公开(公告)号：US20170252131A1

公开(公告)日：2017-09-07

申请号：US15512841

申请日：2014-09-19

Applicant: Stichting VU-VUMC

Inventor： Daniel KOOPS

IPC: A61C8/00 ,  A61C1/08

Abstract: The present invention provides a kit for use for the implantation of a dental implant, comprising an implant guide comprising a proximal end and a distal end, wherein the distal end is configured to be detachably attached to a dental implant, said implant guide comprising a cylindrical body, wherein the cylindrical body comprises a cylindrical outer surface and a circumferential groove in the outer surface, and a template configured to be arranged at a predetermined location with respect to a jaw, wherein the template comprises at least one implantation channel to guide the cylindrical body of the implant guide in a desired implantation direction during implantation of a dental implant in the jaw, and a stop surface at an end of the implantation channel.The kit comprises a stop element comprising a first part and a second part, wherein the first part and the second part are configured to be movable between a first state, in which the first part and the second part are spaced at a first distance, and a second state, in which the first part and the second part are spaced at a second distance, wherein the first distance is smaller than the second distance, and wherein the first and second parts are biased to the first state, wherein the second distance is the same or larger than a distance between diametrically opposite sides of the outer surface of the implant guide, such that, before implantation, the first part and the second part can be arranged, in the second state, on diametrically opposite sides of the outer surface, and that during movement in the implantation direction of the dental implant into the jaw, the stop surface of the implantation channel will push the stop element towards the groove until the groove will allow the first and second part to move towards the first state and the stop element will be caught by the groove, therewith blocking further movement of the implant guide in the implantation direction.

公开(公告)号：US20160212729A1

公开(公告)日：2016-07-21

申请号：US14896610

申请日：2014-06-06

Applicant: STICHTING VU-VUME ,  FOMNIKHEF

Inventor： Henk Jan Bulten ,  Johannes Francisc Josephina VAN DEN BRAND

IPC: H04W72/00 ,  H04B7/26 ,  H04W52/02 ,  H04W72/04

CPC classification number: H04W72/005 ,  H04B7/2656 ,  H04W52/0216 ,  H04W72/0446 ,  H04W72/048 ,  H04W84/18 ,  Y02D70/00 ,  Y02D70/144 ,  Y02D70/162 ,  Y02D70/164 ,  Y02D70/22 ,  Y02D70/449

Abstract: A method for managing communication in a wireless mesh network comprising a plurality of wireless nodes and a wireless node for use in such network are described, wherein said method may comprise: providing a time slot schedule (frame), preferably a TDMA time slot schedule (frame), comprising one or more time slots, including a transmission time slot enabling a node to transmit a broadcast message, a reception time slot enabling a node to receive a broadcast message from one or more other nodes; and/or a sleep time slot for configuring said node in an idle state; and, assigning said time slots to nodes in said network on the basis of the position of said nodes in said network.

Abstract translation: 描述了一种用于管理无线网状网络中的通信的方法，该无线网状网络包括用于这种网络的多个无线节点和无线节点，其中所述方法可以包括：提供时隙调度（帧），优选地，TDMA时隙调度 帧），包括一个或多个时隙，包括使得节点能够发送广播消息的传输时隙;使得节点能够从一个或多个其他节点接收广播消息的接收时隙; 和/或用于将所述节点配置为空闲状态的休眠时隙; 并且基于所述网络中的所述节点的位置，将所述时隙分配给所述网络中的节点。

公开(公告)号：US20160138095A1

公开(公告)日：2016-05-19

申请号：US14898112

申请日：2014-06-11

Applicant: Stichting VU-VUMC

Inventor： Erwin Johannes Gerard Peterman ,  Gijs Jan Lodewijk Wuite ,  Gerrit Sitters ,  Douwe Kamsma

IPC: C12Q1/68 ,  G01N29/06

CPC classification number: C12Q1/6837 ,  G01N29/0681 ,  G02B21/32

Abstract: A molecular manipulation system for investigating molecules, having a sample holder constructed to hold a sample comprising a plurality of molecules attached on one side to a surface in the sample holder and on another side attached to a microbead of a plurality of microbeads. The system having; an acoustic wave generator to generate an acoustic wave exerting a force on the microbeads in the sample; and a detector device to detect a response of the plurality of microbeads in the sample on the force exerted by the acoustic wave to investigate the molecules attached to the microbeads.

Abstract translation: 一种用于调查分子的分子操纵系统，具有样品架，其被构造成将包含附着在一侧的多个分子的样品保持在样品保持器中的表面上，另一侧附着在多个微珠的微珠上。 系统有 声波发生器，用于产生在样品中的微珠上施加力的声波; 以及检测器装置，用于检测样品中的多个微珠对由声波施加的力的响应，以研究附着于微珠的分子。

公开(公告)号：EP4312005A1

公开(公告)日：2024-01-31

申请号：EP22187745.9

申请日：2022-07-29

Applicant: Stichting VU ,  Stichting Nederlandse Wetenschappelijk Onderzoek Instituten ,  Universiteit van Amsterdam ,  Rijksuniversiteit Groningen ,  ASML Netherlands B.V.

Inventor： DEN BOEF, Arie, Jeffrey ,  VAN SCHAIJK, Theodorus, Thomas, Marinus ,  SETIJA, Irwan, Dani ,  Cromwijk, Tamara, Christina ,  ADHIKARY, Manashee ,  VAN KRAAIJ, Markus, Gerardus, Martinus, Maria

IPC: G01J3/02 ,  G01J3/453 ,  G01J3/36

Abstract: Disclosed is a Fourier-transform spectrometer comprising a beamsplitting arrangement operable to define a first radiation source and a second radiation source from a common radiation source, and at least one detector operable to detect interferogram data as a function of detection position in at least a first detection plane direction of a detection plane, the interferogram data resulting from interference of a first diverging beam emitted from said first radiation source and a second diverging beam emitted from said second radiation source. A processor is operable to:
perform a linearization correction to said interferogram data to obtain linearized interferogram data; and Fourier transform the linearized interferogram data to obtain spectral characteristic data relating to the common radiation source.

公开(公告)号：EP4246231A1

公开(公告)日：2023-09-20

申请号：EP22163109.6

申请日：2022-03-18

Applicant: Stichting VU ,  Stichting Nederlandse Wetenschappelijk Onderzoek Instituten ,  Universiteit van Amsterdam ,  ASML Netherlands B.V.

Inventor： DEN BOEF, Arie, Jeffrey ,  VAN SCHAIJK, Theodorus, Thomas, Marinus ,  BUIJS, Robin, Daniel ,  DE BOER, Johannes, Fitzgerald ,  MESSINIS, Christos

IPC: G03F7/20 ,  G01N21/21 ,  G03H1/04

Abstract: A method for determining a vertical position of a structure on a substrate with respect to a nominal vertical position is disclosed. The method comprises obtaining complex field data relating to scattered radiation from said structure, for a plurality of different wavelengths, determining variation in a phase parameter with wavelength from said complex field data; and determining said vertical position with respect to a nominal vertical position from the determined variation in phase with wavelength.

公开(公告)号：EP4238970A1

公开(公告)日：2023-09-06

申请号：EP22159896.4

申请日：2022-03-03

Applicant: InterAx Biotech AG ,  Stichting VU

Inventor： RIEMENS, Rick ,  BOSMA, Reggie ,  LEURS, Rob ,  DE ESCH, Iwan ,  WIJTMANS, Maikel ,  VISSCHER, Henry ,  NIKOLAEV, Yaroslav ,  KANEV, Georgi ,  ZIMMERMANN, Mirjam ,  RIZK, Aurélien ,  POTENZA, Alessandro ,  STEPNIEWSKI, Tomasz Maciej

IPC: C07D413/06 ,  A61P35/00

Abstract: The present disclosure relates to compounds of formula (I) comprising a (4-piperidinylmethyl) carboxamide moiety, which can act as modulators of ACKR3. The present disclosure also relates to the use of these compounds as a drug.

公开(公告)号：EP4063380A1

公开(公告)日：2022-09-28

申请号：EP21164713.6

申请日：2021-03-24

Applicant: Stichting VU

Inventor： GROSSMANN, Tom Norbert ,  WENDT, Mathias ,  EFREM, Nina-Louisa ,  BELLAVITA, Rosa ,  VAN RAMSHORST, Thirza ,  GERBER, Alan

IPC: C07K7/54 ,  A61K38/00 ,  C07K14/00

Abstract: The invention relates to a cyclic peptide comprising the amino acid sequence N-terminal-X 4 X 3 X 2 X 1-a -Y 1 Y 2 Y 3 Y 4 -C-terminal, wherein -a- represents a linker, and wherein the peptide comprises a linker -c- between the N-terminal amino acid and C-terminal amino acid, and/or wherein the two amino acids of one or two of the following amino acid pairs form a side chain-to-side chain bridged di-amino acid forming a bridge -b-: X 1 and Y 1 ; X 2 and Y 2 ; X 3 and Y 3 ; and X 4 and Y 4 . The invention further relates to the use of said cyclic peptide as a medicament, especially for inhibiting or preventing a Wingless/integrase-1 (Wnt)-dependent disease in an individual in need thereof.

公开(公告)号：EP3796089A1

公开(公告)日：2021-03-24

申请号：EP19203613.5

申请日：2019-10-16

Applicant: ASML Holding N.V. ,  ASML Netherlands B.V. ,  Stichting Nederlandse Wetenschappelijk ,  Stichting VU ,  Universiteit van Amsterdam

Inventor： MEHTA, Nikhil ,  KOOLEN, Armand Eugene Albert ,  KREUZER, Justin ,  WARNAAR, Patrick ,  TENNER, Vasco Tomas

IPC: G03F7/20 ,  G01N21/956

Abstract: Disclosed is a method for a metrology measurement on an area of a substrate comprising at least a portion of a target structure. The method comprises receiving a radiation information representing a portion of radiation scattered by the are, and using a filter in a Fourier domain for removing or suppressing at least a portion of the received radiation information that does not relate to radiation that has been scattered by the target structure for obtaining a filtered radiation information for the metrology measurement, wherein characteristics of the filter are based on target information about the target structure.

公开(公告)号：EP3605230A1

公开(公告)日：2020-02-05

申请号：EP18186825.8

申请日：2018-08-01

Applicant: Stichting VU ,  Stichting Nederlandse Wetenschappelijk Onderzoek Instituten ,  Universiteit van Amsterdam ,  ASML Netherlands B.V.

Inventor： TINNEMANS, Patricius Aloysius Jacobus ,  WARNAAR, Patrick ,  TENNER, Vasco Tomas

IPC: G03F7/20

Abstract: Disclosed is a method for obtaining a computationally determined interference electric field describing scattering of radiation by a pair of structures comprising a first structure and a second structure on a substrate. The method comprises determining a first electric field relating to first radiation scattered by the first structure; determining a second electric field relating to second radiation scattered by the second structure; and computationally determining the interference of the first electric field and second electric field, to obtain a computationally determined interference electric field.

公开(公告)号：EP3531191A1

公开(公告)日：2019-08-28

申请号：EP18158745.2

申请日：2018-02-27

Applicant: Stichting VU ,  ASML Netherlands B.V. ,  Universiteit van Amsterdam ,  Stichting Nederlandse Wetenschappelijk Onderzoek Instituten

Inventor： TENNER, Vasco, Tomas ,  TINNEMANS, Patricius, Aloysius, Jacobus

IPC: G02B27/42 ,  G03F7/20 ,  G03H1/04

Abstract: Disclosed is a method and associated apparatus for measuring a characteristic of interest relating to a structure on a substrate. The method comprises calculating a value for the characteristic of interest directly from the effect of the characteristic of interest on the phase of illuminating radiation when scattered by the structure, subsequent to illuminating said structure with said illuminating radiation.