公开(公告)号：JP2007039451A

公开(公告)日：2007-02-15

申请号：JP2006187495

申请日：2006-07-07

Applicant: Saitama Daiichi Seiyaku Kk ,  埼玉第一製薬株式会社

Inventor： NOGUCHI KENICHI ,  KAKUBARI YASUHIRO

IPC: A61K47/32 ,  A61K9/70 ,  A61K47/02 ,  A61K47/04 ,  A61K47/08 ,  A61K47/14 ,  A61K47/18 ,  A61K47/34

Abstract: PROBLEM TO BE SOLVED: To provide a poultice having excellent adhesion and re-adhesion force for a long time, therefore, capable of applying a medicament to the skin for the long time, capable of being again adhered thereto, and having an excellent sense of use with suppleness and low irritation to the skin.
SOLUTION: This hydrous pressure-sensitive adhesive composition contains polybutene, a nonionic surfactant, and an oil-absorbing inorganic powder. The polybutene is mixed into the composition in an amount of more than 5.0 mass% and not more than 20.0 mass% based on a total amount of the hydrous pressure-sensitive adhesive composition.
COPYRIGHT: (C)2007,JPO&INPIT

Abstract translation: 待解决的问题：为了长时间地提供具有优异的粘合力和再粘合力的泥敷剂，因此能够长时间地将药物施加到皮肤上，能够再次粘附到其上，并且具有 优良的使用感与柔软性和对皮肤的低刺激性。 解决方案：该含水压敏粘合剂组合物含有聚丁烯，非离子表面活性剂和吸油性无机粉末。 相对于含水压敏粘合剂组合物的总量，将聚丁烯以大于5.0质量％且不大于20.0质量％的量混合到组合物中。 版权所有（C）2007，JPO＆INPIT

公开(公告)号：JP3809462B2

公开(公告)日：2006-08-16

申请号：JP2005507234

申请日：2004-06-17

Applicant: 埼玉第一製薬株式会社

Inventor： 孝行 小林 ,  尚久 川村 ,  英範 澤田

IPC: A61K9/70 ,  A61K45/00 ,  A61K47/10 ,  A61K47/14 ,  A61K47/32 ,  A61K47/34 ,  A61K47/44 ,  A61P9/12 ,  A61P19/00 ,  A61P37/08

CPC classification number: A61L24/046 ,  A61F2013/00663 ,  A61K9/7061 ,  A61K47/32 ,  Y10T156/1052

公开(公告)号：JP2006176502A

公开(公告)日：2006-07-06

申请号：JP2005341312

申请日：2005-11-28

Applicant: Dai Ichi Seiyaku Co Ltd ,  Saitama Daiichi Seiyaku Kk ,  埼玉第一製薬株式会社 ,  第一製薬株式会社

Inventor： KAKUBARI YASUHIRO ,  NOGUCHI KENICHI ,  IKEDA MIYUKI

IPC: A61K47/10 ,  A61K9/06 ,  A61K9/08 ,  A61K9/12 ,  A61K9/70 ,  A61P9/08 ,  A61P21/02 ,  A61P29/00

Abstract: PROBLEM TO BE SOLVED: To provide a medicinal preparation for external use, containing a refrigerant reduced in pungent odors such as a mint odor and exerting substantially no influence on the rate of percutaneous absorption of the medicinal ingredient.
SOLUTION: The medicinal preparation for external use comprises (1) a medicinal ingredient and (2) a refrigerant reduced in the mint odor and exerting substantially no influence on the rate of percutaneous absorption of the medicinal ingredient, such as 2-methyl-3-(1-menthyloxy)propane-1,2-diol or a derivative thereof.
COPYRIGHT: (C)2006,JPO&NCIPI

Abstract translation: 要解决的问题：提供一种外用药物制剂，其含有减少刺激性气味的制冷剂，如薄荷味，并且基本上不影响药用成分的经皮吸收速率。

解决方案：外用药物包括（1）药用成分和（2）减少薄荷味的制冷剂，对药用成分的经皮吸收速率基本上没有影响，例如2-甲基 -3-（1-甲基氧基）丙烷-1,2-二醇或其衍生物。 版权所有（C）2006，JPO＆NCIPI

公开(公告)号：JP2006070027A

公开(公告)日：2006-03-16

申请号：JP2005226074

申请日：2005-08-04

Applicant: Dai Ichi Seiyaku Co Ltd ,  Saitama Daiichi Seiyaku Kk ,  埼玉第一製薬株式会社 ,  第一製薬株式会社

Inventor： NAKAJIMA NORIKO ,  SHINKAI NORIHIRO ,  YAMAUCHI HITOSHI ,  KIKUCHI MASAHIKO

IPC: A61K31/439 ,  A61K9/06 ,  A61K9/08 ,  A61K9/12 ,  A61K9/20 ,  A61K9/70 ,  A61K47/10 ,  A61K47/14 ,  A61K47/18 ,  A61K47/30 ,  A61K47/32 ,  A61K47/34 ,  A61K47/36 ,  A61K47/38 ,  A61K47/42 ,  A61K47/46 ,  A61P1/02 ,  C07D497/20

Abstract: PROBLEM TO BE SOLVED: To provide a medicine used for prophylaxis and/or treatment of xerostomia, rapidly exhibiting excellent sialogogic effects and reducing or avoiding adverse effects on digestive organs.
SOLUTION: A medicine is used for, e.g. prophylaxis and/or treatment of the xerostomia. The medicine in the form of administration to the mucous membrane in the oral cavity comprises a spirooxathiolane-quinuclidine derivative represented by general formula (I) (wherein, R
1 and R
2 may each be the same or different and are each independently a hydrogen atom, an alkyl group, a cyclopentyl group, a cyclohexyl group, a monoaryl-substituted or a diaryl-substituted methylol group or an aryl-substituted alkyl group) or an acid addition salt thereof as an active ingredient.
COPYRIGHT: (C)2006,JPO&NCIPI

Abstract translation: 要解决的问题：提供用于预防和/或治疗口腔干燥症的药物，快速表现出优异的唾液酸作用并减少或避免对消化器官的不良影响。 解决方案：药物用于，例如， 预防和/或治疗口腔干燥症。 给予口腔粘膜形式的药物包括由通式（I）表示的螺硫硫杂环戊烷 - 奎宁环衍生物（其中，R 1 和R 2 可以各自相同或不同，各自独立地为氢原子，烷基，环戊基，环己基，单芳基取代的或二芳基取代的羟甲基或芳基取代的烷基）或酸加成 其盐作为活性成分。 版权所有（C）2006，JPO＆NCIPI

公开(公告)号：JP3708975B2

公开(公告)日：2005-10-19

申请号：JP8575894

申请日：1994-03-31

Applicant: 埼玉第一製薬株式会社 ,  富山化学工業株式会社

Inventor： 尚久 川村 ,  彰彦 楠

IPC: A61K9/70 ,  A61K31/54 ,  A61K31/5415 ,  A61K47/16 ,  A61K47/34 ,  A61K47/42 ,  A61P25/04 ,  A61P29/00

公开(公告)号：JP2005015537A

公开(公告)日：2005-01-20

申请号：JP2003179165

申请日：2003-06-24

Applicant: Gantsu Kasei Kk ,  Saitama Daiichi Seiyaku Kk ,  ガンツ化成株式会社 ,  埼玉第一製薬株式会社

Inventor： KAWAMURA NAOHISA ,  SAWADA HIDENORI ,  KOBAYASHI TAKAYUKI

IPC: A61L15/58 ,  C09J7/02 ,  C09J133/00

Abstract: PROBLEM TO BE SOLVED: To provide a pressure-sensitive adhesive tape which enables incorporation of a large amount of a plasticizer into a pressure sensitive adhesive layer in the pressure sensitive adhesive tape obtained by laminating the pressure-sensitive adhesive layer on a substrate, excels in adhesiveness, cohesiveness, and stability, and does not cause skin irritation. SOLUTION: The pressure-sensitive adhesive tape is a removable pressure-sensitive adhesive tape obtained by coating an aqueous emulsion pressure-sensitive adhesive containing a copolymer obtained by polymerizing a (meth)acrylic monomer having an acetoacetyl group in the molecule and one or more (meth)acrylic monomers selected from the group consisting of 2-ethylhexyl acrylate, butyl acrylate, diacetoneacrylamide, methyl (meth)acrylate, ethylene glycol dimethacrylate, and tetraethylene glycol dimethacrylate together with a plasticizer on a substrate, and the pressure sensitive adhesive layer does not contain a percutaneously absorbing agent, and the copolymer is self-crossinked by the acetoacetyl group. COPYRIGHT: (C)2005,JPO&NCIPI

Abstract translation: 解决的问题：提供一种压敏粘合带，其能够将压敏粘合剂层层叠在基材上而获得的压敏粘合剂层中的大量增塑剂结合到压敏粘合剂层中 具有粘着性，凝聚力和稳定性，不会引起皮肤刺激。 解决方案：压敏粘合带是通过涂布含有通过在分子中聚合具有乙酰乙酰基的（甲基）丙烯酸单体而获得的共聚物的水性乳液压敏粘合剂而得到的可除去的压敏粘合带， 或更多的选自丙烯酸2-乙基己酯，丙烯酸丁酯，双丙酮丙烯酰胺，（甲基）丙烯酸甲酯，乙二醇二甲基丙烯酸甲酯和四甘醇二甲基丙烯酸酯的（甲基）丙烯酸单体以及增塑剂在基材上的压敏粘合剂 层不含经皮吸收剂，共聚物由乙酰乙酰基自交联。 版权所有（C）2005，JPO＆NCIPI

公开(公告)号：JP2003034634A

公开(公告)日：2003-02-07

申请号：JP2001252112

申请日：2001-07-19

Applicant: Saitama Daiichi Seiyaku Kk ,  埼玉第一製薬株式会社

Inventor： NAKAJIMA NORIKO

IPC: A61M37/00 ,  A61K9/70

Abstract: PROBLEM TO BE SOLVED: To provide a reservoir-type administrating device for administrating a liquid or gel preparation, which contains a medicinal drug, through the skin or the mucosa. SOLUTION: In the reservoir-type administrating device, a drug reservoir is provided between a base material film and a release-controlling film layer, and an adhesive layer and a peeling liner are laminated on the surface opposite to the face where the release-controlling film layer is bound with the base material film. In this case, a drug reservoir-coating film is provided between the drug reservoir and the release- controlling film to prevent the leakage of a drug-containing liquid from the drug reservoir during the storage of the device. Furthermore, the drug-containing liquid can flow out on the side of the release-controlling film when used, since a means for releasing the drug reservoir-coating film is provided. This reservoir-type administrating device of the present invention having the reservoir-coating film between the drug reservoir and the release-controlling film can prevent the drug-containing liquid or gel from leaking out of the drug reservoir on the side of the release-controlling film during the storage of the device of the present invention, and thereby the reduction in adhesive force of an adhesive agent, the leakage of the drug-containing liquid or gel and the volatilization of a solvent can be prevented.

Abstract translation: 要解决的问题：提供一种用于通过皮肤或粘膜施用含有药用药物的液体或凝胶制剂的储液型给药装置。 解决方案：在贮存型给药装置中，在基材膜和剥离控制膜层之间设置药物储存器，并且在与释放控制膜的面相反的表面上层压粘合剂层和剥离衬垫 膜层与基材膜结合。 在这种情况下，药物储存器涂层膜设置在药物储存器和释放控制膜之间，以防止药物储存器在储存装置期间从药物储存器泄漏。 此外，药物储存液体在使用时可以在释放控制膜的一侧流出，因为提供了用于释放药剂储存器涂膜的装置。 本发明的储液型给药装置在药剂储存器与释放控制膜之间具有储液膜的情况下，能够防止含药液体或凝胶从释放控制侧的药剂储存器漏出 在本发明的装置的储存期间，可以防止粘合剂的粘合力的降低，含药液体或凝胶的泄漏以及溶剂的挥发。