Abstract:
PURPOSE: A method for preparing a water-insoluble gel composition is provided to minimize molecular weight reduction of polysaccharides using a small amount of a crosslinking agent and to ensure excellent strength and stability. CONSTITUTION: A method for preparing a water-insoluble gel composition comprises: a step of mixing water-soluble polysaccharides, an epoxy crosslinking agent, a basic compound, and a solvent; and a step of drying the mixture under vacuum at 1-30 deg. C to remove the solvent. The vacuum pressure is 1-30 mmHg. The solvent is removed by concentrating the water soluble polysaccharides in a concentration of 50-99 wt%. The molecular weight of the water soluble polysaccharides is 500-5,000 kDa. [Reference numerals] (AA) Volume of gel(%); (BB) Example 11
Abstract:
PURPOSE: A formulation containing a Gardenia jasminodes extract as an active ingredient is provided to promote Wnt/beta-catenin signal transduction, to regenerate skin, to ensure excellent wound healing effect, to prevent hair loss, and to enhance hair growth. CONSTITUTION: A skin regeneration promoting agent contains a Gardenia jasminodes extract as an active ingredient. A papilla activation promoting agent contains the extract as an active ingredient. The skin regeneration promoting agent promotes wound healing. The promoting agents contain 0.01-10 wt% of the Gardenia jasminodes extract and activate Wnt signal. A cosmetic composition and a pharmaceutical composition contain the promoting agents. [Reference numerals] (AA) Negative control group; (BB) Valproic acid; (CC) Gardenia jasminodes
Abstract:
PURPOSE: A composition containing a Prunus mume extract for relieving skin irritation is provided to relieve skin irritation such as skin dryness, erythema, keratoderma, itching, or burning sensation. CONSTITUTION: A composition for relieving skin irritation contains a Prunus mume extract. The composition relieves skin dryness, erythema, keratoderma, itching, or burning sensation due to skin irritation. The skin irritation is caused by retinoid or surfactant. [Reference numerals] (AA) IL-6 concentration(pg/ml); (BB) No treatment; (CC,EE) Prunus mume treatment(%); (DD) Retinoic acid(10uM);
Abstract:
PURPOSE: A cosmetic composition containing tranexamic acid and nicotinic acid amide is provided to effectively suppress melanocyte formation and to prevent or treat pigmentation. CONSTITUTION: A melanogenesis inhibitor contains 0.001-10 wt% of tranexamic acid and 0.001-10 wt% of nicotinic acid amide as active ingredients. The melanogenesis inhibitor further contains alpha- or beta-hydroxy acid. The alpha-hydroxy acid is glycolic acid, lactic acid, malic acid, citric acid, or tartaric acid. The beta-hydroxy acid is beta-hydroxybutyric acid, beta-hydroxy beta-methylbutyrate, carnitine, 3-hydroxypropionic acid, or salicylic acid. A cosmetic composition contains the melanogenesis inhibitor as an active ingredient.
Abstract:
PURPOSE: A composition containing valproic acid or pharmaceutically acceptable salt thereof is provided to promote growth of nail or toenail of a person with nail disorder. CONSTITUTION: A composition for promoting nail or toenail contains valproic acid or pharmaceutically acceptable salt thereof as an active ingredient. The valproic acid or pharmaceutically acceptable salt is sodium valproate. The composition is an external use formulation. A pharmaceutical composition contains the composition. A cosmetic composition contains the composition.
Abstract:
본 발명은 엘라직산(Ellagic acid) 또는 그 유도체를 함유하는 발모증진 또는 탈모억제 효능을 갖는 모발용 조성물에 대한 것이다. 보다 구체적으로, 엘라직산 또는 그 유도체를 함유함으로써 TGF-β에 의한 모낭에서 각질형성세포의 세포사멸을 효과적으로 억제함으로써 탈모를 억제하고 발모를 증진시킬 수 있는 조성물에 대한 것이다. 엘라직산, 발모, 탈모방지, TGF-β, 모낭
Abstract:
PURPOSE: An external use skin composition containing Prunus mume extract for care after laser surgical operation is provided to prevent skin sensitivity and to ensure moisturizing. CONSTITUTION: An external use skin composition for care after surgical operation contains 0.001-10 wt% of Prunus mume extract as an active ingredient. The composition is used for relieving skin irritation and pain or for recovering skin barriers. A cosmetic composition contains the external use skin composition. The cosmetic composition is used in the form of a solution, suspension, paste, emulsion, gel, lotion, cream, essence, pack, soothing mask, local patch, makeup base, moisturizing oil, powder, soap, surfactant-containing cleansing, oil, powder foundation, emulsion foundation, wax foundation, water in oil type or oil in water type, or spray.
Abstract:
PURPOSE: A cosmetic composition containing lactic acid derivative and urea is provided to remarkably moisturize with effects of removing keratin and enhancing moisture. CONSTITUTION: A cosmetic composition for moisturizing contains 1-weight% of urea and lactic acid derivative. The lactic acid derivative is potassium lactate, zinc lactate, calcium lactate, potassium lactate, magnesium lactate, copper lactate, manganases lactate, boron lactate or ammonium lactate. The composition is used for treating aged skin and keratinized skin for the old people.
Abstract:
A cosmetic composition for skin moisturization, which contains Criste Marine stem cell media extract is provided to specifically activate p63 which regulates the activation of skin stem cell and have skin moisturization. A cosmetic composition for skin moisturization comprises a Criste Marine stem cell media extract as an active ingredient. The composition activates epidermal stem cells. The cosmetic composition is used in the form of emulsion, cream, essence, pack, gel, powder, makeup base, foundation, lotion, ointment, cleansing foam, cleansing water, body lotion, body cream, body oil, rinse, soap or spray.
Abstract:
본 발명은 프럭토스 1,6-디포스페이트(D-fructose 1,6-diphosphate) 또는 그 유도체를 유효성분으로 함유하여 피부의 건조증상을 개선함을 특징으로 하는 피부외용제 조성물에 관한 것으로, 보다 상세하게는 피부세포의 분화를 촉진하여 새로운 각질의 재생산을 돕고, 피부에 보습기능을 담당하고 있는 천연보습인자(natural moisturizing factor, NMF)를 생산하고, 피부 내부로부터 수분유지에 필요한 지질의 합성을 증가시킴으로써, 피부의 수분함유능력 증강, 피부 건조의 방지, 그리고 아토피(atopy) 및 접촉성 피부염 증상의 예방, 개선 또는 치료에 효과가 있는 프럭토스 1,6-디포스페이트 또는 그 유도체를 함유하는 피부 외용제 조성물에 관한 것이다. 프럭토스 1,6-디포스페이트(D-fructose 1,6-diphosphate) * 보습 * 각질형성세포 분화 * 필라그린 * 지질생합성 * 세라마이드 * 천연보습인자 * 피부건조 * 아토피 * 접촉성 피부염