公开(公告)号：KR1020100066344A

公开(公告)日：2010-06-17

申请号：KR1020090095680

申请日：2009-10-08

Applicant: 한국전자통신연구원

Inventor： 홍효봉 ,  이수형 ,  김태완 ,  정명애 ,  손승원

IPC: C07K7/06 ,  A61K47/42 ,  G01N33/569 ,  C07K1/00

CPC classification number: A61K38/05 ,  C07K5/06026 ,  C07K5/06034 ,  C07K5/06052 ,  C07K5/0606 ,  C07K5/06069 ,  C07K5/06078 ,  C07K5/06086 ,  C07K5/06095 ,  C07K5/06104 ,  C07K5/06139

Abstract: PURPOSE: A peptide compound for detecting or suppressing avian influenza virus is provided to ensure easy synthesis and maintenance and to have strong binding force to H5 protein. CONSTITUTION: An agent for capturing and suppressing AI virus contains a compound of chemical formula 1. The agent for capturing and suppressing AI virus binds to H5 protein of AI virus. The AI virus is detected by contacting the compound of chemical formula 1 with a sample. A method for contacting the compound of chemical formula 1 with the sample comprises: a step of fixing the compound of chemical formula 1 or sample on a substrate surface; a step of contacting the compound of chemical formula 1 or the sample; a step of fixing the compound of chemical formula 1 on the surface of the substrate; and a step of contacting a capture material with a marker.

Abstract translation: 目的：提供用于检测或抑制禽流感病毒的肽化合物，以确保容易的合成和维持，并具有与H5蛋白的强结合力。 构成：用于捕获和抑制AI病毒的药剂含有化学式1的化合物。用于捕获和抑制AI病毒的药物与AI病毒的H5蛋白结合。 通过使化学式1的化合物与样品接触来检测AI病毒。 将化学式1的化合物与样品接触的方法包括：将化学式1或样品的化合物固定在基材表面上的步骤; 使化学式1或样品的化合物接触的步骤; 将化学式1的化合物固定在基材的表面上的步骤; 以及使捕获材料与标记物接触的步骤。

公开(公告)号：KR1020090119476A

公开(公告)日：2009-11-19

申请号：KR1020080045547

申请日：2008-05-16

Applicant: 한국전자통신연구원

Inventor： 홍효봉 ,  윤형중 ,  정명애

IPC: G01N33/48 ,  B41J2/00

CPC classification number: G01N33/54386 ,  G01N33/54393 ,  G01N33/54366

Abstract: PURPOSE: A method for producing a substrate pattern of biosensor is provided to reduce production cost and enhance fixation efficiency of biomass. CONSTITUTION: A method for producing a pattern of biosensor substrate comprises: a step of depositing silicon oxide film on a substrate; a step of forming polyethyleneimine layer on the silicon oxide film layer; a step of selectively masking a site to fix a biomass; and a step of irradiating the substrate with UV ray.

Abstract translation: 目的：提供生物传感器底物图案的制造方法，以降低生产成本，提高生物质的固定效率。 构成：用于制造生物传感器基板的图案的方法包括：在基板上沉积氧化硅膜的步骤; 在氧化硅膜层上形成聚乙烯亚胺层的步骤; 选择性地掩蔽位点以固定生物质的步骤; 以及用紫外线照射基板的步骤。

公开(公告)号：KR1020090065139A

公开(公告)日：2009-06-22

申请号：KR1020070132593

申请日：2007-12-17

Applicant: 한국전자통신연구원

Inventor： 홍효봉 ,  정명애 ,  정상돈 ,  윤형중

IPC: G01N33/53 ,  G01N33/48 ,  G01N30/02 ,  G01N30/00

Abstract: A detection method of signal of multiple biomolecules is provided to obtain the effects of test sample safety, high reliability of data and signal amplification of sample having minute amount using a photodegradable oligomer. A method for detecting a signal of multiple biomolecule comprises: a step of catching a target biomolecule as a probe in a sample; a step of binding photodegradable oligomer for detecting target biomolecule and nano particle with target biomolecule; and a step of lysing the binding site between nano particle and photodegradable oligomer and detecting the signal to the oligomer; The photodegradable oligomer is different from each other in the length and sequence with the target biomolecule.

Abstract translation: 提供多种生物分子信号的检测方法，以获得使用可光降解的低聚物测试样品安全性，数据的可靠性和具有微量的样品的信号扩增的效果。 一种检测多重生物分子信号的方法，包括：将目标生物分子作为探针捕获在样品中的步骤; 用靶标生物分子检测目标生物分子和纳米粒子的光可降解寡聚体结合步骤; 以及裂解纳米颗粒和可光降解低聚物之间的结合位点并检测到低聚物的信号的步骤; 光可降解低聚物在靶生物分子的长度和序列上彼此不同。