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公开(公告)号：JPH10206214A
公开(公告)日：1998-08-07
申请号：JP1111797
申请日：1997-01-24
Applicant: ALOKA CO LTD
Inventor： TAKEDA MASAAKI , MATSUDA TORU
Abstract: PROBLEM TO BE SOLVED: To shorten a time for moving up and down a nozzle, by setting a plurality of light-measuring devices which detect transmission light quantity characteristics arranged in the longitudinal direction of the nozzle as partial characteristics in accordance with an up-down movement of the nozzle, coupling the obtained partial characteristics and forming a transmission light quantity characteristic of the whole nozzle. SOLUTION: A nozzle 8 is lowered by a driving mechanism 18 to suck and dispense a predetermined amount of a sample 7 in a sample container 6 into a nozzle chip 10. The nozzle 8 is then pulled up. A partial characteristic obtained by a first light- measuring unit 20 is temporarily stored in a first partial characteristic memory 32. Similarly, a partial characteristic obtained by a second light-measuring unit 22 is temporarily stored in a partial characteristic memory 34. A characteristic-coupling part 36 couples the partial characteristics stored in the memories 32, 34 thereby forming a transmission light quantity characteristic covering the whole of a characteristic detection range. The formed transmission light quantity characteristic is sent to an operating part 38, and stored in a memory part 40 if it is necessary. The operating part 38 compares two transmission light quantity characteristics before and after the sample 7 is sucked, thereby operating a suction amount.
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公开(公告)号：JPH09304399A
公开(公告)日：1997-11-28
申请号：JP12515596
申请日：1996-05-20
Applicant: ALOKA CO LTD
Inventor： TAKEDA MASAAKI , OSHIMA TOSHINORI , NIWAYAMA HIROAKI
Abstract: PROBLEM TO BE SOLVED: To enhance the dispensing process capability of an entire device by providing a exclusive dispensing section for an inspection item that is frequently dispensed. SOLUTION: A device main body is provided with first and second conveyor lines 12, 14 and first and second dispensing section 40, 42. The first dispensing section 40 has two dispensing nozzles and dispenses a single item at a high speed. The second dispensing section 42 has one dispensing nozzle and dispenses a number of items, while sorting them. A labeling part 62 performs a label issuing function, a label sticking function, and a label content confirming function. If an internal conveyor line 30 is selected by means of a discharge end switching part 26, a sample rack is lowered by an elevator mechanism 32 and fed into the internal conveyor line 30. The device also performs the function of re-arranging slave sample containers.
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公开(公告)号：JPH09264772A
公开(公告)日：1997-10-07
申请号：JP7492596
申请日：1996-03-28
Applicant: ALOKA CO LTD
Inventor： TAKEDA MASAAKI , MATSUDA TORU
Abstract: PROBLEM TO BE SOLVED: To accurately calculate a suction amount and discharge amount by directly monitoring liquid level in a nozzle. SOLUTION: A nozzle 10 has a nozzle base 12 and a nozzle tip 14. An ultrasonic sensor 18 is provided at the base 12. The liquid level of sample in liquid is detected by the sensor 18. Since the ultrasonic wave is transmitted and received in the nozzle 10, the convergence of the ultrasonic wave can be enhanced, and external noise can be shut off. The suction amount and, discharge amount can be calculated, liquid leakage can be discriminated and suction failure is discriminated based on the level detected result.
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公开(公告)号：JPH0979953A
公开(公告)日：1997-03-28
申请号：JP23540795
申请日：1995-09-13
Applicant: ALOKA CO LTD
Inventor： TAKEDA MASAAKI , MATSUDA TORU
Abstract: PROBLEM TO BE SOLVED: To collect blood samples of a fixed quantity by repeatedly performing pressure reduction and opening to the air on an airtight space formed below a container placed on the outlet side of a sample collecting needle and setting the pressure reducing time within a range in which the collected amount of blood becomes proportional to time from the suction starting time, and then, setting the opening time at the period until the internal pressure of the space returns to the atmospheric pressure after space is opened to the air. SOLUTION: When a blood-collecting tube 16 is inserted into a coupler 14 from the above and continuously pressed down, the coupler 12 tightly comes into contact with a sampling container 18 and an airtight space is formed below a blood-collecting needle. A suction pump 46 reduces the internal pressure of the space and an open valve 42 opens the space to the air. A control section 50 controls the pump 46 and valve 42 and is provided with a timer A which controls the pressure reducing time and the airtight space opening time and another timer B which controls the elapsed time from the sampling starting time. Therefore, samples of a fixed quantity are collected by repeating basic steps of pressure reduction and opening to the air on the space by setting the pressure reducing time within a range within which the collected amount of blood becomes proportional to the elapsed time from the suction starting time and the airtight space opening time to the period from the opening time to the time at which the internal pressure of the space returns to the atmospheric pressure.
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公开(公告)号：JPH08320318A
公开(公告)日：1996-12-03
申请号：JP12803795
申请日：1995-05-26
Applicant: ALOKA CO LTD
Inventor： TAKEDA MASAAKI , MATSUDA TORU
Abstract: PURPOSE: To obtain a sampling apparatus by which a blood sample in the interior of a blood sampling tube is sampled efficiently and safely without removing a sealing stopper from the blood sampling tube. CONSTITUTION: A coupler 12 is mounted on a coupler base 10, and a blood sampling tube 14 after a centrifugal separation treatment is inserted into the coupler 12 in an inverted state. Thereby, a blood sampling needle 26 is pierced through a rubber stopper 22. A packing 40 is used to seal a part between the coupler base 10 and a sampling container 24 and to seal a part between the coupler 12 and the coupler base 10. When the air in the interior of the sampling container 24 is sucked, an air passage 36 functions as a ventilation passage, and a serum 20 is taken into the sampling container 24 via a sample passage 34. While the interior of the blood sampling tube 14 is being maintained always under atmospheric pressure or lower, the serum 20 is sampled.
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Patent Agency Ranking
公开(公告)号：JPH0777527A
公开(公告)日：1995-03-20
申请号：JP22239793
申请日：1993-09-07
Applicant: ALOKA CO LTD
Inventor： MORI SHIGEMITSU , TAKEDA MASAAKI , KOJO YOSHIYUKI , MATSUDA TORU
Abstract: PURPOSE:To extract only the blood serum from a blood sampling tube containing blood after centrifugal separation by means of a single sampling needle. CONSTITUTION:A sampling needle 26 is set at the center of a blood sampling tube coupler 22 while piercing a rubber member 54 disposed at the center of a sealing plug 50. Pressure is increased and decreased repeatedly to a sampling container 14 thus sucking blood serum 18 therein through the sampling needle 22. A cleaning cap is employed for cleaning the blood sampling coupler 22.
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公开(公告)号：JPH0749351A
公开(公告)日：1995-02-21
申请号：JP19436193
申请日：1993-08-05
Applicant: ALOKA CO LTD
Inventor： TAKEDA MASAAKI
Abstract: PURPOSE:To provide a throwaway tip and dispenser for optically detecting the absolute position of the end of the throwaway tip and/or the engagement condition of the tip, in measuring liquid amount, for correctly sucking and discharging a sample. CONSTITUTION:The light, of a beam 20, transmitted through a tip 36 is detected by a photo detector 24, the level of the transmitted quantity of light from the end till the base engaged with a nozzle base, of a tip 36 not yet sucking, of a sample 12 is stored in a reference memory 82, and on the other hand the level of the transmitted quantity of light from the end till the base engaged with a nozzle base, of a tip 36 having put the sample 12, is stored in a transmitted light quantity level memory 80. Characteristic transmitted light quantity levels due to a mark 100 from outputs (a), (b) from both memories are respectively detected by a tip end detector 84, the transmitted light level at the same position longitudinal of the tip 36 is compared therewith on the basis of the mark 100, and the end position of the discharge opening of the tip 36 containing the sample 12 is detected.
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公开(公告)号：JPH0735759A
公开(公告)日：1995-02-07
申请号：JP17870093
申请日：1993-07-20
Applicant: ALOKA CO LTD
Inventor： TAKEDA MASAAKI , MATSUDA TORU
Abstract: PURPOSE:To provide a method for detecting a droplet wherein whether or not a droplet generated at the tip of a nozzle at dispensing time exists, and it dispenser. CONSTITUTION:A dispenser forms a light beam 20 by a near infrared light emitting diode 14, a lens 16 for converting the emitted near infrared light into a parallel light beam, and a cylindrical lens 18 for narrowing the parallel beam into a size in an axial direction of a chip 36, wherein the light beam 20 has an axis of the chip 36 and a beam width larger than a vertical width. Therefore if a droplet is generated from the tip of the chip 36, the droplet and the beam 20 cross each other. If a droplet detection circuit 26 receives a transmitted light amount at the time of movement of the chip 36 via an optical filter 22 at a light receiving part and a light detector 24 and senses a rapid change in the transmitted light amount level, it outputs a signal indicating 'generation of droplets' to a monitor 28 and issues a warning to a user by displaying a message indicating the generation of droplets.
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公开(公告)号：JPH06182234A
公开(公告)日：1994-07-05
申请号：JP34270792
申请日：1992-12-22
Applicant: ALOKA CO LTD
Inventor： TOKUNAGA NOBORU , TAKEDA MASAAKI
Abstract: PURPOSE:To provide the disposable tip for dispensing blood into another container with good accuracy in the state of hermetically closing a vacuum blood collecting tube in blood inspection. CONSTITUTION:This disposable tip 16 has >=1 vent paths 18 provided integrally with its side wall. These vent paths 18 have upper vent ports 19a provided at the top end of the disposable tip 16 fitting to a nozzle base and lower vent ports 19b provided in any part from the top end of the disposable tip 16 to a sample and suction port. The outdoor air is infiltrated into the vacuum blood collecting tube 28 through the vent paths 18 until the same pressure as the atm. pressure is attained simultaneously when the disposable tip 16 is inserted into the vacuum blood collecting tube 28 by provision of these vent paths 18. As a result, the sample is dispensed with the good accuracy by using a pump.
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公开(公告)号：JPH0325351A
公开(公告)日：1991-02-04
申请号：JP16179389
申请日：1989-06-23
Applicant: ALOKA CO LTD
Inventor： YOSHIMURA TOMOYUKI , OKABE TAKEYOSHI , KAWANABE JUNICHI , TAKEDA MASAAKI , ARAKI KOSUKE
Abstract: PURPOSE:To preclude an error dispensation quantity due to air bubble generation and to enable stable inspection by detecting transmitted light when light emitted by a light emitting body is emitted in a beam shape and made to cross a container containing a sample and deciding whether or not there is an air bubble. CONSTITUTION:The sample 12 is put in a chip (container) 10 which transmits near infrared light and moved by a chip moving means 36 at a constant speed as shown by an arrow. The near infrared light from an LED 14 is a beam 20 which has constant width and constant thickness so as to cross the chip 10 through optical systems 16 and 18. The beam 20 which is transmitted through the chip 10 passes through an optical fiber 22 which passes only light having wavelength in the near infrared range and reaches a photodetector 24. A differentiation circuit 26 and a signal processing circuit 28 inputs the detection signal of a detector 24 to find staircase variation in the quantity of the light transmitted through the chip 10, and the result is used to decide whether or not there is an air bubble. Consequently, when the air bubble is detected, analysis is quitted or dispensation is performed again to perform stable analysis and inspection.
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