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    REDUCING GASTROINTESTINAL IRRITATION IN INFANT NUTRITION
    41.
    发明申请
    REDUCING GASTROINTESTINAL IRRITATION IN INFANT NUTRITION 审中-公开
    减少哺乳动物胃肠道刺激

    公开(公告)号：WO1993020717A2

    公开(公告)日：1993-10-28

    申请号：PCT/US1993002915

    申请日：1993-03-29

    Applicant: RESEARCH CORPORATION TECHNOLOGIES, INC.

    Inventor： RESEARCH CORPORATION TECHNOLOGIES, INC. ,  CRISSINGER, Karen, D. ,  TSO, Patrick

    IPC: A23L01/29

    CPC classification number: A23L33/12 ,  A23L33/40 ,  Y10S426/801

    Abstract: Food products for nutrition of infants which contain no more than subirritant amounts of free long-chain (C16-C22) fatty acids and triglycerides thereof are disclosed. Providing esters, such as ethyl esters, of such fatty acids in infant food products essentially eliminates the tendency of the fatty acid to damage the infant intestinal epithelium, but permits absorption and processing of the fatty acid moiety.

    Abstract translation: 公开了含有不超过刺激剂量的游离长链（C16-C22）脂肪酸及其甘油三酯的婴幼儿营养食品。 在婴儿食品中提供这种脂肪酸的酯类如乙酯基本上消除了脂肪酸破坏婴儿肠上皮的倾向，但允许脂肪酸部分的吸收和加工。

    THE SONOCHEMICAL SYNTHESIS OF AMORPHOUS METALS
    44.
    发明申请
    THE SONOCHEMICAL SYNTHESIS OF AMORPHOUS METALS 审中-公开
    非晶金属的化学合成

    公开(公告)号：WO1993005877A1

    公开(公告)日：1993-04-01

    申请号：PCT/US1992008133

    申请日：1992-09-25

    Applicant: RESEARCH CORPORATION TECHNOLOGIES, INC.

    Inventor： RESEARCH CORPORATION TECHNOLOGIES, INC. ,  SUSLICK, Kenneth, S. ,  GRINSTAFF, Mark, E. ,  CICHOWLAS, Andrzej, A. ,  CHOE, Seok-Burm

    IPC: B01J35/00

    CPC classification number: B01J37/343 ,  B01J37/086 ,  B22F9/002 ,  B22F9/24 ,  H01F1/15341

    Abstract: The present invention relates to novel substantially pure amorphous metals and the sonochemical synthesis thereof comprising irradiating volatile organometallic compounds with high intensity ultrasound. The present invention is further directed to the use of amorphous metals as reactive catalysts for various processes such as the Fischer-Tropsch hydrogenation of carbon monoxide and for the hydrogenolysis and dehydrogenation of saturated hydrocarbons. The present invention further relates to the use of these amorphous metals as soft ferromagnetic materials.

    Abstract translation: 本发明涉及新颖的基本上纯的无定形金属及其声化学合成，其包括用高强度超声波照射挥发性有机金属化合物。 本发明还涉及无定形金属作为反应催化剂用于各种方法的用途，例如一氧化碳的费 - 托氢化和饱和烃的氢解和脱氢。 本发明还涉及这些非晶态金属作为软铁磁材料的用途。

    THE GENE ENCODING EQUINE HERPESVIRUS TYPE 1 GLYCOPROTEIN D, ITS GENE PRODUCT, ANTIBODIES AND THEIR USES
    47.
    发明申请
    THE GENE ENCODING EQUINE HERPESVIRUS TYPE 1 GLYCOPROTEIN D, ITS GENE PRODUCT, ANTIBODIES AND THEIR USES 审中-公开
    基因编码方法HERPESVIRUS TYPE 1 GLYCOPROTEIN D，其基因产物，抗体及其用途

    公开(公告)号：WO1992002252A1

    公开(公告)日：1992-02-20

    申请号：PCT/US1991005284

    申请日：1991-07-25

    Applicant: RESEARCH CORPORATION TECHNOLOGIES, INC.

    Inventor： RESEARCH CORPORATION TECHNOLOGIES, INC. ,  O'CALLAGHAN, Dennis, J.

    IPC: A61K39/42

    CPC classification number: C07K14/005 ,  A61K39/00 ,  C07K16/087 ,  C12N15/86 ,  C12N2710/14143 ,  C12N2710/16722

    Abstract: The present invention is directed to a gene encoding an envelope glycoprotein of equine herpesvirus type 1 (EHV-1), the glycoprotein D (gD) gene, its gene product and antibodies directed against gD polypeptides. The envelope glycoproteins of herpesvirus are major targets of the immune response to herpesviral infection. Hence, an important aspect of this invention is directed towards a vaccine against EHV-1 and treatment of EHV-1 infection by anti-EHV-gD antibodies or antisera.

    Abstract translation: 本发明涉及编码马疱疹病毒1型（EHV-1），糖蛋白D（gD）基因，其基因产物和针对gD多肽的抗体的包膜糖蛋白的基因。 疱疹病毒的包膜糖蛋白是对疱疹病毒感染的免疫应答的主要靶标。 因此，本发明的一个重要方面针对抗EHV-1疫苗和用抗EHV-gD抗体或抗血清治疗EHV-1感染的疫苗。

    1,2-DIHYDRO-3H-DIBENZISOQUINOLINE-1,3-DIONE ANTICANCER AGENTS
    48.
    发明申请
    1,2-DIHYDRO-3H-DIBENZISOQUINOLINE-1,3-DIONE ANTICANCER AGENTS 审中-公开
    1,2-二氢-3H-二苯并喹啉-1,3-二酮类抗生素

    公开(公告)号：WO1992000281A1

    公开(公告)日：1992-01-09

    申请号：PCT/US1991004364

    申请日：1991-06-19

    Applicant: RESEARCH CORPORATION TECHNOLOGIES, INC.

    Inventor： RESEARCH CORPORATION TECHNOLOGIES, INC. ,  ALBERTS, David, S. ,  DORR, Robert, T. ,  REMERS, William, A. ,  SAMI, Salah, M.

    IPC: C07D221/18

    CPC classification number: C07D401/04 ,  C07D221/18 ,  C07D401/06

    Abstract: This invention relates to a compound useful for the treatment of tumors having formula (I), wherein R8, R6 and R10 are independently hydrogen, lower alkyl, aryl, lower alkanoyl, formyl, halogen, nitro, NR2R3, OR1, or SR1, methoxy, hydroxy, cyano CO2H, SO2NR1R2, or CONR1R2; R1, R2 and R3 are independently hydrogen, lower alkyl, aryl lower alkyl, aryl, formyl or lower alkanoyl; R9, R11, R10 and R7 are independently hydrogen, or lower alkyl or R9 and R11 taken together with the carbon atoms to which they are attached form a phenyl group or R9 and R10 taken together with the carbon atoms to which they are attached form a phenyl group or R7 and R10 taken together with the carbon atoms to which they are attached from a phenyl group; A is (CR4R5)n3, lower cycloalkyl or aryl or a chemical bond; each R4 and R5 are independently hydrogen or lower alkyl; R12 and R13 are independently hydrogen, or lower alkyl which is unsubstituted or substituted with hydroxy, mercapto, lower alkoxy, lower alkylcarbonyloxy, carboxy, or carbloweralkoxy or R12 and R13 taken together with the nitrogen to which they are attached form a 3-6-membered heterocyclic ring; D is a chemical bond or taken together with NR12 form a 5 or 6-membered heterocyclic ring; n1 and n2 are independently 0, 1 or 2; and n3 is 0, 1, 2, 3, 4 or 5.

    Abstract translation: 本发明涉及可用于治疗具有式（I）的肿瘤的化合物，其中R 8，R 6和R 10独立地是氢，低级烷基，芳基，低级烷酰基，甲酰基，卤素，硝基，NR 2 R 3，OR 1或SR 1，甲氧基 ，羟基，氰基CO 2 H，SO 2 NR 1 R 2或CONR 1 R 2; R1，R2和R3独立地是氢，低级烷基，芳基低级烷基，芳基，甲酰基或低级烷酰基; R9，R11，R10和R7独立地为氢，或低级烷基或R9和R11与它们所连接的碳原子一起形成苯基或R 9和R 10与它们所连接的碳原子一起形成 苯基或R 7和R 10与它们所连接的碳原子一起与苯基一起; A是（CR4R5）n3，低级环烷基或芳基或化学键; 每个R 4和R 5独立地是氢或低级烷基; R 12和R 13独立地为氢，或未被取代或被羟基，巯基，低级烷氧基，低级烷基羰基氧基，羧基或碳氟烷基氧基取代的低级烷基，或者与它们所连接的氮一起形成的R 12和R 13一起形成3-6元环， 元环杂环; D是化学键或与NR12一起形成5或6元杂环; n1和n2独立地为0,1或2; n3为0,1,2,3,4或5。

    COATED PARTICLES AND METHODS OF COATING PARTICLES
    50.
    发明申请
    COATED PARTICLES AND METHODS OF COATING PARTICLES 审中-公开
    涂层颗粒和涂料颗粒的方法

    公开(公告)号：WO1991006036A1

    公开(公告)日：1991-05-02

    申请号：PCT/US1990006009

    申请日：1990-10-18

    Applicant: RESEARCH CORPORATION TECHNOLOGIES, INC.

    Inventor： RESEARCH CORPORATION TECHNOLOGIES, INC. ,  PATEL, Ramesh, C. ,  HILL, Steven, C.

    IPC: G03C01/00

    CPC classification number: G03C1/005

    Abstract: Methods of coating nanoparticles (30) with one or more layers of various types of materials such as metals (30b), polymers (30c) and halides (30d), and nanoparticles formed by those methods. A first embodiment of the invention is a method of forming silver halide (12b) coated dielectric nanoparticles (12a), and a second embodiment is a method of forming metal (14b) coated dielectric nanoparticles (14a). A first nanoparticle according to this invention comprises a dielectric nano-core and a silver halide coating; and a second nanoparticle comprises a dielectric nano-core, a metal shell over that core and a silver halide (14c) coating over the metal shell. A further nanoparticle of this invention comprises a dielectric nano-core (16a), a silver halide shell (16b) over the core and a metal shell (16c) over the silver halide; and a still further nanoparticle comprises a dielectric core (20a), a first shell of a first metal (20b) and a second shell (20c) of a second metal.

    Abstract translation: 用一种或多种各种类型的材料（例如金属（30b），聚合物（30c）和卤化物（30d））涂覆纳米颗粒（30）的方法和由这些方法形成的纳米颗粒。 本发明的第一个实施方案是形成涂覆有卤化银（12b）的介电纳米颗粒（12a）的方法，第二实施方案是形成金属（14b）涂覆的电介质纳米颗粒（14a）的方法。 根据本发明的第一纳米颗粒包括电介质纳米芯和卤化银涂层; 并且第二纳米颗粒包括电介质纳米芯，在该芯上的金属壳和金属壳上的卤化银（14c）。 本发明的另一种纳米颗粒包括电介质纳米芯（16a），核心上的卤化银外壳（16b）和卤化银上的金属外壳（16c）; 并且另外的纳米颗粒包括电介质芯（20a），第一金属（20b）的第一壳和第二金属的第二壳（20c）。

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