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1.发明申请SEPARATION OF ENANTIOMERS OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND CHIRAL SELECTOR THEREFOR 审中-公开非甾体抗炎药物及其选择器的成分的分离
公开(公告)号：WO1993006080A1
公开(公告)日：1993-04-01
申请号：PCT/US1992008006
申请日：1992-09-21
Applicant: RESEARCH CORPORATION TECHNOLOGIES, INC.
Inventor： RESEARCH CORPORATION TECHNOLOGIES, INC. , PIRKLE, William, H. , WELCH, Christopher, J. , LAMM, Bo, Robert
IPC: C07C233/65
CPC classification number: C07D307/00 , C07B57/00 , C07C51/487 , C07C233/65 , C07C2603/26 , C07D307/92
Abstract: The invention relates to a chiral selector useful in separating underivatized enantiomers of non-steroidal anti-inflammatory agents, particularly naproxen and other arylacetic acid compounds, and relates to a process for achieving such separation utilizing the chiral selector, which is also useful in achieving the enantiomeric separation of amines, alcohol derivatives, epoxides and sulfoxides. The invention is also directed to an apparatus which comprises the chiral selectors.
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2.发明申请FACE-TO-FACE/FACE-TO-EDGE INTERACTIVE CHIRAL SELECTORS AND RELATED APPARATUSES 审中-公开面对面/面对面交互式手机选择器及相关设备
公开(公告)号：WO1996039377A1
公开(公告)日：1996-12-12
申请号：PCT/US1996008626
申请日：1996-06-04
Applicant: RESEARCH CORPORATION TECHNOLOGIES, INC.
Inventor： RESEARCH CORPORATION TECHNOLOGIES, INC. , PIRKLE, William, H. , WELCH, Christopher, J. , LAMM, Bo, Robert
IPC: C07C275/30
CPC classification number: C07C51/487 , C07C275/30
Abstract: The invention relates to a chiral selector useful in separating underivatized enantiomers of nonsteroidal anti-inflammatory agents, particularly naproxen and other arylacetic acid compounds, and relates to a process for achieving such separation utilizing the chiral selector, which is also useful in achieving the enantiomeric separation of amines, alcohol derivatives, epoxides and sulfoxides. The invention is also directed to an apparatus which comprises the chiral selectors.
Abstract translation: 本发明涉及可用于分离非甾体抗炎剂，特别是萘普生和其它芳基乙酸化合物的未衍生化对映异构体的手性选择剂，涉及使用手性选择剂实现这种分离的方法，其也可用于实现对映体分离 的胺，醇衍生物，环氧化物和亚砜。 本发明还涉及一种包括手性选择器的装置。
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3.发明公开FACE-TO-FACE/FACE-TO-EDGE INTERACTIVE CHIRAL SELECTORS AND RELATED APPARATUSES 失效面对面/面对面交互式手动选择器及相关设备
公开(公告)号：EP0830340A1
公开(公告)日：1998-03-25
申请号：EP96917087.0
申请日：1996-06-04
Applicant: Research Corporation Technologies, Inc
Inventor： PIRKLE, William, H. , WELCH, Christopher, J. , LAMM, Bo, Robert
CPC classification number: C07C51/487 , C07C275/30
Abstract: The invention relates to a chiral selector useful in separating underivatized enantiomers of nonsteroidal anti-inflammatory agents, particularly naproxen and other arylacetic acid compounds, and relates to a process for achieving such separation utilizing the chiral selector, which is also useful in achieving the enantiomeric separation of amines, alcohol derivatives, epoxides and sulfoxides. The invention is also directed to an apparatus which comprises the chiral selectors.
Abstract translation: 本发明涉及用于分离非甾体抗炎药特别是萘普生和其他芳基乙酸化合物的未衍生对映体的手性选择剂，并且涉及利用手性选择剂实现这种分离的方法，其也用于实现对映体分离 胺，醇衍生物，环氧化物和亚砜。 本发明还涉及一种包括手性选择器的设备。
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