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公开(公告)号：HRP20170514T1
公开(公告)日：2017-06-02
申请号：HRP20170514
申请日：2017-03-30
Applicant: AMGEN INC
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公开(公告)号：AU2012238247B2
公开(公告)日：2016-06-16
申请号：AU2012238247
申请日：2012-10-08
Applicant: AMGEN INC , UCB PHARMA SA
Inventor： WINTERS AARON GEORGE , LAWSON ALASTAIR , HENRY ALISTAIR JAMES , POPPLEWELL ANDY , PASZTY CHRISTOPHER , SHEN WENYAN , LU HSIENG SEN , LATHAM JOHN , HOFFMANN KELLY SUE , GRAHAM KEVIN , ROBINSON MARTYN KIM , WINKLER DAVID
Abstract: C:\NRPorbl\DCCSZPWA6573 I DOC.4/10/2012 Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided. 4v Lu L % 6 Iii cc ~ O O. . .U te,, Lo~ .CD C; L 0ZDB aweI
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公开(公告)号：HUE025530T2
公开(公告)日：2016-04-28
申请号：HUE10014362
申请日：2006-04-28
Applicant: AMGEN INC
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公开(公告)号：GEP20166454B
公开(公告)日：2016-04-11
申请号：GEAP2006012335
申请日：2006-04-28
Applicant: UCB PHARMA SA , AMGEN INC
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
Abstract: An invention relates to antibodies binding sclerostin epitopes, which crossly block Ab-C, Ab-D, Ab-13 or Ab-14 binding with sclerostin sequ¬ences SEQ ID NO: 1. Said antibodies are applied at the treatment of diseases related to abnormalities in bone mineral density and of bone mass.
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公开(公告)号：SI2325199T1
公开(公告)日：2015-07-31
申请号：SI200631933
申请日：2006-04-28
Applicant: AMGEN INC
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Patent Agency Ranking
公开(公告)号：PT2325199E
公开(公告)日：2015-07-10
申请号：PT10014362
申请日：2006-04-28
Applicant: AMGEN INC
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公开(公告)号：PL1891101T3
公开(公告)日：2013-11-29
申请号：PL06751903
申请日：2006-04-28
Applicant: AMGEN INC
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公开(公告)号：ES2412857T3
公开(公告)日：2013-07-12
申请号：ES06751903
申请日：2006-04-28
Applicant: UCB PHARMA SA , AMGEN INC
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTYN , GRAHAM KEVIN , HENRY ALISTAIR , HOFFMANN KELLY , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON
Abstract: Un anticuerpo de unión a esclerostina que comprende las siguientes secuencias de CDR: CDR-H1: DYNMH (SEC ID Nº: 245); CDR-H2: EINPNSGGAGYNQKFKG (SEC ID Nº: 246); CDR-H3: LGYDDIYDDWYFDV (SEC ID Nº: 247); CDR-L1: RASQDISNYLN (SEC ID Nº: 78); CDR-L2: YTSRLLS (SEC ID Nº: 79); y CDR-L3: QQGDTLPYT (SEC ID Nº: 80).
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公开(公告)号：GEP20125594B
公开(公告)日：2012-08-10
申请号：GEAP2006010403
申请日：2006-04-28
Applicant: UCB PHARMA SA , AMGEN INC
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWEL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
Abstract: There are represented sclerostin binding sequences or amino acid sequences determining segments complementarity in (CDR) antibodies blocking binding and isolated coding polynucleotide sequences thereof, pharmaceutical compositions containing said antibodies and their usage at the treatment of diseases associated with sclerostin, particularly, with bone mineralization related diseases.
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公开(公告)号：MA29528B1
公开(公告)日：2008-06-02
申请号：MA30433
申请日：2007-11-29
Applicant: UCB PHARMA SA , AMGEN INC
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
Abstract: L'INVENTION CONCERNE DES COMPOSITIONS ET DES PROCÉDÉS AYANT TRAIT AUX ÉPITOPES DE LA PROTÉINE SCLÉROSTINE, ET DES AGENTS DE FIXATION À LA SCLÉROSTINE TELS QUE DES ANTICORPS POUVANT SE FIXER À LA SCLÉROSTINE
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