Abstract:
The present invention provides an adjustment technique of a medical image required to monitor diseases in the medical image obtained from a same patent at different times. According to the present invention, provided is a parallel processing method of a three-dimensional (3D) medical image adjustment using GP-GPU. The present invention is applied with parallel processing based on the GP-GPU in order to rapidly and accurately process 3D medical image data by gathering strengths of an existing division-based technique and a pixel-based technique. [Reference numerals] (AA) Input 2 volume; (BB) Scaling; (CC) Initialization step; (DD) Extract binary volume; (EE) Calculate the center; (FF) Calculate the principal axis of inertia; (GG) Optimization step; (HH) Convert floating volume; (II) Update P; (JJ) Is m_val minimum?; (KK) Optimize; (LL) Matched volume; (MM) P : Set of transformation parameters; (NN) m_val : Voxel similarity measurement value
Abstract:
The present invention relates to a stem cell source derived from a fetal cartilage tissue and a cellular therapeutic agent comprising the same. The present invention relates to a development of a stem cell source using fetal tissue derived cells, which have less restriction in ethics than the existing known embryonic stem cell, facilitate the control of differentiation, and have more excellent proliferative performance and differentiating performance than adult stem cells. According to the present invention, the cells isolated from the fetal cartilage tissue express a surface antigen specific to embryonic stem cells, such as SSEA-4, and a transcription factor specific to embryonic stem cells, such as Oct4, and also express surface antigens of mesenchymal stem cells, such as Stro-1, CD29, CD90, and CD105. The cells derived from the fetal cartilage tissue are more excellent in the cell proliferative performance and the differentiating performance into various cell tissues than adult stem cells, and thus can be used as a new stem cell source for regenerating damaged tissues. Particularly, the cells derived from the fetal cartilage tissue were verified to form no tumors when being transplanted under the skin of immunosuppressive mice (nude mice), and can be transplanted in the human body at high safety.
Abstract:
A method for preparing a biochip of cell stimulation and detection is provided to obtain the chip capable of applying mechanical stimulation to cells and also detecting and observing it at the same time with a single chip, thereby being used for stem cell, and applied to tissue engineering, medicals and pharmaceuticals. The method for fabricating a cell stimulation and detection bio-chip comprises the steps of: (a) applying a micro-machining process to a lower substrate made of silicone, glass or polymer to form a micro-channel, a stimulation chamber, and a detection chamber; (b) fabricating an inlet and an outlet of a fluid on an upper substrate using an electrochemical discharge machining process; (c) connecting the upper substrate to the lower substrate; and (d) attaching a driver for mechanical stimulation thereto.