公开(公告)号：KR1020140111184A

公开(公告)日：2014-09-18

申请号：KR1020130025136

申请日：2013-03-08

Applicant: 대한민국(농촌진흥청장)

Inventor： 이승은 ,  김금숙 ,  노형준 ,  이정훈 ,  최재훈 ,  이대영 ,  김승유 ,  성정숙 ,  장인복 ,  김재룡

IPC: A61K36/28 ,  A61P17/00 ,  A61P19/02 ,  A61P9/10

Abstract: The present invention relates to a composition comprising a Synurus deltoides (Aiton) Nakai extract for inhibiting cell aging. The composition, comprising the Synurus deltoides (Aiton) Nakai extract having an excellent effect of inhibiting cell aging as an active ingredient, can be used for preventing age-related diseases, such as skin aging, rheumatoid arthritis, osteoarthritis, hepatitis, chronic damage to skin tissues, arteriosclerosis, prostatic hyperplasia, or liver cancer.

Abstract translation: 本发明涉及包含用于抑制细胞衰老的Synurus deltoides（Aiton）Nakai提取物的组合物。 包含抑制细胞衰老作为活性成分的极好效果的Synurus deltoides（Aiton）Nakai提取物的组合物可用于预防老年相关疾病如皮肤老化，类风湿性关节炎，骨关节炎，肝炎，慢性损伤 皮肤组织，动脉硬化，前列腺增生或肝癌。

公开(公告)号：KR101429209B1

公开(公告)日：2014-08-18

申请号：KR1020120151232

申请日：2012-12-21

Applicant: 대한민국(농촌진흥청장)

Inventor： 김영옥 ,  이상원 ,  노형준 ,  김승유 ,  유영복

IPC: A23L33/00 ,  A61K36/07 ,  A61P25/28

Abstract: 본 발명은 뇌기능 및 인지 기능 개선 활성을 갖는 조성물에 관한 것으로서, 보다 상세하게는 노루궁뎅이버섯, 노랑느타리버섯 및 세송이버섯으로 구성된 군에서 선택된 2종 이상의 버섯의 물 추출물을 유효성분으로 함유하는 뇌기능 및 인지 기능 개선용 조성물에 관한 것이다.

公开(公告)号：KR1020140082055A

公开(公告)日：2014-07-02

申请号：KR1020120151232

申请日：2012-12-21

Applicant: 대한민국(농촌진흥청장)

Inventor： 김영옥 ,  이상원 ,  노형준 ,  김승유 ,  유영복

IPC: A23L33/00 ,  A61K36/07 ,  A61P25/28

CPC classification number: A23L33/105 ,  A23V2002/00 ,  A23V2200/322 ,  A23V2250/21 ,  A61K36/07

Abstract: The present invention relates to a composition for improving brain function and cognitive function. In particular, the composition for improving brain function and cognitive function contains two or more mushroom extracts, selected from a group consisting of Hericium erinaceum, Pleurotus cornucopiae, and Pleurotus eryngii, as active ingredients.

Abstract translation: 本发明涉及一种用于改善脑功能和认知功能的组合物。 特别地，用于改善脑功能和认知功能的组合物含有两种或多种选自以下的蘑菇提取物：Hericium erinaceum，Pleurotus cornucopiae和Pleurotus eryngii作为活性成分。

公开(公告)号：KR1020140065661A

公开(公告)日：2014-05-30

申请号：KR1020120131218

申请日：2012-11-19

Applicant: 대한민국(농촌진흥청장)

Inventor： 김영옥 ,  이상원 ,  김승유 ,  신유수

IPC: A61K36/258 ,  A61K36/28 ,  A61K36/752 ,  A61P3/04

Abstract: The present invention relates to a composition for preventing and treating obesity and lipid-related metabolic diseases and a method for manufacturing the same. The composition of the present invention comprising powdered herbal components can suppress differentiation of adipocytes and generation of triglycerides, has excellent functionality, and has an effect of inhibiting obesity such as weight loss and blood lipid level reduction in obesity-induced animals by inhibiting differentiation of adipocytes, thereby being greatly helpful for preventing and treating obesity and lipid-related metabolic diseases.

Abstract translation: 本发明涉及用于预防和治疗肥胖症和与脂质有关的代谢疾病的组合物及其制造方法。 包含粉末草药成分的本发明的组合物可以抑制脂肪细胞的分化和甘油三酯的产生，具有优异的功能性，并且具有通过抑制脂肪细胞分化来抑制肥胖诱导的动物的肥胖，例如体重减轻和血脂水平降低的作用 从而对预防和治疗肥胖症和脂质代谢疾病有很大的帮助。

公开(公告)号：KR1020140053061A

公开(公告)日：2014-05-07

申请号：KR1020140034139

申请日：2014-03-24

Applicant: 대한민국(농촌진흥청장)

Inventor： 이승은 ,  이정훈 ,  최재훈 ,  노형준 ,  김금숙 ,  김승유 ,  홍윤표

IPC: A61K36/185 ,  A61P29/00

CPC classification number: A61K36/185 ,  A23L33/105 ,  A23V2002/00 ,  A23V2200/30 ,  A23V2250/21

Abstract: The present invention relates to a pharmaceutical composition and a health functional food containing an extract of Abutilon theophrasti Medicus leaf as an active component and, more specifically, to a pharmaceutical composition for preventing and treating an inflammatory disease characterized by an extract of Abutilon theophrasti Medicus leaf inhibiting the expression of an inflammatory protein in the body comprising one or more element among a group composed of cyclooxygenase-2 (COX-2), nitric oxide synthase (iNOS), and nuclear factor kappa B (NF-kB). The pharmaceutical composition and health functional food has anti-inflammation, anti-oxidation, and anti- arteriosclerosis activities.

Abstract translation: 本发明涉及药物组合物和含有作为活性成分的芸香属植物提取物的保健功能性食品，更具体地，涉及用于预防和治疗以Abutilon theophrasti Medicus leaf的提取物为特征的炎性疾病的药物组合物 包括由环氧合酶-2（COX-2），一氧化氮合酶（iNOS）和核因子κB（NF-kB）组成的组中的一种或多种元素的体内炎性蛋白的表达。 药物组合物和保健功能食品具有抗炎，抗氧化和抗动脉硬化的作用。

公开(公告)号：KR1020130084372A

公开(公告)日：2013-07-25

申请号：KR1020120005085

申请日：2012-01-17

Applicant: 대한민국(농촌진흥청장)

Inventor： 김금숙 ,  박춘근 ,  이승은 ,  노형준 ,  김영옥 ,  김승유 ,  김형돈 ,  홍윤표

IPC: A61K36/30 ,  A61P19/02 ,  A61P19/00

Abstract: PURPOSE: A composition containing a Lithospermum erythrorhizon Sieb. et Zucc. root extract is provided to significantly treat osteoarthritis and to be used as an agent for preventing and treating osteoarthritis or as a health food for treating osteoarthritis. CONSTITUTION: A therapeutic agent for treating osteoarthritis contains effective amount of natural pigments of Lithospermum erythrorhizon Sieb. et Zucc. roots. The natural pigment is a shikonin derivative, acetyl shikonin. An agent for preventing osteoarthritis contains effective amount of the natural pigments. A method for preparing a Lithospermum erythrorhizon Sieb. et Zucc. root extract for preventing and treating osteoarthritis comprises the steps of extracting Lithospermum erythrorhizon Sieb. et Zucc. roots with a non-polar solvent and obtaining the natural pigments. A method for preparing a Lithospermum erythrorhizon Sieb. et Zucc. root extract for preventing and treating osteoarthritis comprises the step of extracting the natural pigments by supercritical extraction. [Reference numerals] (G2) MIA + green-shelled mussel oil extract 150mg/kg; (G3) MIA + supercritical extract of Lithospermum erythrorhizon Sieb. et Zucc. 200mg/kg; (G4) MIA + acetylshikonin of Lithospermum erythrorhizon Sieb. et Zucc. 5mg/kg

Abstract translation: 目的：一种含有紫草紫草素的组合物。 等Zucc。 提供根提取物以显着治疗骨关节炎并且用作预防和治疗骨关节炎的药剂或用作治疗骨关节炎的保健食品。 构成：用于治疗骨关节炎的治疗剂含有有效量的紫苏紫苏的天然色素。 等Zucc。 根。 天然色素是紫草素衍生物，乙酰紫草素。 用于预防骨关节炎的药物含有有效量的天然色素。 一种制备紫苏红赤霉素的方法。 等Zucc。 用于预防和治疗骨关节炎的根提取物包括提取紫苏红赤霉素Sieb的步骤。 等Zucc。 根用非极性溶剂并获得天然颜料。 一种制备紫苏红赤霉素的方法。 等Zucc。 用于预防和治疗骨关节炎的根提取物包括通过超临界萃取提取天然色素的步骤。 [参考数字]（G2）MIA +绿壳贻贝油提取物150mg / kg; （G3）MIA +超临界提取物。 等Zucc。 200mg / kg的; （G4）MIA +紫草素的紫草素。 等Zucc。 为5mg / kg

公开(公告)号：KR101945865B1

公开(公告)日：2019-02-11

申请号：KR1020160114105

申请日：2016-09-05

Applicant: 대한민국(농촌진흥청장)

Inventor： 이승은 ,  김금숙 ,  노형준 ,  이정훈 ,  최재훈 ,  이대영 ,  김승유 ,  안영섭

IPC: A61K8/97 ,  A23L1/30 ,  A61K8/02 ,  A61K36/28 ,  A61Q19/08

公开(公告)号：KR101945864B1

公开(公告)日：2019-02-11

申请号：KR1020160114091

申请日：2016-09-05

Applicant: 대한민국(농촌진흥청장)

Inventor： 이승은 ,  김금숙 ,  노형준 ,  이정훈 ,  최재훈 ,  이대영 ,  김승유 ,  안영섭

IPC: A61K8/97 ,  A23L1/30 ,  A61K8/02 ,  A61K36/28 ,  A61Q19/08

公开(公告)号：KR101865148B1

公开(公告)日：2018-07-04

申请号：KR1020170121812

申请日：2017-09-21

Applicant: 대한민국(농촌진흥청장)

Inventor： 이승은 ,  이대영 ,  노형준 ,  이정훈 ,  김금숙 ,  김승유 ,  안영섭 ,  최재훈 ,  이재원

IPC: A61K36/62 ,  A23L33/105

Abstract: 본발명은연 자방및 연수술추출물을유효성분으로포함하는알레르기질환의예방또는치료용조성물에관한것으로, 더욱상세하게는베타-헥소사미니데이즈방출을억제하고, 염증성사이토카인및 IgE를억제하며, 리폭시게네이즈를저해함으로써염증질환또는알레르기질환의치료에효과적인조성물에관한것이다.

公开(公告)号：KR1020170027594A

公开(公告)日：2017-03-10

申请号：KR1020150124426

申请日：2015-09-02

Applicant: 대한민국(농촌진흥청장)

Inventor： 이승은 ,  김금숙 ,  노형준 ,  이정훈 ,  최재훈 ,  이대영 ,  김승유 ,  안영섭

IPC: A61K36/28 ,  A23L1/30

Abstract: 본발명은울릉국화추출물을유효성분으로포함하는염증성질환의예방또는치료용약학적조성물에관한것으로, 더욱자세하게는울릉국화추출물을유효성분으로포함하는염증성질환의예방또는치료용건강기능식품, 피부외용제또는화장료조성물에관한것이다. 본발명의울릉국화추출물은세포독성없이염증성질환을치료또는예방할수 있어효과적이다.