PROCESS FOR THE PREPARATION OF 1-ARYLOXY-METHYLKETONES

    公开(公告)号:DE3260018D1

    公开(公告)日:1984-01-19

    申请号:DE3260018

    申请日:1982-01-07

    Applicant: BAYER AG

    Abstract: A process for the preparation of a 1-aryloxy-methyl ketone of the formula in which R1, R2 and R3 each independently is hydrogen, optionally substituted alkyl, alkenyl, alkynyl or optionally substituted aryl, or R1 and R2 together are an alkylene chain, R4 each independently is halogen, alkyl, alkoxy, optionally substituted aryl or nitro, and n is 0, 1, 2 or 3, comprising hydrolyzing a 1-halogeno-2-aryloxy-1-alkene of the formula in which Hal is chlorine or bromine, under acidic conditions at a temperature from about 20 DEG to 150 DEG C. until it is about 95 to 100% complete, adding a base, and then bringing the reaction to completion under weakly alkaline conditions at about 20 DEG to 150 DEG C. Advantageously all stages of the reaction are effected in a single vessel at a temperature from about 40 DEG to 100 DEG C. and in the presence of an inert organic solvent, optionally in admixture with water as a solution or as a two-phase system, about 1 mol of a monobasic acid and 2 mols of alkali metal carbonate being employed per mol of the 1-halogeno-2-aryloxy-1-alkene. The end products are known intermediates for fungicides.

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