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公开(公告)号：KR1020170072630A
公开(公告)日：2017-06-27
申请号：KR1020150181042
申请日：2015-12-17
Applicant: 한국전자통신연구원
CPC classification number: C23F1/02 , C23F1/00 , C23F1/18 , C23F1/44 , C25D3/56 , C25D3/62 , C25D3/64 , C25D5/48
Abstract: 금속과고분자의접착방법은금속층을형성하는단계; 상기금속층상에나노다공성금속구조체를형성하는단계; 및상기나노다공성금속구조체내로고분자가침투되도록, 상기나노다공성금속구조체에고분자층을압축시키는단계를포함한다.
Abstract translation: 接合金属和聚合物的方法包括以下步骤：形成金属层; 在金属层上形成纳米多孔金属结构; 并且压缩纳米多孔金属结构上的聚合物层，使得聚合物渗透到纳米多孔金属结构中。
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2.发明公开
公开(公告)号：KR1020150092474A
公开(公告)日：2015-08-13
申请号：KR1020140012893
申请日：2014-02-05
Applicant: 한국전자통신연구원
IPC: C12Q1/58
CPC classification number: C12Q1/58 , C01G15/00 , C01G19/02 , C01G53/04 , C01P2004/16 , C01P2004/64 , C12N11/14 , C12Y305/01005
Abstract: 본 발명은 요소 분해 능력을 개선시킨 바이오 센서의 제조방법에 관한 것으로, 상기 방법은 기판 상에 금속산화물 나노 막대를 형성하는 단계; 상기 금속산화물 나노 막대 상에 NiO 나노 입자를 부착하는 단계; 및 상기 NiO 나노 입자 상에 요소 분해 효소를 고정시키는 단계를 포함하며, 이와 같은 방법을 통해 요소분해효소를 고정화하는 NiO 나노입자를 편평한 2차원 표면보다는 3차원 구조를 가지는 금속산화물 나노막대 표면에 고정시킴으로써 단위면적 또는 단위부피 당 고정되는 요소분해효소의 양을 증가시켜 요소분해능력을 개선시킬 수 있다.
Abstract translation: 本发明涉及提高尿素酶能力的生物传感器的制造方法。 该方法包括以下步骤：在基底上形成金属氧化物纳米棒; 将NiO纳米颗粒附着在金属氧化物纳米棒上; 并将脲酶固定在NiO纳米颗粒上。 通过将通过该方法将脲酶固定在具有三维结构而不是平面二维表面的金属氧化物纳米棒的表面上的NiO纳米颗粒固定化，可以通过增加固定脲酶的量来提高脲酶能力 单位面积或单位体积。
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公开(公告)号：KR1020150070922A
公开(公告)日：2015-06-25
申请号：KR1020140021814
申请日：2014-02-25
Applicant: 한국전자통신연구원 , 서울대학교산학협력단
CPC classification number: A61M1/285 , A61F2/02 , A61M1/1656 , A61M1/1694 , A61M2205/12
Abstract: 본발명은복막투석을기반으로투석액연속재생을통해체내요독을제거할수 있는휴대용인공신장기용투석시스템에관한것으로, 본발명에따른휴대용인공신장기용투석시스템은투석액주입및 배출이중도관의카테터; 상기카테터를통해복강내부로부터뽑아낸투석액에포함된요독물질에대한효소에의한이온화, 전기화학적분해에의한이온화및 전하물질부착을위한요독전하부여모듈; 이온농도분극에의한이온및 불순물을분리하여배출하는배출모듈; 투석액용질추가모듈; 상기배출모듈로부터분리되어나온이온, 불순물이포함되어있는초과수분을배출하여일시저장하는저장용기; 및상기요독전하부여모듈, 상기배출모듈, 상기투석액용질추가모듈및 저장용기의기능작동을조절하는제어모듈을포함하며, 휴대용인공신장기용투석시스템은복막투석시 사용하는투석액을교환하는수고없이연속적으로복막투석이가능하여, 이를통해한달에 1회정도만병원방문하고, 신체적부담이적고, 혈압조절이잘되며, 식사제한이적고, 일과여행이자유로운등의복막투석의장점을그대로가지고있게된다.
Abstract translation: 本发明是一种连续重放方法的便携式人造肾透析系统，其通过基于腹膜透析在透析液上连续回放从内部身体中除去尿毒症物质。 根据本发明的便携式人造肾透析系统包括：具有用于注入和排出透析液的双管的导管; 尿素物质电荷提供模块，其通过酶进行电离和电化学分解，并且通过导管从腹腔抽取的透析液中包含的尿毒症材料的带电材料附着; 放电模块，其分离和排出由于离子浓度极化而产生的离子和杂质; 透析液溶质添加模块; 存储容器，其提取和暂时存储离子中包含的过多水分和从排出模块分离和排出的杂质; 控制模块，其控制尿素材料充电提供模块，放电模块，透析液溶质添加模块和存储容器的功能。 根据本发明，可以连续进行透水进入腹腔，而不需要更换所使用的透析液，使得患者可以每周一次在医院进行一次检查，身体负担减轻，血压控制好， 对工作和旅行的食物摄入和更自由的生活方式的限制很小。
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公开(公告)号：KR1020140042353A
公开(公告)日：2014-04-07
申请号：KR1020120109029
申请日：2012-09-28
Applicant: 한국전자통신연구원
Abstract: An electrode array according to an embodiment of the present invention comprises: a first electrode on a substrate; a second electrode arranged on the first electrode, and having the upper side and the lower side opposed to each other; an electrode supporter coming in contact with the second electrode and having an inner surface and an outer surface perpendicular to the substrate; and a third electrode coming in contact with the upper side of the second electrode and the inner surface of the electrode supporter. The electrode array of the present invention has an improved impedance performance, and an improved interface between a biological tissue and the electrode.
Abstract translation: 根据本发明实施例的电极阵列包括：基板上的第一电极; 布置在所述第一电极上并具有彼此相对的上侧和下侧的第二电极; 与第二电极接触并且具有垂直于衬底的内表面和外表面的电极支撑件; 以及与第二电极的上侧和电极支撑体的内表面接触的第三电极。 本发明的电极阵列具有改善的阻抗性能，以及生物组织和电极之间改进的界面。
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公开(公告)号：KR1020130063777A
公开(公告)日：2013-06-17
申请号：KR1020110130324
申请日：2011-12-07
Applicant: 한국전자통신연구원
IPC: A61B5/0478 , G03F7/20 , B82B3/00 , B82Y5/00
CPC classification number: A61B5/0478 , B82B3/009 , B82Y5/00 , G03F7/20
Abstract: PURPOSE: A surface treatment method for a neural electrode array using a zinc oxide nanowire is provided to allow the array to have surface roughness using the nanowire and to form a neuron adhesion material on the nanowire, thereby stably growing a neuron on the front surface of the array. CONSTITUTION: A surface treatment method for a neural electrode array(10) using a zinc oxide nanowire(31) includes the following steps: a step of preparing the array; a step of forming a metal seed layer on the array; a step of etching the metal seed layer; a step of growing the nanowire on the metal seed layer which is not removed in the previous step of etching; and a step of forming a neuron adhesion material(41) on the nanowire.
Abstract translation: 目的：提供使用氧化锌纳米线的神经电极阵列的表面处理方法，以使阵列具有使用纳米线的表面粗糙度，并在纳米线上形成神经元粘附材料，从而稳定地生长在前表面上的神经元 阵列。 构成：使用氧化锌纳米线（31）的神经电极阵列（10）的表面处理方法包括以下步骤：准备阵列的步骤; 在阵列上形成金属种子层的步骤; 蚀刻金属种子层的步骤; 在前面的蚀刻步骤中在金属种子层上生长纳米线的步骤，其不被去除; 以及在纳米线上形成神经元粘附材料（41）的步骤。
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Patent Agency Ranking
公开(公告)号：KR101118223B1
公开(公告)日：2012-03-16
申请号：KR1020090089686
申请日：2009-09-22
Applicant: 한국전자통신연구원
Abstract: 본 발명은 역 구조 기판 식각에 기반한 자기저항 측정 바이오센서 및 그의 제조방법에 관한 것이다. 본 발명의 바이오센서는 유전체층을 먼저 형성한 후 자기저항센서를 형성함으로써, 자기저항센서의 안정성에 손상을 가하지 않고 유전체층을 고온에서 형성할 수 있다. 따라서, 본 발명의 바이오센서는 고품질의 유전체층 박막을 포함하며, 그에 따르는 우수한 측정감도를 갖는다. 또한, 별도의 공정 없이 기판의 식각에 의하여 시료접촉 금속막 상에 시료적용 용기가 형성되므로 시료의 적용이 매우 편리하다.
자기저항센서, 바이오센서, 유전체층, 기판식각-
公开(公告)号：KR1020100066947A
公开(公告)日：2010-06-18
申请号：KR1020080125473
申请日：2008-12-10
Applicant: 한국전자통신연구원
CPC classification number: A61N1/0529 , A61N1/0551
Abstract: PURPOSE: An electrode for cerebral nerve stimulus and a substrate for cerebral nerve stimulus are provided to easily insert metal wire and to apply the metal wire in various forms. CONSTITUTION: An electrode(20) for the cerebral nerve stimulus comprises; a glass fiber(210) including a first hole(211) and second hole(212), and a metal wire(220) which is placed inside the first hole. The diameter of the first and second holes is 20-100um. The diameter of electrode for cerebral nerve stimulus is 100-290 um. The glass fiber and metal wire are fixed with thermal or photocurable polymer. The substrate comprises: a glass substrate on which a plurality of electrode insertion regions are located; an electrode for the cerebral nerve stimulus placed at a plurality of electrode insertion regions; and a connector connecting the electrode.
Abstract translation: 目的：提供脑神经刺激用电极和脑神经刺激底物，以容易地插入金属丝，并以各种形式施加金属丝。 构成：用于脑神经刺激的电极（20）包括： 包括第一孔（211）和第二孔（212）的玻璃纤维（210）和放置在第一孔内的金属线（220）。 第一孔和第二孔的直径为20-100um。 脑神经刺激电极的直径为100-290um。 玻璃纤维和金属丝用热或光固化的聚合物固定。 基板包括：玻璃基板，多个电极插入区域位于该玻璃基板上; 放置在多个电极插入区域的用于脑神经刺激的电极; 以及连接电极的连接器。
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公开(公告)号：KR1020090038597A
公开(公告)日：2009-04-21
申请号：KR1020070103969
申请日：2007-10-16
Applicant: 한국전자통신연구원
IPC: G01N33/53 , G01N33/543 , G01N33/554
Abstract: A signal detecting method for the extremely small amount of bio-molecule using photodegradable oligomer and nano-particles is provided to enable an operator to obtain amplified signals more than those of the actual amount of bio-molecule by labeling the photodegradable oligomer on the nano-particles coupled with bio-molecules. A signal detecting method for the extremely small amount of bio-molecule comprises the following steps of: catching a target bio-molecule in a sample with a probe; coupling the caught target bio-molecule with nano-particles; coupling the nano-particles with a photodegradable oligomer; and decomposing a boding site of the nano-particles and the photodegradable oligomer through light irradiation and detecting signals of target bio-molecule from the oligomer obtained by decomposition.
Abstract translation: 提供了使用光可降解低聚物和纳米颗粒的极小量的生物分子的信号检测方法，以使得操作者能够通过在纳米尺度上标记可光降解的低聚物来获得比实际量的生物分子更多的信号， 颗粒与生物分子结合。 用于极小量生物分子的信号检测方法包括以下步骤：用探针捕获样品中的靶生物分子; 将捕获的目标生物分子与纳米颗粒结合; 将纳米颗粒与可光降解的低聚物偶联; 并通过光照射分解纳米颗粒和光可降解低聚物的掺杂位点，并从通过分解获得的低聚物中检测目标生物分子的信号。
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公开(公告)号：KR100466545B1
公开(公告)日：2005-01-15
申请号：KR1020020008662
申请日：2002-02-19
Applicant: 한국전자통신연구원
Abstract: The present invention relates to a method of manufacturing polymer nano particle having two-photon absorption compound at its central portion. The method of manufacturing polymer nano particle comprises the steps of dispersing a monomer for forming polymer nano particle and two-photon absorption compound into a solvent; supplying a given gas while stirring the solvent in which the monomer and the two-photon absorption compound are dispersed at a given temperature, in order to remove the dissolved oxygen contained in the solvent; supplying polymerization initiators into the solvent while stirring the solvent in which the monomer and the two-photon absorption compound are dispersed at a given temperature; and polymerizing the monomer for a given period of time while stirring the solvent in which the monomer and the two-photon absorption compound are dispersed at a given temperature.
Abstract translation: 本发明涉及一种制造在其中心部分具有双光子吸收化合物的聚合物纳米颗粒的方法。 制造聚合物纳米颗粒的方法包括以下步骤：将用于形成聚合物纳米颗粒和双光子吸收化合物的单体分散到溶剂中; 在给定温度下搅拌其中分散有单体和双光子吸收化合物的溶剂的同时供给给定的气体，以除去溶剂中所含的溶解氧; 在给定温度下搅拌其中分散有单体和双光子吸收化合物的溶剂的同时将聚合引发剂供给到溶剂中; 在给定温度下搅拌分散有单体和双光子吸收化合物的溶剂的同时，将单体聚合一段给定的时间。
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公开(公告)号：KR1020030072658A
公开(公告)日：2003-09-19
申请号：KR1020020011785
申请日：2002-03-06
Applicant: 한국전자통신연구원
Abstract: PURPOSE: A self-assembled body of block copolymers of which chromopores are nano-encapsulated is provided to obtain a high absorption efficiency without phase separation. CONSTITUTION: The self-assembled body of block copolymers of which chromophores(30) are nano-encapsulated comprises multiple block copolymers having a structure including a polymer chain block(10) consisting of a first monomer and a polymer chain block(20) consisting of a second lyophilic monomer connected each other. Particularly, the self-assembled body of block copolymers comprises particles having a core-shell structure in which the lyophilic polymer chain block(20) is positioned in the shell, the other polymer chain block is positioned in the core, and the chromophores(30) are present in the core.
Abstract translation: 目的：提供一种自组装体，其中发色团为纳米封装的嵌段共聚物，以获得无相分离的高吸收效率。 构成：其中发色团（30）是纳米封装的嵌段共聚物的自组装体包含多个嵌段共聚物，其具有包含由第一单体和聚合物链块（20）组成的聚合物链嵌段（20）的结构，所述聚合物链嵌段 第二亲液单体相互连接。 特别地，嵌段共聚物的自组装体包括具有核 - 壳结构的颗粒，其中亲液聚合物链块（20）位于壳中，另一聚合物链块位于芯中，并且发色团（30 ）存在于核心。
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