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    Pulmonary aerosol delivery device and method
    42.
    发明申请
    Pulmonary aerosol delivery device and method 失效

    公开(公告)号：US20020153006A1

    公开(公告)日：2002-10-24

    申请号：US10161545

    申请日：2002-06-03

    Inventor： William C. Zimlich JR. ,  James E. Dvorsky ,  David R. Busick ,  Richard D. Peters

    IPC: A61M011/00 ,  B05B017/06 ,  B05B007/00

    CPC classification number: B05B5/002 ,  A61M11/007 ,  A61M15/0065 ,  A61M15/008 ,  A61M15/0081 ,  A61M15/0083 ,  A61M15/025 ,  B05B5/0255 ,  B05B5/1691

    Abstract: A device and method for delivering an aerosolized liquid having therapeutic properties to a user's lungs. The compact and convenient device includes a housing of such size that it can be held in a user's one hand with an exit opening in the housing for directing the aerosol to the user's mouth. The housing encloses a dispensing system for containing the liquid to be aerosolized and delivering it to an electrohydrodynamic apparatus and an electrohydrodynamic apparatus for aerosolizing the liquid and delivering the aerosol to the exit opening. The electrohydrodynamic apparatus produces a cloud of aerosolized liquid droplets having a monodispersed respirable droplet size and near zero velocity. The aerosolizing apparatus includes a plurality of spray sites each having a tip end, the spray sites cooperating with a charge source to result in an aerosolized spray from at least one tip end, a plurality of discharge electrodes downstream of the tip ends, and a plurality of reference electrodes downstream of the plurality of discharge electrodes.

    Dispensing device
    43.
    发明授权
    Dispensing device 失效
    点胶装置

    公开(公告)号：US06386195B1

    公开(公告)日：2002-05-14

    申请号：US09377085

    申请日：1999-08-19

    Applicant: Ronald Alan Coffee

    Inventor： Ronald Alan Coffee

    IPC: A61M1100

    CPC classification number: B05B5/002 ,  A61M15/0091 ,  A61M15/0093 ,  A61M15/02 ,  B05B5/0255 ,  B05B5/043

    Abstract: A dispensing device has a liquid supplier having a liquid outlet; an electrical charger for generating an electrical field to cause liquid issuing from the liquid outlet to be comminuted to provide electrically charged comminuted matter; an electrical discharger for providing ions for at least partially electrically discharging the comminuted matter; and an ion attracter for attracting ions generated by the electrical discharger away from the electrical charger until a spray cloud of electrically charged comminuted matter has been established by the electrical charger.

    Abstract translation: 分配装置具有液体供应器，其具有液体出口; 用于产生电场以使液体从液体出口发出的液体被粉碎以提供带电粉碎物质的电动充电器; 放电器，用于提供用于至少部分电解排出粉碎物质的离子; 以及用于将由放电器产生的离子吸引离开充电器的离子吸收剂，直到充电器已经建立了充满电的粉碎物质的喷雾。

    Process and apparatus for spraying liquid
    45.
    发明授权
    Process and apparatus for spraying liquid 失效
    用于喷涂液体的方法和装置

    公开(公告)号：US4962885A

    公开(公告)日：1990-10-16

    申请号：US425431

    申请日：1989-10-24

    Applicant: Ronald A. Coffee

    Inventor： Ronald A. Coffee

    IPC: B05D1/04 ,  B05B5/00 ,  B05B5/025 ,  B05B5/053 ,  B05B5/16

    CPC classification number: B05B5/002 ,  B05B5/0255 ,  B05B5/0533 ,  B05B5/1691

    Abstract: A process and apparatus for spraying liquid at a target, which comprises atomizing liquid by charging it electrostatically, projecting the charge atomized liquid on a path toward the target and at least partially discharging the charged particles so formed with an ionic discharge induced by the particles as they pass an earthed electrode having a sharp or pointed edge sited adjacent said path.

    Abstract translation: 一种用于在目标上喷射液体的方法和装置，其包括通过静电充电来雾化液体，将电荷雾化液体投射到朝向目标的路径上，并且至少部分地将由粒子引起的离子放电形成的带电粒子排出， 它们通过具有邻近所述路径的锋利或尖锐边缘的接地电极。

    Apparatus and process for producing powders and other granular materials
    46.
    发明授权
    Apparatus and process for producing powders and other granular materials 失效
    用于生产粉末和其他颗粒材料的设备和方法

    公开(公告)号：US4788016A

    公开(公告)日：1988-11-29

    申请号：US62653

    申请日：1987-06-16

    Applicant: Michael L. Colclough ,  Timothy J. Noakes

    Inventor： Michael L. Colclough ,  Timothy J. Noakes

    IPC: C08J3/12 ,  B01J2/04 ,  B05B5/00 ,  B05B5/025 ,  B05B5/08 ,  B29B9/10 ,  B29B9/00 ,  B05B5/02

    CPC classification number: B05B5/002 ,  B01J2/04 ,  B05B5/0255 ,  B05B5/087

    Abstract: Electrostatic spraying apparatus and process for spraying liquids which form a coalescent resistant surface in flight in a particular environment to produce a powder or granular material. The process involves delivering a liquid to a spraying site of an electrostatic spray head; making contact with the liquid via an electrically conducting or semiconducting liquid contacting surface; charging the liquid contacting surface to a high voltage of one polarity relative to a reference surface to intensify the electric field strength at the spraying site sufficiently that the liquid at the spraying site is drawn out preponderantly by electrostatic forces into at least one cone from which a corresponding ligament issues and breaks up into a spray of electrostatically charged droplets; providing the environment in a space sufficient that droplets from the spray head form, in flight, particles having a substantially coalescent resistant surface; and collecting the particles so formed.

    Abstract translation: 静电喷涂装置和喷雾液体的方法，其在特定环境中在飞行中形成聚结剂表面以产生粉末或颗粒材料。 该方法包括将液体输送到静电喷头的喷涂部位; 通过导电或半导体液体接触表面与液体接触; 将液体接触表面充电到相对于参考表面的一个极性的高电压，以增强喷涂位置处的电场强度，足以使喷雾位置处的液体被静电力主要地抽出到至少一个锥体中， 相应的韧带问题并分解成静电带电液滴喷雾; 在足够的空间中提供环境，使得来自喷雾头的液滴在飞行中形成具有基本上聚结的表面的颗粒; 并收集如此形成的颗粒。

    METHODS OF ELECTROSPRAYING PARTICLES
    47.
    发明申请
    METHODS OF ELECTROSPRAYING PARTICLES 审中-公开
    电沉积颗粒的方法

    公开(公告)号：WO2016105982A1

    公开(公告)日：2016-06-30

    申请号：PCT/US2015/065394

    申请日：2015-12-11

    Applicant: NANOCOPOEIA, LLC

    Inventor： LASCH, James, E. ,  FU, Huijing ,  GOODE, Andrew ,  WYMAN, Joseph ,  RAHI, Mourad, F. ,  THAO, Doua ,  POPA, Mihnea

    IPC: B05B5/00 ,  B05B5/025 ,  B01J13/04

    CPC classification number: B05D1/06 ,  B05B5/001 ,  B05B5/002 ,  B05B5/0255

    Abstract: Methods of electrospraying particles are disclosed that include electrospraying a liquid spray composition from the nozzle (18), the liquid spray composition including a liquid and a compound that exhibits a melting point and a crystallization temperature, and at least one of exposing particles formed from the liquid spray composition to a temperature modified environment, exposing particles formed from the liquid spray composition to an organic solvent, and collecting particles formed from the liquid spray composition on at least one of a temperature modified collector (12), a liquid collector, a variable topography collector, and a dry ice collector.

    Abstract translation: 公开了电喷雾颗粒的方法，其包括从喷嘴（18）电喷雾液体喷雾组合物，液体喷雾组合物包括液体和显示熔点和结晶温度的化合物，以及至少一种由 将液体喷雾组合物喷射到温度改变的环境中，将由液体喷雾组合物形成的颗粒暴露于有机溶剂，以及将由液体喷雾组合物形成的颗粒收集在温度改变的收集器（12），液体收集器，变量 地形收集器和干冰收集器。

    INHALATION APPARATUS
    49.
    发明申请
    INHALATION APPARATUS 审中-公开
    吸入装置

    公开(公告)号：WO1994019042A1

    公开(公告)日：1994-09-01

    申请号：PCT/GB1994000338

    申请日：1994-02-21

    Applicant: BESPAK PLC ,  BALACHANDRAN, Wamadeva ,  AHMAD, Chaudhry, Nasir ,  BARNES, Paul,

    Inventor： BESPAK PLC

    IPC: A61M15/02

    CPC classification number: B05B5/002 ,  A61M15/0065 ,  A61M15/009 ,  A61M15/02 ,  A61M2016/0021 ,  A61M2202/064 ,  B05B5/0533

    Abstract: A housing defines a passageway having a mouth piece at one end and through which air is inhalable through the passageway, a dispenser being connected to the housing and operable to dispense a metered dose of aerosol liquid or powder. Electrodes (16, 22) are located intermediate the dispenser and the mouth piece and define a charging region (26). A charging circuit (21) applies a voltage across the electrodes, one of which has a pointed feature, such that particles passing through the charging region acquire charge of a predetermined polarity. A breath sensor (51) is used to co-ordinate operation of the charging circuit with the inhalation of the dose. The site of deposition of inhaled particles within the respiratory tract can thereby be influenced by selecting the magnitude and polarity of the voltage applied to the electrodes.

    Abstract translation: 壳体限定了在一端具有口部件的通道，空气通过该通道可吸入，分配器连接到壳体并且可操作地分配计量剂量的气溶胶液体或粉末。 电极（16,22）位于分配器和口部件之间并限定充电区域（26）。 充电电路（21）在电极之间施加电压，其中之一具有尖锐特征，使得通过充电区域的颗粒获得预定极性的电荷。 呼吸传感器（51）用于协调充电电路的操作与剂量的吸入。 因此，可以通过选择施加到电极的电压的大小和极性来影响吸入颗粒在呼吸道内的沉积位置。

    고분자 스프레이 침착 장치용 스프레이 충전 및 방전 시스템
    50.
    发明公开
    고분자 스프레이 침착 장치용 스프레이 충전 및 방전 시스템 审中-实审
    用于聚合物喷雾沉积装置的喷雾充电和放电系统

    公开(公告)号：KR1020160073911A

    公开(公告)日：2016-06-27

    申请号：KR1020150172926

    申请日：2015-12-07

    Applicant: 팔로 알토 리서치 센터 인코포레이티드

    Inventor： 존스티븐파스치케위츠 ,  에릭슈래더 ,  빅터벡

    IPC: B05B5/00 ,  B05B5/053 ,  B05B5/03 ,  B05B5/08 ,  B05D1/02

    CPC classification number: B29C64/112 ,  B05B5/002 ,  B05B5/04 ,  B05B17/04 ,  B05D1/04 ,  B33Y30/00 ,  B33Y50/02 ,  B41J2/04526 ,  B41J2/04586

    Abstract: 개시되는스프레이침착시스템들및 방법들은스프레이충전및 방전기술들을사용하여기판상에스프레이액적들의디지털침착을지원한다. 예를들어개시되는시스템들및 방법들은스프레이발생기로부터스프레이액적들을생성하고또한그 액적들을충전하는충전시스템을갖는다. 집속전극들은액적들을조밀한액적스트림내로시준하도록협조하고또한선택적으로조향전극들은조밀한액적스트림을지향하도록협조한다. 전하제거시스템은기판상의액적들을침착하는동안또는액적들이기판상에침착된후 액적들로부터전하를중화또는제거한다.

    Abstract translation: 喷雾沉积系统和方法通过使用喷雾充放电技术支持液滴在基底上的数字沉积。 例如，系统和方法从喷雾发生器产生喷雾液滴，还具有用于对液滴进行充电的充电系统。 聚焦电极彼此配合以将液滴准直成致密的液体流并且彼此配合以允许转向电极选择性地面对致密的液体流。 电荷去除系统在将液滴沉积在基底上或同时将液滴沉积在基底上时，中和或从液滴中去除电荷。

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