Abstract:
PURPOSE: A bone cement composition is provided to secure biocompatible stiffness instead of overly high stiffness. CONSTITUTION: A bone cement composition includes: a powder part containing silk fibroin hydrolysate powder, polyacrylo-nitrile PMMA, and polymerization initiator; and a fluid part containing acrylic monomer, polymerization accelerator, and polymer inhibitor. The powder part and fluid part are mixed with each other. The silk fibroin hydrolysate powder has molecular weight 0.1-100 kDa.
Abstract:
PURPOSE: A bone graft material is provided to rapidly regenerate a damaged and lost part of bone by applying the bone graft material to the damaged and lost part of bone. CONSTITUTION: A bone graft material includes silk fibroin peptide as an active ingredient. The silk fibroin peptide has average molecular weight of 100-4,000 Da and is prepared by removing sericin by treating silk with alkaline solution and hydrolyzing the silk with acid. The silk fibroin peptide improves the expression of alkaline phosphatase, collagen type I-alpha 1, fibronectin, or transforming growth factor(TGF)-beta 1.
Abstract:
본 발명은 천연항생제 및 이의 제조방법에 관한 것으로서, 더 상세하게는 항산화 효과가 우수한 생약을 특정 열수 조건에서 추출한 추출물과 항균효과가 우수한 봉독을 유효성분으로 하는 천연항생제에 관한 것이다. 본 발명의 천연항생제는 돼지의 설사 유발균에 대한 살균 효과가 높아서 자돈의 질병 예방과 치료가 가능하여 자돈의 생산성을 향상시킬 수 있고 항생제가 잔류되지 않은 돈육을 제공할 수 있다. 그리고 젖소 유방염 유발균에 대한 살균력 또한 높기 때문에 젖소의 원유내 체세포 수를 현격히 낮출 수 있고, 기존 항생제를 대체할 수 있는 바, 원유내 항생제 잔류문제가 해결된 고품질 우유, 치즈 등의 유제품을 제공할 수 있다. 봉독, 인동초, 어성초, 인진쑥, 녹차, 항생제
Abstract:
PURPOSE: An AMP-activated protein kinase fusion protein is provided to suppress inflammation by intracellular concentration-dependent and time-dependent introduction. CONSTITUTION: A cell permeable AMP-activated protein kinase fusion protein has a protein transport domain which is bound to at least one terminal of the AMP-activated protein kinase. The protein transport domain is PEP-1 peptide. The AMP-activated protein kinase has an amino acid of sequence number 7. A cosmetic composition contains the AMP-activated protein kinase as an active ingredient. A pharmaceutical composition for treating inflammation including type 2 diabetes, obesity, skin cancer, and atopic inflammation contains the AMP-activated protein kinase as an active ingredient and pharmaceutically acceptable carrier.
Abstract:
PURPOSE: A silk/hydroxyapatite complex nanofiber supporter for osteanagenesis is provided to promote a cell growth promotion effect and to remove cytotoxin. CONSTITUTION: A silk/hydroxyapatite complex nanofiber supporter for osteanagenesis constituted as follows. In the nanofiber supporter, hydroxyapatite is coated on the surface thereof and silk nanofiber having the diameter of tens or hundreds nanometers is three-dimensionally arranged. The silk nanofiber maintains the form of a strand of fiber without conglomeration or entanglement thereof.
Abstract:
PURPOSE: A composition containing bee venom for preventing and treating acne is provided to ensure antibacterial activity to Propionibacterium acnes and to help regeneration of skin cells. CONSTITUTION: A composition for preventing or treating acne contains bee venom as an active ingredient. The concentration is 0.0001-10%(w/v). A cosmetic composition for preventing or treating acne contains bee venom as an active ingredient. A body cleansing instrument for preventing or treating acne contains bee venom as an active ingredient. The composition is manufactured in a form of liquids, creams, pastes, or solids. The composition additionally contains aqueous ingredient, oil ingredient, surfactant, moisturizer, tackifier, antiseptic and perfume.
Abstract:
본 발명은 신경 세포 보호 활성을 갖는 실크 펩타이드의 제조방법에 관한 것으로서, 보다 상세하게는 실크 단백질, 바람직하게는 실크 피브로인을 가수 분해하여 중량 평균 분자량이 300-100,000이고 신경 세포 보호 활성을 갖는 실크 펩타이드의 제조방법에 관한 것이다. 실크, 실크 펩타이드, 피브로인, 가수분해, 신경세포, 허혈
Abstract:
본 발명은 뇌신경질환의 예방 또는 치료용 조성물에 관한 것으로서, 보다 상세하게는 (a) 실크 단백질의 분해에 의해 생성된 실크 펩타이드의 약제학적 유효량; 및 (b) 약제학적 담체를 포함하는 뇌신경질환의 예방 또는 치료용 조성물에 관한 것이다. 실크, 실크 펩타이드, 피브로인, 아폽토시스, 허혈, 재관류, 뇌졸증, 아세틸콜린, 인지 기능, 우울증, 신경 퇴행성 질환, 기능성 식품
Abstract:
PURPOSE: A cosmetic composition with silk protein having excellent absorption properties, water vapor barrier properties, air permeability, etc. is provided which is excellent in product stability and long-term stability as well as a moisturizing effect and gives a natural, non-sticky feel during use. CONSTITUTION: The cosmetic composition contains 0.5 to 10.0% by weight of silk protein. The silk protein is low molecular silk protein obtained by removing soluble sericin, dissolving with a neutral salt and then hydrolyzing polymeric silk protein with protease such as actinase and/or neutrase after removing the salt. The composition is formulated into toilet soap, skin lotion, lotion, cream, pearl-off pack or bathing agent.