실크 피브로인 펩타이드를 유효성분으로 포함하는 골 이식재
    52.
    发明公开
    실크 피브로인 펩타이드를 유효성분으로 포함하는 골 이식재 有权
    包含丝状纤维蛋白肽作为活性成分的骨髓

    公开(公告)号:KR1020110121401A

    公开(公告)日:2011-11-07

    申请号:KR1020100040983

    申请日:2010-04-30

    CPC classification number: A61L27/22 A61F2/28 A61L27/225 A61L27/54 C07K1/12

    Abstract: PURPOSE: A bone graft material is provided to rapidly regenerate a damaged and lost part of bone by applying the bone graft material to the damaged and lost part of bone. CONSTITUTION: A bone graft material includes silk fibroin peptide as an active ingredient. The silk fibroin peptide has average molecular weight of 100-4,000 Da and is prepared by removing sericin by treating silk with alkaline solution and hydrolyzing the silk with acid. The silk fibroin peptide improves the expression of alkaline phosphatase, collagen type I-alpha 1, fibronectin, or transforming growth factor(TGF)-beta 1.

    Abstract translation: 目的:提供骨移植材料,通过将骨移植材料应用于损伤和丢失的骨头部分,快速再生骨骼损伤部分和损失部分。 构成:骨移植材料包括丝素蛋白肽作为活性成分。 丝素蛋白肽的平均分子量为100-4,000Da,通过用碱性溶液处理丝并用酸水解丝来除去丝胶蛋白。 丝素蛋白肽改善碱性磷酸酶,I-1型胶原,纤连蛋白或转化生长因子(TGF)-β1的表达。

    세포침투성 AMP-활성화 단백질 키나아제 및 그 용도
    54.
    发明公开
    세포침투성 AMP-활성화 단백질 키나아제 및 그 용도 无效
    细胞转导激活的蛋白激酶及其用途

    公开(公告)号:KR1020110061668A

    公开(公告)日:2011-06-10

    申请号:KR1020090118135

    申请日:2009-12-02

    Abstract: PURPOSE: An AMP-activated protein kinase fusion protein is provided to suppress inflammation by intracellular concentration-dependent and time-dependent introduction. CONSTITUTION: A cell permeable AMP-activated protein kinase fusion protein has a protein transport domain which is bound to at least one terminal of the AMP-activated protein kinase. The protein transport domain is PEP-1 peptide. The AMP-activated protein kinase has an amino acid of sequence number 7. A cosmetic composition contains the AMP-activated protein kinase as an active ingredient. A pharmaceutical composition for treating inflammation including type 2 diabetes, obesity, skin cancer, and atopic inflammation contains the AMP-activated protein kinase as an active ingredient and pharmaceutically acceptable carrier.

    Abstract translation: 目的:提供AMP激活的蛋白激酶融合蛋白,以通过细胞内浓度依赖性和时间依赖性介导来抑制炎症。 构成:细胞可渗透的AMP激活蛋白激酶融合蛋白具有蛋白转运结构域,其结合AMP活化蛋白激酶的至少一个末端。 蛋白质转运结构域是PEP-1肽。 AMP活化蛋白激酶具有序列号7的氨基酸。化妆品组合物含有AMP活化蛋白激酶作为活性成分。 用于治疗包括2型糖尿病,肥胖症,皮肤癌和特应性炎症的炎症的药物组合物含有AMP活化蛋白激酶作为活性成分和药学上可接受的载体。

    봉독을 유효성분으로 하는 여드름 예방 및 치료용 조성물
    56.
    发明公开
    봉독을 유효성분으로 하는 여드름 예방 및 치료용 조성물 有权
    包含用于治疗ACNE的BEE​​-VENOMS的组合物

    公开(公告)号:KR1020110011334A

    公开(公告)日:2011-02-08

    申请号:KR1020090068925

    申请日:2009-07-28

    CPC classification number: A61Q19/00 A61K8/987 A61K35/63 A61Q19/08 A61Q19/10

    Abstract: PURPOSE: A composition containing bee venom for preventing and treating acne is provided to ensure antibacterial activity to Propionibacterium acnes and to help regeneration of skin cells. CONSTITUTION: A composition for preventing or treating acne contains bee venom as an active ingredient. The concentration is 0.0001-10%(w/v). A cosmetic composition for preventing or treating acne contains bee venom as an active ingredient. A body cleansing instrument for preventing or treating acne contains bee venom as an active ingredient. The composition is manufactured in a form of liquids, creams, pastes, or solids. The composition additionally contains aqueous ingredient, oil ingredient, surfactant, moisturizer, tackifier, antiseptic and perfume.

    Abstract translation: 目的:提供含有预防和治疗痤疮的蜂毒组合物,以确保对丙酸杆菌的抗菌活性,并有助于皮肤细胞的再生。 构成:用于预防或治疗痤疮的组合物含有蜂毒作为活性成分。 浓度为0.0001-10%(w / v)。 用于预防或治疗痤疮的化妆品组合物含有蜂毒作为活性成分。 用于预防或治疗痤疮的身体清洁仪器含有蜂毒作为活性成分。 组合物以液体,霜剂,糊剂或固体的形式制造。 该组合物还含有水成分,油成分,表面活性剂,保湿剂,增粘剂,防腐剂和香料。

    저분자 실크 프로테인을 함유하는 화장품 조성물
    60.
    发明公开
    저분자 실크 프로테인을 함유하는 화장품 조성물 有权
    含有丝蛋白的化妆品组合物

    公开(公告)号:KR1020020096607A

    公开(公告)日:2002-12-31

    申请号:KR1020010035294

    申请日:2001-06-21

    CPC classification number: A61K8/64 A61K8/987 A61Q19/00 Y10S514/847

    Abstract: PURPOSE: A cosmetic composition with silk protein having excellent absorption properties, water vapor barrier properties, air permeability, etc. is provided which is excellent in product stability and long-term stability as well as a moisturizing effect and gives a natural, non-sticky feel during use. CONSTITUTION: The cosmetic composition contains 0.5 to 10.0% by weight of silk protein. The silk protein is low molecular silk protein obtained by removing soluble sericin, dissolving with a neutral salt and then hydrolyzing polymeric silk protein with protease such as actinase and/or neutrase after removing the salt. The composition is formulated into toilet soap, skin lotion, lotion, cream, pearl-off pack or bathing agent.

    Abstract translation: 目的:提供具有优异的吸收性,水蒸气阻隔性,透气性的丝蛋白的化妆品组合物,其产品稳定性和长期稳定性以及保湿效果优异,赋予天然,不粘 使用感觉 构成:化妆品组合物含有0.5-10.0重量%的丝蛋白。 丝蛋白是通过去除可溶性丝胶蛋白得到的低分子丝蛋白,用中性盐溶解,然后除去盐后用蛋白酶如肌动蛋白酶和/或中性粒子水解聚合丝蛋白。 将组合物配制成香皂,皮肤洗剂,洗剂,奶油,珍珠粉或洗浴剂。

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