Abstract:
PURPOSE: A polymerase chain reaction(PCR) device and a method for regulating the opening/shutting of inlet and outlet of the same device are provided, thereby minimizing the size of the PCR device because the opening/shutting of inlet and outlet of the PCR device is regulated by microvalves which do not require an additional heat source. CONSTITUTION: The polymerase chain reaction(PCR) device(1) comprises the parts of: an inlet(3) through which biochemical fluid is introduced; an outlet(4) through which the biochemical fluid is released; a PCR reaction channel(5) which is positioned between the inlet and outlet; first and second microvalves(2a, 2b) which regulate the opening/shutting of inlet(3) and outlet(4) of the PCR device(5), wherein the microvalves(2a, 2b) contain a sol-gel material which is gelled under the temperature of DNA denaturation, annealing, and elongation, and above the room temperature, and is methyl cellulose.
Abstract:
PURPOSE: A method for replicating nucleic acid array is provided, thereby significantly reducing the costs and time for replicating nucleic acid array although the kinds or length of probes on the nucleic acid array are increased because the total of the second polynucleotides which is in-situ synthesized by using one nucleic acid array as a template are transferred into a new substrate. CONSTITUTION: The method for replicating nucleic acid array comprises the steps of: (i) fixing each first polynucleotide(2) having a nucleotide sequence complementary with a second polynucleotide and each first nucleic acid probe with a primer binding site(1) on a first substrate(10) to prepare a template nucleic acid array; (ii) binding a primer to the primer binding site(1) of each first nucleic acid probe fixed on the surface of the template nucleic acid array; (iii) in-situ synthesizing the second polynucleotide by using the primer from the first polynucleotide(2) as a template; and (iv) transferring the numerous synthesized second polynucleotides and seconds nucleic acid probes with the primer into a second substrate, wherein the first and second substrates are patterned with a metal membrane pattern or surface-treated with functional groups such as aldehyde, streptavidin or thiol; and the primer is universal primer.
Abstract:
PURPOSE: A structure having a micro channel, and a sensor and heaters directly contacting with fluid inside the micro channel, and a method for manufacturing the same are provided to reliably measure physical characteristics of the fluid flowing in the micro channel in real time. CONSTITUTION: A structure having a micro channel(50) includes a semiconductor substrate(48) having a predetermined length of groove for forming a micro channel, and a glass substrate(40) of which one side is joined with the groove-formed surface of the semiconductor substrate, a sensor(44) directly measuring physical characteristics of fluid flowing in the micro channel, a plurality of local heaters(46) directly heating the fluid at a random position in the micro channel, and a main heater(42) installed at a circumference of the micro channel.
Abstract:
PURPOSE: A method for detecting a binding state between biomolecules is provided to obtain a detecting result as an electric signal by measuring shear stress of a substrate without performing a separate labeling work. CONSTITUTION: Biomolecules of probes are attached to a surface of a substrate. Then, the biomolecules of the probes are reacted with a sample including target biomolecules. Shear stress of the substrate is measured before and after the biomolecules of the probes are reacted with the sample. Shear stress is measured by means of a shear stress measuring sensor(11) based on a phase shift and a force shift of a vibration motion. Biomolecules of the target and the probes include any one selected from the group consisting of DNA oligomer, nucleic acids, such as c-DNA, proteins, cofactors, oligosaccharides, and cell.
Abstract:
PURPOSE: A symmetrical z-axis micro gyroscope and a manufacturing method thereof are provided to reduce any manufacturing errors in the vibration resonance frequency and sensing resonance frequency by manufacturing supporting beams with flexibility in an angle of 45 degree with relation to x and y axes, thereby omitting the frequency tuning and improving the performance of the gyroscope. CONSTITUTION: A symmetrical z-axis micro gyroscope includes a supporting die, an inertial mass element(8) vibrating in a floating state above the supporting die, supporting beams, a sensing element for sensing an angula velocity measured by a displacement due to the vibration of the inertial mass element, and an element(15) for generating electrostatic force for vibrating the inertial mass element in parallel with the supporting die, wherein the supporting beams are formed in the structure having a flexibility in the vibration direction and the sensing direction and symmetrically disposed in the vibration and sensing directions.
Abstract:
영상 촬영 장치, 사용자 단말 장치 및 영상 촬영 장치와 사용자 단말 장치의 통신 방법이 제공된다. 본 영상 촬영 장치는 통신을 수행하기 위한 통신 모듈, 사용자 단말 장치와 태깅이 이루어지면, 상기 사용자 단말 장치와 근거리 무선 통신을 수행하여 상기 사용자 단말 장치로 연결 정보를 제공하는 근거리 무선 통신 모듈, 상기 통신 모듈이 비활성화된 상태에서 상기 태깅이 이루어지면 상기 통신 모듈을 활성화 상태로 전환하고, 상기 연결 정보 및 상기 활성화된 통신 모듈을 이용하여 상기 사용자 단말 장치와 통신을 자동으로 연결하는 제어부를 포함한다.
Abstract:
PURPOSE: A device for processing a digital image and a method for controlling the same are provided to set focur by a first signal and calculates a focus value by set time interval between a first signal and a second signal. CONSTITUTION: Focus is adjusted by obtaining a focus value according to input of a first signal(S420). The focus value by the focus adjustment is selected as a reference focus value(S430). Before inputting a second signal, an input image is inputted(S440). A current focus value corresponding to focus value of input image is calculated(S450). By comparing the focus value and the current focus value, a current focus state is determined(S460,S461,S462).
Abstract:
A method of sensing biomolecules in an electrolyte solution by using a bio FET. When it is sensed that probe biomolecules are immobilized to a gate surface of the bio FET or that the probe biomolecules are hybridized with target biomolecules, a Debye length from the biomolecules having charges attached to the gate surface is controlled.