor is also provided. In addition, a method of non-invasively determining mass of a bone with these apparatuses is provided.

Abstract translation: 本发明提供了一种用于非侵入式确定骨量的装置，所述装置具有用于支撑待测骨骼的平台，具有将平台连接到能够测量振动速度和力的传感器的选定刚度的弹簧，以及 连接到所述传感器的振动装置，其中所述振动装置将所述传感器，所述弹簧和所述平台暴露于振动，从而可以通过所述传感器和所确定的骨的质量来测量振动速度和力。 用于非侵入式确定具有夹持装置的骨块的第二装置，具有将夹持装置连接到用于定位骨骼的平台的选定刚度的弹簧，能够测量将平台连接到的平台的振动速度和力的传感器 振动装置和振动装置，其使传感器，平台，弹簧和夹持装置振动，从而可以通过传感器测量振动速度和力。 此外，提供了一种使用这些装置非侵入性地确定骨质量的方法。

公开(公告)号：WO1996028092A1

公开(公告)日：1996-09-19

申请号：PCT/US1996002322

申请日：1996-03-11

Applicant: SAK, Robert, F.

IPC: A61B05/103

CPC classification number: A61B10/0291 ,  A61B2010/0216 ,  A61B2017/320012

Abstract: A cervical sampling system includes a vaginal insert tube (20), a removable swab sleeve (42), a sampling swab (14), and a stem (16) for pushing the swab (14) into contact with the cervical tissue. A kit using the sampling system for in-home PAP smear tests is also disclosed.

Abstract translation: 子宫颈取样系统包括阴道插入管（20），可移除的拭子套（42），取样拭子（14）和用于推动拭子（14）与子宫颈组织接触的杆（16）。 还公开了一种使用家用PAP涂片测试的采样系统的套件。

公开(公告)号：WO1996028091A1

公开(公告)日：1996-09-19

申请号：PCT/GB1996000582

申请日：1996-03-11

Applicant: UNIVERSITY OF BRIGHTON ,  TROKE, Michael

Inventor： UNIVERSITY OF BRIGHTON

IPC: A61B05/103

CPC classification number: A61B5/6833 ,  A61B5/1071 ,  A61B5/1116 ,  A61B5/411 ,  A61B5/4528 ,  A61B5/6823

Abstract: A pad (1, 11, 12) for attaching an apparatus (10), such as medical apparatus such as a goniometer for determining the motion of a joint or joints of a subject, to the subject. The pad (1, 11, 12) comprises a substrate (2) including an adhesive layer (3a, 3b) on one side of the substrate (2) for attaching the substrate (2) to the subject. On the other side of the substrate (2), a mounting means (4) is provided for supporting the apparatus (10). The pad also includes a counterbalance means (7) which is provided to offset the weight of the apparatus (10).

Abstract translation: 一种用于附接装置（10）的垫（1,11,12），例如用于确定受试者的关节或关节的运动的诸如测角器的医疗装置。 衬垫（1,11,12）包括在衬底（2）的一侧上包括用于将衬底（2）附接到对象的粘合剂层（3a，3b）的衬底（2）。 在基板（2）的另一侧，设置有用于支撑装置（10）的安装装置（4）。 该垫还包括平衡装置（7），该平衡装置（7）设置成抵消装置（10）的重量。

公开(公告)号：WO1995028880A1

公开(公告)日：1995-11-02

申请号：PCT/US1995004995

申请日：1995-04-24

Applicant: BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM

Inventor： BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM ,  ATHANASIOU, Kyriacos ,  CONSTANTINIDES, George ,  LANCTOT, Dan, R.

IPC: A61B05/103

CPC classification number: A61B5/4514 ,  A61B5/0053 ,  A61B5/103 ,  A61B5/224 ,  A61B5/4528 ,  G01N3/42 ,  G01N2203/0071 ,  G01N2203/0089 ,  G01N2203/0206 ,  G01N2203/0208 ,  G01N2203/0244 ,  G01N2203/0676

Abstract: This invention is an articular cartilage evaluator (110) for determining the index of structural integrity of articular cartilage. This computer based system measures deformation or reaction force of articular cartilage through closed loop control of a testing tip (122) and allows the measurement of peak force, stress relaxation behavior or creep behavior in vivo and in situ. The evaluator (110) also allows the calibration of the tissue's material properties. A calibrator (300) is also provided for calibrating the evaluator and removing a replaceable tip assembly (123).

Abstract translation: 本发明是用于确定关节软骨的结构完整性指数的关节软骨评估器（110）。 这种基于计算机的系统通过测试尖端（122）的闭环控制来测量关节软骨的变形或反作用力，并允许在体内和原位测量峰值力，应力松弛行为或蠕变行为。 评估器（110）还允许校准组织的材料特性。 还提供校准器（300），用于校准评估器并移除可替换的尖端组件（123）。

公开(公告)号：WO1995022282A1

公开(公告)日：1995-08-24

申请号：PCT/GB1995000313

申请日：1995-02-15

Applicant: BRITISH TECHNOLOGY GROUP LIMITED ,  DRAPER, Edward, Richard, Cornell

Inventor： BRITISH TECHNOLOGY GROUP LIMITED

IPC: A61B05/103

CPC classification number: A61B5/4504 ,  A61B5/1038 ,  A61B17/64

Abstract: The method involves having the subject (1), to whose fractured limb an external fixator (2) has been applied, undergo a specific load test, measuring the load carried by the fixator and the total load carried by the limb during the test, and determining a measure representing a comparison between the two measured loads. The test is preferably a dynamic one, and a suitable apparatus for carrying out the method is described, which includes a forceplate (4) incorporated in a treadmill assembly (2) to stimulate muscle activity in the limb during the test. The method and device provides an early indication as to whether or not bone healing has started, and thus can be used to provide an advance warning in cases of delayed osseous union.

Abstract translation: 所述方法包括：对已经施加有外固定器（2）的骨折肢体的受检者（1）进行特定的负荷试验，测量固定器承载的负荷和在试验期间由肢体携带的总载荷， 确定表示两个测量负载之间的比较的度量。 该测试优选是动态测试，并且描述了用于执行该方法的合适的设备，其包括结合在跑步机组件（2）中的刺激板（4），以在测试期间刺激肢体中的肌肉活动。 该方法和装置提供关于骨愈合是否已经开始的早期指示，并且因此可以用于在延迟骨结合的情况下提供预警。

公开(公告)号：WO1995014431A1

公开(公告)日：1995-06-01

申请号：PCT/US1994013280

申请日：1994-11-29

Applicant: ARCH DEVELOPMENT CORPORATION

Inventor： ARCH DEVELOPMENT CORPORATION ,  GIGER, Maryellen, L. ,  DOI, Kunio

IPC: A61B05/103

CPC classification number: G06T7/0012 ,  A61B6/4042 ,  A61B6/482 ,  A61B6/505 ,  A61B6/583 ,  G06T2207/10116 ,  G06T2207/30008 ,  G06T2207/30012

Abstract: A computerized method and system for the radiographic analysis of bone structure. Techniques include texture analysis for use in quantitating the bone structure and risk of fracture. Texture analysis of the bone structure incorporates directionality information, for example, in terms of the angular dependence of the RMS variation and first moment of the power spectrum of a ROI in a bony region. The system includes using dual energy imaging to obtain measures of both mass and bone structure with one exam. Specific applications are given for the analysis of regions within the vertebral bodies on conventional spine radiographs. Techniques include novel features that characterize the power spectrum of the bone structure and allow extraction of directionality features with which to characterize the spatial distribution and thickness of the bone trabeculae. These features are then merged using artifical neural networks in order to yield a likelihood of risk of future fracture.

Abstract translation: 一种用于骨结构射线照相分析的计算机化方法和系统。 技术包括用于定量骨结构和骨折风险的纹理分析。 骨骼结构的纹理分析包括方向性信息，例如，根据RMS变化的角度依赖性和在骨区域中的ROI的功率谱的第一时刻。 该系统包括使用双能量成像，通过一次考试获得质量和骨骼结构的测量。 给出了常规脊柱X光照片对椎体内部区域进行分析的具体应用。 技术包括表征骨骼结构的功率谱的新特征，并且允许提取用于表征骨小梁的空间分布和厚度的方向性特征。 然后，使用人造神经网络将这些特征合并，以产生未来骨折风险的可能性。