AGENT FOR SEDATING RESPONSE TO EXTERNAL STIMULATION IN SKIN AND METHOD FOR SEDATING THAT RESPONSE TECHNICAL FIELD
    44.
    发明申请
    AGENT FOR SEDATING RESPONSE TO EXTERNAL STIMULATION IN SKIN AND METHOD FOR SEDATING THAT RESPONSE TECHNICAL FIELD 审中-公开
    用于对皮肤外部刺激作出反应的试剂和用于评估反应技术领域的方法

    公开(公告)号:WO2015136718A1

    公开(公告)日:2015-09-17

    申请号:PCT/JP2014/057629

    申请日:2014-03-12

    CPC classification number: A61K31/716 A61K31/77 A61K36/738 A61K2300/00

    Abstract: An object of the present invention is to provide an agent for sedating the response of skin to external stimulation. The aforementioned object was achieved by finding a component that promotes CD39 gene expression in Langerhans cells. More specifically, the present invention is based on the finding that the combination of carboxymethyl-beta glucan or a salt thereof, polyoxyethylene (POE)/polyoxypropylene (POP) random copolymer dimethyl ether and rosewater promotes CD39 gene expression.

    Abstract translation: 本发明的目的是提供一种用于镇静皮肤对外部刺激的反应的药剂。 上述目的是通过在朗格汉斯细胞中发现促进CD39基因表达的成分来实现的。 更具体地说,本发明是基于羧甲基-β葡聚糖或其盐,聚氧乙烯(POE)/聚氧丙烯(POP)无规共聚物二甲醚和rosewater的组合促进CD39基因表达的发现。

    COSMETICS
    49.
    发明申请
    COSMETICS 审中-公开
    化妆品

    公开(公告)号:WO1997018793A1

    公开(公告)日:1997-05-29

    申请号:PCT/JP1996003442

    申请日:1996-11-22

    Abstract: Cosmetics having a UV shielding effect in a broad range from UV-B to UV-A and capable of preventing erythema and melanosis due to sunburn. Cosmetics containing conventional particulates titanium dioxide cannot exhibit a sufficient UV prevention effect and involve the problems that they are uncomfortable to the touch and are apt to give a dusty finish. The cosmetics of the invention contain spindle-shaped fine titanium dioxide particles having a mean minor axis of 0.03 to 0.06 mu m, a mean major axis of 0.08 to 0.12 mu m and an aspect ratio (major axis/minor axis) of 2 to 4 alone or together with metal oxides having a mean particle diameter of at least 0.2 mu m.

    Abstract translation: 化妆品在UV-B到UV-A的广泛范围内具有紫外线屏蔽效果,并且能够防止由于晒伤引起的红斑和黑色素沉积。 含有常规颗粒二氧化钛的化妆品不能表现出足够的防紫外线效果,并且涉及到它们触摸不舒服并且易于产生灰尘的问题。 本发明的化妆品含有平均短径为0.03〜0.06μm,平均长径为0.08〜0.12μm,长径比(长轴/短轴)为2〜4的纺锤状的二氧化钛微粒 单独或与平均粒径为至少0.2μm的金属氧化物一起。

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