公开(公告)号：WO2018106947A1

公开(公告)日：2018-06-14

申请号：PCT/US2017/065159

申请日：2017-12-07

Applicant: STC. UNM

Inventor： HAN, Sang, M. ,  CALDWELL, Jarred ,  BRECHTEL, Nicholas ,  MADRID, Nathan ,  PRAKASH, Divya

IPC: A61B5/06 ,  A61B5/05 ,  A61M25/095

Abstract: An apparatus tor determining a position of an object inside a body includes a first, detector configured to receive a signal from the object inside the body. The apparatus also includes a camera configured to capture m image or video of outside of a portion of the body, The object is positioned inside the portion of the body. A connoting system is configured to receive the signal from the first detector and the image or video from the camera and to determine the position of the object Inside the body. A screen, is configured to display die position of the object inside the body.

公开(公告)号：WO2018022154A3

公开(公告)日：2018-02-01

申请号：PCT/US2017/029180

申请日：2017-04-24

Applicant: STC. UNM

Inventor： BRUECK, Steven, R.J. ,  FEEZELL, Daniel ,  RANDALL, John ,  BUSANI, Tito ,  BALLARD, Joshua, B. ,  BEHZADIRAD, Mahmoud ,  RISHINARAMANGALAM, Ashwin Krishnan

IPC: G01Q70/08 ,  G01Q70/16 ,  B82Y35/00

Abstract: Provided is a composite metal-wide-bandgap semiconductor tip for scanning tunneling microscopy and/or scanning, tunneling lithography, a method of forming, and a method for using the composite metal-wide-bandgap semiconductor tip.

公开(公告)号：WO2017136400A1

公开(公告)日：2017-08-10

申请号：PCT/US2017/015960

申请日：2017-02-01

Applicant: STC. UNM

Inventor： HALL, Pamela ,  CHACKERIAN, Bryce ,  PEABODY, David, S. ,  DALY, Seth, Michael ,  ELMORE, Brad ,  TRIPLETT, Kathleen

IPC: A61K39/085 ,  A61P31/04 ,  A61P37/04

CPC classification number: A61K39/085 ,  A61K2039/5258 ,  C12N2795/18123

Abstract: The present invention is directed to virus-like particles (VLPs) which are engineered to present epitopes from Staphylococcus aureus (SA), preferably autoinducing peptides (AIPs) which regulate quorum-sensing dependent virulence in this pathogen, or epitopes from SA toxins and leukocidins. These VLPs may be used to provide immunogenic compositions and efficacious vaccines. In a mouse model of SA dermonecrosis, vaccination with AIP-containing VLPs or SA toxin-containing VLPs induces protective immunity to limit the pathogenesis of SA infection and promote bacterial clearance.

Abstract translation: 本发明涉及经改造以呈递来自金黄色葡萄球菌（SA）的表位的病毒样颗粒（VLP），优选自体诱导肽（AIP），其调节该病原体中的群体感应依赖性毒力 ，或来自SA毒素和白细胞杀伤素的表位。 这些VLP可用于提供免疫原性组合物和有效疫苗。 在SA皮肤坏死的小鼠模型中，接种含AIP的VLP或含SA毒素的VLP诱导保护性免疫以限制SA感染的发病机理并促进细菌清除。

公开(公告)号：WO2017123651A1

公开(公告)日：2017-07-20

申请号：PCT/US2017/013042

申请日：2017-01-11

Applicant: STC. UNM ,  ZARKESH-HA, Payman ,  EDWARDS, Jeremy ,  SZAUTER, Paul

Inventor： ZARKESH-HA, Payman ,  EDWARDS, Jeremy ,  SZAUTER, Paul

IPC: C12Q1/68 ,  G01N27/414 ,  G01N33/543 ,  G01N27/447

CPC classification number: C12Q1/68 ,  C12Q1/6869 ,  G01N27/4146 ,  G01N27/447 ,  C12Q2565/607

Abstract: This disclosure describes, in one aspect, a method of electric-field-assisted nucleotide sequencing. Generally, the method includes performing an ion-sensitive nucleotide sequencing method, applying an electric field across the device while the nucleotide sequencing reactions are being performed so that ions released by the sequencing reactions are directed to contact with the ion-sensitive detector, and detecting at least a portion of the released ions in contact with the ion-sensitive detector.

Abstract translation: 本公开在一个方面描述了电场辅助核苷酸测序的方法。 通常，该方法包括执行离子敏感性核苷酸测序方法，在正在进行核苷酸测序反应的同时在设备上施加电场，使得由测序反应释放的离子指向与离子敏感检测器接触，并且检测 至少一部分释放的离子与离子敏感的检测器接触。

公开(公告)号：WO2015116935A1

公开(公告)日：2015-08-06

申请号：PCT/US2015/013781

申请日：2015-01-30

Applicant: STC. UNM

Inventor： BALAKRISHNAN, Ganesh ,  HAINS, Christopher ,  ARAGON, Andrew

IPC: H02S10/00

CPC classification number: H02S40/22 ,  G02B6/0008 ,  G02B6/42 ,  H01L31/0547 ,  H02J7/355 ,  H02S40/32 ,  H02S40/38 ,  Y02E10/52

Abstract: A device includes a body and a rechargeable battery positioned within the body. A solar cell is coupled to the body and in communication with the battery. A connector is coupled to the body and configured to engage a corresponding connector of a fiber optic cable.

Abstract translation: 一种装置包括主体和位于身体内的可充电电池。 太阳能电池耦合到身体并与电池连通。 连接器联接到主体并且被配置为接合光纤电缆的相应连接器。

公开(公告)号：WO2014165608A1

公开(公告)日：2014-10-09

申请号：PCT/US2014/032702

申请日：2014-04-02

Applicant: STC. UNM ,  SANDIA CORPORATION ,  ASHLEY, Carlee, Erin ,  CARNES, Eric, C. ,  WU, Terry ,  FELTON, Linda, A. ,  SASAKI, Darryl, Y.

Inventor： ASHLEY, Carlee, Erin ,  CARNES, Eric, C. ,  WU, Terry ,  FELTON, Linda, A. ,  SASAKI, Darryl, Y.

IPC: C12N11/14 ,  C12N11/08 ,  A61K35/66 ,  A61P31/00

CPC classification number: A61K31/7036 ,  A61K9/0053 ,  A61K9/1271 ,  A61K9/1274 ,  A61K9/5021 ,  A61K9/5123 ,  A61K31/505 ,  A61K31/5383 ,  A61K31/546 ,  A61K31/635 ,  A61K31/65 ,  A61K47/52 ,  A61K47/60 ,  A61K47/62 ,  A61K47/68 ,  A61K47/6913 ,  A61K47/6917 ,  A61K47/6923 ,  A61K47/6929 ,  B82Y5/00 ,  Y02A50/404 ,  Y02A50/406 ,  Y02A50/469 ,  Y02A50/471 ,  Y02A50/475 ,  Y02A50/478 ,  Y02A50/481

Abstract: The invention provides novel antibiotic protocells comprising mesoporous nanoparticles encapsulated within a lipid bi- or multilayer. The nanoparticles have pore sizes and surface chemistries that enable facile adsorption and intracellular presentation of antibiotics which are effective in the treatment of a wide variety of bacterial infections, including F. tularensis, B. pseudomallei and P. aeruginosa -related infections. Related pharmaceutical compositions and methods of treatment are also provided.

Abstract translation: 本发明提供了包含在脂质双层或多层中的介孔纳米颗粒的新型抗生素原细胞。 纳米颗粒具有孔径和表面化学物质，其能够容易地吸附和细胞内呈递抗生素，其有效治疗各种细菌感染，包括土拉木霉，假单胞菌和铜绿假单胞菌相关感染。 还提供了相关的药物组合物和治疗方法。

公开(公告)号：WO2013169391A1

公开(公告)日：2013-11-14

申请号：PCT/US2013/032428

申请日：2013-03-15

Applicant: STC. UNM ,  DATYE, Abhaya ,  PHAM, Hien

Inventor： DATYE, Abhaya ,  PHAM, Hien

IPC: C01B31/02 ,  C23C16/26 ,  B01J6/00

CPC classification number: C25D5/10 ,  B01J21/08 ,  B01J21/18 ,  B01J23/44 ,  B01J35/002 ,  B01J35/1019 ,  B01J35/1023 ,  B01J35/1038 ,  B01J35/1061 ,  B01J37/0018 ,  B01J37/0201 ,  B01J37/0215 ,  B01J37/343 ,  B01J37/348 ,  C01B32/05 ,  C25D5/50 ,  C25D5/505

Abstract: Catalyst support materials that are coated with a thin carbon over-layer and methods for making the same are shown and described. In general, a supporting oxide material, which may or may not have a catalytic material already deposited on the surface, is coated with a thin carbon layer.

Abstract translation: 显示和描述涂覆有薄碳层的催化剂载体材料及其制备方法。 通常，可以或可以不具有已经沉积在表面上的催化材料的支撑氧化物材料被涂覆有薄碳层。

公开(公告)号：WO2010008524A1

公开(公告)日：2010-01-21

申请号：PCT/US2009/004065

申请日：2009-07-14

Applicant: STC. UNM ,  SIBBETT, Scott, S. ,  LOPEZ, Gabriel, P.

Inventor： SIBBETT, Scott, S. ,  LOPEZ, Gabriel, P.

IPC: G01N33/53

CPC classification number: G01N33/558 ,  B01L3/5023 ,  B01L3/502746 ,  B01L2300/0825 ,  B01L2400/0406 ,  B01L2400/0421 ,  B01L2400/084 ,  G01N27/4473

Abstract: A lateral flow device includes a porous medium layer having a two-dimensional shape in plan view that is capable of supporting near-constant velocity capillary-driven fluid flow and can be combined with electrodes in a manner to achieve to achieve electrokinetic molecule separation.

Abstract translation: 侧流装置包括在平面图中具有二维形状的多孔介质层，其能够支持接近恒定速度的毛细管驱动的流体流动，并且可以以实现电动分子分离的方式与电极组合。

公开(公告)号：WO2020006178A1

公开(公告)日：2020-01-02

申请号：PCT/US2019/039417

申请日：2019-06-27

Applicant: STC. UNM

Inventor： PLUSQUELLIC, James ,  ARENO, Matt

IPC: H04L9/32 ,  G06F21/73

Abstract: A privacy-preserving, mutual PUF-based authentication protocol that uses soft data to exchange and correlate Helper Data bitstrings instead of PUF response bitstrings as a means of authenticating chips to prevent attacks.

公开(公告)号：WO2019210033A1

公开(公告)日：2019-10-31

申请号：PCT/US2019/029065

申请日：2019-04-25

Applicant: STC. UNM ,  MELLIOS, Nikolaos

Inventor： STC. UNM ,  MELLIOS, Nikolaos

IPC: C12Q1/6837 ,  C12Q1/6844 ,  C12Q1/6876

Abstract: A plurality of circular RNAs (circRNAs) the expression of which is correlated with brain disorders. The circRNAs are useful for compositions, kits, assays, and methods for the identification, diagnosis, screening, treatment and/or monitoring of brain disorders including psychiatric disorders such as bipolar disorder (BD), schizophrenia (SCZ), depression, Attention- Deficit/Hyperactivity Disorder (ADHD), Obsessive-compulsive disorder (OCD), Anxiety Disorders, etc., and neurodevelopmental disorders such as Autism, Asperger's Syndrome, and other Autism Spectrum Disorders (ASD), pervasive developmental disorders not otherwise specified (PDD-NOS), etc.