公开(公告)号：CH594412A5

公开(公告)日：1978-01-13

申请号：CH222674

申请日：1974-02-18

Applicant: OREAL

Inventor： BOUILLON CLAUDE ,  VAYSSIE CHARLES ,  RICHARD FRANCOISE

IPC: A61K8/00 ,  A61K20060101 ,  A61K8/34 ,  A61K8/92 ,  A61K31/235 ,  A61L9/04 ,  A61Q17/04 ,  C07C20060101 ,  C07C49/613 ,  C07C49/743 ,  C07C67/00 ,  C07C301/00 ,  C07C303/06 ,  C07C303/08 ,  C07C303/32 ,  C07C309/25 ,  C07C309/28 ,  C07C309/44 ,  C07C309/58 ,  C07F3/06 ,  C09K3/30 ,  D06P1/41 ,  D06P3/04 ,  A61K7/42

Abstract: An anti-solar cosmetic composition contains as the anti-solar agent a compound of the formula wherein R represents a member selected from the group consisting of hydrogen, a halogen selected from the group consisting of chlorine and fluorine and alkyl containing 1-4 carbon atoms; R' and R'' each independently represent a member selected from the group consisting of hydrogen and SO3M wherein M represents a member selected from the group consisting of hydrogen, organic ammonium group and a metal, wherein at least one of R' and R'' is other than hydrogen, and R'' is a substituent at the para or meta position relative to the bornylidene ring. The anti-solar agent is present in amounts of 0.5-10 percent by weight of said composition.

公开(公告)号：CA994793A

公开(公告)日：1976-08-10

申请号：CA182366

申请日：1973-09-28

Applicant: OREAL

Inventor： BOUILLON CLAUDE ,  VAYSSIE CHARLES

IPC: A61K8/00 ,  A61K20060101 ,  A61K8/30 ,  A61K8/46 ,  A61K8/49 ,  A61K31/095 ,  A61K31/13 ,  A61K31/33 ,  A61K31/395 ,  A61K31/40 ,  A61K31/435 ,  A61K31/445 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/04 ,  A61Q5/10 ,  C07C20060101 ,  C07D20060101 ,  C07D295/08 ,  C11D3/28 ,  C11D3/30

Abstract: A method and composition for combatting the greasy and unaesthetic appearance of the hair and to improve the appearance of the skin comprises in a carrier at least one active component of the formula R1 R-S-CH2-CH-CH2-N ANGLE ¦ OHR2 wherein R1 and R2 are methyl, ethyl, isopropyl, cyclohexyl, benzyl or beta -hydroxyethyl, or R1 and R2 taken together form -(CH2)2-(CH2)2-, -(CH2)2-CH2-(CH2)2-, -(CH2)2-O-(CH2)2-, -(CH2)2-N-(CH2)2-, ¦ CH3 or -(CH2)2-N-(CH2)2-; ¦ C6H5 ; and R is (1) linear or branched alkyl having 1-18 carbon atoms, (ii) alkenyl having 3-18 carbon atoms, (iii) alkyl having 2-3 carbon atoms and substituted by 1-2 alcohol functions, (iv) -(CH2)m-CH(OR3)2 wherein R3 is alkyl having 1-4 carbon atoms and m is 1-2, (v) -(CH2)nR4 wherein n is 0, 1 or 2 and R4 is 2 -pyridyl or phenyl, (vi) -(CH2)qR'4 wherein q is 0 or 1 and R'4 is 1-naphthyl, 2-naphthyl WHEREIN P IS 1, 2 OR 3 IN WHICH INSTANCE R5 is F, Cl, Br, alkoxy having 1-5 carbon atoms or alkyl having 1-4 carbon atoms, or wherein p is 1 in which instance R5 is amino, dimethylamino and methylenedioxy, (vii) -CH(C6H5)2, (viii) -C(C6H5)3, (ix) -CH(C6H4p-OCH3)2, (x) -CH2-CH-NH2, ¦ COOH (xi) -CH2-CH2-NH-Y wherein Y is hydrogen, nicotinyl or COR9 wherein R9 is hydrogen, alkyl having 1-18 carbon atoms, alkenyl having 2-18 carbon atoms WHEREIN R11 is H, F, Cl, Br or alkoxy having 1-4 carbon atoms, (xii) -CH-COOH ¦ CH2-COOH, and (xiii) -(CH2)s-COOH wherein s is 1-10.

公开(公告)号：CA994671A

公开(公告)日：1976-08-10

申请号：CA151986

申请日：1972-09-18

Applicant: OREAL

Inventor： KALOPISSIS GREGOIRE ,  BOUILLON CLAUDE

IPC: A61K8/44 ,  A61K8/64 ,  A61K31/10 ,  A61K31/13 ,  A61K31/195 ,  A61Q5/00 ,  A61Q19/00 ,  C07D213/32 ,  C07D213/70 ,  C07K5/02 ,  C11D1/00

Abstract: A composition and method for treating the scalp and skin characterized by an excessive secretion of sebum, to improve the condition thereof and to reduce a greasy and unaesthetic appearance of the hair comprising topically applying to the scalp or skin or orally administering to a person having a scalp or skin so characterized, a composition containing effective amounts of S-substituted derivatives of glutathione as the active component in said composition.

公开(公告)号：DE2248240A1

公开(公告)日：1973-11-22

申请号：DE2248240

申请日：1972-10-02

Applicant: OREAL

Inventor： BOUILLON CLAUDE ,  ROSENBAUM GEORGES

IPC: C07D213/89 ,  C07F5/06 ,  C07D31/48

Abstract: An antiperspirant-deodorant composition containing in a cosmetic carrier an active compound of the formula WHEREIN X is chlorine, bromine and R1SO3 wherein R1 is alkyl of 1-4 carbon atoms, phenyl, chlorophenyl, hydroxyphenyl and 2-oxo 10-bornanyl and R is hydrogen, chlorine, methyl or methoxy.

公开(公告)号：DE2245903A1

公开(公告)日：1973-03-29

申请号：DE2245903

申请日：1972-09-19

Applicant: OREAL

Inventor： KALOPISSIS GREGOIRE ,  BOUILLON CLAUDE

IPC: A61K8/44 ,  A61K8/64 ,  A61K31/10 ,  A61K31/13 ,  A61K31/195 ,  A61Q5/00 ,  A61Q19/00 ,  C07D213/32 ,  C07D213/70 ,  C07K5/02 ,  C11D1/00 ,  C07C103/52

Abstract: A composition and method for treating the scalp and skin characterized by an excessive secretion of sebum, to improve the condition thereof and to reduce a greasy and unaesthetic appearance of the hair comprising topically applying to the scalp or skin or orally administering to a person having a scalp or skin so characterized, a composition containing effective amounts of S-substituted derivatives of glutathione as the active component in said composition.

公开(公告)号：GB1260227A

公开(公告)日：1972-01-12

申请号：GB1770569

申请日：1969-04-03

Applicant: OREAL

Inventor： KALOPISSIS GREGOIRE ,  BOUILLON CLAUDE

IPC: A61K20060101 ,  A61K8/46 ,  A61Q5/04 ,  A61Q9/04

Abstract: 1,260,227. Depilatory. L'OREAL. 3 April, 1969 [5 April, 1968], No. 17705/69. Heading A5B. [Also in Division Dl] A depilatory composition contains a sulphydryl reducing agent of the formula: where R represents either R 1 , R 2 , R 3 and R 4 represent H, OH, COOH, CH 2 OH or NH 3 and may be the same or different providing that (a) both R 1 and R 2 are not H or OH, or one H and the other OH, and (b) both R 3 and R 4 are not H. R 1 and R 2 together and R 3 and R 4 together may represent a divalent radical forming a cyclic structure which may contain a hetero atom. The composition contains 0.5-10% by weight of the agent, has a pH of 11-13, and is preferably in the form of a lotion, cream or gel. Example 3 relates to an aqueous cream containing 1, 4-dimercaptobutanediol-2, 3 (threo); calcium hydroxide; urea; and oxyethylenated alcohols (thickening agent).

公开(公告)号：DE2039408A1

公开(公告)日：1971-02-18

申请号：DE2039408

申请日：1970-08-07

Applicant: OREAL

Inventor： KALOPISSIS GREGOIRE ,  BOUILLON CLAUDE

IPC: A61K20060101 ,  A61K8/46 ,  A61K31/17 ,  A61Q5/02 ,  A61Q5/04 ,  A61Q5/10 ,  C11D1/00 ,  A61K7/06

Abstract: 1286919 Anti - seborrhoeic compositions L'OREAL 7 Aug 1970 [8 Aug 1969] 38276/70 Heading A5B [Also in Divisions C5 and Dl] Anti-seborrhoeic compositions comprise (a) a compound of formula: in which X is Cl or Br and n is 2 or 3 and (b) a carrier, the pH being 3-7 when compound I is present and 7-8 when compound II is present. Compounds specified are: #-aminoethyl isothiouronium chloride hydrochloride, #-aminoethyl isothiouronium bromide hydrobromide and γ-aminopropyl isothiouronium chloride hydrochloride. The carrier may be water or aqueous alcohol. The composition may also include a resin, colouring matter and/ or a perfume. It may be a hair setting or styling lotion, cream or gel. Ingredients specified in the Examples are: dimethylhydantoinformaldehyde resin, dimethyl-dilaurylammonium chloride, polyvinyl pyrrolidone, vinyl acetate-acrylic acid copolymer, 1-aminopropylamino-anthraquinone, picramic acid, 4-(N-γ- aminoproplamino)-1-(N'methylamino) anthraquinone, triethanolamine, perfume, ethanol and water.

公开(公告)号：DE1917433A1

公开(公告)日：1970-03-12

申请号：DE1917433

申请日：1969-04-03

Applicant: OREAL

Inventor： KALOPISSIS GREGOIRE ,  BOUILLON CLAUDE

IPC: A61K20060101 ,  A61K8/46 ,  A61Q5/04 ,  A61Q9/04

公开(公告)号：FR2555898B1

公开(公告)日：1986-08-08

申请号：FR8418162

申请日：1984-11-29

Applicant: OREAL

Inventor： BOUILLON CLAUDE ,  LANG GERARD ,  LAUGIER JEAN-PIERRE

IPC: A61K31/415 ,  A61K8/00 ,  A61K8/25 ,  A61K8/29 ,  A61K8/30 ,  A61K8/33 ,  A61K8/35 ,  A61K8/36 ,  A61K8/368 ,  A61K8/37 ,  A61K8/38 ,  A61K8/41 ,  A61K8/44 ,  A61K8/46 ,  A61K8/49 ,  A61K8/73 ,  A61K31/12 ,  A61K31/185 ,  A61K31/19 ,  A61K31/215 ,  A61K31/245 ,  A61K31/255 ,  A61K31/60 ,  A61K33/40 ,  A61P17/00 ,  A61Q17/04 ,  A61Q19/00 ,  C07C67/00 ,  C07C407/00 ,  A61K31/235 ,  A61K7/42

Abstract: There is disclosed a composition for the local treatment of acne containing from 0.5 to 20% by weight of benzoyl peroxide in association with at least one sun filter that is benzylidenecamphor and its derivatives, 2-phenylbenzimidazole-5-sulfonic acid and its salts, 2-hydroxybenzenophenone and its derivatives, C2-C12 alkyl p-dimethylaminobenzoates, salicylic acid esters, dibenzoylmethane derivatives and cinnamic acid derivatives.

公开(公告)号：CA1204756A

公开(公告)日：1986-05-20

申请号：CA307605

申请日：1978-07-18

Applicant: OREAL

Inventor： BOUILLON CLAUDE ,  ROSENBAUM GEORGES

IPC: C07D215/36 ,  A61K8/00 ,  A61K8/26 ,  A61K8/58 ,  A61K31/44 ,  A61K31/4402 ,  A61K31/4406 ,  A61P31/04 ,  A61Q15/00 ,  A61Q19/00 ,  C07C67/00 ,  C07C301/00 ,  C07C303/22 ,  C07C303/32 ,  C07C309/19 ,  C07C309/24 ,  C07C309/29 ,  C07C309/39 ,  C07C309/42 ,  C07D213/71 ,  C07D213/89 ,  C07D215/24 ,  C07D215/28 ,  C07F5/06

Abstract: Les composés ayant la formule générale suivante : (I) dans laquelle : R1 représente un radical choisi dans le groupe constitué par : (i) un radical de formule : dans laquelle R' représente un radical méthyle, (ii) un radical de formule : (iii) un radical de formule : (iv) un radical de formule : (v) un radical de formule : (vi) un radical de formule : dans laquelle R" représente un atome d'hydrogène ou un radical iodo, (vii) un radical - CH2 - CH2 - NH2 et (viii) un radical - CH2 - - NH2 sont obtenu en préparant dans un premier temps un composé intermédiare de formule ; en faisant réagir en quantité équimoléculaire de l'isopropylate d'aluminium avec un acide sulfonique de formule R1SO3H dans laquelle R1 à la signification précitée et, dans un deuxième temps, en faisant réagir ce composé intermédiaire avec deux équivalents de N-oxyde de pyridine-2 thiol. Ces composés trouvent une application en cosmétique pour la réalisation de compositions désodorantes, antiperspirantes et anti-pellicu-laires ainsi que pour l'hygiène féminine.