公开(公告)号：KR1020040039571A

公开(公告)日：2004-05-12

申请号：KR1020020067683

申请日：2002-11-02

Applicant: 한국전자통신연구원

Inventor： 김성진 ,  신용범 ,  양해식 ,  박세호 ,  이대식 ,  윤태환 ,  김규원 ,  김윤태

IPC: B01F5/06

Abstract: PURPOSE: A microfluidic device applied to a biochip is provided to mix microfluid by disposing hot wires in a reaction chamber to form layers and heating or cooling stored fluids. CONSTITUTION: The microfluidic device for mixing microfluid comprises a first flow channel delivering a first fluid(106); a second flow channel delivering a second fluid(108); a reaction chamber connected to ends of the first and second flow channels and having hot wires(104) for heating the inside; and a part for stopping flow connected to end of the reaction chamber so as to prevent the first and second fluids from moving. When the first and second fluids meet in the reaction chamber and form layers, the first and second fluids are heated or cooled using the hot wires to generate the density difference, thereby mixing the first and second fluids by gravity.

Abstract translation: 目的：提供应用于生物芯片的微流体装置，通过在反应室中设置热丝以形成层并加热或冷却储存的流体来混合微流体。 构成：用于混合微流体的微流体装置包括：输送第一流体（106）的第一流动通道; 输送第二流体（108）的第二流动通道; 反应室连接到第一和第二流动通道的端部，并具有用于加热内部的热丝（104） 以及用于停止与反应室的端部连通的流动的部件，以防止第一和第二流体移动。 当第一和第二流体在反应室中相交并形成层时，使用热丝将第一和第二流体加热或冷却，以产生密度差，从而通过重力混合第一和第二流体。

公开(公告)号：KR1020040035104A

公开(公告)日：2004-04-29

申请号：KR1020020063838

申请日：2002-10-18

Applicant: 한국전자통신연구원

Inventor： 윤태환 ,  양해식 ,  이대식 ,  박세호 ,  신용범 ,  김규원 ,  김성진 ,  김윤태

IPC: C12Q1/68

Abstract: PURPOSE: A fluorescence detecting device for detecting biomolecule using amorphous-silicon thin film transistor and a method for detecting the fluorescence using the same are provided, thereby reducing the size and costs of DNA chip because optical devices are not used, and requiring no fluorescence stimulating light blocking filter by using a transparent substrate. CONSTITUTION: A fluorescence detecting device for detecting biomolecule using amorphous-silicon thin film transistor comprises a first substrate with a probe biomolecule; a transparent substrate(102) having a first domain(I), a second domain(II) and a third domain(III), and having a first surface(102a) where a light is irradiated and a second surface(102b) arranged to face the first substrate; a light thin film transistor(TFToptic) producing electric charge responding to the fluorescence produced from the biomolecule on the second surface(102b) and positioned in the first domain(I); a capacity(CAP) storing the electric charge produced from the light thin film transistor(TFToptic) and positioned in parallel to the light thin film transistor(TFToptic) in the second domain(II); and a transfer thin film transistor(TFTtrans) transferring the electric charge to an additional analysis system and positioned in parallel to the capacity(CAP) in the third domain(III).

Abstract translation: 目的：提供一种用于使用非晶硅薄膜晶体管检测生物分子的荧光检测装置和使用其的荧光检测方法，从而由于不使用光学器件而不需要荧光刺激而降低DNA芯片的尺寸和成本 遮光过滤器采用透明基板。 构成：使用非晶硅薄膜晶体管检测生物分子的荧光检测装置，包括具有探针生物分子的第一基底; 具有第一结构域（I），第二结构域（II）和第三结构域（III）的透明基板（102），并且具有照射光的第一表面（102a）和第二表面（102b） 面对第一衬底; 产生电荷的光薄膜晶体管（TFToptic），产生响应于由第二表面（102b）上的生物分子产生并位于第一域（I）中的荧光的电荷; 存储从所述光薄膜晶体管（TFT光电）产生并与所述第二域（II）中的所述薄膜晶体管（TFToptic）并行定位的电荷的容量（CAP）; 和转移薄膜晶体管（TFTtrans），其将电荷转移到另外的分析系统并且与第三域（III）中的容量（CAP）平行放置。